NO953925L - MSRV1-virus og MSRV2-patogent og/eller infeksiöst middel forbundet med multippel sklerose, nukleinsyrekomponenter og anvendelse av disse - Google Patents
MSRV1-virus og MSRV2-patogent og/eller infeksiöst middel forbundet med multippel sklerose, nukleinsyrekomponenter og anvendelse av disseInfo
- Publication number
- NO953925L NO953925L NO953925A NO953925A NO953925L NO 953925 L NO953925 L NO 953925L NO 953925 A NO953925 A NO 953925A NO 953925 A NO953925 A NO 953925A NO 953925 L NO953925 L NO 953925L
- Authority
- NO
- Norway
- Prior art keywords
- pathogenic
- virus
- multiple sclerosis
- msrv1
- msrv2
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/912—Absidia
Abstract
Preparat som inneholder to patogene og/eller infeksiøse midler forbundet med multippel sklerose, nem- lig et første middel som består av et humant virus med reverstranskriptaseak- tivitet og beslektet med en familie av endogene, retrovirale elementer, eller en variant av dette virus, og et andre middel, eller en variant av dette andre middel, hvor de to patogene og/eller infeksiøse midler stammer fra samme virusstamme valgt blant stammene beteg- net POL-2, deponert ved ECACC 22. juli 1992 under deponeringsbetegnelsen V92072202, henholdsvis MS7PG, deponert ved ECACC 8. januar 1993 under deponer- ingsbetegnelsen V93010816, og fra deres variantstammer.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9401532A FR2715937A1 (fr) | 1994-02-04 | 1994-02-04 | Virus MSRV1 et MSRV2 associés ensemble à la sclérose en plaques et leurs constituants nucléiques. |
FR9401529A FR2715936B1 (fr) | 1994-02-04 | 1994-02-04 | Virus MSRV1 associé à la sclérose en plaques, et ses constituants nucléiques. |
FR9401531A FR2715939B1 (fr) | 1994-02-04 | 1994-02-04 | Virus MSRV2 associé à la sclérose en plaques, et ses constituants nucléiques. |
FR9401530A FR2715938B1 (fr) | 1994-02-04 | 1994-02-04 | Constituants nucléiques du virus MSRV1, associé à la sclérose en plaques. |
FR9414322A FR2727428B1 (fr) | 1994-11-24 | 1994-11-24 | Virus msrv1 associe a la sclerose en plaques et ses constituants nucleiques |
FR9415810A FR2728585A1 (fr) | 1994-12-23 | 1994-12-23 | Virus msrv1 et agent pathogene et/ou infectant msrv2 associes a la sclerose en plaques et leurs constituants nucleiques |
PCT/FR1995/000142 WO1995021256A1 (fr) | 1994-02-04 | 1995-02-06 | Virus msrv1 et agent pathogene et/ou infectant msrv2 associes a la sclerose en plaques, leurs constituants nucleiques et leurs applications |
Publications (2)
Publication Number | Publication Date |
---|---|
NO953925D0 NO953925D0 (no) | 1995-10-03 |
NO953925L true NO953925L (no) | 1995-12-04 |
Family
ID=27546415
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO953925A NO953925L (no) | 1994-02-04 | 1995-10-03 | MSRV1-virus og MSRV2-patogent og/eller infeksiöst middel forbundet med multippel sklerose, nukleinsyrekomponenter og anvendelse av disse |
Country Status (12)
Country | Link |
---|---|
US (6) | US5871996A (no) |
EP (1) | EP0674004B1 (no) |
JP (1) | JP3611856B2 (no) |
AT (1) | ATE285475T1 (no) |
AU (1) | AU704440B2 (no) |
CA (1) | CA2141907A1 (no) |
DE (2) | DE674004T1 (no) |
ES (1) | ES2233936T3 (no) |
FI (1) | FI954699A (no) |
NO (1) | NO953925L (no) |
NZ (1) | NZ279855A (no) |
WO (1) | WO1995021256A1 (no) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3611856B2 (ja) | 1994-02-04 | 2005-01-19 | ベーイーオー・メリュー | 多発性硬化症に関与するmsrv1ウイルスおよびmsrv2病因性及び/又は感染性の作因、核酸成分およびその応用 |
FR2731356B1 (fr) * | 1995-03-09 | 1997-04-30 | Bio Merieux | Virus msrv-1 et agent pathogene et/ou infectant msrv-2 associes a la polyarthrite rhumatoide |
FR2737500B1 (fr) | 1995-08-03 | 1997-08-29 | Bio Merieux | Materiel viral et fragments nucleotidiques associes a la sclerose en plaques, a des fins de diagnostic, prophylactiques et therapeutiques |
US6771381B1 (en) | 1998-11-13 | 2004-08-03 | Laurence C. Klein | Distributed computer architecture and process for virtual copying |
CA2272845C (en) | 1996-11-26 | 2010-01-12 | Bio Merieux | Viral material and nucleotide fragments associated with multiple sclerosis, for diagnostic, prophylactic and therapeutic purposes |
EP0887070B1 (en) * | 1997-05-30 | 2004-12-22 | Kibun Food ChemiFA Co., Ltd. | External composition for skin comprising sphingoglycolipid |
FR2765588A1 (fr) | 1997-07-07 | 1999-01-08 | Bio Merieux | Materiel nucleique retroviral et fragments nucleotidiques notamment associes a la sclerose en plaques et/ou la polyarthrite rhumatoide, a des fins de diagnostic, prophylactiques et therapeutiques |
US20070067859A1 (en) * | 1997-07-14 | 2007-03-22 | Michel Georges | Double-muscling in mammals |
DE69841139D1 (de) * | 1997-07-14 | 2009-10-22 | Univ Liege | Mutationen im myostatingen steigern muskelmasse in säugetieren |
US6103466A (en) * | 1997-07-14 | 2000-08-15 | University Of Liege | Double-muscling in mammals |
JP2002511277A (ja) * | 1998-04-08 | 2002-04-16 | エムエス・リサーチ・アクティーゼルスカブ | 多発性硬化症および他の脱髄性疾患の診断 |
FR2780069B1 (fr) * | 1998-06-23 | 2002-06-28 | Inst Nat Sante Rech Med | Famille de sequences nucleiques et de sequences proteiques deduites presentant des motifs retroviraux endogenes humains et leurs applications |
FR2788784A1 (fr) * | 1999-01-21 | 2000-07-28 | Bio Merieux | Fragment nucleique endogene associe a une maladie auto-immune, procede de marquage et reactif |
EP1029917A1 (en) * | 1999-02-15 | 2000-08-23 | Bio Merieux | The LTR region of MSRV-1 and the proteins it encodes, and probes and methods for detecting MSRV-1 retrovirus |
US6787303B1 (en) | 1999-04-01 | 2004-09-07 | Alton Ochsner Medical Foundation | Identification of a novel retrovirus associated with primary sclerosing cholangitis and autoimmune hepatitis |
AU4187400A (en) * | 1999-04-01 | 2000-10-23 | Alton Ochsner Medical Foundation | Retrovirus associated with primary sclerosing cholangitis |
DE19921419A1 (de) * | 1999-05-08 | 2000-11-16 | Univ Ruprecht Karls Heidelberg | Verfahren zum spezifischen Nachweis und zur Identifizierung retroviraler Nukleinsäuren / Retroviren in einem Untersuchungsgut |
EP1409544B1 (en) * | 2001-07-03 | 2009-06-17 | Genentech, Inc. | Human dr4 antibodies and uses thereof |
WO2003016546A1 (en) * | 2001-08-21 | 2003-02-27 | Flinders Technologies Pty Ltd. | Method and device for simultaneously molecularly cloning and polylocus profiling of genomes or genome mixtures |
FR2865403B1 (fr) * | 2004-01-23 | 2009-06-12 | Biomerieux Sa | Composition pour le traitement d'une pathologie associee a la msrv/herv-w |
KR101235479B1 (ko) | 2004-08-06 | 2013-02-20 | 제넨테크, 인크. | 바이오마커를 사용한 분석 및 방법 |
CN102978277A (zh) * | 2004-08-06 | 2013-03-20 | 健泰科生物技术公司 | 使用生物标志的测定法和方法 |
CN101048428A (zh) * | 2004-09-08 | 2007-10-03 | 健泰科生物技术公司 | 利用死亡受体配体和cd20抗体的方法 |
MX2007002855A (es) * | 2004-09-08 | 2007-04-27 | Genentech Inc | Metodos para usar ligandos de receptor de muerte y anticuerpos cd20. |
JO3000B1 (ar) * | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
US8029783B2 (en) * | 2005-02-02 | 2011-10-04 | Genentech, Inc. | DR5 antibodies and articles of manufacture containing same |
CA2619759A1 (en) * | 2005-08-16 | 2007-02-22 | Genentech, Inc. | Apoptosis sensitivity to ap02l/trail by testing for galnac-t14 expression in cells/tissues |
WO2010030931A1 (en) * | 2008-09-11 | 2010-03-18 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Oligonucleotides targeting human endogenous retrovirus 9 (erv-9) long terminal repeat (ltr) and methods of use |
JP2014513128A (ja) | 2011-05-03 | 2014-05-29 | ジェネンテック, インコーポレイテッド | 血管破壊剤とその使用 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1133829A (en) * | 1978-08-24 | 1982-10-19 | Neil J.L. Gilmour | Pasteurellosis vaccines |
US4311686A (en) * | 1979-04-30 | 1982-01-19 | The Immunology Development Corporation | Methodology for the immunodiagnosis of multiple sclerosis and/or malignant diseases from blood sample analysis |
US4396600A (en) * | 1980-12-18 | 1983-08-02 | Gus Gallucci | Adult schistosome worm-derived antigenic substance and method of obtaining same |
US4388298A (en) * | 1982-07-14 | 1983-06-14 | The United States Of America As Represented By The Secretary Of Agriculture | Propagation of hemorrhagic enteritis virus in a turkey cell line and vaccine produced |
GB8324800D0 (en) * | 1983-09-15 | 1983-10-19 | Pasteur Institut | Antigens |
US4647773A (en) * | 1984-04-23 | 1987-03-03 | The United States Of America As Represented By The Department Of Health And Human Services | Method of continuous production of retroviruses (HTLV-III) from patients with AIDS and pre-AIDS |
US4520113A (en) * | 1984-04-23 | 1985-05-28 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Serological detection of antibodies to HTLV-III in sera of patients with AIDS and pre-AIDS conditions |
NZ218050A (en) * | 1985-11-13 | 1989-05-29 | Wistar Inst | Test for the presence of htlv-1v |
US4900553A (en) * | 1987-09-11 | 1990-02-13 | Case Western Reserve University | Method of reducing glial scar formation and promoting axon and blood vessel growth and/or regeneration through the use of activated immature astrocytes |
EP0326395A2 (en) * | 1988-01-29 | 1989-08-02 | City Of Hope | Method of detecting and identifying certain viral sequences |
FR2651581B1 (fr) * | 1989-09-06 | 1994-05-13 | Centre Nal Recherc Scientifique | Moyens pour le diagnostic de neuropathies demyelinisantes, en particulier de la sclerose en plaques. |
US5219837A (en) * | 1990-06-21 | 1993-06-15 | Trustees Of The University Of Pennsylvania | Method of stimulating myelination of cells |
US5158976A (en) * | 1990-10-29 | 1992-10-27 | The Children's Medical Center Corporation | Controlling glutamine/glutamate related neuronal injury |
DK173091D0 (da) * | 1991-10-11 | 1991-10-11 | Schleroseforeningen The Danish | Biologisk materiale |
FR2689520B1 (fr) * | 1992-04-03 | 1996-07-19 | Bio Merieux | Procede et milieu de culture pour l'obtention de cellules infectees par un virus associe a la sclerose en plaques. |
FR2689521B1 (fr) * | 1992-04-03 | 1996-07-19 | Bio Merieux | Procede d'obtention et maintien d'une culture cellulaire viable, infectee par un virus associe a la sclerose en plaques, et produits biologiques derives de ladite culture. |
EP0642585B1 (en) * | 1992-05-18 | 2005-12-28 | Genentech, Inc. | Activation of oligomerizing receptors by using fused receptor ligands |
GB9310657D0 (en) * | 1993-05-24 | 1993-07-07 | Univ London | Retrovirus |
JP3611856B2 (ja) | 1994-02-04 | 2005-01-19 | ベーイーオー・メリュー | 多発性硬化症に関与するmsrv1ウイルスおよびmsrv2病因性及び/又は感染性の作因、核酸成分およびその応用 |
FR2716198B1 (fr) | 1994-02-15 | 1996-04-19 | Bio Merieux | Facteur cytotoxique tel qu'associé à la sclérose en plaques, sa détection et sa quantification. |
-
1995
- 1995-02-06 JP JP52042695A patent/JP3611856B2/ja not_active Expired - Lifetime
- 1995-02-06 CA CA002141907A patent/CA2141907A1/fr not_active Abandoned
- 1995-02-06 AT AT95420027T patent/ATE285475T1/de not_active IP Right Cessation
- 1995-02-06 ES ES95420027T patent/ES2233936T3/es not_active Expired - Lifetime
- 1995-02-06 DE DE0674004T patent/DE674004T1/de active Pending
- 1995-02-06 NZ NZ279855A patent/NZ279855A/en unknown
- 1995-02-06 AU AU17114/95A patent/AU704440B2/en not_active Ceased
- 1995-02-06 DE DE69533863T patent/DE69533863T2/de not_active Expired - Lifetime
- 1995-02-06 US US08/384,137 patent/US5871996A/en not_active Expired - Lifetime
- 1995-02-06 EP EP95420027A patent/EP0674004B1/fr not_active Expired - Lifetime
- 1995-02-06 WO PCT/FR1995/000142 patent/WO1995021256A1/fr active Application Filing
- 1995-06-06 US US08/471,724 patent/US5800980A/en not_active Expired - Lifetime
- 1995-06-06 US US08/471,969 patent/US5871745A/en not_active Expired - Lifetime
- 1995-06-06 US US08/470,006 patent/US5962217A/en not_active Expired - Lifetime
- 1995-10-03 NO NO953925A patent/NO953925L/no not_active Application Discontinuation
- 1995-10-03 FI FI954699A patent/FI954699A/fi unknown
-
1998
- 1998-08-13 US US09/133,411 patent/US6342383B1/en not_active Expired - Lifetime
- 1998-11-30 US US09/200,990 patent/US6184025B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US6342383B1 (en) | 2002-01-29 |
EP0674004B1 (fr) | 2004-12-22 |
CA2141907A1 (fr) | 1995-08-05 |
US6184025B1 (en) | 2001-02-06 |
AU704440B2 (en) | 1999-04-22 |
WO1995021256A1 (fr) | 1995-08-10 |
JP3611856B2 (ja) | 2005-01-19 |
ES2233936T3 (es) | 2005-06-16 |
FI954699A0 (fi) | 1995-10-03 |
FI954699A (fi) | 1995-10-03 |
US5800980A (en) | 1998-09-01 |
NZ279855A (en) | 1998-05-27 |
ATE285475T1 (de) | 2005-01-15 |
DE674004T1 (de) | 1996-09-19 |
AU1711495A (en) | 1995-08-21 |
US5871996A (en) | 1999-02-16 |
DE69533863D1 (de) | 2005-01-27 |
JPH08511170A (ja) | 1996-11-26 |
US5962217A (en) | 1999-10-05 |
NO953925D0 (no) | 1995-10-03 |
EP0674004A1 (fr) | 1995-09-27 |
US5871745A (en) | 1999-02-16 |
DE69533863T2 (de) | 2006-02-16 |
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