NO933146L - Fremgangsmåte ved undersökelse av Lupus antikoagulerende middel - Google Patents

Fremgangsmåte ved undersökelse av Lupus antikoagulerende middel

Info

Publication number
NO933146L
NO933146L NO933146A NO933146A NO933146L NO 933146 L NO933146 L NO 933146L NO 933146 A NO933146 A NO 933146A NO 933146 A NO933146 A NO 933146A NO 933146 L NO933146 L NO 933146L
Authority
NO
Norway
Prior art keywords
lupus anticoagulant
investigating
tests
oyuranusa
immunochromogenic
Prior art date
Application number
NO933146A
Other languages
English (en)
Other versions
NO933146D0 (no
Inventor
Douglas A Triplett
Kurt Stocker
Original Assignee
Pentapharm Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pentapharm Ag filed Critical Pentapharm Ag
Publication of NO933146D0 publication Critical patent/NO933146D0/no
Publication of NO933146L publication Critical patent/NO933146L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
    • C12N9/6418—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals from snakes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/4609—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates from reptiles
    • G01N2333/4613—Snake venom
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/4609—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates from reptiles
    • G01N2333/4613—Snake venom
    • G01N2333/4633—Snake venom from Echis carinatus; Ecarin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/4609—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates from reptiles
    • G01N2333/4613—Snake venom
    • G01N2333/4646—Snake venom from Oxyuran(eo)us scutellatus (Taipan snake of Elapidae family)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/04—Phospholipids, i.e. phosphoglycerides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Det ble funnet at bruken av en fosfolipidavhengig protrombinaktivator renset fra giften hos slanger tilhørende Elapidae-familien, spesielt medlemmer av Oyuranusa- og Pseudonaja-slekten, er meget anvendelig i tester for bestemmelsen av Lupus Antikoagulant. Basert på dette har flere koagulerings-, kromogene og immuno- kromogene tester blitt utviklet.
NO933146A 1992-09-04 1993-09-03 Fremgangsmåte ved undersökelse av Lupus antikoagulerende middel NO933146L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP92810679A EP0585504A1 (en) 1992-09-04 1992-09-04 Phospholipid dependant prothrombin activator and its use in lupus anticoagulant testing

Publications (2)

Publication Number Publication Date
NO933146D0 NO933146D0 (no) 1993-09-03
NO933146L true NO933146L (no) 1994-03-07

Family

ID=8211978

Family Applications (1)

Application Number Title Priority Date Filing Date
NO933146A NO933146L (no) 1992-09-04 1993-09-03 Fremgangsmåte ved undersökelse av Lupus antikoagulerende middel

Country Status (5)

Country Link
US (3) US5453370A (no)
EP (1) EP0585504A1 (no)
JP (1) JPH06199673A (no)
CA (1) CA2105213A1 (no)
NO (1) NO933146L (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972681A (en) * 1995-03-03 1999-10-26 Eisai Co., Ltd. Calcium-requiring prothrombin activator
US5763403A (en) * 1995-10-31 1998-06-09 Eric Chun-Tet Lian Snake venom lupus anticoagulant protein
US5766869A (en) * 1995-11-30 1998-06-16 Ahs Hospital Corp. Factor V ratio blood test for susceptibility to thromboembolism
US5925319A (en) * 1996-04-30 1999-07-20 Medtronic, Inc. Test cartridge for evaluating blood platelet functionality
US6489451B1 (en) * 1997-04-10 2002-12-03 Hefei-Siu-Fung Ustc Pharmaceutical Co., Ltd. Antithrombosis enzyme from the snake venom of agkistrodon acutus
DE19734648A1 (de) * 1997-08-11 1999-02-18 Dade Behring Marburg Gmbh Verwendung von Annexinen als Lupus Antikoagulans Kontrolle oder Standard in Gerinnungstesten
AUPP345098A0 (en) * 1998-05-11 1998-06-04 National Institute Of Biological Standards And Control, United Kingdom Novel anti-fibrinolytic agents
US6165795A (en) * 1998-06-25 2000-12-26 Cardiovascular Diagnostics, Inc. Methods for performing fibrinogen assays using dry chemical reagents containing ecarin and magnetic particles
US5935802A (en) * 1998-08-10 1999-08-10 Evanston Northwestern Healthcare Research Institute Method of assaying a blood sample for prothrombin
AUPP971299A0 (en) 1999-04-12 1999-05-06 South Eastern Sydney Area Health Service Procoagulant assay
JP4102062B2 (ja) * 2001-12-19 2008-06-18 野村化学株式会社 アルミニウム測定方法
US20040091952A1 (en) * 2002-07-25 2004-05-13 Sysmex Corporation Reagent kit for detecting lupus anticoagulant
US7205153B2 (en) * 2003-04-11 2007-04-17 Applied Materials, Inc. Analytical reagent for acid copper sulfate solutions
WO2005031303A2 (en) * 2003-09-22 2005-04-07 University Of North Carolina At Chapel Hill Soluble phospholipids for use in clotting factor assays
DE602005006633D1 (de) * 2004-02-06 2008-06-26 Sysmex Corp Reagenziensatz zum Nachweis von Lupus-Antikoagulant.
CN107870246B (zh) * 2010-09-20 2021-04-09 Q-塞拉有限公司 血清制备
FR2967781B1 (fr) * 2010-11-18 2019-06-28 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Determination du pouvoir thrombogene d'immunoglobulines humaines
CN107106662B (zh) * 2014-10-23 2022-03-25 Q-塞拉有限公司 改善的凝血组合物
JP6499488B2 (ja) * 2015-03-31 2019-04-10 学校法人東日本学園 凝固時間の測定方法、ループスアンチコアグラントの存否の判定方法及びループスアンチコアグラント検出用試薬キット
CN105353141B (zh) * 2015-11-17 2018-04-10 北京美创新跃医疗器械有限公司 检测试剂及其应用及含有该试剂的试剂盒
CN117825681A (zh) * 2023-12-26 2024-04-05 米度医疗科技（中山）有限公司 一种狼疮抗凝物全液体试剂及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4106992A (en) * 1971-09-24 1978-08-15 Choay S.A. Purification of urokinase
CH626917A5 (no) * 1976-08-17 1981-12-15 Pentapharm Ag
US4610879A (en) * 1984-01-06 1986-09-09 University Of Southern California Fibrinolytic enzyme from snake vernom
AT399095B (de) * 1986-03-27 1995-03-27 Vukovich Thomas Dr Verfahren zur auftrennung von proteinen mittels gradientenelution und vorrichtung zur durchführung des verfahrens
US4725673A (en) * 1986-08-29 1988-02-16 Alpha Therapeutic Corporation Plasma fraction purification using silica resin bound to a ligand
NL8902406A (nl) * 1989-09-27 1991-04-16 Hendrik Coenraad Hemker Prof D Werkwijze voor het bepalen van de endogene trombinepotentiaal van plasma, en bloed alsmede een bij deze werkwijze te gebruiken kit.
US5260060A (en) * 1991-08-09 1993-11-09 University Of Southern California Fibrinolytic enzymes
US5219995A (en) * 1992-07-14 1993-06-15 Alpha Therapeutic Corporation Plasma fraction purification
US5763403A (en) * 1995-10-31 1998-06-09 Eric Chun-Tet Lian Snake venom lupus anticoagulant protein

Also Published As

Publication number Publication date
EP0585504A1 (en) 1994-03-09
US5453370A (en) 1995-09-26
JPH06199673A (ja) 1994-07-19
US5922587A (en) 1999-07-13
NO933146D0 (no) 1993-09-03
AU669550B2 (en) 1996-06-13
US5705198A (en) 1998-01-06
AU4608793A (en) 1994-03-10
CA2105213A1 (en) 1994-03-05

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