NO933726L - Inhibitorer for kynureninase - Google Patents
Inhibitorer for kynureninaseInfo
- Publication number
- NO933726L NO933726L NO933726A NO933726A NO933726L NO 933726 L NO933726 L NO 933726L NO 933726 A NO933726 A NO 933726A NO 933726 A NO933726 A NO 933726A NO 933726 L NO933726 L NO 933726L
- Authority
- NO
- Norway
- Prior art keywords
- carbon atoms
- alkyl group
- halogen
- small alkyl
- kynureninase
- Prior art date
Links
- 108010031676 Kynureninase Proteins 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title abstract 3
- 102000005447 kynureninase Human genes 0.000 title abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 150000002367 halogens Chemical class 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
- C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/689,705 US5254725A (en) | 1991-04-18 | 1991-04-18 | Inhibitors of kynureninase |
| US84040892A | 1992-02-24 | 1992-02-24 | |
| PCT/US1992/003198 WO1992018003A1 (en) | 1991-04-18 | 1992-04-17 | Inhibitors of kynureninase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO933726D0 NO933726D0 (no) | 1993-10-15 |
| NO933726L true NO933726L (no) | 1993-12-15 |
Family
ID=27104468
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO933726A NO933726L (no) | 1991-04-18 | 1993-10-15 | Inhibitorer for kynureninase |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US5516936A (enExample) |
| EP (1) | EP0581907A1 (enExample) |
| JP (1) | JPH06510023A (enExample) |
| AU (1) | AU668508B2 (enExample) |
| CA (1) | CA2108670A1 (enExample) |
| NO (1) | NO933726L (enExample) |
| WO (1) | WO1992018003A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1265101B1 (it) * | 1993-07-23 | 1996-10-30 | Erba Carlo Spa | Derivati dell'acido 2-ammino-4-fenil-4-osso butirrico |
| US5519055A (en) * | 1993-08-06 | 1996-05-21 | University Of Maryland At Baltimore | Substituted kynurenines and process for their preparation |
| US5786508A (en) * | 1994-07-15 | 1998-07-28 | Pharmacia & Upjohn S.P.A. | Substituted kynurenines and process for their preparation |
| EP0897911B9 (en) * | 1997-01-14 | 2004-12-01 | Kaneka Corporation | Process for producing cysteine derivatives |
| US6028354A (en) | 1997-10-14 | 2000-02-22 | Amkor Technology, Inc. | Microelectronic device package having a heat sink structure for increasing the thermal conductivity of the package |
| US6583299B1 (en) * | 1999-05-20 | 2003-06-24 | G.D. Searle & Co. | α-amino-β-sulfonyl hydroxamic acid compounds |
| WO2016027757A1 (ja) * | 2014-08-18 | 2016-02-25 | 国立大学法人大阪大学 | 新規２－アミノベンゾイル誘導体 |
| WO2018231462A1 (en) | 2017-06-14 | 2018-12-20 | Codexis, Inc. | Engineered transaminase polypeptides for industrial biocatalysis |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4293569A (en) * | 1978-05-12 | 1981-10-06 | E. R. Squibb & Sons, Inc. | Substituted phenylguanindines and method |
| US4332813A (en) * | 1979-08-15 | 1982-06-01 | Merck & Co., Inc. | Allylsulfoxide enzyme inhibitors |
| DE3400514A1 (de) * | 1984-01-10 | 1985-07-18 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue carbonsaeure-derivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel |
| GB8426200D0 (en) * | 1984-10-17 | 1984-11-21 | Glaxo Holdings Ltd | Chemical compounds |
| US5254725A (en) * | 1991-04-18 | 1993-10-19 | University Of Georgia Research Foundation, Inc. | Inhibitors of kynureninase |
-
1992
- 1992-04-17 US US08/137,100 patent/US5516936A/en not_active Expired - Fee Related
- 1992-04-17 CA CA002108670A patent/CA2108670A1/en not_active Abandoned
- 1992-04-17 JP JP4510306A patent/JPH06510023A/ja active Pending
- 1992-04-17 WO PCT/US1992/003198 patent/WO1992018003A1/en not_active Ceased
- 1992-04-17 EP EP92917344A patent/EP0581907A1/en not_active Withdrawn
- 1992-04-17 AU AU18723/92A patent/AU668508B2/en not_active Ceased
-
1993
- 1993-10-15 NO NO933726A patent/NO933726L/no unknown
-
1994
- 1994-01-21 US US08/184,788 patent/US5442104A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU668508B2 (en) | 1996-05-09 |
| CA2108670A1 (en) | 1992-10-19 |
| NO933726D0 (no) | 1993-10-15 |
| US5442104A (en) | 1995-08-15 |
| EP0581907A4 (enExample) | 1994-04-06 |
| US5516936A (en) | 1996-05-14 |
| WO1992018003A1 (en) | 1992-10-29 |
| EP0581907A1 (en) | 1994-02-09 |
| AU1872392A (en) | 1992-11-17 |
| JPH06510023A (ja) | 1994-11-10 |
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