NO942920D0 - - Google Patents
Info
- Publication number
- NO942920D0 NO942920D0 NO942920A NO942920A NO942920D0 NO 942920 D0 NO942920 D0 NO 942920D0 NO 942920 A NO942920 A NO 942920A NO 942920 A NO942920 A NO 942920A NO 942920 D0 NO942920 D0 NO 942920D0
- Authority
- NO
- Norway
- Prior art keywords
- integer
- tumors
- group
- phenyl group
- substituted
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/04—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83254092A | 1992-02-06 | 1992-02-06 | |
PCT/US1993/000669 WO1993016044A1 (en) | 1992-02-06 | 1993-01-11 | Reversal of multi-drug resistance by triphenyl-azacycloalkane derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
NO942920D0 true NO942920D0 (ja) | 1994-08-05 |
NO942920L NO942920L (no) | 1994-08-05 |
Family
ID=25261950
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO942920A NO942920L (no) | 1992-02-06 | 1994-08-05 | Reversering av flerlegemiddelresistens med trifenylazasykloalkanderivater |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0643693B1 (ja) |
JP (1) | JPH07503957A (ja) |
KR (1) | KR950700248A (ja) |
AT (1) | ATE182582T1 (ja) |
AU (1) | AU662602B2 (ja) |
CA (1) | CA2129144C (ja) |
DE (1) | DE69325805T2 (ja) |
DK (1) | DK0643693T3 (ja) |
ES (1) | ES2135463T3 (ja) |
GR (1) | GR3031557T3 (ja) |
HU (1) | HUT70564A (ja) |
NO (1) | NO942920L (ja) |
NZ (1) | NZ249040A (ja) |
WO (1) | WO1993016044A1 (ja) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69309310T2 (de) * | 1993-01-21 | 1997-11-06 | Merrell Pharmaceuticals Inc., Cincinnati, Ohio | Als mittel gegen mehrfach resistente tumorenverwendbare diarylalkylpiperidine |
US5670521A (en) * | 1994-08-05 | 1997-09-23 | Merrell Pharmaceuticals Inc. | Reversal of multi-drug resistance by triphenyl-azacycloalkane derivatives |
WO1996006604A2 (en) | 1994-08-31 | 1996-03-07 | Eli Lilly And Company | Methods for identifying and treating resistant tumors |
TW527186B (en) | 1996-03-19 | 2003-04-11 | Janssen Pharmaceutica Nv | Fused imidazole derivatives as multidrug resistance modulators |
GB0003685D0 (en) * | 2000-02-17 | 2000-04-05 | Univ Cardiff | Sensitisation of cellular material |
CN110372571B (zh) * | 2018-04-12 | 2022-11-15 | 中国科学院大连化学物理研究所 | 一种2-(2,2-二芳基乙基)-环胺衍生物或盐及合成和应用与组合物 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1049377B (de) * | 1952-04-03 | 1959-01-29 | Abbott Laboratories, North Chicago, 111. (V. St. A.) | Verfahren zur Herstellung von substituierten Vinylpiperidinen |
EP0235463A3 (en) * | 1985-12-20 | 1990-01-17 | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) | N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents |
WO1990015599A1 (en) * | 1989-06-19 | 1990-12-27 | The Wellcome Foundation Limited | Medicaments useful in cancer therapy and having antihistaminic properties |
GB9000305D0 (en) * | 1990-01-06 | 1990-03-07 | Pfizer Ltd | Anticholinergic agents |
EP0467435A3 (en) * | 1990-07-19 | 1992-04-01 | Akzo N.V. | Benzhydryl derivatives having calmodulin inhibitor properties |
DE69309310T2 (de) * | 1993-01-21 | 1997-11-06 | Merrell Pharmaceuticals Inc., Cincinnati, Ohio | Als mittel gegen mehrfach resistente tumorenverwendbare diarylalkylpiperidine |
-
1993
- 1993-01-11 AU AU34842/93A patent/AU662602B2/en not_active Ceased
- 1993-01-11 ES ES93903678T patent/ES2135463T3/es not_active Expired - Lifetime
- 1993-01-11 NZ NZ249040A patent/NZ249040A/en unknown
- 1993-01-11 JP JP5514096A patent/JPH07503957A/ja active Pending
- 1993-01-11 CA CA002129144A patent/CA2129144C/en not_active Expired - Fee Related
- 1993-01-11 DK DK93903678T patent/DK0643693T3/da active
- 1993-01-11 WO PCT/US1993/000669 patent/WO1993016044A1/en active IP Right Grant
- 1993-01-11 AT AT93903678T patent/ATE182582T1/de not_active IP Right Cessation
- 1993-01-11 HU HU9402298A patent/HUT70564A/hu unknown
- 1993-01-11 EP EP93903678A patent/EP0643693B1/en not_active Expired - Lifetime
- 1993-01-11 DE DE69325805T patent/DE69325805T2/de not_active Expired - Fee Related
-
1994
- 1994-08-05 NO NO942920A patent/NO942920L/no unknown
- 1994-08-05 KR KR1019940702687A patent/KR950700248A/ko not_active Application Discontinuation
-
1999
- 1999-10-15 GR GR990402651T patent/GR3031557T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA2129144C (en) | 1999-07-13 |
AU662602B2 (en) | 1995-09-07 |
CA2129144A1 (en) | 1993-08-19 |
DK0643693T3 (da) | 1999-11-29 |
GR3031557T3 (en) | 2000-01-31 |
NZ249040A (en) | 1997-06-24 |
KR950700248A (ko) | 1995-01-16 |
DE69325805D1 (de) | 1999-09-02 |
ATE182582T1 (de) | 1999-08-15 |
NO942920L (no) | 1994-08-05 |
AU3484293A (en) | 1993-09-03 |
DE69325805T2 (de) | 2000-03-16 |
JPH07503957A (ja) | 1995-04-27 |
ES2135463T3 (es) | 1999-11-01 |
HU9402298D0 (en) | 1994-10-28 |
EP0643693A1 (en) | 1995-03-22 |
HUT70564A (en) | 1995-10-30 |
WO1993016044A1 (en) | 1993-08-19 |
EP0643693B1 (en) | 1999-07-28 |
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