NO934776D0 - Rensing av rekombinant apoliproteiner E fra bakterier - Google Patents
Rensing av rekombinant apoliproteiner E fra bakterierInfo
- Publication number
- NO934776D0 NO934776D0 NO934776A NO934776A NO934776D0 NO 934776 D0 NO934776 D0 NO 934776D0 NO 934776 A NO934776 A NO 934776A NO 934776 A NO934776 A NO 934776A NO 934776 D0 NO934776 D0 NO 934776D0
- Authority
- NO
- Norway
- Prior art keywords
- analog
- apoe
- recombinant
- purification process
- fatty acids
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/06—Lysis of microorganisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/803—Physical recovery methods, e.g. chromatography, grinding
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1991/004553 WO1993000443A1 (en) | 1991-06-26 | 1991-06-26 | Purification of recombinant apolipoprotein e from bacteria |
NZ238813A NZ238813A (en) | 1991-06-26 | 1991-07-01 | Production and purification of apolipoprotein e (apo e) and its use |
US08/333,872 US5525472A (en) | 1991-06-26 | 1994-11-03 | Method for production and purification or recombinant Apolipoprotein E from bacteria |
Publications (2)
Publication Number | Publication Date |
---|---|
NO934776D0 true NO934776D0 (no) | 1993-12-22 |
NO934776L NO934776L (no) | 1994-02-17 |
Family
ID=27353645
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO934776A NO934776L (no) | 1991-06-26 | 1993-12-22 | Rensing av rekombinant apoliproteiner E fra bakterier |
Country Status (3)
Country | Link |
---|---|
US (1) | US5525472A (no) |
NO (1) | NO934776L (no) |
WO (1) | WO1993000443A1 (no) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2167942A1 (en) * | 1993-08-12 | 1995-02-23 | Tikva Vogel | Method of inhibiting kaposi's sarcoma |
SE9500778D0 (sv) * | 1995-03-03 | 1995-03-03 | Pharmacia Ab | Process for producing a protein |
US6277874B1 (en) * | 1996-07-09 | 2001-08-21 | University Of Cincinnati And Apologic, Incorporated | Methods for the treatment of apolipoprotein E related diseases |
WO1998011140A1 (en) * | 1996-09-11 | 1998-03-19 | Pharmacia & Upjohn Ab | A process for purifying apolipoproteins and a composition for use in the process |
NZ334589A (en) * | 1996-09-11 | 2000-07-28 | Pharmacia & Upjohn Ab | Aqueous two-phase system for purifying apolipoproteins |
EP1267908B1 (en) * | 2000-03-03 | 2004-05-06 | GlaxoSmithKline Biologicals S.A. | Vaccine for the treatment of atherosclerosis |
US6555391B1 (en) * | 2000-08-15 | 2003-04-29 | Baxter International, Inc. | Methods of conditioning an affinity resin after storage |
CN1268641C (zh) * | 2000-11-10 | 2006-08-09 | 普罗蒂奥制药公司 | 载脂蛋白类似物 |
CN1312273C (zh) * | 2002-09-30 | 2007-04-25 | 中国科学院沈阳应用生态研究所 | 一种光合细菌培养基用添加剂 |
DE10309691B4 (de) * | 2003-02-28 | 2018-10-04 | Hans-Knöll-Institut für Naturstoff-Forschung e.V. | Gewinnung von löslichen Proteinen aus der Biomasse rekombinanter Mikroorganismen |
GB0329254D0 (en) * | 2003-12-17 | 2004-01-21 | Univ Manchester | Treatment of viral infections |
US8013122B2 (en) * | 2006-12-20 | 2011-09-06 | Kieu Hoang | Method of purifying apolipoprotein A-1 |
CN100586958C (zh) * | 2006-12-20 | 2010-02-03 | 上海莱士血液制品股份有限公司 | 高纯度载脂蛋白a-i的制备方法 |
US8324366B2 (en) * | 2008-04-29 | 2012-12-04 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for delivering RNAI using lipoproteins |
KR20210158864A (ko) | 2008-11-10 | 2021-12-31 | 알닐람 파마슈티칼스 인코포레이티드 | 치료제 운반용 신규 지질 및 조성물 |
AU2010208035B2 (en) | 2009-01-29 | 2016-06-23 | Arbutus Biopharma Corporation | Improved lipid formulation for the delivery of nucleic acids |
WO2010105209A1 (en) | 2009-03-12 | 2010-09-16 | Alnylam Pharmaceuticals, Inc. | LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF Eg5 AND VEGF GENES |
EP3097908A1 (en) | 2009-05-05 | 2016-11-30 | Arbutus Biopharma Corporation | Lipid compositions |
PT3431076T (pt) | 2009-06-10 | 2021-10-26 | Arbutus Biopharma Corp | Formulação lipídica melhorada |
WO2011020023A2 (en) | 2009-08-14 | 2011-02-17 | Alnylam Pharmaceuticals, Inc. | Lipid formulated compositions and methods for inhibiting expression of a gene from the ebola virus |
US20120245076A1 (en) * | 2009-09-03 | 2012-09-27 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for delivering rnai using apoe |
CA2783372C (en) | 2009-12-07 | 2019-07-16 | Muthiah Manoharan | Compositions for nucleic acid delivery |
ES2749426T3 (es) | 2009-12-18 | 2020-03-20 | Univ British Columbia | Métodos y composiciones para administración de ácidos nucleicos |
WO2011139911A2 (en) | 2010-04-29 | 2011-11-10 | Isis Pharmaceuticals, Inc. | Lipid formulated single stranded rna |
EP2569276B1 (en) | 2010-05-12 | 2021-02-24 | Arbutus Biopharma Corporation | Novel cationic lipids and methods of use thereof |
US10077232B2 (en) | 2010-05-12 | 2018-09-18 | Arbutus Biopharma Corporation | Cyclic cationic lipids and methods of use |
EP3254672A1 (en) | 2010-06-03 | 2017-12-13 | Alnylam Pharmaceuticals, Inc. | Biodegradable lipids for the delivery of active agents |
US20130323269A1 (en) | 2010-07-30 | 2013-12-05 | Muthiah Manoharan | Methods and compositions for delivery of active agents |
WO2012016188A2 (en) | 2010-07-30 | 2012-02-02 | Alnylam Pharmaceuticals, Inc. | Methods and compositions for delivery of active agents |
CN110123830A (zh) | 2010-11-09 | 2019-08-16 | 阿尔尼拉姆医药品有限公司 | 用于抑制Eg5和VEGF基因的表达的脂质配制的组合物和方法 |
DK2663548T3 (en) | 2011-01-11 | 2017-07-24 | Alnylam Pharmaceuticals Inc | PEGYLED LIPIDS AND THEIR USE FOR PHARMACEUTICAL SUPPLY |
DK2767546T3 (en) | 2011-02-07 | 2019-02-04 | Cerenis Therapeutics Holding Sa | Lipoprotein complexes and their preparation and uses |
AU2012315965A1 (en) | 2011-09-27 | 2014-04-03 | Alnylam Pharmaceuticals, Inc. | Di-aliphatic substituted PEGylated lipids |
WO2014011908A1 (en) | 2012-07-11 | 2014-01-16 | Esperion Therapeutics, Inc. | Apolipoprotein mixtures |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2652636A1 (de) * | 1976-11-19 | 1978-05-24 | Hans Uwe Dr Rer Nat Wolf | Verfahren zur stabilisierung von proteinen und verwandten verbindungen waehrend ihrer reinigung, isolierung und lagerung |
US4656132A (en) * | 1984-03-28 | 1987-04-07 | Cetus Corporation | Method of improving the yield of heterologous protein produced by cultivating recombinant bacteria |
AU587989B2 (en) * | 1984-10-16 | 1989-09-07 | Mitsubishi Chemical Corporation | DMA fragments, expression vectors, proteins, hosts, and process for production of the proteins |
US4943527A (en) * | 1985-10-04 | 1990-07-24 | California Biotechnology Inc. | Mature apoai protein production under serum free culturing conditions |
US5049488A (en) * | 1985-11-08 | 1991-09-17 | Genentech, Inc. | Method and nucleic acid for the preparation of lecithin:cholesterol acyltransferase |
GB8625435D0 (en) * | 1986-10-23 | 1986-11-26 | Erba Farmitalia | Human apolipoprotein ai |
CA1335077C (en) * | 1988-02-08 | 1995-04-04 | Henri Isliker | Process for the manufacture of apolipoproteins from human blood plasma or serum |
-
1991
- 1991-06-26 WO PCT/US1991/004553 patent/WO1993000443A1/en not_active Application Discontinuation
-
1993
- 1993-12-22 NO NO934776A patent/NO934776L/no unknown
-
1994
- 1994-11-03 US US08/333,872 patent/US5525472A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO1993000443A1 (en) | 1993-01-07 |
US5525472A (en) | 1996-06-11 |
NO934776L (no) | 1994-02-17 |
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