NO890157L - Fremgangsmaate for fremstilling av 1-hydroksialkyl-5-nitroimidazoler. - Google Patents
Fremgangsmaate for fremstilling av 1-hydroksialkyl-5-nitroimidazoler.Info
- Publication number
- NO890157L NO890157L NO89890157A NO890157A NO890157L NO 890157 L NO890157 L NO 890157L NO 89890157 A NO89890157 A NO 89890157A NO 890157 A NO890157 A NO 890157A NO 890157 L NO890157 L NO 890157L
- Authority
- NO
- Norway
- Prior art keywords
- nitroimidazoles
- preparing
- formula
- hydroxial
- cool
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Catalysts (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Preventing Corrosion Or Incrustation Of Metals (AREA)
- Pigments, Carbon Blacks, Or Wood Stains (AREA)
- Luminescent Compositions (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Phenolic Resins Or Amino Resins (AREA)
- Epoxy Resins (AREA)
- Polyurethanes Or Polyureas (AREA)
- Detergent Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8800415A FR2625998B1 (fr) | 1988-01-15 | 1988-01-15 | Procede de preparation d'hydroxyalkyl-1 methyl-2 nitro-5 imidazoles |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO890157D0 NO890157D0 (no) | 1989-01-13 |
| NO890157L true NO890157L (no) | 1989-07-17 |
| NO172798B NO172798B (no) | 1993-06-01 |
| NO172798C NO172798C (no) | 1993-09-08 |
Family
ID=9362336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO890157A NO172798C (no) | 1988-01-15 | 1989-01-13 | Fremgangsmaate for fremstilling av 1-hydroksyalkyl-5-nitroimidazoler |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4925952A (no) |
| EP (1) | EP0324691B1 (no) |
| JP (1) | JPH01216976A (no) |
| KR (1) | KR890011855A (no) |
| CN (1) | CN1023318C (no) |
| AT (1) | ATE70831T1 (no) |
| AU (1) | AU608933B2 (no) |
| CA (1) | CA1310326C (no) |
| DE (1) | DE68900582D1 (no) |
| DK (1) | DK14889A (no) |
| ES (1) | ES2028444T3 (no) |
| FI (1) | FI890186A (no) |
| FR (1) | FR2625998B1 (no) |
| GR (1) | GR3003445T3 (no) |
| HU (1) | HU200447B (no) |
| IL (1) | IL88944A0 (no) |
| MX (1) | MX169604B (no) |
| NO (1) | NO172798C (no) |
| PT (1) | PT89443B (no) |
| SU (1) | SU1657060A3 (no) |
| YU (1) | YU46997B (no) |
| ZA (1) | ZA89307B (no) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE68904436T2 (de) * | 1988-01-15 | 1993-07-29 | Rhone Poulenc Sante | Verfahren zur herstellung von 1-alkyl-5-nitro-imidazolen. |
| FR2625999B1 (fr) * | 1988-01-15 | 1990-06-08 | Rhone Poulenc Sante | Procede de preparation d'hydroxyalkyl-1 methyl-2 nitro-5 imidazoles |
| FR2659326A1 (fr) * | 1990-03-12 | 1991-09-13 | Rhone Poulenc Sante | Procede de preparation d'hydroxyalkyl-1 nitro-5 imidazoles. |
| CN1326840C (zh) * | 2002-10-15 | 2007-07-18 | 大塚制药株式会社 | 1－取代的－4－硝基咪唑化合物及其制备方法 |
| CN102321028B (zh) * | 2011-06-30 | 2013-12-25 | 湖北省宏源药业有限公司 | 一种合成2-甲基-5-硝基咪唑-1-乙醇的方法 |
| RU2531616C1 (ru) * | 2013-03-29 | 2014-10-27 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Национальный исследовательский Томский государственный университет" (ТГУ) | Способ получения метронидазола |
| WO2015198107A1 (en) * | 2014-06-24 | 2015-12-30 | Kiany Fard Taghi | Synthesis of metronidazole |
| US10335390B2 (en) | 2014-09-05 | 2019-07-02 | Symbiomix Therapeutics, Llc | Secnidazole for use in the treatment of bacterial vaginosis |
| US11253501B2 (en) | 2015-06-01 | 2022-02-22 | Lupin Inc. | Secnidazole formulations and use in treating bacterial vaginosis |
| CN110749682A (zh) * | 2019-10-24 | 2020-02-04 | 湖北省宏源药业科技股份有限公司 | 一种2-甲基-5-硝基咪唑含量检测方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3178446A (en) * | 1961-07-27 | 1965-04-13 | Luso Farmaco Inst | Oxyethylation of imidazole compounds |
| FR3270M (fr) * | 1963-10-10 | 1965-04-26 | Rhone Poulenc Sa | Nouveaux dérivés de l'imidazole et compositions les contenant. |
| FR1427627A (fr) * | 1963-10-10 | 1966-02-11 | Rhone Poulenc Sa | Nouveaux dérivés de l'imidazole et leur préparation |
| US3743653A (en) * | 1970-12-28 | 1973-07-03 | Merck & Co Inc | Hydroxyethylation with ethylene sulfate |
| DE3400531A1 (de) * | 1984-01-10 | 1985-07-18 | Basf Ag, 6700 Ludwigshafen | Verfahren zur gewinnung von hochreinem 1(2-hydroxiethyl)-2-methyl-5-nitroimidazol |
| DE68904436T2 (de) * | 1988-01-15 | 1993-07-29 | Rhone Poulenc Sante | Verfahren zur herstellung von 1-alkyl-5-nitro-imidazolen. |
| FR2625999B1 (fr) * | 1988-01-15 | 1990-06-08 | Rhone Poulenc Sante | Procede de preparation d'hydroxyalkyl-1 methyl-2 nitro-5 imidazoles |
-
1988
- 1988-01-15 FR FR8800415A patent/FR2625998B1/fr not_active Expired - Lifetime
-
1989
- 1989-01-12 EP EP89400095A patent/EP0324691B1/fr not_active Expired - Lifetime
- 1989-01-12 DE DE8989400095T patent/DE68900582D1/de not_active Expired - Fee Related
- 1989-01-12 ES ES198989400095T patent/ES2028444T3/es not_active Expired - Lifetime
- 1989-01-12 AT AT89400095T patent/ATE70831T1/de not_active IP Right Cessation
- 1989-01-12 IL IL88944A patent/IL88944A0/xx unknown
- 1989-01-13 DK DK014889A patent/DK14889A/da not_active Application Discontinuation
- 1989-01-13 AU AU28452/89A patent/AU608933B2/en not_active Ceased
- 1989-01-13 CA CA000588181A patent/CA1310326C/fr not_active Expired - Lifetime
- 1989-01-13 US US07/296,710 patent/US4925952A/en not_active Expired - Fee Related
- 1989-01-13 NO NO890157A patent/NO172798C/no unknown
- 1989-01-13 JP JP1005078A patent/JPH01216976A/ja active Pending
- 1989-01-13 ZA ZA89307A patent/ZA89307B/xx unknown
- 1989-01-13 FI FI890186A patent/FI890186A/fi not_active Application Discontinuation
- 1989-01-13 SU SU894613302A patent/SU1657060A3/ru active
- 1989-01-13 HU HU89128A patent/HU200447B/hu not_active IP Right Cessation
- 1989-01-13 PT PT89443A patent/PT89443B/pt not_active IP Right Cessation
- 1989-01-13 CN CN89100185A patent/CN1023318C/zh not_active Expired - Fee Related
- 1989-01-13 YU YU7289A patent/YU46997B/sh unknown
- 1989-01-13 MX MX014534A patent/MX169604B/es unknown
- 1989-01-14 KR KR1019890000395A patent/KR890011855A/ko not_active Application Discontinuation
-
1991
- 1991-12-30 GR GR91401113T patent/GR3003445T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX169604B (es) | 1993-07-14 |
| CN1035288A (zh) | 1989-09-06 |
| DE68900582D1 (de) | 1992-02-06 |
| NO890157D0 (no) | 1989-01-13 |
| EP0324691A1 (fr) | 1989-07-19 |
| FR2625998A1 (fr) | 1989-07-21 |
| FI890186A0 (fi) | 1989-01-13 |
| ATE70831T1 (de) | 1992-01-15 |
| FR2625998B1 (fr) | 1990-06-08 |
| GR3003445T3 (en) | 1993-02-17 |
| IL88944A0 (en) | 1989-08-15 |
| AU608933B2 (en) | 1991-04-18 |
| US4925952A (en) | 1990-05-15 |
| JPH01216976A (ja) | 1989-08-30 |
| YU46997B (sh) | 1994-11-15 |
| FI890186A (fi) | 1989-07-16 |
| PT89443A (pt) | 1990-02-08 |
| HU200447B (en) | 1990-06-28 |
| YU7289A (en) | 1990-12-31 |
| SU1657060A3 (ru) | 1991-06-15 |
| DK14889A (da) | 1989-07-16 |
| ZA89307B (en) | 1989-10-25 |
| NO172798B (no) | 1993-06-01 |
| DK14889D0 (da) | 1989-01-13 |
| HUT49586A (en) | 1989-10-30 |
| CN1023318C (zh) | 1993-12-29 |
| CA1310326C (fr) | 1992-11-17 |
| KR890011855A (ko) | 1989-08-22 |
| PT89443B (pt) | 1993-09-30 |
| NO172798C (no) | 1993-09-08 |
| EP0324691B1 (fr) | 1991-12-27 |
| ES2028444T3 (es) | 1992-07-01 |
| AU2845289A (en) | 1989-07-20 |
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