NO953883L - Rensing av faktor VII - Google Patents

Rensing av faktor VII

Info

Publication number
NO953883L
NO953883L NO953883A NO953883A NO953883L NO 953883 L NO953883 L NO 953883L NO 953883 A NO953883 A NO 953883A NO 953883 A NO953883 A NO 953883A NO 953883 L NO953883 L NO 953883L
Authority
NO
Norway
Prior art keywords
purification
factor vii
purification steps
fvi1
degradation
Prior art date
Application number
NO953883A
Other languages
English (en)
Norwegian (no)
Other versions
NO953883D0 (no
Inventor
Tony Joergensen
Anders H Pedersen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO953883D0 publication Critical patent/NO953883D0/no
Publication of NO953883L publication Critical patent/NO953883L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6437—Coagulation factor VIIa (3.4.21.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21021—Coagulation factor VIIa (3.4.21.21)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Catalysts (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO953883A 1993-03-31 1995-09-29 Rensing av faktor VII NO953883L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK93382A DK38293D0 (da) 1993-03-31 1993-03-31 Fremstilling af proteiner
PCT/DK1994/000122 WO1994022905A1 (en) 1993-03-31 1994-03-24 Purification of factor vii

Publications (2)

Publication Number Publication Date
NO953883D0 NO953883D0 (no) 1995-09-29
NO953883L true NO953883L (no) 1995-11-28

Family

ID=8092871

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953883A NO953883L (no) 1993-03-31 1995-09-29 Rensing av faktor VII

Country Status (16)

Country Link
US (1) US5700914A (da)
EP (1) EP0691984A1 (da)
JP (1) JPH08508264A (da)
CN (1) CN1039231C (da)
AU (1) AU677309B2 (da)
CA (1) CA2159313A1 (da)
CZ (1) CZ253395A3 (da)
DK (1) DK38293D0 (da)
FI (1) FI954649A7 (da)
HU (1) HUT72712A (da)
IL (1) IL109164A0 (da)
NO (1) NO953883L (da)
PL (1) PL310887A1 (da)
TW (1) TW278079B (da)
WO (1) WO1994022905A1 (da)
ZA (1) ZA941956B (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19538716A1 (de) * 1995-10-18 1997-04-24 Behringwerke Ag Verfahren zur Quantifizierung von aktiviertem Gerinnungsfaktor VII (FVIIa)
DE19538715A1 (de) 1995-10-18 1997-04-30 Behringwerke Ag Verfahren zur Reinigung von Faktor VII und aktiviertem Faktor VII
KR20010043323A (ko) 1998-05-06 2001-05-25 제넨테크, 인크. 이온 교환 크로마토그래피에 의한 단백질 정제 방법
AT408613B (de) 1998-06-17 2002-01-25 Immuno Ag Pharmazeutisches faktor vii-präparat
PL206148B1 (pl) 2000-02-11 2010-07-30 Bayer HealthCare LLCBayer HealthCare LLC Koniugat polipeptydowy, polipeptyd, sekwencja nukleotydowa, wektor ekspresyjny, komórka gospodarz, sposób wytwarzania koniugatu polipeptydowego, środek farmaceutyczny i zastosowanie koniugatu polipeptydowego
CN1607958A (zh) 2001-12-21 2005-04-20 诺和诺德医疗保健公司 因子ⅶ多肽的液体组合物
US20040009918A1 (en) * 2002-05-03 2004-01-15 Hanne Nedergaard Stabilised solid compositions of modified factor VII
BRPI0311959B8 (pt) 2002-06-21 2021-05-25 Novo Nordisk Healthcare Ag composição, métodos para preparar um polipeptídeo estável do fator vii, e para tratar uma síndrome responsiva do fator vii, e, uso do polipeptídeo do fator vii
RU2364626C2 (ru) * 2003-03-18 2009-08-20 Ново Нордиск Хелт Кэр Аг Способ получения, способ очистки и способ стабилизации полипептидов фактора vii, ix и x
US7897734B2 (en) 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
MXPA05012476A (es) * 2003-05-23 2006-02-22 Novo Nordisk Healthcare Ag Estabilizacion de proteina en solucion.
EP1641487B1 (en) * 2003-06-25 2012-02-29 Novo Nordisk Health Care AG Liquid composition of factor vii polypeptides
JP5306597B2 (ja) * 2003-07-01 2013-10-02 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 第ｖｉｉ因子ポリペプチドの液体水性薬学的組成物
CN102872451A (zh) 2003-08-14 2013-01-16 诺和诺德医疗保健公司 因子vii多肽类的含水液体药物组合物
CN1890257A (zh) 2003-12-01 2007-01-03 诺和诺德医疗保健公司 液体因子ⅶ组合物的病毒过滤
KR20140093711A (ko) * 2003-12-19 2014-07-28 노보 노르디스크 헬스 케어 악티엔게젤샤프트 인자 ｖｉｉ 폴리펩티드의 안정화된 조성물
EP2360171A1 (en) * 2004-12-23 2011-08-24 Novo Nordisk Health Care AG Reduction of the content of protein contaminants in compositions comprising a vitamin K-dependent protein of interest
EP1841863B1 (en) * 2005-01-14 2010-08-04 Bayer HealthCare LLC Method for purification of factor vii
DK1907540T3 (da) * 2005-07-22 2013-03-11 Bayer Healthcare Llc Aktivering af faktor VII i opløsning
US20130172274A1 (en) 2005-12-20 2013-07-04 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
US8334257B2 (en) * 2005-12-20 2012-12-18 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
US8841255B2 (en) 2005-12-20 2014-09-23 Duke University Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
CA2726894A1 (en) 2008-06-27 2009-12-30 Duke University Therapeutic agents comprising elastin-like peptides
CN103539852B (zh) * 2012-07-12 2015-08-12 上海泰龙生物医药科技有限公司 一种从细胞培养液中分离纯化重组人凝血八因子的方法
EP2687595B1 (en) 2012-07-19 2018-05-30 Laboratoire Français du Fractionnement et des Biotechnologies Method for purifying transgenic factor VII
BR112015008666B1 (pt) 2012-10-17 2020-04-07 Procter & Gamble produto extensível para tratamento dental e método de aplicação de um ativo para tratamento bucal
WO2018117143A1 (ja) * 2016-12-22 2018-06-28 一般財団法人化学及血清療法研究所 血液凝固第ｖｉｉ因子の高収率回収のためのクロマトグラフィー法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4981952A (en) * 1988-10-04 1991-01-01 Eli Lilly And Company Method for the purification of vitamin K-dependent proteins

Also Published As

Publication number Publication date
EP0691984A1 (en) 1996-01-17
PL310887A1 (en) 1996-01-08
AU6423994A (en) 1994-10-24
CA2159313A1 (en) 1994-10-13
TW278079B (da) 1996-06-11
WO1994022905A1 (en) 1994-10-13
CN1121723A (zh) 1996-05-01
CN1039231C (zh) 1998-07-22
FI954649A0 (fi) 1995-09-29
AU677309B2 (en) 1997-04-17
HU9502846D0 (en) 1995-12-28
US5700914A (en) 1997-12-23
IL109164A0 (en) 1994-06-24
JPH08508264A (ja) 1996-09-03
FI954649L (fi) 1995-09-29
HUT72712A (en) 1996-05-28
CZ253395A3 (en) 1996-01-17
DK38293D0 (da) 1993-03-31
FI954649A7 (fi) 1995-09-29
NO953883D0 (no) 1995-09-29
ZA941956B (en) 1994-09-30

Similar Documents

Publication Publication Date Title
NO953883L (no) Rensing av faktor VII
GB2270030B (en) Method of producing fibre or film
DE69426278D1 (de) Kontinuierliche Herstellung eines Schlammes mit mehreren Komponenten
PL310550A1 (en) Fibre treating method
AU6430794A (en) A method of treating endo-osteal materials
ZA945657B (en) Method to inhibit restenosis
DE69433617D1 (de) Intraluminales transplantat
FI944443A0 (fi) Menetelmä kaasun syöttämiseksi nesteeseen
DE69433831D1 (de) Modifizierung von Pertussistoxin
DE69329844D1 (de) Beschichtungsverfahren
FI932871L (fi) Stereoselektiv anjonglykosylationsprocess
DE69318527D1 (de) Entwicklungsverfahren
DE69406974D1 (de) Beschichtungsverfahren
AU7687891A (en) Method for treating mechanical pulp plant effluent
NO810367L (no) Midler og prosess for beskyttelse av tre og belegg mot mikroorganismer.
FR2708210B1 (fr) Procédé de traitement d'un milieu poreux obstrué.
FI933530L (fi) Anordning foer tvinning av tvinningselement i vaexlande riktning
TW288066B (da)
AU7318691A (en) A method of treating a mammal with a biologically active compound
DE69408925D1 (de) Beschichtungsverfahren
FI945440L (fi) Prosessilaitos
FR2687403B1 (fr) Procede de fabrication d'un ester d'un compose organosilane et utilisation.
DK0587480T3 (da) Deponeringsindretning
EP0752856A4 (en) METHOD FOR TREATING HYPERLIPIDEMIA
AU7237491A (en) A method of treating a mammal with a biologically active compound