NO923532L - 4-(4-(4-(4-hydroksyfenyl)-piperazinyl)fenyl)-5-metyl-3h-1,2,4-triazol-3-on-derivater - Google Patents
4-(4-(4-(4-hydroksyfenyl)-piperazinyl)fenyl)-5-metyl-3h-1,2,4-triazol-3-on-derivaterInfo
- Publication number
- NO923532L NO923532L NO92923532A NO923532A NO923532L NO 923532 L NO923532 L NO 923532L NO 92923532 A NO92923532 A NO 92923532A NO 923532 A NO923532 A NO 923532A NO 923532 L NO923532 L NO 923532L
- Authority
- NO
- Norway
- Prior art keywords
- piperazinyl
- hydroxyphenyl
- phenyl
- methyl
- triazol
- Prior art date
Links
- LBXGGCVIAMMNFV-UHFFFAOYSA-N 4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-3-methyl-1h-1,2,4-triazol-5-one Chemical class CC1=NNC(=O)N1C1=CC=C(N2CCN(CC2)C=2C=CC(O)=CC=2)C=C1 LBXGGCVIAMMNFV-UHFFFAOYSA-N 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 125000004203 4-hydroxyphenyl group Chemical group [H]OC1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 125000003854 p-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1Cl 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP91202351 | 1991-09-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO923532D0 NO923532D0 (no) | 1992-09-11 |
| NO923532L true NO923532L (no) | 1993-03-15 |
Family
ID=8207873
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO92923532A NO923532L (no) | 1991-09-13 | 1992-09-11 | 4-(4-(4-(4-hydroksyfenyl)-piperazinyl)fenyl)-5-metyl-3h-1,2,4-triazol-3-on-derivater |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5254553A (es) |
| EP (1) | EP0532091A1 (es) |
| JP (1) | JPH05194436A (es) |
| KR (1) | KR930006009A (es) |
| CN (1) | CN1071420A (es) |
| AU (1) | AU652069B2 (es) |
| BG (1) | BG96815A (es) |
| CA (1) | CA2076257A1 (es) |
| FI (1) | FI923723A (es) |
| HU (1) | HUT62884A (es) |
| IL (1) | IL102863A (es) |
| MX (1) | MX9205186A (es) |
| NO (1) | NO923532L (es) |
| NZ (1) | NZ244297A (es) |
| ZA (1) | ZA926967B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW279864B (es) * | 1993-02-19 | 1996-07-01 | Janssen Pharmaceutica Nv | |
| NZ283346A (en) * | 1994-04-06 | 1997-05-26 | Janssen Pharmaceutica Nv | Ester and carbamate derivatives of di- and tri-azolones; medicaments; intermediates |
| US5571811A (en) * | 1994-07-12 | 1996-11-05 | Janssen Pharmaceutica N.V. | Sulfonamide derivatives of azolones |
| US5607932A (en) * | 1994-07-12 | 1997-03-04 | Janssen Pharmaceutica N.V. | Heterocyclic derivatives of azolones |
| US6001866A (en) * | 1995-10-05 | 1999-12-14 | Warner-Lambert Company | Method for treating and preventing inflammation and atherosclerosis |
| NZ720946A (en) | 2009-04-29 | 2017-09-29 | Amarin Pharmaceuticals Ie Ltd | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
| RS54112B1 (en) * | 2010-10-01 | 2015-12-31 | Taisho Pharmaceutical Co. Ltd | DERIVAT 1,2,4-TRIAZOLONA |
| KR101715448B1 (ko) * | 2014-07-16 | 2017-03-20 | 주식회사 큐리언트 | 염증성 질환 치료용 화합물 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1292472C (en) * | 1985-12-03 | 1991-11-26 | Alfonsus Guilielmus Knaeps | Derivatives of ¬¬4-¬4-(4-phenyl-1-piperazinyl)- phenoxymethyl|-1,3-dioxolan-2-yl|methyl|-1h-imidazoles and 1h-1,2,4-triazoles |
| US4791111A (en) * | 1985-12-23 | 1988-12-13 | Janssen Pharmaceutica, N.V. | [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles having anti-microbial properties |
| CA1331757C (en) * | 1988-02-29 | 1994-08-30 | Janssen Pharmaceutica Naamloze Vennootschap | 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols |
-
1992
- 1992-08-17 CA CA002076257A patent/CA2076257A1/en not_active Abandoned
- 1992-08-19 FI FI923723A patent/FI923723A/fi not_active Application Discontinuation
- 1992-08-19 IL IL10286392A patent/IL102863A/en not_active IP Right Cessation
- 1992-08-21 CN CN92110869A patent/CN1071420A/zh active Pending
- 1992-08-24 US US07/933,848 patent/US5254553A/en not_active Expired - Fee Related
- 1992-08-25 BG BG096815A patent/BG96815A/bg unknown
- 1992-08-27 JP JP4250403A patent/JPH05194436A/ja not_active Withdrawn
- 1992-09-03 EP EP92202663A patent/EP0532091A1/en not_active Withdrawn
- 1992-09-07 AU AU22819/92A patent/AU652069B2/en not_active Ceased
- 1992-09-09 KR KR1019920016515A patent/KR930006009A/ko not_active Application Discontinuation
- 1992-09-10 NZ NZ244297A patent/NZ244297A/en unknown
- 1992-09-11 ZA ZA926967A patent/ZA926967B/xx unknown
- 1992-09-11 NO NO92923532A patent/NO923532L/no unknown
- 1992-09-11 MX MX9205186A patent/MX9205186A/es unknown
- 1992-09-11 HU HU9202914A patent/HUT62884A/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR930006009A (ko) | 1993-04-20 |
| BG96815A (bg) | 1993-12-24 |
| JPH05194436A (ja) | 1993-08-03 |
| AU2281992A (en) | 1993-03-18 |
| AU652069B2 (en) | 1994-08-11 |
| US5254553A (en) | 1993-10-19 |
| NZ244297A (en) | 1994-03-25 |
| HU9202914D0 (en) | 1992-11-30 |
| IL102863A (en) | 1996-05-14 |
| EP0532091A1 (en) | 1993-03-17 |
| IL102863A0 (en) | 1993-01-31 |
| NO923532D0 (no) | 1992-09-11 |
| HUT62884A (en) | 1993-06-28 |
| ZA926967B (en) | 1994-03-11 |
| CA2076257A1 (en) | 1993-03-14 |
| MX9205186A (es) | 1993-03-01 |
| FI923723A (fi) | 1993-03-14 |
| FI923723A0 (fi) | 1992-08-19 |
| CN1071420A (zh) | 1993-04-28 |
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