NO962899D0 - Cykliske polyaminer - Google Patents

Cykliske polyaminer

Info

Publication number
NO962899D0
NO962899D0 NO962899A NO962899A NO962899D0 NO 962899 D0 NO962899 D0 NO 962899D0 NO 962899 A NO962899 A NO 962899A NO 962899 A NO962899 A NO 962899A NO 962899 D0 NO962899 D0 NO 962899D0
Authority
NO
Norway
Prior art keywords
pct
sec
date
polyamine
cyclic
Prior art date
Application number
NO962899A
Other languages
English (en)
Other versions
NO962899L (no
NO309680B1 (no
Inventor
Gary James Bridger
Sreenivasan Padmanabhan
Renato Tony Skerlj
Original Assignee
Johnson Matthey Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson Matthey Plc filed Critical Johnson Matthey Plc
Publication of NO962899L publication Critical patent/NO962899L/no
Publication of NO962899D0 publication Critical patent/NO962899D0/no
Publication of NO309680B1 publication Critical patent/NO309680B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Lubricants (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Biological Depolymerization Polymers (AREA)
NO962899A 1994-01-11 1996-07-10 Cykliske polyaminer, fremgangsmåte for fremstilling derav og farmasöytisk preparat inneholdende slike NO309680B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9400411A GB9400411D0 (en) 1994-01-11 1994-01-11 Improvements in chemical compounds
PCT/GB1995/000019 WO1995018808A1 (en) 1994-01-11 1995-01-06 Cyclic polyamines

Publications (3)

Publication Number Publication Date
NO962899L NO962899L (no) 1996-07-10
NO962899D0 true NO962899D0 (no) 1996-07-10
NO309680B1 NO309680B1 (no) 2001-03-12

Family

ID=10748627

Family Applications (1)

Application Number Title Priority Date Filing Date
NO962899A NO309680B1 (no) 1994-01-11 1996-07-10 Cykliske polyaminer, fremgangsmåte for fremstilling derav og farmasöytisk preparat inneholdende slike

Country Status (14)

Country Link
US (1) US5698546A (no)
EP (1) EP0739345B1 (no)
JP (1) JP3749253B2 (no)
AT (1) ATE236906T1 (no)
AU (1) AU681478B2 (no)
CA (1) CA2179530C (no)
DE (1) DE69530281T2 (no)
ES (1) ES2191699T3 (no)
FI (1) FI962810A (no)
GB (1) GB9400411D0 (no)
HU (1) HU219238B (no)
NO (1) NO309680B1 (no)
NZ (1) NZ277859A (no)
WO (1) WO1995018808A1 (no)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
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GB9511357D0 (en) * 1995-06-06 1995-08-02 Johnson Matthey Plc Improved antiviral compounds
US6506770B1 (en) * 1996-06-06 2003-01-14 Anormed, Inc. Antiviral compounds
US6365583B1 (en) 1999-02-02 2002-04-02 Anormed, Inc. Methods to enhance white blood cell count
US6750348B1 (en) * 1999-03-24 2004-06-15 Anormed, Inc. Chemokine receptor binding heterocyclic compounds
ATE327988T1 (de) * 1999-03-24 2006-06-15 Anormed Inc Chemokine rezeptor bindende heterozyklische verbindungen
EP1244648B1 (en) * 1999-12-17 2009-04-15 Genzyme Corporation Chemokine receptor binding heterocyclic compounds
DK1317451T3 (da) * 2000-09-15 2006-12-18 Anormed Inc Kemokinreceptorbindende heterocykliske forbindelser
ES2325909T3 (es) 2000-09-15 2009-09-24 Anormed Inc. Compuestos heterociclicos que se unen a los receptores de quimioquinas.
SG126006A1 (en) 2000-09-15 2006-10-30 Anormed Inc Chemokine receptor binding heterocyclic compounds
EP1322626B1 (en) 2000-09-29 2008-11-05 Anormed Inc. Process for preparation of n-1 protected n ring nitrogen containing cyclic polyamines and products thereof
WO2003011277A2 (en) * 2001-07-31 2003-02-13 Anormed Inc. Methods to mobilize progenitor/stem cells
US7169750B2 (en) * 2001-07-31 2007-01-30 Anormed, Inc. Methods to mobilize progenitor/stem cells
BR0212443A (pt) * 2001-09-12 2005-03-15 Anormed Inc Sìntese de anéis bicìclicos fundidos, amino substituìdos enanciomericamente puros
US7354932B2 (en) * 2001-12-21 2008-04-08 Anormed, Inc. Chemokine receptor binding heterocyclic compounds with enhanced efficacy
KR20040068339A (ko) 2001-12-21 2004-07-30 아노르메드 인코포레이티드 효능이 강화된 케모카인 수용체 결합 헤테로사이클릭 화합물
WO2004091518A2 (en) 2003-04-11 2004-10-28 Anormed Inc. Cxcr4 chemokine receptor binding compounds
US7501518B2 (en) * 2003-04-22 2009-03-10 Genzyme Corporation Methods of making 2,6-diaryl piperidine derivatives
RU2005136224A (ru) * 2003-04-22 2006-06-10 Анормед Инк. (Ca) Гетероциклические соединения, связывающиеся с рецепторами хемокинов и обладающие повышенной эффективностью
US7498346B2 (en) * 2003-12-11 2009-03-03 Genzyme Corporation Chemokine receptor binding compounds
CA2548393A1 (en) 2003-12-11 2005-06-30 Anormed Inc. Chemokine receptor binding compounds
EP1730113B1 (en) * 2004-03-15 2016-12-28 Genzyme Corporation Process for the synthesis of a cxcr4 antagonist
JP2008509928A (ja) * 2004-08-13 2008-04-03 アノーメド インコーポレイテッド 前駆／幹細胞を動員するためのケモカインの組み合わせ
TW200619206A (en) * 2004-09-29 2006-06-16 Anormed Inc Chemokine-binding heterocyclic compound salts, and methods of use thereof
US7790747B2 (en) * 2005-06-15 2010-09-07 Genzyme Corporation Chemokine receptor binding compounds
CA2619881A1 (en) * 2005-08-16 2007-02-22 Genzyme Corporation Chemokine receptor binding compounds
BRPI0615180A2 (pt) * 2005-08-19 2011-05-03 Genzyme Corp método para intensificar a quimioterapia
ES2497092T3 (es) * 2006-02-24 2014-09-22 Genzyme Corporation Procedimientos para el aumento del flujo sanguíneo y/o la estimulación de la regeneración de tejidos
JP2010507567A (ja) * 2006-08-07 2010-03-11 ジェンザイム・コーポレーション 併用療法
WO2009114614A2 (en) * 2008-03-11 2009-09-17 Yale University Compositions and methods for controlled delivery of inhibitory ribonucleic acids
US9822364B2 (en) 2008-03-11 2017-11-21 Yale University Compositions and methods for controlled delivery of inhibitory ribonucleic acids
JP2014513727A (ja) 2011-05-16 2014-06-05 ジェンザイム・コーポレーション Ｃｘｃｒ４拮抗薬の使用
US10465042B2 (en) 2011-12-02 2019-11-05 Yale University Poly(amine-co-ester) nanoparticles and methods of use thereof
WO2013082529A1 (en) 2011-12-02 2013-06-06 Yale University Enzymatic synthesis of poly(amine-co-esters) and methods of use thereof for gene delivery
US9895451B2 (en) 2011-12-02 2018-02-20 Yale University Formulations for targeted release of agents to low pH tissue environments or cellular compartments and methods of use thereof
US11918695B2 (en) 2014-05-09 2024-03-05 Yale University Topical formulation of hyperbranched polymer-coated particles
US10272019B2 (en) 2014-05-09 2019-04-30 Yale University Topical formulation of hyperbranched polyglycerol-coated particles thereof
WO2016081621A1 (en) 2014-11-18 2016-05-26 Yale University Formulations for targeted release of agents under low ph conditions and methods of use thereof
US10682422B2 (en) 2014-11-18 2020-06-16 Yale University Formulations for targeted release of agents under low pH conditions and methods of use thereof
WO2016191811A1 (en) 2015-06-03 2016-12-08 The University Of Queensland Mobilizing agents and uses therefor
CA3008279A1 (en) 2015-12-14 2017-06-22 X4 Pharmaceuticals, Inc. Methods for treating cancer
US10953003B2 (en) 2015-12-14 2021-03-23 X4 Pharmaceuticals, Inc. Methods for treating cancer
CA3009176A1 (en) 2015-12-22 2017-06-29 X4 Pharmaceuticals, Inc. Methods for treating immunodeficiency disease
EP3416976A2 (en) 2016-02-16 2018-12-26 Yale University Compositions for enhancing targeted gene editing and methods of use thereof
CA3014795A1 (en) 2016-02-16 2017-08-24 Yale University Compositions and methods for treatment of cystic fibrosis
JP2019510785A (ja) 2016-04-08 2019-04-18 エックス４ ファーマシューティカルズ， インコーポレイテッド 癌を処置する方法
WO2017197128A1 (en) 2016-05-11 2017-11-16 Yale University Poly(amine-co-ester) nanoparticles and methods of use thereof
CN109640988A (zh) 2016-06-21 2019-04-16 X4 制药有限公司 Cxcr4抑制剂及其用途
JP6994767B2 (ja) 2016-06-21 2022-01-14 エックス４ ファーマシューティカルズ， インコーポレイテッド Ｃｘｃｒ４阻害剤およびその使用
CN116554168A (zh) 2016-06-21 2023-08-08 X4 制药有限公司 Cxcr4抑制剂及其用途
WO2018187493A1 (en) 2017-04-04 2018-10-11 Yale University Compositions and methods for in utero delivery
CN111683669A (zh) 2017-10-31 2020-09-18 美真达治疗公司 用于造血干细胞和祖细胞移植疗法的组合物和方法
WO2019089826A1 (en) 2017-10-31 2019-05-09 Magenta Therapeutics Inc. Compositions and methods for the expansion of hematopoietic stem and progenitor cells
AU2018378804A1 (en) 2017-12-06 2020-06-11 Ensoma, Inc. Dosing regimens for the mobilization of hematopoietic stem and progenitor cells
US11260079B2 (en) 2017-12-06 2022-03-01 Magenta Therapeutics, Inc. Dosing regimens for the mobilization of hematopoietic stem and progenitor cells
JP2021510150A (ja) 2018-01-03 2021-04-15 マジェンタ セラピューティクス インコーポレイテッドＭａｇｅｎｔａ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． 造血幹細胞および前駆細胞の増幅ならびに遺伝性代謝障害の処置のための組成物および方法
US20210189431A1 (en) 2018-08-10 2021-06-24 Yale University Compositions and methods for embryonic gene editing in vitro
US10548889B1 (en) 2018-08-31 2020-02-04 X4 Pharmaceuticals, Inc. Compositions of CXCR4 inhibitors and methods of preparation and use
US11814464B2 (en) 2019-04-29 2023-11-14 Yale University Poly(amine-co-ester) polymers and polyplexes with modified end groups and methods of use thereof
WO2020257779A1 (en) 2019-06-21 2020-12-24 Yale University Hydroxymethyl-modified gamma-pna compositions and methods of use thereof
US20220243211A1 (en) 2019-06-21 2022-08-04 Yale University Peptide nucleic acid compositions with modified hoogsteen binding segments and methods of use thereof
US20220280656A1 (en) 2019-07-31 2022-09-08 Yale University Compositions and methods for treating sickle cell disease
US20220401481A1 (en) 2019-11-01 2022-12-22 Magenta Therapeutics, Inc. Dosing regimens for the mobilization of hematopoietic stem and progenitor cells
CN115997009A (zh) 2020-04-27 2023-04-21 美真达治疗公司 用于在体内转导造血干细胞和祖细胞的方法和组合物
JP2023531444A (ja) 2020-06-19 2023-07-24 イェール ユニバーシティー 改変された末端基および増強された肺送達を有するポリ（アミン－ｃｏ－エステル）ポリマー
US20220031633A1 (en) 2020-07-28 2022-02-03 Yale University Poly(amine-co-ester) polymeric particles for selective pulmonary delivery
EP4308694A1 (en) 2021-03-16 2024-01-24 Magenta Therapeutics, Inc. Dosing regimens for hematopoietic stem cell mobilization for stem cell transplants in multiple myeloma patients
CA3240407A1 (en) 2021-12-08 2023-06-07 Akiko Iwasaki Nanoparticle immunogenic compositions and vaccination methods
WO2023159189A1 (en) 2022-02-18 2023-08-24 Yale University Branched poly(amine-co-ester) polymers for more efficient nucleic expression

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5021409A (en) * 1989-12-21 1991-06-04 Johnson Matthey Plc Antiviral cyclic polyamines
GB9126677D0 (en) * 1991-12-16 1992-02-12 Johnson Matthey Plc Improvements in chemical compounds

Also Published As

Publication number Publication date
DE69530281T2 (de) 2004-01-29
JPH09509407A (ja) 1997-09-22
US5698546A (en) 1997-12-16
ATE236906T1 (de) 2003-04-15
GB9400411D0 (en) 1994-03-09
JP3749253B2 (ja) 2006-02-22
HU219238B (en) 2001-03-28
EP0739345B1 (en) 2003-04-09
CA2179530A1 (en) 1995-07-13
AU681478B2 (en) 1997-08-28
NO962899L (no) 1996-07-10
NO309680B1 (no) 2001-03-12
HU9601892D0 (en) 1996-09-30
EP0739345A1 (en) 1996-10-30
NZ277859A (en) 1997-07-27
CA2179530C (en) 2005-07-05
HUT74429A (en) 1996-12-30
FI962810A0 (fi) 1996-07-10
AU1324595A (en) 1995-08-01
ES2191699T3 (es) 2003-09-16
DE69530281D1 (de) 2003-05-15
WO1995018808A1 (en) 1995-07-13
FI962810A (fi) 1996-07-10

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