NO940974L - Benzanilid-derivater som 5-HT1D antagonister - Google Patents

Benzanilid-derivater som 5-HT1D antagonister

Info

Publication number
NO940974L
NO940974L NO940974A NO940974A NO940974L NO 940974 L NO940974 L NO 940974L NO 940974 A NO940974 A NO 940974A NO 940974 A NO940974 A NO 940974A NO 940974 L NO940974 L NO 940974L
Authority
NO
Norway
Prior art keywords
benzanilide derivatives
ht1d antagonists
ht1d
antagonists
benzanilide
Prior art date
Application number
NO940974A
Other languages
English (en)
Other versions
NO940974D0 (no
Inventor
Alexander William Oxford
William Leonard Mitchell
John Bradshaw
John Watson Clitherow
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NO940974D0 publication Critical patent/NO940974D0/no
Publication of NO940974L publication Critical patent/NO940974L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
NO940974A 1991-09-18 1994-03-17 Benzanilid-derivater som 5-HT1D antagonister NO940974L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB919119932A GB9119932D0 (en) 1991-09-18 1991-09-18 Chemical compounds
PCT/EP1992/002136 WO1993006084A1 (en) 1991-09-18 1992-09-14 Benzanilide derivatives as 5-ht1d antagonists
CN93100710A CN1089944A (zh) 1991-09-18 1993-01-09 N-苯甲酰苯胺衍生物

Publications (2)

Publication Number Publication Date
NO940974D0 NO940974D0 (no) 1994-03-17
NO940974L true NO940974L (no) 1994-03-17

Family

ID=36792802

Family Applications (1)

Application Number Title Priority Date Filing Date
NO940974A NO940974L (no) 1991-09-18 1994-03-17 Benzanilid-derivater som 5-HT1D antagonister

Country Status (14)

Country Link
US (1) US5358948A (no)
EP (1) EP0533267A1 (no)
JP (1) JPH06107637A (no)
CN (2) CN1073430A (no)
AU (2) AU2568792A (no)
CA (1) CA2078507A1 (no)
CZ (1) CZ61194A3 (no)
FI (1) FI941261A (no)
GB (1) GB9119932D0 (no)
IL (1) IL103199A0 (no)
MX (1) MX9205278A (no)
NO (1) NO940974L (no)
WO (1) WO1993006084A1 (no)
ZA (1) ZA927106B (no)

Families Citing this family (64)

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EP0712397B1 (en) * 1993-08-06 1999-04-21 Smithkline Beecham Plc Amide derivatives as 5ht1d receptor antagonists
DE69411176T2 (de) * 1993-08-20 1998-11-12 Smithkline Beecham Plc Amide und harnstoffderivate als 5ht1d rezeptor antagonisten
EP0716656A1 (en) * 1993-09-03 1996-06-19 Smithkline Beecham Plc Amide derivatives as 5ht1d receptor antagonists
EP0716650B1 (en) * 1993-09-03 1999-03-24 Smithkline Beecham Plc Indole and indoline derivatives as 5ht1d receptor antagonists
JPH09503773A (ja) * 1993-10-19 1997-04-15 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー ５ｈｔ−１ｄレセプター拮抗剤用のベンズアニリド誘導体
AU1108395A (en) * 1993-12-07 1995-06-27 Smithkline Beecham Plc Heterocyclic biphenylylamides useful as 5ht1d antagonists
JPH09512804A (ja) * 1994-05-06 1997-12-22 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー ５−ｈｔ１ｄアンタゴニストとして有用なビフェニルカルボキシアミド類
GB9410512D0 (en) * 1994-05-25 1994-07-13 Smithkline Beecham Plc Novel treatment
WO1995032967A1 (en) * 1994-05-28 1995-12-07 Smithkline Beecham Plc Amide derivatives having 5ht1d-antagonist activity
FR2722788B1 (fr) * 1994-07-20 1996-10-04 Pf Medicament Nouvelles piperazides derivees d'aryl piperazine, leurs procedes de preparation, leur utilisation a titre de medicament et les compositions pharmaceutiques les comprenant
GB9416972D0 (en) * 1994-08-23 1994-10-12 Smithkline Beecham Plc Carbon side chain/indole/indolene
CN1175256A (zh) * 1994-12-22 1998-03-04 史密丝克莱恩比彻姆有限公司 四环螺环化合物,其制备方法及其作为5ht1d受体拮抗剂的应用
GB9507203D0 (en) * 1995-04-07 1995-05-31 Smithkline Beecham Plc Novel compounds
FR2740134B1 (fr) * 1995-10-18 1998-01-09 Pf Medicament Derives d'amines cycliques d'aryl-piperazines, leur preparation et les compositions pharmaceutiques les contenant
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FR2744450A1 (fr) * 1996-02-02 1997-08-08 Pf Medicament Nouvelles naphtylpiperazines derivees de cycloazanes substitues, ainsi que leur procede de preparation, les compositions pharmaceutiques et leur utilisation comme medicaments
FR2744449B1 (fr) * 1996-02-02 1998-04-24 Pf Medicament Nouvelles piperazines aromatiques derivees de cycloazanes substitues, ainsi que leur procede de preparation, les compositions pharmaceutiques et leur utilisation comme medicaments
SE9601110D0 (sv) 1996-03-22 1996-03-22 Astra Ab Substituted 1,2,3,4-tetrahydronaphthalene derivatives
GB9606396D0 (en) * 1996-03-27 1996-06-05 Smithkline Beecham Plc Novel compounds
US6156783A (en) * 1996-04-30 2000-12-05 Smithkline Beecham P.L.C. Spiroazabicyclic compounds, processes for their preparation, and their pharmaceutical use
GB9625145D0 (en) * 1996-12-03 1997-01-22 Smithkline Beecham Plc Novel compounds
DZ2376A1 (fr) * 1996-12-19 2002-12-28 Smithkline Beecham Plc Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant.
WO1998027058A2 (en) * 1996-12-19 1998-06-25 Smithkline Beecham Plc N-piperazin-1-ylphenyl-benzamide derivatives
FR2761064B1 (fr) * 1997-03-20 1999-06-04 Pf Medicament Piperazines derivees d'amines cycliques, leur preparation et leur application comme medicaments
TR199902590T2 (xx) * 1997-04-18 2000-06-21 Smithkline Beecham P.L.C. Birle�ik 5HT1A 5HT1B ve 5HT1D resept�r antagonist aktivitesi olan indol t�revleri.
SE9900190D0 (sv) 1999-01-22 1999-01-22 Astra Ab New compounds
SE9702799D0 (sv) 1997-07-25 1997-07-25 Astra Ab New compounds
CA2299286A1 (en) 1997-08-09 1999-02-18 Laramie Mary Gaster Bicyclic compounds as ligands for 5-ht1 receptors
SE9703375D0 (sv) * 1997-09-18 1997-09-18 Astra Ab A new combination
SE9703376D0 (sv) * 1997-09-18 1997-09-18 Astra Ab A new combination
GB9818914D0 (en) * 1998-08-28 1998-10-21 Smithkline Beecham Plc Use
GB9826412D0 (en) 1998-12-03 1999-01-27 Glaxo Group Ltd Chemical compounds
US6365591B1 (en) 1999-10-18 2002-04-02 Recordati, S.A., Chemical And Pharmacueticals Company Isoxazolecarboxamide derivatives
SE9904723D0 (sv) 1999-12-22 1999-12-22 Carlsson A Research Ab New modulators of dopamine neurotransmission II
USRE46117E1 (en) 1999-12-22 2016-08-23 Teva Pharmaceuticals International Gmbh Modulators of dopamine neurotransmission
SE9904724D0 (sv) 1999-12-22 1999-12-22 Carlsson A Research Ab New modulators of dopamine neurotransmission I
GB2362826A (en) * 2000-06-02 2001-12-05 Lilly Co Eli A pharmaceutical composition comprising a serotonin transport inhibitor and a serotonin recptor antagonist
JO2654B1 (en) 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JP4119114B2 (ja) * 2001-11-28 2008-07-16 広栄化学工業株式会社 新規なジヒドロキシ（３−ピリジル）ボラン類
CA2510471A1 (en) * 2002-12-19 2004-07-08 Neurogen Corporation Substituted biphenyl-4-carboxylic acid arylamide analogues as capsaicin receptor modulators
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US7037927B2 (en) 2003-10-16 2006-05-02 Abbott Laboratories Amides that inhibit vanilloid receptor subtype 1 (VR1) receptor
DE602004028150D1 (de) * 2003-11-26 2010-08-26 Pfizer Prod Inc Aminopyrazolderivate als gsk-3-inhibitoren
WO2005073193A1 (en) * 2004-01-23 2005-08-11 Amgen Inc. Vanilloid receptor ligands and their use in treatments
CN1950332A (zh) * 2004-03-02 2007-04-18 神经能质公司 经杂烷基取代的联苯－4－羧酸芳基醯胺类似物
SE0401465D0 (sv) 2004-06-08 2004-06-08 Carlsson A Research Ab New substituted piperdines as modulators of dopamine neurotransmission
MXPA06013941A (es) 2004-06-08 2007-12-10 Neurosearch Sweden Ab Fenilpiperidinas disustituidas, novedosas, como moduladores de la neurotransmision de dopamina y serotonina.
US7851629B2 (en) 2004-06-08 2010-12-14 Nsab, Filial Af Neurosearch Sweden Ab, Sverige Disubstituted phenylpiperidines as modulators of dopamine and serotonin neurotransmission
ES2659577T3 (es) 2004-10-13 2018-03-16 Teva Pharmaceuticals International Gmbh Proceso para la síntesis de 4-(3-metanosulfonilfenil)-1-N-propil-piperidina
SE529246C2 (sv) 2005-10-13 2007-06-12 Neurosearch Sweden Ab Nya disubstituerade fenyl-piperidiner som modulatorer för dopaminneurotransmission
SG177911A1 (en) * 2006-12-21 2012-02-28 Nerviano Medical Sciences Srl Substituted pyrazolo-quinazoline derivatives, process for their preparation and their use as kinase inhibitors
KR100851044B1 (ko) * 2007-08-21 2008-08-12 (주)아모레퍼시픽 미백효과를 나타내는 3,5-디히드록시 벤즈아미드 유도체,및 이를 함유하는 화장료 조성물
BRPI0915205A2 (pt) * 2008-06-11 2017-03-21 Dana Farber Cancer Inst Inc compostos e composições úteis para o tratamento de malária
WO2011057416A1 (en) * 2009-11-13 2011-05-19 Packers Plus Energy Services Inc. Stage tool for wellbore cementing
US8846671B2 (en) * 2010-07-01 2014-09-30 Guangzhou Institute Of Biomedicine And Health, Chinese Academy Of Sciences Heterocyclic alkynyl benzene compounds and medical compositions and uses thereof
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CN107108581B (zh) * 2014-08-21 2020-06-23 百时美施贵宝公司 作为强效rock抑制剂的回接苯甲酰胺衍生物
CN108219913B (zh) * 2018-02-27 2021-07-20 浙江绿保再生资源科技有限公司 一种复合絮凝剂及废润滑油絮凝再生工艺
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Also Published As

Publication number Publication date
ZA927106B (en) 1994-03-17
IL103199A0 (en) 1993-02-21
NO940974D0 (no) 1994-03-17
JPH06107637A (ja) 1994-04-19
CA2078507A1 (en) 1993-03-19
EP0533267A1 (en) 1993-03-24
AU2568792A (en) 1993-04-27
FI941261A0 (fi) 1994-03-17
FI941261A (fi) 1994-03-17
CZ61194A3 (en) 1994-11-16
US5358948A (en) 1994-10-25
GB9119932D0 (en) 1991-10-30
CN1073430A (zh) 1993-06-23
AU2452892A (en) 1993-03-25
CN1089944A (zh) 1994-07-27
WO1993006084A1 (en) 1993-04-01
MX9205278A (es) 1993-03-01

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