NO913158L - 6-substituert-heksahydrobenz(cd)indoler og fremgangsmaate for deres fremstilling. - Google Patents

6-substituert-heksahydrobenz(cd)indoler og fremgangsmaate for deres fremstilling.

Info

Publication number
NO913158L
NO913158L NO91913158A NO913158A NO913158L NO 913158 L NO913158 L NO 913158L NO 91913158 A NO91913158 A NO 91913158A NO 913158 A NO913158 A NO 913158A NO 913158 L NO913158 L NO 913158L
Authority
NO
Norway
Prior art keywords
hydrobenz
indoles
procedures
preparation
hex
Prior art date
Application number
NO91913158A
Other languages
English (en)
Other versions
NO913158D0 (no
NO176019C (no
NO176019B (no
Inventor
Michael Edward Flaugh
Michael John Martinelli
John Mehnert Schaus
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO913158D0 publication Critical patent/NO913158D0/no
Publication of NO913158L publication Critical patent/NO913158L/no
Publication of NO176019B publication Critical patent/NO176019B/no
Publication of NO176019C publication Critical patent/NO176019C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Addiction (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO913158A 1990-08-15 1991-08-13 Analogifremgangsmåte for fremstilling av terapeutisk aktive 6-substituert-heksahydrobenz(cd)indoler samt mellomprodukter for disse NO176019C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56798790A 1990-08-15 1990-08-15
US07/725,177 US5229410A (en) 1990-08-15 1991-07-03 6-substituted-hexahydrobenz[cd]indoles

Publications (4)

Publication Number Publication Date
NO913158D0 NO913158D0 (no) 1991-08-13
NO913158L true NO913158L (no) 1992-02-17
NO176019B NO176019B (no) 1994-10-10
NO176019C NO176019C (no) 1995-01-18

Family

ID=27074631

Family Applications (1)

Application Number Title Priority Date Filing Date
NO913158A NO176019C (no) 1990-08-15 1991-08-13 Analogifremgangsmåte for fremstilling av terapeutisk aktive 6-substituert-heksahydrobenz(cd)indoler samt mellomprodukter for disse

Country Status (17)

Country Link
US (1) US5229410A (no)
EP (1) EP0471569A1 (no)
JP (1) JPH04230664A (no)
KR (1) KR920004346A (no)
CN (1) CN1058962A (no)
AU (1) AU648331B2 (no)
BR (1) BR9103479A (no)
CS (1) CS249591A3 (no)
FI (1) FI913834A (no)
HU (1) HUT59095A (no)
IE (1) IE912879A1 (no)
IL (1) IL99149A0 (no)
MX (1) MX9100644A (no)
NO (1) NO176019C (no)
NZ (1) NZ239334A (no)
PT (1) PT98639A (no)
YU (1) YU140391A (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204340A (en) * 1989-04-11 1993-04-20 Eli Lilly And Company Tetrahydrobenz(c,d)indole serotonin agonists
DK0471515T3 (da) * 1990-08-15 1997-07-21 Lilly Co Eli Ringsubstituerede 2-amino-1,2,3,4-tetrahydronphtalener, 3-aminochromaner og 3-aminothiochromaner
US5641794A (en) * 1991-03-28 1997-06-24 Eli Lilly Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles
US5347013A (en) * 1991-03-28 1994-09-13 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles
US5364856A (en) * 1991-03-28 1994-11-15 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
US5292766A (en) * 1992-03-25 1994-03-08 Eli Lilly And Company Method for improving primary memory and/or learning
US5385928A (en) * 1994-05-18 1995-01-31 Eli Lilly And Company Tetrahydrobenz [CD] indazoles, compositions and use
WO1998046353A1 (en) 1997-04-15 1998-10-22 Massachusetts Institute Of Technology Synthesis and application of vapor grafted porous materials
KR20050043568A (ko) * 2003-11-06 2005-05-11 김상현 두족류 연체동물 포획용 분할형 인공패각

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE517732C (de) * 1927-10-27 1931-02-09 Then Rudolf Faerbekufe mit einem drehbaren, trommelartigen Rahmen fuer die auf aus-wechselbaren Faerbestoecken aufgehaengten Waren, insbesondere Struempfe
BE542760A (no) * 1954-11-12
US3194811A (en) * 1963-09-05 1965-07-13 Merck & Co Inc Aroyl-benzindolyl acids
BE755270A (fr) * 1969-08-27 1971-02-25 Sandoz Sa Nouveaux derives du benzo(cd)indole, leur preparation et medicaments contenant ces derives
FI206974A (no) * 1973-07-16 1975-01-17 Sandoz Ag
US4110339A (en) * 1977-11-25 1978-08-29 Eli Lilly And Company 4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole
FR2522658A1 (fr) * 1982-03-05 1983-09-09 Roussel Uclaf Application a titre de medicaments de derives du trans 4-amino benz (c,d) indol-5-ol ainsi que de leurs sels, compositions les renfermant, nouveaux derives et leur procede de preparation
DE3346573A1 (de) * 1983-12-23 1985-07-04 Troponwerke GmbH & Co KG, 5000 Köln 1,3,4,5-tetrahydrobenz(c,d)indole, ein verfahren zu ihrer herstellung und ihre verwendung
US4983622A (en) * 1984-02-06 1991-01-08 Eli Lilly And Company 6-substituted-4-dialkylaminotetrahydrobenz(c,d)indoles
IL74222A (en) * 1984-02-06 1988-07-31 Lilly Co Eli 6-substituted-4-dialkylamino tetrahydrobenz(c,d)indoles,their preparation and pharmaceutical compositions comprising them
US4576959A (en) * 1984-02-06 1986-03-18 Eli Lilly And Company 6-Substituted-4-dialkylaminotetrahydrobenz[c,d]indoles
CA1266482A1 (en) * 1984-05-24 1990-03-06 Carl Kaiser 6-oxygenated-1,3,4,5-tetrahydrobenz(cd)indol-4-amines
DE3525564A1 (de) * 1985-07-15 1987-02-05 Schering Ag Tricyclische verbindungen mit indolstruktur, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
US4745126A (en) * 1987-03-12 1988-05-17 Eli Lilly And Company Method of treating anxiety with tetrahydrobenz[c,d]indole-6-carboxamides
DE3718892A1 (de) * 1987-06-05 1988-12-22 Bayer Ag Polyhydrobenz(c,d)indol-sulfonamide
IL97308A (en) * 1990-02-26 1996-10-31 Lilly Co Eli Xahydrobenz [DC] Induced indoles in position 6, their preparation process and pharmaceutical preparations containing them
US5039820A (en) * 1990-02-26 1991-08-13 Eli Lilly And Company 4-amino-6-iodo-hexahydrobenz(cd)indoles
US5096908A (en) * 1990-05-04 1992-03-17 Eli Lilly And Company Method of inhibiting gastric acid secretion
US5229409A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-tetrahydrobenz[cd]indoles
IL99500A0 (en) * 1990-09-17 1992-08-18 Agouron Pharma Naphthalene compounds,processes for the preparation thereof and pharmaceutical compositions containing the same

Also Published As

Publication number Publication date
IE912879A1 (en) 1992-02-26
NO913158D0 (no) 1991-08-13
EP0471569A1 (en) 1992-02-19
NZ239334A (en) 1993-05-26
YU140391A (sh) 1994-06-10
BR9103479A (pt) 1992-05-12
CS249591A3 (en) 1992-03-18
FI913834A0 (fi) 1991-08-13
IL99149A0 (en) 1992-07-15
HU912707D0 (en) 1992-01-28
CN1058962A (zh) 1992-02-26
NO176019C (no) 1995-01-18
AU8240791A (en) 1992-02-20
PT98639A (pt) 1992-06-30
KR920004346A (ko) 1992-03-27
JPH04230664A (ja) 1992-08-19
FI913834A (fi) 1992-02-16
US5229410A (en) 1993-07-20
AU648331B2 (en) 1994-04-21
HUT59095A (en) 1992-04-28
MX9100644A (es) 1992-04-01
NO176019B (no) 1994-10-10

Similar Documents

Publication Publication Date Title
NO882390L (no) (ih-azol-1-ylmetyl)substituerte benzotriazolderivater og deres fremstilling.
DK297089D0 (da) Pyrimidinderivater og fremgangsmaade til fremstilling deraf
DK48785D0 (da) 6-substituerede 4-dialkylaminotetrahydrobenz(c,d)indoler og fremgangsmaade til fremstilling heraf
NO904921D0 (no) Fremgangsmaate til fremstilling av modifiserte gangliosider og deres funksjonelle derivater.
NO891866L (no) Kromanderivater og fremgangsmaate for fremstilling derav.
NO892745D0 (no) Aminoalkylaminokarbonylaminodiolaminosyrederivater og fremgangsmaate for deres fremstilling.
NO904551D0 (no) Quinolonforbindelser og fremgangsmaate for deres fremstilling.
NO910003D0 (no) Vitamin e derivater og fremgangsmaate for deres fremstilling.
NO870512D0 (no) 1,4-benzoksazinderivater og fremgangsmaate for deres fremstilling.
NO900312L (no) Galliumholdige suspensjoner og fremgangsmaate for deres fremstilling.
NO893196D0 (no) Hybrid-protein-c-sammensetninger og fremgangsmaater for deres fremstilling.
DK581688A (da) L-tyrosinderivater og fremgangsmaade til fremstilling af samme
NO913158L (no) 6-substituert-heksahydrobenz(cd)indoler og fremgangsmaate for deres fremstilling.
NO892494D0 (no) Kromanderivater og fremgangsmaate for fremstilling derav.
NO890894L (no) 4-substituerte pyrazolo(3,4-alfa)pyrimidinderivater og fremgangsmaate for deres fremstilling.
NO894103D0 (no) Kromanderivater og fremgangsmaate for fremstilling derav.
NO880511D0 (no) Substituerte aminderivater og fremgangsmaater for deres fremstilling.
NO904552L (no) Quinolonforbindelser og fremgangsmaate for deres fremstilling.
NO883114D0 (no) 1h-pyrazol-1-alkanamider og fremgangsmaate for deres fremstilling.
NO911047D0 (no) Labdaner og fremgangsmaate for deres fremstilling.
NO904805D0 (no) Fremgangsmaate for fremstilling av antihypertensive og antiarytmiske pyridinderivater.
NO903484D0 (no) Substituerte pyrazinderivater og fremgangsmaate for deres fremstilling.
NO900252D0 (no) Cefasporinderivater og fremgangsmaate for fremstilling derav.
NO893565L (no) Etansulfonamidderivater og fremgangsmaate for deres fremstilling.
NO894697L (no) Penemderivater og fremgangsmaater for deres fremstilling.