NO953270L - Fibrinogenreceptorantagonister - Google Patents
FibrinogenreceptorantagonisterInfo
- Publication number
- NO953270L NO953270L NO953270A NO953270A NO953270L NO 953270 L NO953270 L NO 953270L NO 953270 A NO953270 A NO 953270A NO 953270 A NO953270 A NO 953270A NO 953270 L NO953270 L NO 953270L
- Authority
- NO
- Norway
- Prior art keywords
- fibrinogenreceptorantagonister
- compounds
- abncn
- formula
- receptor antagonist
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- A61K38/166—Streptokinase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
Forbindelser ifølge oppfin- nelsen har formel (l) eller (2) O R2 R6 Q-(CH2)n-a-AB¿C-N-RS-C-R" m i- !,- O R2 R6 II l l Q-(CH2)n-a-AB¿C-Rs-c-R8 (2) R1 for eksempel (3). <w> (3) Forbindelsene har fibrinogenreseptor- antagonistaktivitet.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2051793A | 1993-02-22 | 1993-02-22 | |
PCT/US1994/001881 WO1994018981A1 (en) | 1993-02-22 | 1994-02-22 | Fibrinogen receptor antagonists |
Publications (2)
Publication Number | Publication Date |
---|---|
NO953270D0 NO953270D0 (no) | 1995-08-21 |
NO953270L true NO953270L (no) | 1995-10-19 |
Family
ID=21799049
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO953270A NO953270L (no) | 1993-02-22 | 1995-08-21 | Fibrinogenreceptorantagonister |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0684823A4 (no) |
JP (1) | JP3173792B2 (no) |
KR (1) | KR960700722A (no) |
CN (1) | CN1118139A (no) |
AU (1) | AU680240B2 (no) |
BG (1) | BG99863A (no) |
CA (1) | CA2155123A1 (no) |
CZ (1) | CZ210895A3 (no) |
FI (1) | FI953916A (no) |
HU (1) | HUT71796A (no) |
NO (1) | NO953270L (no) |
NZ (1) | NZ262664A (no) |
PL (1) | PL310386A1 (no) |
SK (1) | SK102495A3 (no) |
WO (1) | WO1994018981A1 (no) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5849736A (en) * | 1993-11-24 | 1998-12-15 | The Dupont Merck Pharmaceutical Company | Isoxazoline and isoxazole fibrinogen receptor antagonists |
US5494921A (en) * | 1994-09-16 | 1996-02-27 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
ZA963391B (en) * | 1995-05-24 | 1997-10-29 | Du Pont Merck Pharma | Isoxazoline fibrinogen receptor antagonists. |
NZ318926A (en) * | 1995-08-30 | 1999-04-29 | Searle & Co | Alpha v beta 3 integrin (vitronectin) inhibitors or anatagonists derived from benzoic acid for treating diseases of cell adhesion |
US6100423A (en) * | 1995-08-30 | 2000-08-08 | G. D. Searle & Co. | Amino benzenepropanoic acid compounds and derivatives thereof |
EP0854869B1 (en) | 1995-09-29 | 2004-08-25 | Eli Lilly And Company | Spiro compounds as inhibitors of fibrinogen-dependent platelet aggregation |
AU1345697A (en) * | 1995-12-22 | 1997-07-17 | Du Pont Merck Pharmaceutical Company, The | Novel integrin receptor antagonists |
AU2340997A (en) * | 1996-03-27 | 1997-10-17 | Merck & Co., Inc. | A method for inhibiting clot formation |
EA005526B1 (ru) * | 1996-07-25 | 2005-04-28 | Байоджен, Инк. | Ингибиторы клеточной адгезии |
US5900414A (en) * | 1996-08-29 | 1999-05-04 | Merck & Co., Inc. | Methods for administering integrin receptor antagonists |
DE19653647A1 (de) * | 1996-12-20 | 1998-06-25 | Hoechst Ag | Vitronectin - Rezeptorantagonisten, deren Herstellung sowie deren Verwendung |
CA2279927A1 (en) * | 1997-02-06 | 1998-08-13 | Merck & Co., Inc. | Fibrinogen receptor antagonist prodrugs |
AU6780398A (en) | 1997-03-28 | 1998-10-22 | Du Pont Merck Pharmaceutical Company, The | Heterocyclic integrin inhibitor prodrugs |
US6303625B1 (en) * | 1998-07-27 | 2001-10-16 | Ortho-Mcneil Pharmaceutical, Inc. | Triazolopyridines for the treatment of thrombosis disorders |
TR200200225T2 (tr) * | 1999-07-28 | 2002-06-21 | Avantis Pharmaceuticals Products Inc. | İkameli okzo azahetrosiklil bileşikleri |
CA2509565A1 (en) * | 2002-12-20 | 2004-07-15 | Pharmacia Corporation | Mitogen activated protein kinase-activated protein kinase-2 inhibiting compounds |
WO2008006540A1 (en) * | 2006-07-12 | 2008-01-17 | Syngenta Participations Ag | Triazolopyridine derivatives as herbicides |
AU2009244664A1 (en) * | 2008-04-04 | 2009-11-12 | Gilead Sciences, Inc. | Triazolopyridinone derivatives for use as stearoyl CoA desaturase inhibitors |
WO2010096722A1 (en) * | 2009-02-20 | 2010-08-26 | Takeda Pharmaceutical Company Limited | 3-oxo-2, 3-dihydro- [1,2, 4] triazolo [4, 3-a]pyridines as soluble epoxide hydrolase (seh) inhibitors |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5084466A (en) * | 1989-01-31 | 1992-01-28 | Hoffmann-La Roche Inc. | Novel carboxamide pyridine compounds which have useful pharmaceutical utility |
GB8913011D0 (en) * | 1989-06-06 | 1989-07-26 | Wellcome Found | Anticonvulsant pyrazines |
US5166154A (en) * | 1989-10-17 | 1992-11-24 | Boehringer Ingelheim Pharmaceuticals, Inc. | Imidazo[1,2-a]piperazines |
US5278161A (en) * | 1990-06-28 | 1994-01-11 | Hoffmann-La Roche Inc. | Amino acid derivatives useful as renin inhibitors |
-
1994
- 1994-02-22 NZ NZ262664A patent/NZ262664A/en unknown
- 1994-02-22 SK SK1024-95A patent/SK102495A3/sk unknown
- 1994-02-22 JP JP51922094A patent/JP3173792B2/ja not_active Expired - Fee Related
- 1994-02-22 CZ CZ952108A patent/CZ210895A3/cs unknown
- 1994-02-22 HU HU9502028A patent/HUT71796A/hu unknown
- 1994-02-22 WO PCT/US1994/001881 patent/WO1994018981A1/en not_active Application Discontinuation
- 1994-02-22 CA CA002155123A patent/CA2155123A1/en not_active Abandoned
- 1994-02-22 PL PL94310386A patent/PL310386A1/xx unknown
- 1994-02-22 EP EP94909745A patent/EP0684823A4/en not_active Withdrawn
- 1994-02-22 CN CN94191248A patent/CN1118139A/zh active Pending
- 1994-02-22 AU AU62465/94A patent/AU680240B2/en not_active Ceased
-
1995
- 1995-08-15 BG BG99863A patent/BG99863A/xx unknown
- 1995-08-21 NO NO953270A patent/NO953270L/no unknown
- 1995-08-21 KR KR1019950703563A patent/KR960700722A/ko not_active Application Discontinuation
- 1995-08-21 FI FI953916A patent/FI953916A/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
FI953916A0 (fi) | 1995-08-21 |
AU6246594A (en) | 1994-09-14 |
PL310386A1 (en) | 1995-12-11 |
CN1118139A (zh) | 1996-03-06 |
JP3173792B2 (ja) | 2001-06-04 |
WO1994018981A1 (en) | 1994-09-01 |
BG99863A (en) | 1996-02-29 |
NZ262664A (en) | 1997-04-24 |
KR960700722A (ko) | 1996-02-24 |
HUT71796A (en) | 1996-02-28 |
AU680240B2 (en) | 1997-07-24 |
CA2155123A1 (en) | 1994-09-01 |
FI953916A (fi) | 1995-08-21 |
HU9502028D0 (en) | 1995-09-28 |
EP0684823A4 (en) | 1997-07-09 |
JPH08507072A (ja) | 1996-07-30 |
CZ210895A3 (en) | 1996-02-14 |
EP0684823A1 (en) | 1995-12-06 |
SK102495A3 (en) | 1997-01-08 |
NO953270D0 (no) | 1995-08-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO953270L (no) | Fibrinogenreceptorantagonister | |
ZA905150B (en) | Substituted quinazolinones as angiotensin ii antagonists | |
TR200101155T2 (tr) | 4-Aroil Piperidin CCR-3 Reseptör Antagonistleri III | |
PT618190E (pt) | 9-¬glicil substituido)amido|-6-(substituido)-5-hidroxi-6-desoxitetraciclinas | |
TR200101961T2 (tr) | 1,2-halkalı kinolin türevleri | |
EA200000098A1 (ru) | 4-АМИНОПИРРОЛ(3,2-d)ПИРИМИДИНЫ В КАЧЕСТВЕ АНТАГОНИСТОВ РЕЦЕПТОРА НЕЙРОПЕПТИДА Y | |
ATE37375T1 (de) | Phosphonyl-hydroxyacyl-aminosaeure-derivate und ihre verwendung als antihypertensiva. | |
DE68925155D1 (de) | Verwendung von Halogenkohlenwasserstofflösungsmittel als Reinigungsmittel | |
MX9204661A (es) | Compuestos intermedios derivados de eter y procedimiento para su preparacion. | |
ATE203670T1 (de) | Verwendung von östrogenantagonisten und - agonisten zur hemmung pathologischer zustände | |
NO971538L (no) | Purin- og guaninforbindelser som inhibitorer for PNP | |
ES2163638T3 (es) | Nuevas n-(1-alquil-5-fenil-2,3,4,5-tetrahidro-1h-benzo(b)(1,5)diacepin-3-il)acetamidas. | |
FR2399430A1 (fr) | Chlorhydrate dihydrate de 1-(4-amino-6, 7-dimethoxy-2-quinazolinyl)-4- (2-tetrahydrofuroyl)piperazine, et son utilisation comme agents antihypertensif | |
ATE195737T1 (de) | Antagonisten des fibrinogenrezeptors | |
FI942457A (fi) | Substituoitujen piperidiinien valmistus | |
DE69426452D1 (de) | Fibrinogen receptor antagonisten | |
NO972887L (no) | Piperidineddiksyrederivater anvendelige som fibrinogen-antagonistmiddel | |
SE8500107L (sv) | Nya 8-alfa-acylaminoergoline | |
TR200001222T2 (tr) | Yeni tetrasiklikler, bunların üretimi için işlem ve bu birleşikleri içeren farmasötik preparasyonlar. | |
FI955118A0 (fi) | Herbisidiset substituoidut 1-fenyyli- tai 1-pyridinyyli-bentsotriatsolit | |
ES8701159A1 (es) | Procedimiento para la obtencion de derivados de piperidina con actividad cardiovascular. | |
ES2062389T3 (es) | Acidos glutaramicos sustituidos y sus derivados. | |
FI892222A0 (fi) | Peptidalkoholer med antikoagulantverkan. | |
NO20002408D0 (no) | 5-HT1F antagonister | |
DK365284A (da) | 5-substituerede (1,2,4)triazolo(1,5-c)pyrimidin-2-aminer |