| GB9304919D0
              (en)
            
            * | 1993-03-10 | 1993-04-28 | Celltech Ltd | Chemical compounds | 
        
          | CA2185019C
              (en)
            
            * | 1994-03-09 | 2000-08-08 | Pfizer Limited | Isoxazoline compounds as inhibitors of tnf release | 
        
          | US5786354A
              (en)
            
            * | 1994-06-21 | 1998-07-28 | Celltech Therapeutics, Limited | Tri-substituted phenyl derivatives and processes for their preparation | 
        
          | US6245774B1
              (en)
            
            * | 1994-06-21 | 2001-06-12 | Celltech Therapeutics Limited | Tri-substituted phenyl or pyridine derivatives | 
        
          | GB9412573D0
              (en) | 1994-06-22 | 1994-08-10 | Celltech Ltd | Chemical compounds | 
        
          | GB9412571D0
              (en) | 1994-06-22 | 1994-08-10 | Celltech Ltd | Chemical compounds | 
        
          | GB9523675D0
              (en) | 1995-11-20 | 1996-01-24 | Celltech Therapeutics Ltd | Chemical compounds | 
        
          | CA2258728C
              (en) | 1996-06-19 | 2011-09-27 | Rhone Poulenc Rorer Limited | Substituted azabicylic compounds and their use as inhibitors of the production of tnf and cyclic amp phosphodiesterase | 
        
          | GB9622363D0
              (en) | 1996-10-28 | 1997-01-08 | Celltech Therapeutics Ltd | Chemical compounds | 
        
          | JP2001507349A
              (ja)
            
            * | 1996-12-23 | 2001-06-05 | セルテック  セラピューティックス  リミテッド | 縮合多環式2−アミノピリミジン誘導体、それらの製造およびたんぱく質チロシンキナーゼ抑制因子としてのそれらの使用 | 
        
          | GB9705361D0
              (en)
            
            * | 1997-03-14 | 1997-04-30 | Celltech Therapeutics Ltd | Chemical compounds | 
        
          | US6022977A
              (en) | 1997-03-26 | 2000-02-08 | Dupont Pharmaceuticals Company | Dynamic resolution of isoxazoline thioesters to isoxazoline carboxylic acids | 
        
          | GB9713087D0
              (en)
            
            * | 1997-06-20 | 1997-08-27 | Celltech Therapeutics Ltd | Chemical compounds | 
        
          | DZ3019A1
              (fr)
            
            * | 1999-03-01 | 2005-05-20 | Smithkline Beecham Corp | Utilisation d'un inhibiteur de pde4 dans la préparation d'un médicament contre la copd. | 
        
          | GB9914258D0
              (en)
            
            * | 1999-06-18 | 1999-08-18 | Celltech Therapeutics Ltd | Chemical compounds | 
        
          | TR200201317T2
              (tr) | 1999-08-21 | 2002-11-21 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Sinerjistik kombinasyon. | 
        
          | KR100399361B1
              (ko) | 1999-11-04 | 2003-09-26 | 주식회사 엘지생명과학 | 캐스파제 억제제 함유 치료제 조성물 | 
        
          | AU7322300A
              (en)
            
            * | 1999-09-17 | 2001-04-24 | Lg Chem Investment Ltd. | Caspase inhibitor | 
        
          | GB9924862D0
              (en)
            
            * | 1999-10-20 | 1999-12-22 | Celltech Therapeutics Ltd | Chemical compounds | 
        
          | DE19953024A1
              (de)
            
            * | 1999-11-04 | 2001-05-10 | Merck Patent Gmbh | Isoxazolderivate als Phosphodiesterase VII-Hemmer | 
        
          | GB2362101A
              (en)
            
            * | 2000-05-12 | 2001-11-14 | Astrazeneca Ab | Treatment of chronic obstructive pulmonary disease | 
        
          | EP1389467B1
              (en) | 2001-05-23 | 2013-07-03 | Mitsubishi Tanabe Pharma Corporation | Therapeutic composition for the regenerative treatment of cartilage diseases | 
        
          | US20040146561A1
              (en)
            
            * | 2001-05-23 | 2004-07-29 | Naoki Sakurai | Compositions for promoting healing of bone fracture | 
        
          | RS94703A
              (en)
            
            * | 2001-05-29 | 2007-02-05 | Schering Aktiengesellschaft, | Cdk inhibiting pyrimidines, production thereof and their use as medicaments | 
        
          | CA2450589C
              (en) | 2001-06-08 | 2011-12-20 | Cytokine Pharmasciences, Inc. | Isoxazoline compounds having mif antagonist activity | 
        
          | US20030129186A1
              (en) | 2001-07-25 | 2003-07-10 | Biomarin Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport | 
        
          | AR039385A1
              (es)
            
            * | 2002-04-19 | 2005-02-16 | Astrazeneca Ab | Derivados de tioxantina como inhibidores de la mieloperoxidasa | 
        
          | WO2004043349A2
              (en)
            
            * | 2002-11-06 | 2004-05-27 | Bristol-Myers Squibb Company | Isoxazoline derivatives as inhibitors of matrix metalloproteinases and/or tnf-alpha converting enzyme | 
        
          | US7772188B2
              (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders | 
        
          | US7153824B2
              (en) | 2003-04-01 | 2006-12-26 | Applied Research Systems Ars Holding N.V. | Inhibitors of phosphodiesterases in infertility | 
        
          | KR100594544B1
              (ko)
            
            * | 2003-08-27 | 2006-06-30 | 주식회사  엘지생명과학 | 이소옥사졸린 구조를 갖는 캐스파제 저해제 | 
        
          | CA2537185A1
              (en) | 2003-08-29 | 2005-03-10 | Ranbaxy Laboratories Limited | Inhibitors of phosphodiesterase type-iv | 
        
          | SE0302756D0
              (sv)
            
            * | 2003-10-17 | 2003-10-17 | Astrazeneca Ab | Novel Compounds | 
        
          | EP1694655A2
              (en)
            
            * | 2003-11-26 | 2006-08-30 | Ranbaxy Laboratories Limited | Phosphodiesterase inhibitors | 
        
          | JP4883296B2
              (ja) | 2004-03-05 | 2012-02-22 | 日産化学工業株式会社 | イソキサゾリン置換ベンズアミド化合物及び有害生物防除剤 | 
        
          | WO2005094329A2
              (en)
            
            * | 2004-03-26 | 2005-10-13 | Cytokine Pharmasciences, Inc. | Compouns, compositions, processes of making, and methods of use related to inhibiting macrophage migration inhibitory factor | 
        
          | US20080009535A1
              (en)
            
            * | 2004-08-30 | 2008-01-10 | Sarala Balachandran | Inhibitors of phosphodiesterase type-IV | 
        
          | SE0402591D0
              (sv)
            
            * | 2004-10-25 | 2004-10-25 | Astrazeneca Ab | Novel use | 
        
          | MY140748A
              (en) | 2004-12-06 | 2010-01-15 | Astrazeneca Ab | Novel pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy | 
        
          | ES2370788T3
              (es)
            
            * | 2005-02-07 | 2011-12-22 | Aerocrine Ab | Controlar flujo de aliento exhalado durante análisis. | 
        
          | KR101324451B1
              (ko)
            
            * | 2005-03-15 | 2013-10-31 | 가니얼 이뮤노테라퓨틱스 인코포레이티드 | 면역 조절제 활성을 갖는 화합물 | 
        
          | EP3827747A1
              (en) | 2005-04-28 | 2021-06-02 | Otsuka Pharmaceutical Co., Ltd. | Pharma-informatics system | 
        
          | ES2351161T3
              (es)
            
            * | 2005-05-03 | 2011-02-01 | Ranbaxy Laboratories Limited | Inhibidores de la fosfodiesterasa a base de azol. | 
        
          | EP2258359A3
              (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin | 
        
          | US7678363B2
              (en) | 2005-08-26 | 2010-03-16 | Braincells Inc | Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs | 
        
          | CA2625153A1
              (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition | 
        
          | JP2009513672A
              (ja) | 2005-10-31 | 2009-04-02 | ブレインセルス,インコーポレイティド | 神経発生のgaba受容体媒介調節 | 
        
          | US20100216734A1
              (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents | 
        
          | CA2643199A1
              (en)
            
            * | 2006-03-08 | 2007-09-13 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents | 
        
          | US20100009983A1
              (en)
            
            * | 2006-05-09 | 2010-01-14 | Braincells, Inc. | 5 ht receptor mediated neurogenesis | 
        
          | JP2009536669A
              (ja) | 2006-05-09 | 2009-10-15 | ブレインセルス,インコーポレイティド | アンジオテンシン調節による神経新生 | 
        
          | JP2009536667A
              (ja)
            
            * | 2006-05-09 | 2009-10-15 | ブレインセルス,インコーポレイティド | 5ht受容体介在性の神経新生 | 
        
          | TW200804383A
              (en)
            
            * | 2006-06-05 | 2008-01-16 | Astrazeneca Ab | New compounds | 
        
          | AU2007292848A1
              (en)
            
            * | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative | 
        
          | US20100184806A1
              (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents | 
        
          | US20080103165A1
              (en)
            
            * | 2006-09-19 | 2008-05-01 | Braincells, Inc. | Ppar mediated modulation of neurogenesis | 
        
          | US20100029728A1
              (en)
            
            * | 2006-09-22 | 2010-02-04 | Ranbaxy Laboratories Limited | Phosphodiesterase inhibitors | 
        
          | US8795627B2
              (en) | 2007-03-21 | 2014-08-05 | Raptor Pharmaceuticals Inc. | Treatment of liver disorders by administration of RAP conjugates | 
        
          | CA2688161C
              (en) | 2007-06-04 | 2020-10-20 | Kunwar Shailubhai | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders | 
        
          | US20100120694A1
              (en) | 2008-06-04 | 2010-05-13 | Synergy Pharmaceuticals, Inc. | Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders | 
        
          | US8969514B2
              (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases | 
        
          | ES2624828T3
              (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros | 
        
          | PT3395372T
              (pt) | 2009-02-20 | 2022-05-05 | Enhanx Biopharm Inc | Sistema de entrega de medicamentos à base de glutationa | 
        
          | US20100216805A1
              (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations | 
        
          | KR101741629B1
              (ko) | 2009-05-06 | 2017-05-31 | 라보라토리 스킨 케어, 인크. | 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법 | 
        
          | US9616097B2
              (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use | 
        
          | US20120077778A1
              (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates | 
        
          | CN108676076A
              (zh) | 2011-03-01 | 2018-10-19 | 辛纳吉制药公司 | 制备鸟苷酸环化酶c激动剂的方法 | 
        
          | MX350825B
              (es) | 2011-03-31 | 2017-09-22 | Bayer Ip Gmbh | 3-fenilisoxazolin-5-carboxamidas y 3-fenilisoxazolin-5-tioamidas de accion herbicida y fungicida. | 
        
          | WO2013106547A1
              (en) | 2012-01-10 | 2013-07-18 | President And Fellows Of Harvard College | Beta-cell replication promoting compounds and methods of their use | 
        
          | ES2744245T3
              (es) | 2012-04-17 | 2020-02-24 | Geneone Life Science Inc | Compuestos que tienen actividad inmunomoduladora | 
        
          | EP2900645B1
              (de)
            
            * | 2012-09-25 | 2019-08-21 | Bayer CropScience AG | Herbizid wirksame 3-phenylisoxazolinderivate | 
        
          | US9850206B2
              (en) | 2012-11-20 | 2017-12-26 | Biogen Ma Inc. | S1P and/or ATX modulating agents | 
        
          | AU2014218599C1
              (en) | 2013-02-25 | 2018-09-06 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists for use in colonic cleansing | 
        
          | WO2014151200A2
              (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders | 
        
          | EP2970384A1
              (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses | 
        
          | AU2014274812B2
              (en) | 2013-06-05 | 2018-09-27 | Bausch Health Ireland Limited | Ultra-pure agonists of guanylate cyclase C, method of making and using same | 
        
          | CN103381157A
              (zh)
            
            * | 2013-07-04 | 2013-11-06 | 丁圣雨 | Chukrasone B在治疗慢性阻塞性肺疾病的药物中的应用 | 
        
          | KR20160042039A
              (ko) | 2013-08-09 | 2016-04-18 | 알데릭스, 인코포레이티드 | 인산염 수송을 억제하기 위한 화합물 및 방법 | 
        
          | ES2687393T3
              (es)
            
            * | 2014-04-22 | 2018-10-25 | Novartis Ag | Derivados del ácido hidroxámico de isoxazolina como inhibidores de LpxC | 
        
          | WO2018228986A1
              (de) | 2017-06-13 | 2018-12-20 | Bayer Aktiengesellschaft | Herbizid wirksame 3-phenylisoxazolin-5-carboxamide von tetrahydro- und dihydrofurancarbonsäureamiden | 
        
          | MX2019014980A
              (es) | 2017-06-13 | 2020-02-24 | Bayer Ag | 3-fenilisoxazolin-5-carboxamidas de acidos y esteres tetrahidro y dihidrofuranocarboxilicos con efecto herbicida. | 
        
          | ES2984279T3
              (es) | 2017-08-17 | 2024-10-29 | Bayer Ag | 3-fenil-5-trifluorometilisoxazolin-5-carboxamidas de ácidos y ésteres ciclopentilcarboxílicos con efecto herbicida | 
        
          | US12319664B2
              (en) | 2018-01-25 | 2025-06-03 | Bayer Aktiengesellschaft | Herbicidally active 3-phenylisoxazoline-5-carboxamides of cyclopentenylcarboxylic acid derivatives | 
        
          | JP7463393B2
              (ja) | 2019-03-12 | 2024-04-08 | バイエル・アクチエンゲゼルシヤフト | 除草活性のs含有シクロペンテニルカルボキシル酸エステルの3-フェニルイソオキサゾリン-5-カルボキサミド | 
        
          | EP3972599A1
              (en) | 2019-05-21 | 2022-03-30 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |