NO914250L - Fremgangsmaate for fremstilling av piperazinderivater - Google Patents

Fremgangsmaate for fremstilling av piperazinderivater

Info

Publication number
NO914250L
NO914250L NO91914250A NO914250A NO914250L NO 914250 L NO914250 L NO 914250L NO 91914250 A NO91914250 A NO 91914250A NO 914250 A NO914250 A NO 914250A NO 914250 L NO914250 L NO 914250L
Authority
NO
Norway
Prior art keywords
procedure
piperazine derivatives
preparing piperazine
preparing
derivatives
Prior art date
Application number
NO91914250A
Other languages
English (en)
Norwegian (no)
Other versions
NO914250D0 (no
Inventor
Eva Agai
Tibor Gizur
Kalman Harsanyi
Ferenc Trischler
Aniko Demeter
Attila Csehi
Eva Vajda
Gyoergyi Szabo
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of NO914250D0 publication Critical patent/NO914250D0/no
Publication of NO914250L publication Critical patent/NO914250L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO91914250A 1990-10-31 1991-10-30 Fremgangsmaate for fremstilling av piperazinderivater NO914250L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU906953A HU209723B (en) 1990-10-31 1990-10-31 Process for producing of piperazine derivatives

Publications (2)

Publication Number Publication Date
NO914250D0 NO914250D0 (no) 1991-10-30
NO914250L true NO914250L (no) 1992-05-04

Family

ID=10972063

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91914250A NO914250L (no) 1990-10-31 1991-10-30 Fremgangsmaate for fremstilling av piperazinderivater

Country Status (11)

Country Link
EP (1) EP0483932A1 (pt)
JP (1) JPH04264078A (pt)
KR (1) KR920008018A (pt)
AU (1) AU8683091A (pt)
CA (1) CA2054544A1 (pt)
CS (1) CS329491A3 (pt)
HU (1) HU209723B (pt)
NO (1) NO914250L (pt)
PL (1) PL292227A1 (pt)
PT (1) PT99368A (pt)
ZA (1) ZA918636B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0585500A1 (en) * 1992-09-04 1994-03-09 Merrell Dow Pharmaceuticals Inc. Diaryl piperazineacetamides as antimuscarinic agents
WO2001062749A1 (en) 2000-02-22 2001-08-30 Cv Therapeutics, Inc. Substituted piperazine compounds
WO2001062711A2 (en) 2000-02-22 2001-08-30 Cv Therapeutics, Inc. Substituted alkylene diamine compounds
US6677336B2 (en) 2000-02-22 2004-01-13 Cv Therapeutics, Inc. Substituted piperazine compounds
US6451798B2 (en) 2000-02-22 2002-09-17 Cv Therapeutics, Inc. Substituted alkyl piperazine derivatives
MXPA02008213A (es) * 2000-02-22 2004-04-05 Cv Therapeutics Inc Compuestos piperazina sustituidos.
US6552023B2 (en) 2000-02-22 2003-04-22 Cv Therapeutics, Inc. Aralkyl substituted piperazine compounds
KR100797835B1 (ko) * 2001-08-13 2008-01-24 주식회사 포스코 핀치롤의 이물질 제거장치
WO2004063180A1 (en) 2003-01-03 2004-07-29 Cv Therapeutics, Inc. Substituted heterocyclic compounds
CA2530376A1 (en) 2003-06-23 2005-01-06 Cv Therapeutics, Inc. Urea derivatives of piperazines and piperidines as fatty acid oxidation inhibitors
EP1723129A1 (en) * 2003-12-18 2006-11-22 Cv Therapeutics, Inc. 1-akan-2-ol substituted piperazine and piperidine compounds
WO2006008753A1 (en) * 2004-07-19 2006-01-26 Unichem Laboratories Limited Crystalline and amorphous form of ranolazine and the process for manufacturing them
WO2008047388A2 (en) * 2006-10-20 2008-04-24 Ind-Swift Laboratories Limited Improved process for the preparation of ranolazine
WO2008139492A2 (en) * 2007-05-15 2008-11-20 Natco Pharma Limited A process for the preparation of highly pure ranolazine base
US20110300218A1 (en) * 2008-09-09 2011-12-08 Actavis Group Ptc Ehf Novel solid state forms of ranolazine salts
US20110223213A1 (en) * 2008-10-15 2011-09-15 Actavis Group Ptc Ehf Highly pure ranolazine or a pharmaceutically acceptable salt thereof
WO2010097805A1 (en) 2009-02-24 2010-09-02 Lupin Limited A process for the preparation of ranolazine
WO2016142819A2 (en) 2015-03-10 2016-09-15 Unichem Laboratories Limited Novel process for the preparation of ranolazine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB662283A (en) * 1948-08-02 1951-12-05 Rhone Poulenc Sa Improvements in or relating to piperazine compounds
US4567264A (en) * 1983-05-18 1986-01-28 Syntex (U.S.A.) Inc. Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry

Also Published As

Publication number Publication date
HU906953D0 (en) 1991-05-28
CA2054544A1 (en) 1992-05-01
NO914250D0 (no) 1991-10-30
AU8683091A (en) 1992-05-07
CS329491A3 (en) 1992-05-13
JPH04264078A (ja) 1992-09-18
HU209723B (en) 1994-10-28
PL292227A1 (en) 1992-06-26
PT99368A (pt) 1992-09-30
HUT62278A (en) 1993-04-28
ZA918636B (en) 1992-08-26
KR920008018A (ko) 1992-05-27
EP0483932A1 (en) 1992-05-06

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