NO914490L - Analogifremgangsmaate for fremstilling av terapeutisk virksomme tricykliske forbindelser - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk virksomme tricykliske forbindelser

Info

Publication number
NO914490L
NO914490L NO91914490A NO914490A NO914490L NO 914490 L NO914490 L NO 914490L NO 91914490 A NO91914490 A NO 91914490A NO 914490 A NO914490 A NO 914490A NO 914490 L NO914490 L NO 914490L
Authority
NO
Norway
Prior art keywords
preparation
therapeutically effective
tricyclic compounds
analogy procedure
effective tricyclic
Prior art date
Application number
NO91914490A
Other languages
English (en)
Norwegian (no)
Other versions
NO914490D0 (no
Inventor
Jacob Berger
Robin D Clark
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of NO914490D0 publication Critical patent/NO914490D0/no
Publication of NO914490L publication Critical patent/NO914490L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO91914490A 1990-11-16 1991-11-15 Analogifremgangsmaate for fremstilling av terapeutisk virksomme tricykliske forbindelser NO914490L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/614,326 US5189041A (en) 1990-11-16 1990-11-16 Tricyclic 5-ht3 receptor antagonists

Publications (2)

Publication Number Publication Date
NO914490D0 NO914490D0 (no) 1991-11-15
NO914490L true NO914490L (no) 1992-05-18

Family

ID=24460766

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91914490A NO914490L (no) 1990-11-16 1991-11-15 Analogifremgangsmaate for fremstilling av terapeutisk virksomme tricykliske forbindelser

Country Status (17)

Country Link
US (1) US5189041A (OSRAM)
EP (1) EP0485962A3 (OSRAM)
JP (1) JPH04283587A (OSRAM)
KR (1) KR920009828A (OSRAM)
AU (1) AU8785291A (OSRAM)
CA (1) CA2055680A1 (OSRAM)
FI (1) FI915400A7 (OSRAM)
HU (1) HUT59406A (OSRAM)
IE (1) IE913987A1 (OSRAM)
IL (1) IL100061A0 (OSRAM)
IT (1) IT1250049B (OSRAM)
MX (1) MX9102076A (OSRAM)
NO (1) NO914490L (OSRAM)
PL (1) PL292419A1 (OSRAM)
PT (1) PT99518A (OSRAM)
TW (1) TW208007B (OSRAM)
ZA (1) ZA919078B (OSRAM)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR970007917B1 (ko) * 1989-11-28 1997-05-17 신텍스 인크. 신규 삼환식 화합물
JP2831467B2 (ja) * 1992-03-12 1998-12-02 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー ５ｈｔ▲下４▼−受容体アンタゴニストとしての縮合インドール誘導体
US5852014A (en) * 1992-03-12 1998-12-22 Smithkline Beecham P.L.C. Condensed indole derivatives as 5HT4 -receptor antagonists
MX9305947A (es) * 1992-09-29 1994-06-30 Smithkline Beecham Plc Compuestos antagonistas del receptor 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que las contienen.
ES2113568T3 (es) * 1993-04-27 1998-05-01 Solvay Fluor & Derivate Procedimiento para la preparacion de esteres de acidos carboxilicos a partir de halogenuros de acidos carboxilicos y alcoholes.
US6489355B2 (en) * 1993-12-01 2002-12-03 Eli Lilly And Company Methods of inhibiting the effects of amyloidogenic proteins
US5723103A (en) * 1994-12-09 1998-03-03 Vanderbilt University Substituted benzamides and radioligand analogs and methods of use
IT1303123B1 (it) 1998-10-13 2000-10-30 Rotta Research Lab Derivati basici di benz(e)isoindol-1-oni e pirrolo(3,4-c)chinolin-1-oni ad attivita' 5ht3 antagonista, loro preparazione ed
CA2399791A1 (en) * 2000-02-11 2001-08-16 Bristol-Myers Squibb Company Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators in treating respiratory and non-respiratory diseases
EP1284732A2 (en) * 2000-05-18 2003-02-26 Glaxo Group Limited Method for treating functional dyspepsia using alosetron
AR036041A1 (es) 2001-06-12 2004-08-04 Upjohn Co Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen
AR036040A1 (es) 2001-06-12 2004-08-04 Upjohn Co Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen
EP1442037A1 (en) 2001-11-09 2004-08-04 PHARMACIA & UPJOHN COMPANY Azabicyclic-phenyl-fused-heterocyclic compounds and their use as alpha7 nachr ligands
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
DE10234424A1 (de) * 2002-07-29 2004-02-12 Bayer Ag Benzothiophen-, Benzofuran- und Indolharnstoffe
TWI355936B (en) 2003-02-18 2012-01-11 Helsinn Healthcare Sa Uses of palonosetron hydrochloride
ITMI20031467A1 (it) * 2003-07-18 2005-01-19 Acraf Farmaco attivo nel dolore neuropatico
HUE037938T2 (hu) 2008-11-19 2018-09-28 Forum Pharmaceuticals Inc Skizofrénia negatív tüneteinek kezelése (R)-7-klór-N-(kinuklidin-3-il)benzo[b]tiofén-2-karboxamiddal és ennek gyógyszerészetileg elfogadható sójával
US9145396B2 (en) 2008-12-01 2015-09-29 Targacept, Inc. Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3ylvinyl)pyrimidine
ES2570657T3 (es) 2010-05-17 2016-05-19 Forum Pharmaceuticals Inc Una forma cristalina de hidrocloruro de (R)-7-cloro-n-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida monohidrato
WO2013169646A1 (en) 2012-05-08 2013-11-14 Envivo Pharmaceuticals, Inc. Methods of maintaining, treating or improving cognitive function

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2121394A1 (fr) * 1971-01-08 1972-08-25 Anvar Procédé d'obtention de dérivés d'acides indole carboxyliques et produits préparables par ce procédé.
JPS5337696A (en) * 1976-08-26 1978-04-06 Omnium Chimique Sa Hexahydrocantinonee6 derivative
FR2475394A1 (fr) * 1980-02-12 1981-08-14 Synthelabo Compositions pharmaceutiques contenant l'hexahydro-1, 2, 3, 3a, 4, 5, 6h indolo (3, 2, 1 - d. e) (1, 5) naphtyridinone - 6
FI74707C (fi) * 1982-06-29 1988-03-10 Sandoz Ag Foerfarande foer framstaellning av terapeutiskt anvaendbara alkylenoeverbryggade piperidylestrar eller -amider av bicykliska karboxylsyror.
GB8623142D0 (en) * 1986-09-26 1986-10-29 Beecham Group Plc Compounds
JP2765845B2 (ja) * 1986-11-21 1998-06-18 グラクソ、グループ、リミテッド 中止症候群の予防の治療薬
PH25493A (en) * 1987-09-03 1991-07-24 Glaxo Group Ltd 2,3,4,5-tetrahydro-2-£(imidazol-(or-5)-yl)methyl-ih-pyrido£4,3-b|indol-1-ones , derivatives having 5-ht antagonist activity 3
DE3810552A1 (de) * 1988-03-29 1989-10-19 Sandoz Ag Ester und amide von indol-, benzo(b)thiopen-, benzo(b)furancarbonsaeuren oder 4-amino-2-methoxy-benzolsaeuren mit n-heterocyclischen oder n-heterobicyclischen alkoholen oder aminen, verfahren zu deren herstellung sie enthaltende pharmazeutische zusammensetzungen sowie applikator zur verabreichung derselben
JPH02167280A (ja) * 1988-08-15 1990-06-27 Glaxo Group Ltd ラクタム誘導体
EP0377238A1 (en) * 1988-12-22 1990-07-11 Duphar International Research B.V New annelated indolo (3,2-c)-lactams
GB8904551D0 (en) * 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical compounds
EP0392663A1 (en) * 1989-03-13 1990-10-17 Ono Pharmaceutical Co., Ltd. Carboline derivative as a 5-HT3 receptor antagonist
JPH02290878A (ja) * 1989-04-28 1990-11-30 Ono Pharmaceut Co Ltd ベンゾチエノ（フロ）ピリジン誘導体

Also Published As

Publication number Publication date
PT99518A (pt) 1992-09-30
FI915400A0 (fi) 1991-11-15
CA2055680A1 (en) 1992-05-17
IE913987A1 (en) 1992-05-20
KR920009828A (ko) 1992-06-25
ITTO910865A1 (it) 1993-05-12
MX9102076A (es) 1992-07-08
IL100061A0 (en) 1992-08-18
US5189041A (en) 1993-02-23
TW208007B (OSRAM) 1993-06-21
PL292419A1 (en) 1993-04-05
NO914490D0 (no) 1991-11-15
ZA919078B (en) 1993-05-17
EP0485962A2 (en) 1992-05-20
HU913579D0 (en) 1992-01-28
ITTO910865A0 (it) 1991-11-12
FI915400A7 (fi) 1992-05-17
AU8785291A (en) 1992-05-21
IT1250049B (it) 1995-03-30
EP0485962A3 (en) 1992-07-29
JPH04283587A (ja) 1992-10-08
HUT59406A (en) 1992-05-28

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