NO904300L - Kinolinderivater samt fremstilling og anvendelse derav. - Google Patents

Kinolinderivater samt fremstilling og anvendelse derav.

Info

Publication number
NO904300L
NO904300L NO90904300A NO904300A NO904300L NO 904300 L NO904300 L NO 904300L NO 90904300 A NO90904300 A NO 90904300A NO 904300 A NO904300 A NO 904300A NO 904300 L NO904300 L NO 904300L
Authority
NO
Norway
Prior art keywords
chem
preparation
quinoline derivatives
alkyl group
lower alkyl
Prior art date
Application number
NO90904300A
Other languages
English (en)
Norwegian (no)
Other versions
NO904300D0 (no
Inventor
Kanji Meguro
Hitoshi Ikeda
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO904300D0 publication Critical patent/NO904300D0/no
Publication of NO904300L publication Critical patent/NO904300L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Measurement Of Radiation (AREA)
  • Holo Graphy (AREA)
  • Detergent Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO90904300A 1989-10-06 1990-10-03 Kinolinderivater samt fremstilling og anvendelse derav. NO904300L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP26278289 1989-10-06
JP32229089 1989-12-11

Publications (2)

Publication Number Publication Date
NO904300D0 NO904300D0 (no) 1990-10-03
NO904300L true NO904300L (no) 1991-04-08

Family

ID=26545706

Family Applications (1)

Application Number Title Priority Date Filing Date
NO90904300A NO904300L (no) 1989-10-06 1990-10-03 Kinolinderivater samt fremstilling og anvendelse derav.

Country Status (17)

Country Link
US (1) US5223513A (da)
EP (1) EP0421456B1 (da)
KR (1) KR910007883A (da)
CN (1) CN1050715A (da)
AT (1) ATE116301T1 (da)
AU (1) AU629048B2 (da)
CA (1) CA2026890C (da)
DE (1) DE69015541T2 (da)
FI (1) FI904915A0 (da)
HU (1) HUT55364A (da)
IE (1) IE903454A1 (da)
IL (1) IL95839A (da)
NO (1) NO904300L (da)
NZ (1) NZ235582A (da)
PT (1) PT95515A (da)
RU (1) RU2001910C1 (da)
TW (1) TW205037B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03181465A (ja) * 1989-12-11 1991-08-07 Takeda Chem Ind Ltd キノリン誘導体
EP0590094A1 (en) * 1991-04-26 1994-04-06 Pfizer Inc. 4-aryl-3-(heteroarylureido)quinoline derivatives
ES2125325T3 (es) * 1992-01-23 1999-03-01 Pfizer Derivados de 4-fenil-3-(heteroarilureido)-1,2-dihidro-2-oxoquinolina como agentes antihipercolesterolemicos y antiateroscleroticos.
TW241258B (da) * 1992-04-15 1995-02-21 Takeda Pharm Industry Co Ltd
KR950701621A (ko) * 1992-05-28 1995-04-28 알렌 제이. 스피겔 아실 조효소a : 콜레스테롤 아실 전이효소(acat)의 억제제로서 신규한 n- 아릴 및 n- 헤테로아릴우레아 유도체(new n-aryl and n-heteroarylurea derivatives as inhibitors of acyl coenzyme a : cholesterol acyl transferase(acat)
ATE161530T1 (de) * 1992-09-04 1998-01-15 Takeda Chemical Industries Ltd Kondensierte heterozyklische verbindungen, deren herstellung und verwendung
US5565472A (en) * 1992-12-21 1996-10-15 Pfizer Inc. 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents
NZ264063A (en) * 1993-08-13 1995-11-27 Nihon Nohyaku Co Ltd N-(2-phenylpyrid-3-yl)- and n-(4-phenylpyrimidin-5-yl)-n'-phenylurea derivatives and pharmaceutical compositions
TW263498B (da) * 1993-11-10 1995-11-21 Takeda Pharm Industry Co Ltd
US6133326A (en) 1994-08-31 2000-10-17 Pfizer Inc Compositions and methods for decreasing sebum production
US5843957A (en) * 1995-05-19 1998-12-01 Sumitomo Pharmaceuticals Company, Ltd. Naphthyridine derivatives
EP1011677A4 (en) * 1997-08-28 2002-03-20 Bristol Myers Squibb Co 4-ARYL-3-AMINOQUINOLEIN-2-ONE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS
US6452008B2 (en) 1998-02-25 2002-09-17 Sumitomo Pharmaceuticals Company, Limited Pyridone derivatives and process for preparing the same
AU2547399A (en) 1998-02-25 1999-09-15 Sumitomo Pharmaceuticals Company, Limited Pyridone derivatives and process for producing the same
ES2239145T3 (es) * 2000-02-02 2005-09-16 Warner-Lambert Company Llc Inhibidor doble de la sintesis de ester de colesterilo y de ester de cera avasimibe para el tratamiento de trastornos de la glandula sebacea.
CN1234691C (zh) * 2001-03-02 2006-01-04 住友化学工业株式会社 喹啉-3-羧酸化合物的制备方法
JP4794445B2 (ja) * 2003-09-23 2011-10-19 メルク・シャープ・エンド・ドーム・コーポレイション キノリンカリウムチャネル阻害剤
JP6170060B2 (ja) 2011-11-04 2017-07-26 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 新規アリール−キノリン誘導体

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1216878B (de) * 1963-04-02 1966-05-18 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung von coronargefaesserweiternden Derivaten des 7-Hydroxy-2-oxo-1, 2-dihydrochinolins
NO133758C (da) * 1970-04-04 1976-06-23 Takeda Chemical Industries Ltd
JPS555502B1 (da) * 1971-07-31 1980-02-07
US4530931A (en) * 1983-01-03 1985-07-23 Usv Pharmaceutical Corp. 8-Quinoline carbanilates for the inhibition of lipolysis
DE3586445T2 (de) * 1984-06-26 1993-01-14 Merck & Co Inc Kondensierte benzo-laktam-verbindungen und deren pharmazeutische zusammensetzungen.
IE892088L (en) * 1988-07-12 1990-01-12 William Henry Deryk Morris Quinoline derivatives, their production and use

Also Published As

Publication number Publication date
JPH03223254A (ja) 1991-10-02
HU906360D0 (en) 1991-04-29
IL95839A (en) 1995-03-15
NZ235582A (en) 1992-03-26
IE903454A1 (en) 1991-04-10
AU629048B2 (en) 1992-09-24
HUT55364A (en) 1991-05-28
DE69015541D1 (de) 1995-02-09
PT95515A (pt) 1991-08-14
CA2026890C (en) 2001-09-18
EP0421456A2 (en) 1991-04-10
EP0421456A3 (en) 1991-05-29
AU6370790A (en) 1991-04-11
FI904915A0 (fi) 1990-10-05
CN1050715A (zh) 1991-04-17
KR910007883A (ko) 1991-05-30
EP0421456B1 (en) 1994-12-28
ATE116301T1 (de) 1995-01-15
US5223513A (en) 1993-06-29
TW205037B (da) 1993-05-01
CA2026890A1 (en) 1991-04-07
NO904300D0 (no) 1990-10-03
RU2001910C1 (ru) 1993-10-30
DE69015541T2 (de) 1995-06-01
IL95839A0 (en) 1991-06-30

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