NO924453D0 - Fremgangsmaate for fremstilling av et pasteurisert trombinkonsentrat - Google Patents

Fremgangsmaate for fremstilling av et pasteurisert trombinkonsentrat

Info

Publication number
NO924453D0
NO924453D0 NO924453A NO924453A NO924453D0 NO 924453 D0 NO924453 D0 NO 924453D0 NO 924453 A NO924453 A NO 924453A NO 924453 A NO924453 A NO 924453A NO 924453 D0 NO924453 D0 NO 924453D0
Authority
NO
Norway
Prior art keywords
concentrate
trombine
pasteurized
procedure
preparation
Prior art date
Application number
NO924453A
Other languages
English (en)
Other versions
NO924453L (no
NO307473B1 (no
Inventor
Hermann Karges
Horst Neumann
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of NO924453D0 publication Critical patent/NO924453D0/no
Publication of NO924453L publication Critical patent/NO924453L/no
Publication of NO307473B1 publication Critical patent/NO307473B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6429—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21005—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • External Artificial Organs (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO924453A 1991-11-19 1992-11-18 Fremgangsmõte for fremstilling av et pasteurisert trombinkonsentrat NO307473B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4137996A DE4137996A1 (de) 1991-11-19 1991-11-19 Verfahren zur herstellung eines virussicheren thrombinkonzentrates

Publications (3)

Publication Number Publication Date
NO924453D0 true NO924453D0 (no) 1992-11-18
NO924453L NO924453L (no) 1993-05-20
NO307473B1 NO307473B1 (no) 2000-04-10

Family

ID=6445112

Family Applications (1)

Application Number Title Priority Date Filing Date
NO924453A NO307473B1 (no) 1991-11-19 1992-11-18 Fremgangsmõte for fremstilling av et pasteurisert trombinkonsentrat

Country Status (12)

Country Link
US (1) US5723123A (no)
EP (1) EP0543178B1 (no)
JP (1) JPH05194261A (no)
KR (1) KR100261360B1 (no)
AT (1) ATE162218T1 (no)
AU (1) AU658238B2 (no)
CA (1) CA2083243C (no)
DE (2) DE4137996A1 (no)
DK (1) DK0543178T3 (no)
ES (1) ES2113910T3 (no)
GR (1) GR3026253T3 (no)
NO (1) NO307473B1 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT398079B (de) * 1991-11-04 1994-09-26 Immuno Ag Präparation mit thrombinaktivität sowie verfahren zu ihrer herstellung
JPH07308190A (ja) * 1994-05-18 1995-11-28 Green Cross Corp:The トロンビンの製造方法
DE4440892A1 (de) * 1994-11-17 1996-05-23 Gruenenthal Gmbh Proteine mit fibrinolytischen und gerinnungshemmenden Eigenschaften
AUPN436995A0 (en) * 1995-07-24 1995-08-17 Csl Limited Method for the production of thrombin
JP3944267B2 (ja) * 1996-08-09 2007-07-11 財団法人化学及血清療法研究所 プロトロンビンの活性化方法および該方法に基づくトロンビンの製造方法
JP2002514960A (ja) 1997-06-18 2002-05-21 コヘージョン テクノロジーズ，インコーポレイテッド トロンビンおよびミクロフィブリルコラーゲンを含む組成物、ならびにその調製および使用の方法
US6096872A (en) * 1997-10-14 2000-08-01 Ortho Diagnostic Systems, Inc. Viral clearance process
US6245548B1 (en) * 2000-03-09 2001-06-12 American National Red Cross Activation of pure prothrombin to thrombin with about 30% to about 40% sodium citrate
DE10012732A1 (de) 2000-03-18 2001-09-20 Aventis Behring Gmbh Thrombin-Zubereitungen und Verfahren zu ihrer Herstellung
AU784808B2 (en) * 2001-04-02 2006-06-29 Kedrion Melville Inc. Prion and viral clearance process
WO2003100080A2 (en) * 2002-05-23 2003-12-04 Ortho-Clinical Diagnostics, Inc. Capture, concentration and quantitation of abnormal prion protein from biological fluids using depth filtration
GB0216002D0 (en) 2002-07-10 2002-08-21 Nat Blood Authority Process and composition
AU2005229674B2 (en) * 2004-11-18 2010-11-04 Kedrion Melville Inc. Low concentration solvent/detergent process of immuneglobulin with pre-treatment

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2394566A (en) * 1942-07-13 1946-02-12 Parke Davis & Co Process for obtaining products derived from blood
US4357321A (en) * 1980-01-28 1982-11-02 Baxter Travenol Laboratories, Inc. Method and composition for treating clotting factor inhibitors
US4442655A (en) * 1981-06-25 1984-04-17 Serapharm Michael Stroetmann Fibrinogen-containing dry preparation, manufacture and use thereof
US4380511A (en) * 1981-08-12 1983-04-19 Miles Laboratories, Inc. Purification of bovine thrombin
US4965203A (en) * 1987-01-28 1990-10-23 Warner-Lambert Company Purified thrombin preparations
JPS63243032A (ja) * 1987-03-27 1988-10-07 Green Cross Corp:The トロンビンの加熱処理方法
DE3843126C3 (de) * 1988-12-22 1994-10-06 Octapharma Ag Verfahren zur Herstellung eines hochreinen Thrombinkonzentrates
US5281528A (en) * 1989-12-18 1994-01-25 Warner-Lambert Company Process for purified thromboplastin for ultra-pure thrombin preparation
US5525498A (en) * 1989-12-18 1996-06-11 Warner-Lambert Company Process for preparing an ultra-pure thrombin preparation
IE73210B1 (en) * 1990-01-24 1997-05-07 Warner Lambert Co Process for the production of thrombin and high purity thrombin preparation thereby obtained
ATE177781T1 (de) * 1990-02-20 1999-04-15 Baxter Int Gereinigtes, virusfreies menschliches thrombin
JPH0813750B2 (ja) * 1990-03-01 1996-02-14 持田製薬株式会社 経口用トロンビン製剤
US5328898A (en) * 1990-06-22 1994-07-12 Duke University Factor XIIIA fibrin binding fragments
DE69122376D1 (de) * 1991-03-28 1996-10-31 Warner Lambert Co Hochreine Thrombinzubereitung
JPH04365481A (ja) * 1991-06-11 1992-12-17 Green Cross Corp:The トロンビンの製造法
FR2679251B1 (fr) * 1991-07-18 1993-11-12 Nord Assoc Essor Transfusion San Procede de preparation d'un concentre de thrombine humaine destine a un usage therapeutique.
AT398079B (de) * 1991-11-04 1994-09-26 Immuno Ag Präparation mit thrombinaktivität sowie verfahren zu ihrer herstellung
AT397390B (de) * 1992-04-06 1994-03-25 Immuno Ag Verfahren zur spaltung von proteinen
US5428014A (en) * 1993-08-13 1995-06-27 Zymogenetics, Inc. Transglutaminase cross-linkable polypeptides and methods relating thereto
US5506127A (en) * 1994-09-21 1996-04-09 Proba; Zbigniew Therapeutic grade thrombin produced by chromatography

Also Published As

Publication number Publication date
ES2113910T3 (es) 1998-05-16
GR3026253T3 (en) 1998-05-29
EP0543178A3 (en) 1994-07-06
CA2083243C (en) 2005-02-22
EP0543178B1 (de) 1998-01-14
US5723123A (en) 1998-03-03
AU2850292A (en) 1993-05-20
ATE162218T1 (de) 1998-01-15
AU658238B2 (en) 1995-04-06
DK0543178T3 (da) 1998-09-14
JPH05194261A (ja) 1993-08-03
NO924453L (no) 1993-05-20
DE4137996A1 (de) 1993-05-27
KR930009612A (ko) 1993-06-21
CA2083243A1 (en) 1993-05-20
NO307473B1 (no) 2000-04-10
KR100261360B1 (ko) 2000-07-01
EP0543178A2 (de) 1993-05-26
DE59209133D1 (de) 1998-02-19

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