NO925058D0 - Vevbeskyttende tokoferol-analoger - Google Patents

Vevbeskyttende tokoferol-analoger

Info

Publication number
NO925058D0
NO925058D0 NO925058A NO925058A NO925058D0 NO 925058 D0 NO925058 D0 NO 925058D0 NO 925058 A NO925058 A NO 925058A NO 925058 A NO925058 A NO 925058A NO 925058 D0 NO925058 D0 NO 925058D0
Authority
NO
Norway
Prior art keywords
alkyl
tissue protective
alkylene
tocopherol analogs
tocopherol
Prior art date
Application number
NO925058A
Other languages
English (en)
Other versions
NO925058L (no
Inventor
Johann Martin Grisar
Margaret Anne Petty
Frank Bolkenius
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of NO925058D0 publication Critical patent/NO925058D0/no
Publication of NO925058L publication Critical patent/NO925058L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Electrotherapy Devices (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pyrane Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO92925058A 1992-01-02 1992-12-30 Vevbeskyttende tokoferol-analoger NO925058L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP92400006A EP0550292A1 (en) 1992-01-02 1992-01-02 Tissue protective tocopherol analogs

Publications (2)

Publication Number Publication Date
NO925058D0 true NO925058D0 (no) 1992-12-30
NO925058L NO925058L (no) 1993-07-05

Family

ID=8211592

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92925058A NO925058L (no) 1992-01-02 1992-12-30 Vevbeskyttende tokoferol-analoger

Country Status (18)

Country Link
US (1) US5484810A (no)
EP (2) EP0550292A1 (no)
JP (1) JP3226185B2 (no)
KR (1) KR100257800B1 (no)
AT (1) ATE148884T1 (no)
AU (1) AU650585B2 (no)
CA (1) CA2084961C (no)
DE (1) DE69217473T2 (no)
DK (1) DK0550337T3 (no)
ES (1) ES2100323T3 (no)
FI (1) FI925949A (no)
GR (1) GR3023368T3 (no)
HU (1) HU215961B (no)
IL (1) IL104167A (no)
MX (1) MX9207607A (no)
NO (1) NO925058L (no)
NZ (1) NZ245501A (no)
ZA (1) ZA9210121B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5510373A (en) * 1992-04-06 1996-04-23 Merrell Pharmaceuticals Inc. Cardioprotective agents
US5721233A (en) * 1992-04-06 1998-02-24 Merrell Pharmaceuticals Inc. Derivatives of 2,3-dihydro benzofuranols
US5545660A (en) * 1992-04-07 1996-08-13 Merrell Pharmaceuticals Inc. Hydrazide derivatives of 3,4-dihydro-2H-1-benzopyrans
US5925673A (en) * 1994-12-23 1999-07-20 Alcon Laboratories, Inc. Benzofurans and benzopyrans as cytoprotective agents
JPH10168095A (ja) * 1996-12-10 1998-06-23 Cci Corp 炎症性腸疾患予防および治療剤
DE59802875D1 (de) * 1997-06-30 2002-03-14 Siemens Ag Initiatoren für die kationische Polymerisation
US6082370A (en) * 1998-02-09 2000-07-04 Rousseau Research, Inc. Cigarette with dry powered Vitamin E
CZ20002901A3 (cs) * 1998-02-09 2001-08-15 Rousseau Research, Inc. Tabákové výrobky s vitamínem E
ITTO20030140U1 (it) * 2003-09-16 2005-03-17 Interfila Srl Matita cosmetica
CA2580584C (en) * 2003-09-19 2015-07-28 Galileo Pharmaceuticals, Inc. Use of alpha-tocotrienol for treatment of mitochondrial diseases

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3553093A (en) * 1965-03-19 1971-01-05 Xerox Corp Color photoelectrophoretic imaging process
US3947473A (en) * 1972-12-22 1976-03-30 Hoffman-La Roche Inc. Antioxidant chroman compounds
DE2745305A1 (de) * 1977-10-07 1979-04-19 Bayer Ag Insektizide und akarizide mittel
US4214081A (en) * 1978-06-19 1980-07-22 E. R. Squibb & Sons, Inc. Imino containing morpholine compounds
US4153796A (en) * 1978-07-10 1979-05-08 E. R. Squibb & Sons, Inc. Hydrazino derivatives of 1H-pyrazolo(3,4-b)-pyridine-5-carboxamides
DE3010505A1 (de) * 1980-03-19 1981-10-01 Basf Ag, 6700 Ludwigshafen Chromanderivate, verfahren zu ihrer herstellung, ihre verwendung als stabilisatoren von organischen materialien sowie diese stabilisatoren enthaltende organische materialien
US4321270A (en) * 1981-01-29 1982-03-23 E. R. Squibb & Sons, Inc. Substituted chromans
US4617317A (en) * 1984-10-31 1986-10-14 Bennet Justin D Method of treating ulcerative colitis
EP0183869B1 (en) * 1984-12-06 1991-04-17 Kuraray Co., Ltd. Chroman compounds and their use
JPS61148120A (ja) * 1984-12-20 1986-07-05 Kuraray Co Ltd 鎮痛剤
JPS61148173A (ja) * 1984-12-20 1986-07-05 Kuraray Co Ltd 新規なアミン及びその塩
DE3669876D1 (de) * 1985-05-13 1990-05-03 Kuraray Co 3,4-dihydrobenzopyranderivate.
JPS62205091A (ja) * 1986-03-04 1987-09-09 Senjiyu Seiyaku Kk 新規なリン酸ジエステルならびにその塩、その製造法およびそれを含有する製剤
GB8704572D0 (en) * 1987-02-26 1987-04-01 Lundbeck & Co As H Organic compounds
CA1338012C (en) * 1987-04-27 1996-01-30 John Michael Mccall Pharmaceutically active amines
JP2855340B2 (ja) * 1988-06-10 1999-02-10 武田薬品工業株式会社 ２―置換クマラン誘導体
JPH0215778A (ja) * 1988-07-01 1990-01-19 Mitsubishi Electric Corp フアクシミリ装置
IT1229482B (it) * 1988-08-01 1991-09-03 Foscama Biomed Chim Farma Acidi (rs) 2 (2,3 diidro 5 idrossi 4,6,7 trimetilbenzofuranil) acetico e 2 (2,3 diidro 5 acilossi 4,6,7 trimetilbenzofuranil) acetici e loro esteri, utili come farmaci mucoregolatori ed antiischemici.
EP0369083A1 (en) * 1988-11-14 1990-05-23 Merrell Dow Pharmaceuticals Inc. Cardioprotective tocopherol analogs
CA2002649C (en) * 1988-11-14 2000-06-06 Margaret Petty Cardioprotective tocopherol analogs
CA2011899A1 (en) * 1989-03-13 1990-09-13 Masaaki Toda Benzopyran derivatives
IT1231341B (it) * 1989-08-18 1991-11-28 Foscama Biomed Chim Farma 2,3 diidro 5 ossi 4,6,7 trimetilbenzofurani 2 (rs) sostituiti, utili come farmaci antiossidanti con proprieta' mucoregolatrici e antiischemiche.
US4975457A (en) * 1989-09-25 1990-12-04 Merck & Co., Inc. Trans 2,3-disubstituted-2,3-dihydro-5-hydroxy-benzofurans as inhibitors of leukotriene biosynthesis

Also Published As

Publication number Publication date
CA2084961A1 (en) 1993-07-03
IL104167A0 (en) 1993-05-13
JPH0725867A (ja) 1995-01-27
MX9207607A (es) 1993-07-01
DK0550337T3 (da) 1997-03-10
IL104167A (en) 1996-12-05
FI925949A0 (fi) 1992-12-30
HUT63159A (en) 1993-07-28
AU650585B2 (en) 1994-06-23
FI925949A (fi) 1993-07-03
HU9204184D0 (en) 1993-04-28
DE69217473D1 (de) 1997-03-27
ZA9210121B (en) 1993-08-03
EP0550337A1 (en) 1993-07-07
HU215961B (hu) 1999-03-29
EP0550292A1 (en) 1993-07-07
KR100257800B1 (ko) 2000-07-01
NO925058L (no) 1993-07-05
KR930016412A (ko) 1993-08-26
NZ245501A (en) 1995-04-27
US5484810A (en) 1996-01-16
EP0550337B1 (en) 1997-02-12
DE69217473T2 (de) 1997-07-24
ATE148884T1 (de) 1997-02-15
GR3023368T3 (en) 1997-08-29
ES2100323T3 (es) 1997-06-16
JP3226185B2 (ja) 2001-11-05
AU2996692A (en) 1993-07-08
CA2084961C (en) 2003-05-27

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