NO920624L - Reagens for paavisning av fibrinolytisk aktivitet - Google Patents

Reagens for paavisning av fibrinolytisk aktivitet

Info

Publication number
NO920624L
NO920624L NO92920624A NO920624A NO920624L NO 920624 L NO920624 L NO 920624L NO 92920624 A NO92920624 A NO 92920624A NO 920624 A NO920624 A NO 920624A NO 920624 L NO920624 L NO 920624L
Authority
NO
Norway
Prior art keywords
antibody
fibrinolytic enzyme
fibrinolytic
reagent
determination
Prior art date
Application number
NO92920624A
Other languages
English (en)
Other versions
NO920624D0 (no
Inventor
Johan Selmer
Niels Tromholt
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO920624L publication Critical patent/NO920624L/no
Publication of NO920624D0 publication Critical patent/NO920624D0/no

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/972—Plasminogen activators
    • G01N2333/9726—Tissue plasminogen activator

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Et diagnostisk reagens for påvisning in vivo av øket fri- gjøring av et fibrinolytisk enzym eller øket fibrinolytisk aktivitet i et menneske eller dyr omfatter et antistoff som er reaktivt med et fibrinolytisk enzym, eller et fragment av anti- stoffet, merket med en substans som gjør mulig påvisning in vivo av binding av antistoffet til det fibrinolytiske enzym. Ved en utførelsesform er øket fjerning av antistoffet tilveiebrakt ved etterfølgende administrering av det fibrinolytiske enzym med hvilket antistoffet er reaktivt. Det fibrinolytiske enzym er fortrinnsvis t-PA.
NO920624A 1989-08-18 1992-02-17 Reagens for paavisning av fibrinolytisk aktivitet NO920624D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK408289A DK408289D0 (da) 1989-08-18 1989-08-18 Diagnostisk reagens
PCT/DK1990/000210 WO1991002546A1 (en) 1989-08-18 1990-08-16 A reagent for the detection of fibrinolytic activity

Publications (2)

Publication Number Publication Date
NO920624L true NO920624L (no) 1992-02-17
NO920624D0 NO920624D0 (no) 1992-02-17

Family

ID=8129992

Family Applications (1)

Application Number Title Priority Date Filing Date
NO920624A NO920624D0 (no) 1989-08-18 1992-02-17 Reagens for paavisning av fibrinolytisk aktivitet

Country Status (18)

Country Link
US (1) US5165912A (no)
EP (1) EP0487594B1 (no)
JP (1) JPH04507254A (no)
KR (1) KR920703120A (no)
AT (1) ATE92770T1 (no)
AU (1) AU639940B2 (no)
CA (1) CA2065147A1 (no)
CZ (1) CZ280904B6 (no)
DD (1) DD297064A5 (no)
DE (1) DE69002769T2 (no)
DK (2) DK408289D0 (no)
ES (1) ES2058931T3 (no)
FI (1) FI920669A0 (no)
IE (1) IE65525B1 (no)
IL (1) IL95407A (no)
NO (1) NO920624D0 (no)
NZ (1) NZ234937A (no)
WO (1) WO1991002546A1 (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6355243B1 (en) * 1999-11-13 2002-03-12 Bayer Corporation Method of thrombolysis by local delivery of active plasmin
US7544500B2 (en) * 1999-11-13 2009-06-09 Talecris Biotherapeutics, Inc. Process for the production of a reversibly inactive acidified plasmin composition
US6964764B2 (en) * 1999-11-13 2005-11-15 Talecris Biotherapeutics, Inc. Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin
US20080167544A1 (en) * 2006-12-01 2008-07-10 Cold Spring Diagnostics, Inc. Compositions And Methods For Locating An Internal Bleeding Site
US8617863B2 (en) * 2008-06-04 2013-12-31 Grifols Therapeutics Inc. Composition, method, and kit for preparing plasmin
PT2403865E (pt) 2009-03-03 2015-11-18 Grifols Therapeutics Inc Métodos de preparação de plasminogénio

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61501321A (ja) * 1984-01-23 1986-07-03 インスティテュト・フォ−・エネジテクニク たんぱく様物質標識用テクネチウム９９ｍ組成物およびその使用方法
US4659839A (en) * 1984-10-10 1987-04-21 Mallinckrodt, Inc. Coupling agents for radiolabeled antibody fragments
CA1285223C (en) * 1986-11-10 1991-06-25 New England Deaconess Hospital Detection of vascular disease

Also Published As

Publication number Publication date
CZ280904B6 (cs) 1996-05-15
KR920703120A (ko) 1992-12-17
JPH04507254A (ja) 1992-12-17
AU6285990A (en) 1991-04-03
ATE92770T1 (de) 1993-08-15
EP0487594A1 (en) 1992-06-03
CA2065147A1 (en) 1991-02-19
NZ234937A (en) 1991-11-26
IE902977A1 (en) 1991-02-27
US5165912A (en) 1992-11-24
DK408289D0 (da) 1989-08-18
NO920624D0 (no) 1992-02-17
ES2058931T3 (es) 1994-11-01
IL95407A0 (en) 1991-06-30
EP0487594B1 (en) 1993-08-11
AU639940B2 (en) 1993-08-12
FI920669A0 (fi) 1992-02-17
CZ404790A3 (en) 1996-01-17
DK0487594T3 (da) 1994-01-03
DD297064A5 (de) 1992-01-02
IE65525B1 (en) 1995-11-01
DE69002769T2 (de) 1993-12-02
IL95407A (en) 1994-07-31
WO1991002546A1 (en) 1991-03-07
DE69002769D1 (de) 1993-09-16

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