NO885246L - Vedvarende frigjoeringssystem for substituerte dihydropyridin - kalsium - kanalblokkere. - Google Patents

Vedvarende frigjoeringssystem for substituerte dihydropyridin - kalsium - kanalblokkere.

Info

Publication number
NO885246L
NO885246L NO88885246A NO885246A NO885246L NO 885246 L NO885246 L NO 885246L NO 88885246 A NO88885246 A NO 88885246A NO 885246 A NO885246 A NO 885246A NO 885246 L NO885246 L NO 885246L
Authority
NO
Norway
Prior art keywords
calcium
release system
channel blockers
releasing release
substituted dihydropyridine
Prior art date
Application number
NO88885246A
Other languages
English (en)
Norwegian (no)
Other versions
NO885246D0 (no
Inventor
Madurai Gurusamy Ganesan
Narendra Ragjunathji Desai
Gary Arther Maier
Prakash Shriram Kulkarni
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of NO885246D0 publication Critical patent/NO885246D0/no
Publication of NO885246L publication Critical patent/NO885246L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
NO88885246A 1987-11-25 1988-11-24 Vedvarende frigjoeringssystem for substituerte dihydropyridin - kalsium - kanalblokkere. NO885246L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12544087A 1987-11-25 1987-11-25

Publications (2)

Publication Number Publication Date
NO885246D0 NO885246D0 (no) 1988-11-24
NO885246L true NO885246L (no) 1989-05-26

Family

ID=22419737

Family Applications (1)

Application Number Title Priority Date Filing Date
NO88885246A NO885246L (no) 1987-11-25 1988-11-24 Vedvarende frigjoeringssystem for substituerte dihydropyridin - kalsium - kanalblokkere.

Country Status (15)

Country Link
EP (1) EP0317780B1 (fr)
JP (1) JPH02655A (fr)
KR (1) KR890007746A (fr)
AT (1) ATE76292T1 (fr)
AU (1) AU626187B2 (fr)
DE (1) DE3871343D1 (fr)
DK (1) DK656488A (fr)
ES (1) ES2037179T3 (fr)
FI (1) FI885454A (fr)
GR (1) GR3004988T3 (fr)
IL (1) IL88197A0 (fr)
NO (1) NO885246L (fr)
NZ (1) NZ226987A (fr)
PT (1) PT89055A (fr)
ZA (1) ZA888817B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4117784A1 (de) * 1991-05-31 1992-12-03 Basf Ag Herstellung von protein-polyalkylenglykolkonjugaten
US5834496A (en) * 1991-12-02 1998-11-10 Sepracor, Inc. Methods for treating hypertension using optically pure S(-) felodipine
ATE151090T1 (de) * 1993-06-29 1997-04-15 Heylecina Societe Anonyme Herstellung von aktivierten carbamaten von polyalkylenglycol und ihre verwendung
IE80467B1 (en) * 1995-07-03 1998-07-29 Elan Corp Plc Controlled release formulations for poorly soluble drugs
CA2277220A1 (fr) * 1997-01-10 1998-07-16 Abbott Laboratories Comprime pour liberation regulee d'agents actifs
US6013280A (en) * 1997-10-07 2000-01-11 Fuisz Technologies Ltd. Immediate release dosage forms containing microspheres
SE9704401D0 (sv) * 1997-11-28 1997-11-28 Astra Ab Matrix pellets for greasy, oily or sticky drug substances
US7763769B2 (en) 2001-02-16 2010-07-27 Kci Licensing, Inc. Biocompatible wound dressing
US7700819B2 (en) 2001-02-16 2010-04-20 Kci Licensing, Inc. Biocompatible wound dressing
EP1429126B1 (fr) 2002-12-09 2013-02-13 ISHIDA CO., Ltd. Dispositif de pesage combinatoire
DK1628663T3 (da) 2003-05-15 2010-03-08 Roskamp Res Llc Fremgangsmåde til fremstilling af medikamenter til reduktion af amyloid-aflejring, amyloid-neurotoksicitet og mikrogliose
US7786119B2 (en) 2004-04-01 2010-08-31 Cardiome Pharma Corp. Drug conjugates of ion channel modulating compounds
US7705036B2 (en) 2004-04-01 2010-04-27 Cardiome Pharma Corp. Deuterated aminocyclohexyl ether compounds and processes for preparing same
MX2007005988A (es) 2004-11-18 2007-07-10 Cardiome Pharma Corp Procedimiento sintetico para compuestos de eter aminociclohexilico.
EP1915340B1 (fr) 2005-06-15 2013-08-07 Cardiome Pharma Corp. Procedes synthetiques de preparation de composes d'ether aminocyclohexyle
TWI500422B (zh) 2007-10-05 2015-09-21 Alzheimer S Inst Of America Inc 以(-)-尼代地平(nilvadipine)對映異構物減低類澱粉沉積、類澱粉神經毒性及微神經膠細胞增生之方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA959759A (en) * 1970-01-15 1974-12-24 John J. Miskel Method for absorption of drugs
FR2518403B1 (fr) * 1981-12-22 1987-01-02 Dietlin Francois Procede de preparation de formes pharmaceutiques presentant une resorption par voie digestive amelioree, et les formes pharmaceutiques ainsi obtenues
IT1174779B (it) * 1982-09-27 1987-07-01 Sandoz Ag L'impiego in terapeutica dei derivati della 1,4-di idropiridina
NZ206600A (en) * 1983-05-11 1987-01-23 Alza Corp Osmotic drug delivery device

Also Published As

Publication number Publication date
DE3871343D1 (de) 1992-06-25
KR890007746A (ko) 1989-07-05
NZ226987A (en) 1992-04-28
AU2587088A (en) 1989-05-25
ZA888817B (en) 1989-08-30
FI885454A0 (fi) 1988-11-24
EP0317780B1 (fr) 1992-05-20
DK656488A (da) 1989-05-26
PT89055A (pt) 1989-11-30
AU626187B2 (en) 1992-07-23
EP0317780A1 (fr) 1989-05-31
DK656488D0 (da) 1988-11-24
GR3004988T3 (fr) 1993-04-28
ATE76292T1 (de) 1992-06-15
FI885454A (fi) 1989-05-26
ES2037179T3 (es) 1993-06-16
NO885246D0 (no) 1988-11-24
JPH02655A (ja) 1990-01-05
IL88197A0 (en) 1989-06-30

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