NO943909D0 - Laktam-dipeptider som har HLE-inhiberende aktivitet - Google Patents
Laktam-dipeptider som har HLE-inhiberende aktivitetInfo
- Publication number
- NO943909D0 NO943909D0 NO943909A NO943909A NO943909D0 NO 943909 D0 NO943909 D0 NO 943909D0 NO 943909 A NO943909 A NO 943909A NO 943909 A NO943909 A NO 943909A NO 943909 D0 NO943909 D0 NO 943909D0
- Authority
- NO
- Norway
- Prior art keywords
- heterocyclic compounds
- hle
- dipeptides
- lactam
- inhibitory activity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929208379A GB9208379D0 (en) | 1992-04-16 | 1992-04-16 | Heterocyclic amines |
GB929208380A GB9208380D0 (en) | 1992-04-16 | 1992-04-16 | Heterocyclic compounds |
GB929214448A GB9214448D0 (en) | 1992-07-08 | 1992-07-08 | Heterocyclic agents |
GB929217364A GB9217364D0 (en) | 1992-08-14 | 1992-08-14 | Heterocyclic agents |
GB929217362A GB9217362D0 (en) | 1992-08-14 | 1992-08-14 | Heterocyclic compounds |
GB929217363A GB9217363D0 (en) | 1992-08-14 | 1992-08-14 | Heterocyclic amines |
PCT/GB1993/000794 WO1993021212A1 (en) | 1992-04-16 | 1993-04-15 | Lactam dipeptides having hle inhibiting activity |
Publications (2)
Publication Number | Publication Date |
---|---|
NO943909L NO943909L (no) | 1994-10-14 |
NO943909D0 true NO943909D0 (no) | 1994-10-14 |
Family
ID=27547161
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO943909A NO943909D0 (no) | 1992-04-16 | 1994-10-14 | Laktam-dipeptider som har HLE-inhiberende aktivitet |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0630382B1 (no) |
JP (1) | JPH07505873A (no) |
AT (1) | ATE149175T1 (no) |
AU (1) | AU4076993A (no) |
CA (1) | CA2132543A1 (no) |
DE (1) | DE69308291T2 (no) |
FI (1) | FI944802A0 (no) |
GB (1) | GB9307555D0 (no) |
HU (1) | HUT70430A (no) |
IL (1) | IL105424A0 (no) |
MX (1) | MX9302215A (no) |
NO (1) | NO943909D0 (no) |
WO (1) | WO1993021212A1 (no) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6001813A (en) * | 1994-11-21 | 1999-12-14 | Cortech Inc. | Val-pro containing α-keto oxadiazoles as serine protease inhibitors |
US5618792A (en) * | 1994-11-21 | 1997-04-08 | Cortech, Inc. | Substituted heterocyclic compounds useful as inhibitors of (serine proteases) human neutrophil elastase |
US6100238A (en) * | 1994-11-21 | 2000-08-08 | Cortech Inc. | Indole and tetrahydroisoquinoline containing Alpha-keto oxadiazoles as serine protease inhibitors |
US6159938A (en) * | 1994-11-21 | 2000-12-12 | Cortech, Inc. | Serine protease inhibitors comprising α-keto heterocycles |
US6001811A (en) * | 1994-11-21 | 1999-12-14 | Cortech Inc. | Serine protease inhibitors--N-substituted derivatives |
US20020119985A1 (en) | 1994-11-21 | 2002-08-29 | Albert Gyorkos | Serine protease inhibitors |
US6001814A (en) * | 1994-11-21 | 1999-12-14 | Cortech Inc. | Serine protease inhibitors |
US6150334A (en) * | 1994-11-21 | 2000-11-21 | Cortech, Inc. | Serine protease inhibitors-tripeptoid analogs |
US5998379A (en) * | 1994-11-21 | 1999-12-07 | Cortech Inc. | Serine protease inhibitors-proline analogs |
US6015791A (en) * | 1994-11-21 | 2000-01-18 | Cortech Inc. | Serine protease inhibitors-cycloheptane derivatives |
KR100400639B1 (ko) * | 1995-04-27 | 2003-12-31 | 미쯔비시 웰 파마 가부시키가이샤 | 복소환식아미드화합물및그의의약용도 |
NZ336046A (en) * | 1996-12-06 | 2000-10-27 | Cortech Inc | Serine protease inhibitors containing substituted oxadiazole, thiadiazole and triazole peptide derivatives |
US6656910B2 (en) | 1997-12-04 | 2003-12-02 | Cortech, Inc. | Serine protease inhibitors |
WO2000032216A1 (en) | 1998-06-03 | 2000-06-08 | Cortech Inc. | Peptoid and nonpeptoid containing alpha-keto oxadiazoles as serine protease inhibitors |
EP1842884A3 (en) | 2001-07-30 | 2010-11-24 | Sanko Chemical Industry Co., Ltd. | Antistatic composition and method for production |
IL163453A0 (en) | 2004-08-10 | 2009-02-11 | Yeda Res & Dev | Enzyme inhibitor in leukemia |
BRPI1015259A2 (pt) * | 2009-04-27 | 2016-05-03 | Elan Pharm Inc | antagonistas de piridinona de integrinas alfa-4 |
US20220354833A1 (en) | 2019-09-17 | 2022-11-10 | Mereo Biopharma 4 Limited | Alvelestat for use in the treatment of graft rejection, bronchiolitis obliterans syndrome and graft versus host disease |
IL297211A (en) | 2020-04-16 | 2022-12-01 | Mereo Biopharma 4 Ltd | Methods involving the neutrophil elastase inhibitor albalstat for the treatment of respiratory disease mediated by alpha-1 antitrypsin deficiency |
CA3234399A1 (en) | 2021-10-20 | 2023-04-27 | Mereo Biopharma 4 Limited | Neutrophil elastase inhibitors for use in the treatment of fibrosis |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0369391A3 (en) * | 1988-11-15 | 1991-09-25 | Boehringer Ingelheim Pharmaceuticals Inc. | N-substituted amides |
GB9207145D0 (en) * | 1991-04-18 | 1992-05-13 | Ici Plc | Heterocyclic amides |
-
1993
- 1993-04-13 GB GB939307555A patent/GB9307555D0/en active Pending
- 1993-04-15 WO PCT/GB1993/000794 patent/WO1993021212A1/en active IP Right Grant
- 1993-04-15 AU AU40769/93A patent/AU4076993A/en not_active Abandoned
- 1993-04-15 CA CA002132543A patent/CA2132543A1/en not_active Abandoned
- 1993-04-15 DE DE69308291T patent/DE69308291T2/de not_active Expired - Fee Related
- 1993-04-15 EP EP93910157A patent/EP0630382B1/en not_active Expired - Lifetime
- 1993-04-15 HU HU9402968A patent/HUT70430A/hu unknown
- 1993-04-15 AT AT93910157T patent/ATE149175T1/de active
- 1993-04-15 JP JP5518137A patent/JPH07505873A/ja active Pending
- 1993-04-16 MX MX9302215A patent/MX9302215A/es unknown
- 1993-04-16 IL IL105424A patent/IL105424A0/xx unknown
-
1994
- 1994-10-12 FI FI944802A patent/FI944802A0/fi not_active Application Discontinuation
- 1994-10-14 NO NO943909A patent/NO943909D0/no unknown
Also Published As
Publication number | Publication date |
---|---|
DE69308291D1 (de) | 1997-04-03 |
EP0630382A1 (en) | 1994-12-28 |
AU4076993A (en) | 1993-11-18 |
DE69308291T2 (de) | 1997-06-26 |
HUT70430A (en) | 1995-10-30 |
MX9302215A (es) | 1993-10-01 |
HU9402968D0 (en) | 1995-02-28 |
ATE149175T1 (de) | 1997-03-15 |
FI944802A (fi) | 1994-10-12 |
FI944802A0 (fi) | 1994-10-12 |
JPH07505873A (ja) | 1995-06-29 |
IL105424A0 (en) | 1993-08-18 |
GB9307555D0 (en) | 1993-06-02 |
WO1993021212A1 (en) | 1993-10-28 |
NO943909L (no) | 1994-10-14 |
CA2132543A1 (en) | 1993-10-28 |
EP0630382B1 (en) | 1997-02-26 |
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