FI954649A0 - Hyytymistekijä VII:n puhdistus - Google Patents

Hyytymistekijä VII:n puhdistus

Info

Publication number
FI954649A0
FI954649A0 FI954649A FI954649A FI954649A0 FI 954649 A0 FI954649 A0 FI 954649A0 FI 954649 A FI954649 A FI 954649A FI 954649 A FI954649 A FI 954649A FI 954649 A0 FI954649 A0 FI 954649A0
Authority
FI
Finland
Prior art keywords
purification
factor vii
vii
factor
Prior art date
Application number
FI954649A
Other languages
English (en)
Swedish (sv)
Other versions
FI954649A (fi
Inventor
Tony Joergensen
Anders H Pedersen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of FI954649A publication Critical patent/FI954649A/fi
Publication of FI954649A0 publication Critical patent/FI954649A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6437—Coagulation factor VIIa (3.4.21.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21021—Coagulation factor VIIa (3.4.21.21)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Catalysts (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
FI954649A 1993-03-31 1995-09-29 Hyytymistekijä VII:n puhdistus FI954649A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK93382A DK38293D0 (da) 1993-03-31 1993-03-31 Fremstilling af proteiner
PCT/DK1994/000122 WO1994022905A1 (en) 1993-03-31 1994-03-24 Purification of factor vii

Publications (2)

Publication Number Publication Date
FI954649A FI954649A (fi) 1995-09-29
FI954649A0 true FI954649A0 (fi) 1995-09-29

Family

ID=8092871

Family Applications (1)

Application Number Title Priority Date Filing Date
FI954649A FI954649A0 (fi) 1993-03-31 1995-09-29 Hyytymistekijä VII:n puhdistus

Country Status (16)

Country Link
US (1) US5700914A (fi)
EP (1) EP0691984A1 (fi)
JP (1) JPH08508264A (fi)
CN (1) CN1039231C (fi)
AU (1) AU677309B2 (fi)
CA (1) CA2159313A1 (fi)
CZ (1) CZ253395A3 (fi)
DK (1) DK38293D0 (fi)
FI (1) FI954649A0 (fi)
HU (1) HUT72712A (fi)
IL (1) IL109164A0 (fi)
NO (1) NO953883L (fi)
PL (1) PL310887A1 (fi)
TW (1) TW278079B (fi)
WO (1) WO1994022905A1 (fi)
ZA (1) ZA941956B (fi)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19538716A1 (de) * 1995-10-18 1997-04-24 Behringwerke Ag Verfahren zur Quantifizierung von aktiviertem Gerinnungsfaktor VII (FVIIa)
DE19538715A1 (de) 1995-10-18 1997-04-30 Behringwerke Ag Verfahren zur Reinigung von Faktor VII und aktiviertem Faktor VII
WO1999057134A1 (en) 1998-05-06 1999-11-11 Genentech, Inc. Protein purification by ion exchange chromatography
AT408613B (de) * 1998-06-17 2002-01-25 Immuno Ag Pharmazeutisches faktor vii-präparat
AU783512B2 (en) 2000-02-11 2005-11-03 Bayer Healthcare Llc Factor VII or VIIa-like molecules
BR0215216A (pt) * 2001-12-21 2004-11-16 Novo Nordisk Healthcare Ag Composição aquosa lìquida, método para preparar uma composição aquosa lìquida de um polipeptìdeo de fator vii, uso de uma composição aquosa lìquida, e, método para o tratamento de uma sìndrome de resposta ao fator vii
US20040009918A1 (en) * 2002-05-03 2004-01-15 Hanne Nedergaard Stabilised solid compositions of modified factor VII
BRPI0311959B8 (pt) 2002-06-21 2021-05-25 Novo Nordisk Healthcare Ag composição, métodos para preparar um polipeptídeo estável do fator vii, e para tratar uma síndrome responsiva do fator vii, e, uso do polipeptídeo do fator vii
EP3103869A1 (en) 2003-03-18 2016-12-14 Novo Nordisk Health Care AG Method for the production of factor vii polypeptides
US7897734B2 (en) 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
KR20060015574A (ko) * 2003-05-23 2006-02-17 노보 노르디스크 헬스 케어 악티엔게젤샤프트 용액 중 단백질 안정화
WO2004112828A1 (en) 2003-06-25 2004-12-29 Novo Nordisk Health Care Ag Liquid composition of factor vii polypeptides
WO2005002615A1 (en) * 2003-07-01 2005-01-13 Novo Nordisk Health Care Ag Liquid, aqueous pharmaceutical composition of factor vii polypeptides
CN102872451A (zh) 2003-08-14 2013-01-16 诺和诺德医疗保健公司 因子vii多肽类的含水液体药物组合物
BRPI0416950B8 (pt) 2003-12-01 2021-05-25 Novo Nordisk Healthcare Ag métodos para remover vírus de uma composição do fator vii líquida, para inativar vírus em uma composição do fator vii líquida, e para eliminar em alto nível a presença de vírus ativos em uma composição do fator vii líquida.
KR20150138427A (ko) * 2003-12-19 2015-12-09 노보 노르디스크 헬스 케어 악티엔게젤샤프트 인자 ｖｉｉ 폴리펩티드의 안정화된 조성물
EP1831242B1 (en) * 2004-12-23 2012-09-26 Novo Nordisk Health Care AG Reduction of the content of protein contaminants in compositions comprising a vitamin k-dependent protein of interest
US20090047723A1 (en) * 2005-01-14 2009-02-19 Bayer Healthcare Llc Method for purification of factor vii
PT1907540E (pt) * 2005-07-22 2013-02-04 Bayer Healthcare Llc Activação do factor vii em solução
US8841255B2 (en) 2005-12-20 2014-09-23 Duke University Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
US20130172274A1 (en) 2005-12-20 2013-07-04 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
CN101384272B (zh) * 2005-12-20 2013-05-01 杜克大学 用于递送具有增强的药理性质的活性剂的方法和组合物
CN105727261A (zh) 2008-06-27 2016-07-06 杜克大学 包含弹性蛋白样肽的治疗剂
CN103539852B (zh) * 2012-07-12 2015-08-12 上海泰龙生物医药科技有限公司 一种从细胞培养液中分离纯化重组人凝血八因子的方法
EP2687595B1 (en) * 2012-07-19 2018-05-30 Laboratoire Français du Fractionnement et des Biotechnologies Method for purifying transgenic factor VII
US10285915B2 (en) 2012-10-17 2019-05-14 The Procter & Gamble Company Strip for the delivery of an oral care active and methods for applying oral care actives
EP3560946B1 (en) 2016-12-22 2022-02-02 KM Biologics Co., Ltd. Chromatographic method for collecting blood coagulation factor vii with high yield

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4981952A (en) * 1988-10-04 1991-01-01 Eli Lilly And Company Method for the purification of vitamin K-dependent proteins

Also Published As

Publication number Publication date
HU9502846D0 (en) 1995-12-28
JPH08508264A (ja) 1996-09-03
WO1994022905A1 (en) 1994-10-13
DK38293D0 (da) 1993-03-31
EP0691984A1 (en) 1996-01-17
CN1121723A (zh) 1996-05-01
TW278079B (fi) 1996-06-11
NO953883D0 (no) 1995-09-29
FI954649A (fi) 1995-09-29
AU677309B2 (en) 1997-04-17
HUT72712A (en) 1996-05-28
AU6423994A (en) 1994-10-24
CA2159313A1 (en) 1994-10-13
US5700914A (en) 1997-12-23
IL109164A0 (en) 1994-06-24
CZ253395A3 (en) 1996-01-17
ZA941956B (en) 1994-09-30
CN1039231C (zh) 1998-07-22
PL310887A1 (en) 1996-01-08
NO953883L (no) 1995-11-28

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