GB1485340A - Process for the determination of thyroid hormone - Google Patents
Process for the determination of thyroid hormoneInfo
- Publication number
- GB1485340A GB1485340A GB3125775A GB3125775A GB1485340A GB 1485340 A GB1485340 A GB 1485340A GB 3125775 A GB3125775 A GB 3125775A GB 3125775 A GB3125775 A GB 3125775A GB 1485340 A GB1485340 A GB 1485340A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pepsin
- thyroid hormone
- determination
- sample
- acid hydrochloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
1485340 Determination of thyroid content utilizing pepsin digestion CENTER FOR LABORATORY MEDICINE 25 July 1975 31257/75 Heading G1B A process for the determination of thyroid hormone content of a blood serum sample comprises mixing with a sample of blood serum pepsin at a pH of about 1À0, incubating the sample for a period of time and at a temperature sufficient to allow the pepsin to digest the thyroid hormone binding protein in the serum, adjusting the mixture to a pH at which the pepsin is inactive and assaying the mixture for the released thyroid hormone. The pepsin may be in the form of an aqueous solution containing 6À0N.HCl or alternatively glycine hydrochloride, glutamic acid hydrochloride or aspartic acid hydrochloride, or pepsin and an acid may be included in a tablet comprising pepsin, glutamic acid hydrochloride and lactose. A process utilizing the invention in radioimmuno assay of I-125-thyroxine is described.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3125775A GB1485340A (en) | 1975-07-25 | 1975-07-25 | Process for the determination of thyroid hormone |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3125775A GB1485340A (en) | 1975-07-25 | 1975-07-25 | Process for the determination of thyroid hormone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1485340A true GB1485340A (en) | 1977-09-08 |
Family
ID=10320391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3125775A Expired GB1485340A (en) | 1975-07-25 | 1975-07-25 | Process for the determination of thyroid hormone |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1485340A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA007615B1 (en) * | 2005-12-16 | 2006-12-29 | Некоммерческое Учреждение "Научно-Исследовательский Институт Цитохимии И Молекулярной Фармакологии" | A mixture of medicament quality control “0.1 g sublingual glycine tablets” and method for preparing thereof |
-
1975
- 1975-07-25 GB GB3125775A patent/GB1485340A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA007615B1 (en) * | 2005-12-16 | 2006-12-29 | Некоммерческое Учреждение "Научно-Исследовательский Институт Цитохимии И Молекулярной Фармакологии" | A mixture of medicament quality control “0.1 g sublingual glycine tablets” and method for preparing thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CSNS | Application of which complete specification have been accepted and published, but patent is not sealed |