PT89055A - Processo para a preparacao de um sistema de administracao de libertacao sustida para bloqueadores de canal de calcio a base de di-hidropiridinas substituidas - Google Patents
Processo para a preparacao de um sistema de administracao de libertacao sustida para bloqueadores de canal de calcio a base de di-hidropiridinas substituidasInfo
- Publication number
- PT89055A PT89055A PT89055A PT8905588A PT89055A PT 89055 A PT89055 A PT 89055A PT 89055 A PT89055 A PT 89055A PT 8905588 A PT8905588 A PT 8905588A PT 89055 A PT89055 A PT 89055A
- Authority
- PT
- Portugal
- Prior art keywords
- libertacao
- hydropyridines
- replaced
- preparation
- calcium channel
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Heat Sensitive Colour Forming Recording (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12544087A | 1987-11-25 | 1987-11-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT89055A true PT89055A (pt) | 1989-11-30 |
Family
ID=22419737
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT89055A PT89055A (pt) | 1987-11-25 | 1988-11-23 | Processo para a preparacao de um sistema de administracao de libertacao sustida para bloqueadores de canal de calcio a base de di-hidropiridinas substituidas |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0317780B1 (pt) |
JP (1) | JPH02655A (pt) |
KR (1) | KR890007746A (pt) |
AT (1) | ATE76292T1 (pt) |
AU (1) | AU626187B2 (pt) |
DE (1) | DE3871343D1 (pt) |
DK (1) | DK656488A (pt) |
ES (1) | ES2037179T3 (pt) |
FI (1) | FI885454A (pt) |
GR (1) | GR3004988T3 (pt) |
IL (1) | IL88197A0 (pt) |
NO (1) | NO885246L (pt) |
NZ (1) | NZ226987A (pt) |
PT (1) | PT89055A (pt) |
ZA (1) | ZA888817B (pt) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4117784A1 (de) * | 1991-05-31 | 1992-12-03 | Basf Ag | Herstellung von protein-polyalkylenglykolkonjugaten |
US5834496A (en) * | 1991-12-02 | 1998-11-10 | Sepracor, Inc. | Methods for treating hypertension using optically pure S(-) felodipine |
ATE151090T1 (de) * | 1993-06-29 | 1997-04-15 | Heylecina Societe Anonyme | Herstellung von aktivierten carbamaten von polyalkylenglycol und ihre verwendung |
IE80467B1 (en) * | 1995-07-03 | 1998-07-29 | Elan Corp Plc | Controlled release formulations for poorly soluble drugs |
JP5170723B2 (ja) * | 1997-01-10 | 2013-03-27 | アボット・ラボラトリーズ | 活性薬剤の制御放出用錠剤 |
US6013280A (en) * | 1997-10-07 | 2000-01-11 | Fuisz Technologies Ltd. | Immediate release dosage forms containing microspheres |
SE9704401D0 (sv) * | 1997-11-28 | 1997-11-28 | Astra Ab | Matrix pellets for greasy, oily or sticky drug substances |
US7763769B2 (en) | 2001-02-16 | 2010-07-27 | Kci Licensing, Inc. | Biocompatible wound dressing |
US7700819B2 (en) | 2001-02-16 | 2010-04-20 | Kci Licensing, Inc. | Biocompatible wound dressing |
EP1429126B1 (en) | 2002-12-09 | 2013-02-13 | ISHIDA CO., Ltd. | Combination weighing device |
CA2525970C (en) | 2003-05-15 | 2011-03-22 | Roskamp Research, Llc | Use of nilvadipine for reducing amyloid deposition, amyloid neurotoxicity and microgliosis |
WO2005094897A2 (en) * | 2004-04-01 | 2005-10-13 | Cardiome Pharma Corp. | Pegylated ion channel modulating compounds |
US7705036B2 (en) | 2004-04-01 | 2010-04-27 | Cardiome Pharma Corp. | Deuterated aminocyclohexyl ether compounds and processes for preparing same |
WO2006088525A1 (en) | 2004-11-18 | 2006-08-24 | Cardiome Pharma Corp. | Synthetic process for aminocyclohexyl ether compounds |
CA2612375C (en) | 2005-06-15 | 2013-08-06 | Cardiome Pharma Corp. | Synthetic processes for the preparation of aminocyclohexyl ether compounds |
JP5411145B2 (ja) | 2007-10-05 | 2014-02-12 | アルツハイマーズ・インスティテュート・オブ・アメリカ・インコーポレイテッド | (−)−ニルバジピンエナンチオマーによってアミロイド沈着、アミロイド神経毒性、およびミクログリオーシスを減少させる方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA959759A (en) * | 1970-01-15 | 1974-12-24 | John J. Miskel | Method for absorption of drugs |
FR2518403B1 (fr) * | 1981-12-22 | 1987-01-02 | Dietlin Francois | Procede de preparation de formes pharmaceutiques presentant une resorption par voie digestive amelioree, et les formes pharmaceutiques ainsi obtenues |
AU1956083A (en) * | 1982-09-27 | 1984-04-05 | Sandoz Ltd. | Compositions containing benzoxadiazole - or benzthiadiazole - dihydropyridines |
NZ206600A (en) * | 1983-05-11 | 1987-01-23 | Alza Corp | Osmotic drug delivery device |
-
1988
- 1988-10-26 DE DE8888117844T patent/DE3871343D1/de not_active Expired - Lifetime
- 1988-10-26 AT AT88117844T patent/ATE76292T1/de active
- 1988-10-26 ES ES198888117844T patent/ES2037179T3/es not_active Expired - Lifetime
- 1988-10-26 EP EP88117844A patent/EP0317780B1/en not_active Expired - Lifetime
- 1988-10-28 IL IL88197A patent/IL88197A0/xx unknown
- 1988-11-17 NZ NZ226987A patent/NZ226987A/en unknown
- 1988-11-23 PT PT89055A patent/PT89055A/pt not_active Application Discontinuation
- 1988-11-23 AU AU25870/88A patent/AU626187B2/en not_active Expired - Fee Related
- 1988-11-24 NO NO88885246A patent/NO885246L/no unknown
- 1988-11-24 FI FI885454A patent/FI885454A/fi not_active Application Discontinuation
- 1988-11-24 JP JP63294806A patent/JPH02655A/ja active Pending
- 1988-11-24 ZA ZA888817A patent/ZA888817B/xx unknown
- 1988-11-24 DK DK656488A patent/DK656488A/da not_active Application Discontinuation
- 1988-11-25 KR KR1019880015572A patent/KR890007746A/ko not_active Application Discontinuation
-
1992
- 1992-06-19 GR GR920400263T patent/GR3004988T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0317780A1 (en) | 1989-05-31 |
NZ226987A (en) | 1992-04-28 |
KR890007746A (ko) | 1989-07-05 |
IL88197A0 (en) | 1989-06-30 |
JPH02655A (ja) | 1990-01-05 |
ZA888817B (en) | 1989-08-30 |
GR3004988T3 (pt) | 1993-04-28 |
NO885246D0 (no) | 1988-11-24 |
DK656488A (da) | 1989-05-26 |
EP0317780B1 (en) | 1992-05-20 |
ES2037179T3 (es) | 1993-06-16 |
NO885246L (no) | 1989-05-26 |
AU2587088A (en) | 1989-05-25 |
FI885454A0 (fi) | 1988-11-24 |
DE3871343D1 (de) | 1992-06-25 |
FI885454A (fi) | 1989-05-26 |
DK656488D0 (da) | 1988-11-24 |
ATE76292T1 (de) | 1992-06-15 |
AU626187B2 (en) | 1992-07-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC3A | Refusal |
Effective date: 19930201 |