NO953976L - Deallyleringsreagens og fremgangsmåte for deallylering ved anvendelse av det nevnte reagens - Google Patents

Deallyleringsreagens og fremgangsmåte for deallylering ved anvendelse av det nevnte reagens

Info

Publication number
NO953976L
NO953976L NO953976A NO953976A NO953976L NO 953976 L NO953976 L NO 953976L NO 953976 A NO953976 A NO 953976A NO 953976 A NO953976 A NO 953976A NO 953976 L NO953976 L NO 953976L
Authority
NO
Norway
Prior art keywords
reagent
pct
deallylation
solvent system
sec
Prior art date
Application number
NO953976A
Other languages
English (en)
Norwegian (no)
Other versions
NO953976D0 (no
Inventor
Jean-Marie Bernard
Errol Blart
Jean-Pierre Genet
Sandrine Lemaire-Audoire
Monique Savignac
Original Assignee
Rhone Poulenc Chimie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Chimie filed Critical Rhone Poulenc Chimie
Publication of NO953976D0 publication Critical patent/NO953976D0/no
Publication of NO953976L publication Critical patent/NO953976L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/40Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
    • B01J23/44Palladium
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/62Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/52Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Lining Or Joining Of Plastics Or The Like (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Catalysts (AREA)
NO953976A 1993-04-09 1995-10-06 Deallyleringsreagens og fremgangsmåte for deallylering ved anvendelse av det nevnte reagens NO953976L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9304233A FR2703688B1 (fr) 1993-04-09 1993-04-09 Réactif de désallylation, procédé de désallylation utilisant ledit réactif.
PCT/FR1994/000397 WO1994024088A1 (fr) 1993-04-09 1994-04-08 Reactif de desallylation, procede de desallylation utilisant ce reactif

Publications (2)

Publication Number Publication Date
NO953976D0 NO953976D0 (no) 1995-10-06
NO953976L true NO953976L (no) 1995-12-08

Family

ID=9445928

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953976A NO953976L (no) 1993-04-09 1995-10-06 Deallyleringsreagens og fremgangsmåte for deallylering ved anvendelse av det nevnte reagens

Country Status (16)

Country Link
US (1) US5773617A (de)
EP (1) EP0693052B1 (de)
JP (1) JP3657605B2 (de)
KR (1) KR100340613B1 (de)
CN (1) CN1160308C (de)
AT (1) ATE211725T1 (de)
AU (1) AU697811B2 (de)
BR (1) BR9406137A (de)
CA (1) CA2160163A1 (de)
DE (1) DE69429616T2 (de)
ES (1) ES2166372T3 (de)
FI (1) FI954765A (de)
FR (1) FR2703688B1 (de)
HU (1) HU218397B (de)
NO (1) NO953976L (de)
WO (1) WO1994024088A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1044962A4 (de) * 1997-11-11 2004-03-24 Chisso Corp Methode zur katalytischen abspaltung einer schutzgruppe mit allylfunktion
WO2006040182A1 (en) 2004-10-14 2006-04-20 Abbott Gmbh & Co. Kg Heterocyclic compounds suitable for treating disorders that respond to modulation of the dopamine d3 receptor
EP1809597B1 (de) 2004-10-14 2012-01-11 Abbott GmbH & Co. KG Zur behandlung von erkrankungen, die auf eine modulation des dopamin-d3-rezeptors ansprechen, geeignete aminoethylaromatische verbindungen
MX2007004355A (es) 2004-10-14 2007-07-17 Abbot Gmbh & Co Kg Compuestos de 6-amino (aza) indano adecuados para tratar trastornos que responden a la modulacion del receptor de dopamina d3.
DK2638001T3 (da) * 2010-11-12 2014-09-22 Bayer Ip Gmbh Fremgangsmåde til fremstilling af 1,2-difluorethylamin gående ud fra prop-2-en-1-amin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3688942T2 (de) * 1985-03-06 1994-02-24 Nippon Zeon Co Verfahren zur Herstellung von Oximderivaten.
JPH0662471B2 (ja) * 1985-09-20 1994-08-17 三井石油化学工業株式会社 2,6−ジヒドロキシナフタレンの製造方法
JPS6270392A (ja) * 1985-09-25 1987-03-31 Nippon Zeon Co Ltd オリゴヌクレオチド化合物の製造法
FR2652514A1 (fr) * 1989-06-22 1991-04-05 Rhone Poulenc Sante Nouveau catalyseur a base de palladium et son emploi.
FR2675804B1 (fr) * 1991-04-25 1995-04-07 Propeptide Sa Procede de synthese de peptides, nouveaux derives d'acides amines mis en óoeuvre dans ce procede et leurs procedes de preparation.
EP0518295A3 (en) * 1991-06-14 1993-09-01 Millipore Corporation Allyl side chain protection in peptide synthesis
FR2690153A1 (fr) * 1992-04-15 1993-10-22 Rhone Poulenc Chimie Réactif et procédé catalytique utile pour cliver une fonction protégée.

Also Published As

Publication number Publication date
FI954765A0 (fi) 1995-10-06
CN1122594A (zh) 1996-05-15
FR2703688B1 (fr) 1995-05-19
HU218397B (hu) 2000-08-28
AU6541094A (en) 1994-11-08
DE69429616T2 (de) 2002-08-14
JP3657605B2 (ja) 2005-06-08
FR2703688A1 (fr) 1994-10-14
HUT76715A (en) 1997-10-28
AU697811B2 (en) 1998-10-15
US5773617A (en) 1998-06-30
BR9406137A (pt) 1996-02-27
ES2166372T3 (es) 2002-04-16
WO1994024088A1 (fr) 1994-10-27
KR100340613B1 (ko) 2003-02-11
FI954765A (fi) 1995-12-05
HU9502942D0 (en) 1995-12-28
EP0693052B1 (de) 2002-01-09
ATE211725T1 (de) 2002-01-15
CA2160163A1 (fr) 1994-10-27
DE69429616D1 (de) 2002-02-14
EP0693052A1 (de) 1996-01-24
CN1160308C (zh) 2004-08-04
JPH08508986A (ja) 1996-09-24
NO953976D0 (no) 1995-10-06

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