NO913612L - Nye skualen-syntetaseinhibitorer. - Google Patents

Nye skualen-syntetaseinhibitorer.

Info

Publication number
NO913612L
NO913612L NO91913612A NO913612A NO913612L NO 913612 L NO913612 L NO 913612L NO 91913612 A NO91913612 A NO 91913612A NO 913612 A NO913612 A NO 913612A NO 913612 L NO913612 L NO 913612L
Authority
NO
Norway
Prior art keywords
synthetase
new school
phase inhibitors
inhibitors
phase
Prior art date
Application number
NO91913612A
Other languages
English (en)
Norwegian (no)
Other versions
NO913612D0 (no
Inventor
James D Bergstrom
Claude Dufresne
Leeyuan Huang
Mary Nallin
Janet C Onishi
Gerald F Bills
Maria T Diez
Kenneth F Bartizal
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/582,452 external-priority patent/US5102907A/en
Priority claimed from US07/582,303 external-priority patent/US5026554A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NO913612D0 publication Critical patent/NO913612D0/no
Publication of NO913612L publication Critical patent/NO913612L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NO91913612A 1990-09-13 1991-09-12 Nye skualen-syntetaseinhibitorer. NO913612L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58245390A 1990-09-13 1990-09-13
US07/582,452 US5102907A (en) 1990-09-13 1990-09-13 Novel squalene synthetase inhibitors
US07/582,303 US5026554A (en) 1990-09-13 1990-09-13 Method of inhibiting fungal growth using squalene synthetase inhibitors

Publications (2)

Publication Number Publication Date
NO913612D0 NO913612D0 (no) 1991-09-12
NO913612L true NO913612L (no) 1992-03-16

Family

ID=27416377

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91913612A NO913612L (no) 1990-09-13 1991-09-12 Nye skualen-syntetaseinhibitorer.

Country Status (12)

Country Link
EP (1) EP0475706A1 (pt)
JP (1) JPH04360889A (pt)
KR (1) KR920006360A (pt)
AU (1) AU640520B2 (pt)
CA (1) CA2050739A1 (pt)
FI (1) FI914295A7 (pt)
IE (1) IE913221A1 (pt)
IL (1) IL99415A0 (pt)
MX (1) MX9100998A (pt)
NO (1) NO913612L (pt)
NZ (1) NZ239663A (pt)
PT (1) PT98901A (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL97251A0 (en) * 1990-03-21 1992-05-25 Merck & Co Inc Antihypercholesterolemic 2,8-dioxabicyclo(3,2,1)octane derivatives,their preparation and pharmaceutical compositions containing them
YU49292A (sh) * 1991-05-10 1995-01-31 Merck And Co.Inc. Nova jedinjenja koja snižavaju holesterol
US5256689A (en) * 1991-05-10 1993-10-26 Merck & Co., Inc. Cholesterol lowering compounds
MX9202156A (es) * 1991-05-10 1993-08-01 Merck & Co Inc Novedosos compuestos para reducir el colesterol.
AU2230292A (en) * 1991-07-16 1993-02-23 Glaxo Group Limited Cyclic ketal derivatives
EP0526936A3 (en) * 1991-08-02 1993-05-05 Merck & Co. Inc. Cholesterol-lowering agents
US5364948A (en) * 1991-08-02 1994-11-15 Merck & Co., Inc. Biologically active compounds isolated from aerobic fermentation of Trichoderma viride
GB2261373A (en) * 1991-11-15 1993-05-19 Merck & Co Inc Inhibitors of farnesyl protein transferase as anti-cancer agents
US5294627A (en) * 1992-08-27 1994-03-15 Merck & Co., Inc. Directed biosynthesis of biologically active compounds
US5726306A (en) * 1992-04-20 1998-03-10 Takeda Chemical Industries, Ltd. 4,1-benzoxazepin derivatives and their use
DE69332792T2 (de) * 1992-04-20 2004-01-15 Takeda Chemical Industries Ltd 4,1-Benzoxazepinderivate als Squalen-Synthetase Inhibitoren und ihre Verwendung zur Behandlung von Hypercholesterämie und als Fungizide
EP0568946A1 (en) * 1992-05-08 1993-11-10 Takeda Chemical Industries, Ltd. Compound TAN-1607A, its derivatives, their production, and use thereof
US5283256A (en) * 1992-07-22 1994-02-01 Merck & Co., Inc. Cholesterol-lowering agents
US5310949A (en) * 1992-09-02 1994-05-10 Merck & Co., Inc. Cholesterol lowering compounds
US5322855A (en) * 1992-10-19 1994-06-21 Merck & Co., Inc. Cholesterol lowering compounds
US5447717A (en) * 1993-02-25 1995-09-05 Merck & Co., Inc. Cholesterol-lowering agents
AU678503B2 (en) * 1993-09-24 1997-05-29 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds and their use as squalene synthetase inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL97251A0 (en) * 1990-03-21 1992-05-25 Merck & Co Inc Antihypercholesterolemic 2,8-dioxabicyclo(3,2,1)octane derivatives,their preparation and pharmaceutical compositions containing them
DE69214127T2 (de) * 1991-01-09 1997-02-13 Glaxo Group Ltd Überbrückte, cyclische ketale
GB9100431D0 (en) * 1991-01-09 1991-02-20 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
IE913221A1 (en) 1992-02-25
FI914295A0 (fi) 1991-09-12
MX9100998A (es) 1992-05-04
JPH04360889A (ja) 1992-12-14
AU640520B2 (en) 1993-08-26
CA2050739A1 (en) 1992-03-14
AU8386891A (en) 1992-03-19
NO913612D0 (no) 1991-09-12
KR920006360A (ko) 1992-04-27
FI914295L (fi) 1992-03-14
EP0475706A1 (en) 1992-03-18
IL99415A0 (en) 1992-08-18
NZ239663A (en) 1993-07-27
PT98901A (pt) 1992-08-31
FI914295A7 (fi) 1992-03-14

Similar Documents

Publication Publication Date Title
NO913612L (no) Nye skualen-syntetaseinhibitorer.
MX9205145A (es) Nuevos derivados heterociclicos.
FI912623A7 (fi) Farmakologiskt aktiva foereningar med verkan pao det centrala nervsystemet.
NO933471D0 (no) Nye ikke-antikoagulerende heparinderivater
FI911353A7 (fi) Uusia skvaleenisyntetaasin inhibiittoreita
DE69204335D1 (de) Elektrostatische Halteplatte.
FI920564L (fi) Heterocykliska kvaevefoereningar.
NO930156L (no) Nye oksazolylderivater
DE68901091D1 (de) Hmg-coa-reduktaseinhibitoren.
FI920121L (fi) Foerfarande foer framstaellning av heterocykliska hydroxylaminer.
FI921230A0 (fi) Floedesrulltransportoer utan floedes- tryck.
FI912622L (fi) Farmakologiskt aktiva foereningar med verkan pao det centrala nervsystemet.
NO922243L (no) Nye cefem-forbindelser
FI890827A7 (fi) Lysyloxidas-inhibitorer.
NO904740D0 (no) Stativ for filmspole.
DE69200295D1 (de) Bandhalter.
FI922348A0 (fi) Persondator med alternativ system- styrenhet.
NO923232D0 (no) Nye herbicider
NO924900L (no) Nye tiazoler
DE69205452D1 (de) Filmhalterung.
DE69215128D1 (de) Spurverfolgungseinstellung
DK186791D0 (da) Nye enzymer
NO952937D0 (no) Nye substituerte tiosemikarbazon derivater
ATA145191A (de) Gleisstopfmaschine
FI914621A7 (fi) Heterocykliska syror.