NO883188L - Fremgangsmaate til fremstilling av stabile okspenem-3-karboksylsyrer. - Google Patents

Fremgangsmaate til fremstilling av stabile okspenem-3-karboksylsyrer.

Info

Publication number
NO883188L
NO883188L NO88883188A NO883188A NO883188L NO 883188 L NO883188 L NO 883188L NO 88883188 A NO88883188 A NO 88883188A NO 883188 A NO883188 A NO 883188A NO 883188 L NO883188 L NO 883188L
Authority
NO
Norway
Prior art keywords
carbon
pharmaceutically acceptable
bonded
single bonds
okspenem
Prior art date
Application number
NO88883188A
Other languages
English (en)
Other versions
NO883188D0 (no
Inventor
Hans Rolf Pfaendler
Wolfram Hendel
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NO883188D0 publication Critical patent/NO883188D0/no
Publication of NO883188L publication Critical patent/NO883188L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D503/00Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO88883188A 1987-07-31 1988-07-18 Fremgangsmaate til fremstilling av stabile okspenem-3-karboksylsyrer. NO883188L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873725375 DE3725375A1 (de) 1987-07-31 1987-07-31 Stabile oxapenem-3-carbonsaeuren

Publications (2)

Publication Number Publication Date
NO883188D0 NO883188D0 (no) 1988-07-18
NO883188L true NO883188L (no) 1989-02-01

Family

ID=6332772

Family Applications (1)

Application Number Title Priority Date Filing Date
NO88883188A NO883188L (no) 1987-07-31 1988-07-18 Fremgangsmaate til fremstilling av stabile okspenem-3-karboksylsyrer.

Country Status (20)

Country Link
US (1) US5096899A (no)
EP (1) EP0301394B1 (no)
JP (1) JPH0819135B2 (no)
KR (1) KR890002169A (no)
CN (1) CN1031533A (no)
AT (1) ATE95521T1 (no)
AU (1) AU618013B2 (no)
CA (1) CA1339450C (no)
DD (1) DD282012A5 (no)
DE (2) DE3725375A1 (no)
DK (1) DK425888A (no)
ES (1) ES2060628T3 (no)
FI (1) FI883553A (no)
HU (1) HU203355B (no)
IE (1) IE63026B1 (no)
IL (1) IL87254A (no)
NO (1) NO883188L (no)
PH (1) PH27226A (no)
PT (1) PT88118B (no)
ZA (1) ZA885571B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3833693A1 (de) * 1988-10-04 1990-04-05 Bayer Ag Stabile oxapenem-3-carbonsaeuren und ihre verwendung als ss-lactamasehemmer
DE4027928A1 (de) * 1990-09-04 1992-03-05 Bayer Ag Neue 2-tert.substituierte methyl-oxapenem-3-carbonsaeuren und -ester, verfahren zu ihrer herstellung und ihre verwendung
DE4142423A1 (de) * 1991-12-20 1993-06-24 Pfaendler Hans Rudolf ((ls)-hydroxyalkyl)oxapenem-3-carbonsaeuren und ihre verwendung als betalactamasehemmer
CN1219512C (zh) * 2000-10-19 2005-09-21 阿姆拉有限公司 含奥沙培南-3-羧酸的药物组合物
EP1199077A1 (en) * 2000-10-19 2002-04-24 Amura Limited Stable compositions of oxapenem-3-carboxylic acids by Co-lyophilisation with pharmaceutical carriers
GB2369358A (en) * 2000-10-19 2002-05-29 Amura Ltd Oxapenems and pharmaceutical compositions thereof
GB0106428D0 (en) * 2001-03-15 2001-05-02 Amura Ltd Antibacterial composition
AR039774A1 (es) * 2002-05-01 2005-03-02 Wyeth Corp 6-alquiliden-penems biciclicos como inhibidores de beta-lactamasas
AR039475A1 (es) * 2002-05-01 2005-02-23 Wyeth Corp 6-alquiliden-penems triciclicos como inhibidores de beta-lactamasa
EP2167081B1 (en) 2007-05-21 2013-06-26 Hans Rudolf Pfaendler Bactericidal anti-mrsa active pharmaceutical composition containing carbapenems
WO2009089380A2 (en) * 2008-01-08 2009-07-16 The Trustees Of Columbia University In The City Of New York Methods for p2ry5 mediated regulation of hair growth and mutants thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1368236A (en) * 1970-11-03 1974-09-25 Glaxo Lab Ltd Azetidinone derivatives and their preparation
AU498131B2 (en) * 1974-02-26 1979-02-15 Ciba-Geigy Ag Production of cephems by cyclization
IE41109B1 (en) * 1974-04-20 1979-10-24 Beecham Group Ltd Novel -lactam antibiotic from streptomyces clavuligerus
CA1136132A (en) * 1975-02-17 1982-11-23 Teruji Tsuji Cyclization to form cephem ring and intermediates therefor
US4147864A (en) * 1975-02-20 1979-04-03 Ciba-Geigy Corporation Process for the manufacture of 7β-amino-3-cephem-3-ol-4 carboxylic acid compounds
US4024152A (en) * 1975-09-19 1977-05-17 Eli Lilly And Company 4-Dithio-3-imido-azetidin-2-ones
GB1529913A (en) * 1976-02-04 1978-10-25 Beecham Group Ltd Beta-lactam compounds
GB1591438A (en) * 1976-09-09 1981-06-24 Glaxo Lab Ltd Clavem derivatives
JPS5359657A (en) * 1976-09-09 1978-05-29 Glaxo Lab Ltd Novel compound and preparation thereof
GB1593275A (en) * 1976-10-22 1981-07-15 Glaxo Lab Ltd Clavam derivatives
DK139377A (da) * 1977-03-10 1978-09-11 Beecham Group Ltd Fremgangsmaade til fremstilling af ethere
US4260627A (en) * 1978-10-24 1981-04-07 Merck & Co., Inc. 1-, 6- And 2-substituted-1-carba-2-penem-3-carboxylic acids
GB2045236A (en) * 1979-03-26 1980-10-29 Hoechst Uk Ltd Oxapenem derivatives

Also Published As

Publication number Publication date
IE63026B1 (en) 1995-03-22
DD282012A5 (de) 1990-08-29
JPS6442484A (en) 1989-02-14
IE882347L (en) 1989-01-31
CN1031533A (zh) 1989-03-08
CA1339450C (en) 1997-09-09
EP0301394B1 (de) 1993-10-06
KR890002169A (ko) 1989-04-08
PH27226A (en) 1993-05-04
FI883553A0 (fi) 1988-07-28
HU203355B (en) 1991-07-29
ZA885571B (en) 1989-04-26
IL87254A0 (en) 1988-12-30
DE3884705D1 (de) 1993-11-11
HUT48889A (en) 1989-07-28
DE3725375A1 (de) 1989-02-09
PT88118B (pt) 1995-03-01
JPH0819135B2 (ja) 1996-02-28
ATE95521T1 (de) 1993-10-15
ES2060628T3 (es) 1994-12-01
AU2004088A (en) 1989-02-02
DK425888D0 (da) 1988-07-29
EP0301394A1 (de) 1989-02-01
PT88118A (pt) 1989-06-30
US5096899A (en) 1992-03-17
NO883188D0 (no) 1988-07-18
FI883553A (fi) 1989-02-01
IL87254A (en) 1993-01-31
AU618013B2 (en) 1991-12-12
DK425888A (da) 1989-02-01

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