NO923947L - Smaksmaskering av ibuprofen ved fluidlagbelegning - Google Patents

Smaksmaskering av ibuprofen ved fluidlagbelegning

Info

Publication number
NO923947L
NO923947L NO92923947A NO923947A NO923947L NO 923947 L NO923947 L NO 923947L NO 92923947 A NO92923947 A NO 92923947A NO 923947 A NO923947 A NO 923947A NO 923947 L NO923947 L NO 923947L
Authority
NO
Norway
Prior art keywords
ibuprofen
taste masking
fluid coating
taste
coating
Prior art date
Application number
NO92923947A
Other languages
English (en)
Other versions
NO300758B1 (no
NO923947D0 (no
Inventor
Robert Wu-Wei Shen
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of NO923947L publication Critical patent/NO923947L/no
Publication of NO923947D0 publication Critical patent/NO923947D0/no
Publication of NO300758B1 publication Critical patent/NO300758B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO923947A 1990-04-11 1992-10-09 Fremgangsmåte for fremstilling av en smaksmaskert tablett som kan tygges og som har egenskaper med regulert frigjörelse NO300758B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50819390A 1990-04-11 1990-04-11
PCT/US1991/001089 WO1991015194A1 (en) 1990-04-11 1991-02-26 Taste masking of ibuprofen by fluid bed coating

Publications (3)

Publication Number Publication Date
NO923947L true NO923947L (no) 1992-10-09
NO923947D0 NO923947D0 (no) 1992-10-09
NO300758B1 NO300758B1 (no) 1997-07-21

Family

ID=24021750

Family Applications (1)

Application Number Title Priority Date Filing Date
NO923947A NO300758B1 (no) 1990-04-11 1992-10-09 Fremgangsmåte for fremstilling av en smaksmaskert tablett som kan tygges og som har egenskaper med regulert frigjörelse

Country Status (14)

Country Link
US (1) US5552152A (no)
EP (1) EP0524180B1 (no)
JP (1) JPH05506011A (no)
AT (1) ATE121619T1 (no)
AU (1) AU639988B2 (no)
CA (1) CA2076983A1 (no)
DE (1) DE69109282T2 (no)
DK (1) DK0524180T3 (no)
ES (1) ES2071986T3 (no)
FI (1) FI924589A (no)
HU (2) HUT64220A (no)
NO (1) NO300758B1 (no)
RU (1) RU2101010C1 (no)
WO (1) WO1991015194A1 (no)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19648576C2 (de) * 1996-11-23 1999-08-12 Lohmann Therapie Syst Lts Lutschtablette zur modifizierten Freisetzung von Wirkstoffen im Gastrointestinaltrakt
FR2766089B1 (fr) * 1997-07-21 2000-06-02 Prographarm Lab Comprime multiparticulaire perfectionne a delitement rapide
HU230154B1 (hu) * 1997-11-12 2015-09-28 Bayer Intellectual Property Gmbh Eljárás 2-es helyzetben fenil-szubszituenst hordozó imidazo-triazinon-származékok előállítására
FR2785538B1 (fr) * 1998-11-06 2004-04-09 Prographarm Laboratoires Comprime a delitement rapide perfectionne
FR2785539B1 (fr) * 1998-11-06 2004-04-09 Prographarm Laboratoires Particules enrobees d'ibuprofene cristallin granule
US6270807B1 (en) 1999-03-02 2001-08-07 L. Perrigo Company Taste-masked pharmaceutical composition
ES2234581T3 (es) 1999-04-06 2005-07-01 Ethypharm Suspension farmaceutica bebible de ibuprofeno.
EP1202716A1 (en) 1999-08-17 2002-05-08 Novartis Consumer Health S.A. Rapidly dissolving dosage form and process for making same
CA2393585C (en) 1999-12-09 2007-07-03 The Boots Company Plc Therapeutic agents
US6551617B1 (en) 2000-04-20 2003-04-22 Bristol-Myers Squibb Company Taste masking coating composition
ES2284643T3 (es) 2000-04-20 2007-11-16 Novartis Ag Composicion de revestimiento enmascarante del sabor.
JP4540295B2 (ja) * 2001-05-09 2010-09-08 バイエル・シェーリング・ファルマ・アクチェンゲゼルシャフト 2−フェニル置換イミダゾトリアジノンの新しい用途
DK1411899T3 (da) * 2001-08-01 2009-06-02 Novartis Ag Smagsmaskerende sammensætning
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
EP1476139B1 (en) 2002-02-21 2017-05-17 Valeant Pharmaceuticals Luxembourg S.à.r.l. Controlled release dosage forms
CO5400144A1 (es) * 2002-03-11 2004-05-31 Novartis Ag Compuestos organicos
DE10232113A1 (de) 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
FR2850275B1 (fr) 2003-01-24 2005-04-08 Scherer Technologies Inc R P Capsules molles a macher contenant une substance active a gout masque
JP2007031281A (ja) * 2003-06-25 2007-02-08 Kowa Co イブプロフェン含有フィルムコーティング錠剤
US20050220825A1 (en) * 2004-03-10 2005-10-06 Adrian Funke Molecular dispersions of drospirenone
DE102004023069A1 (de) * 2004-05-11 2005-12-08 Bayer Healthcare Ag Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil
DE102005001989A1 (de) * 2005-01-15 2006-07-20 Bayer Healthcare Ag Intravenöse Formulierungen von PDE-Inhibitoren
DE102005009240A1 (de) * 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften
DE102005009241A1 (de) * 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit kontrollierter Bioverfügbarkeit
SG166106A1 (en) * 2005-09-29 2010-11-29 Bayer Schering Pharma Ag Pde inhibitors and combinations thereof for the treatment of urological disorders
US20070134493A1 (en) * 2005-12-08 2007-06-14 Kanji Meghpara Compositions and capsules with stable hydrophilic layers
US7767248B2 (en) 2007-02-02 2010-08-03 Overly Iii Harry J Soft chew confectionary with high fiber and sugar content and method for making same
WO2008151734A1 (en) * 2007-06-13 2008-12-18 Bayer Schering Pharma Aktiengesellschaft Pde inhibitors for the treatment of hearing impairment
WO2009005803A1 (en) * 2007-07-01 2009-01-08 Joseph Peter Habboushe Combination tablet with chewable outer layer
US8404275B2 (en) * 2007-07-01 2013-03-26 Vitalis Llc Combination tablet with chewable outer layer
ES2363964B1 (es) 2009-11-20 2012-08-22 Gp Pharm, S.A. Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados.
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
EP2770978B1 (en) 2011-10-28 2018-01-10 Vitalis LLC Anti-flush compositions
US20130261188A1 (en) * 2012-04-02 2013-10-03 Teikoku Pharma Usa, Inc. Ibuprofen Solid Oral Dosage Composition Comprising a Methacrylic Acid Copolymer
US8993041B2 (en) 2012-10-15 2015-03-31 New Jersey Institute Of Technology Taste masked active pharmaceutical powder compositions and processes for making them
WO2014194872A1 (en) 2013-06-04 2014-12-11 Zentiva, K.S. Taste masking of water soluble drugs using poloxamers
RU2576236C1 (ru) * 2014-08-22 2016-02-27 Александр Александрович Кролевец Способ получения нанокапсул антибиотиков в агар-агаре
RU2577689C1 (ru) * 2014-08-26 2016-03-20 Александр Александрович Кролевец Способ получения нанокапсул антибиотиков в агар-агаре
RU2578408C1 (ru) * 2014-09-10 2016-03-27 Александр Александрович Кролевец Способ получения нанокапсул алкалоидов
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
CN109310646A (zh) 2016-05-05 2019-02-05 阿奎斯蒂弗医疗股份有限公司 增强递送的肾上腺素组合物
RU2688148C1 (ru) * 2016-05-10 2019-05-20 Александр Александрович Кролевец Способ получения нанокапсул экоцида в каррагинане
CN110917165A (zh) * 2019-12-26 2020-03-27 北京鑫开元医药科技有限公司海南分公司 一种布洛芬口崩片及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB971700A (en) * 1961-02-02 1964-09-30 Boots Pure Drug Co Ltd Anti-Inflammatory Agents
US4476248A (en) * 1983-02-28 1984-10-09 The Upjohn Company Crystallization of ibuprofen
US4609675A (en) * 1984-08-17 1986-09-02 The Upjohn Company Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing
DE3678644D1 (de) * 1985-08-16 1991-05-16 Procter & Gamble Wirkstoffpartikel mit sowohl kontinuierlicher als auch schneller freisetzung.
IT1214629B (it) * 1985-08-29 1990-01-18 Formenti Farmaceutici Spa Procedimento di microincapsulazione di un medicamento,medicamento cosi'preparato,e composizioni farmaceutiche che lo comprendono
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
US4835186A (en) * 1987-06-15 1989-05-30 American Home Products Corporation Spray dried ibuprofen
US5084278A (en) * 1989-06-02 1992-01-28 Nortec Development Associates, Inc. Taste-masked pharmaceutical compositions

Also Published As

Publication number Publication date
JPH05506011A (ja) 1993-09-02
FI924589A0 (fi) 1992-10-09
US5552152A (en) 1996-09-03
HU9203193D0 (en) 1992-12-28
DE69109282T2 (de) 1995-09-28
DK0524180T3 (da) 1995-09-04
HU211247A9 (en) 1995-11-28
ATE121619T1 (de) 1995-05-15
EP0524180B1 (en) 1995-04-26
HUT64220A (en) 1993-12-28
AU639988B2 (en) 1993-08-12
FI924589A (fi) 1992-10-09
RU2101010C1 (ru) 1998-01-10
NO300758B1 (no) 1997-07-21
CA2076983A1 (en) 1991-10-12
NO923947D0 (no) 1992-10-09
AU7256091A (en) 1991-10-30
EP0524180A1 (en) 1993-01-27
WO1991015194A1 (en) 1991-10-17
DE69109282D1 (de) 1995-06-01
ES2071986T3 (es) 1995-07-01

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