NO870631L - Cykloheksenkarboksylsyre-estere og -amider. - Google Patents

Cykloheksenkarboksylsyre-estere og -amider.

Info

Publication number
NO870631L
NO870631L NO870631A NO870631A NO870631L NO 870631 L NO870631 L NO 870631L NO 870631 A NO870631 A NO 870631A NO 870631 A NO870631 A NO 870631A NO 870631 L NO870631 L NO 870631L
Authority
NO
Norway
Prior art keywords
hexencarboxylic
amides
cycle
acid esters
represents hydrogen
Prior art date
Application number
NO870631A
Other languages
English (en)
Other versions
NO870631D0 (no
Inventor
Bruce Harrison Toder
Original Assignee
Pennwalt Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pennwalt Corp filed Critical Pennwalt Corp
Publication of NO870631D0 publication Critical patent/NO870631D0/no
Publication of NO870631L publication Critical patent/NO870631L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Terapeutisk aktive forbindelser med formel I. hvori Ri er C-Calkylkarboksylat eller. BS Rer enten uavhengig hydrogen, C-Ccykloalkyl eller CCalkyl, eller Rog Rsammen med det vedsidenavliggende nitrogenatom danner en 5-7 leddet mettet heterosyklisk ring som inneholder 4-6 karbonatomer og 1-2 heteroatomer utvalgt blant N, 0 eller S,. Rog Rer uavhengig hydrogen, C!-Calkyl eller C-Ccykloalkyl, og. n er 2 eller 3, omfattende alle rasemiske, optisk aktive og stereoisomeriske former derav, og omfattende alle farmasøytisk akseptable salter derav.Fremgangsmåten for deres fremstilling er beskrevet.
NO870631A 1986-02-18 1987-02-17 Cykloheksenkarboksylsyre-estere og -amider. NO870631L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/830,592 US4760146A (en) 1986-02-18 1986-02-18 Cyclohexene carboxylic esters and amides as antidysrhythmic agents

Publications (2)

Publication Number Publication Date
NO870631D0 NO870631D0 (no) 1987-02-17
NO870631L true NO870631L (no) 1987-08-19

Family

ID=25257271

Family Applications (1)

Application Number Title Priority Date Filing Date
NO870631A NO870631L (no) 1986-02-18 1987-02-17 Cykloheksenkarboksylsyre-estere og -amider.

Country Status (12)

Country Link
US (1) US4760146A (no)
EP (1) EP0233512A1 (no)
JP (1) JPS62246544A (no)
KR (1) KR870007875A (no)
AU (1) AU6764487A (no)
DE (1) DE233512T1 (no)
DK (1) DK78587A (no)
ES (1) ES2000110A4 (no)
FI (1) FI870662A (no)
IL (1) IL81132A0 (no)
NO (1) NO870631L (no)
ZA (1) ZA871172B (no)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2812331A (en) * 1957-11-05 Substituted butyric acid amide com-
CH471124A (de) * 1965-09-29 1969-04-15 Ciba Geigy Verfahren zur Herstellung von neuen Cyclohexanderivaten
FR5978M (no) * 1965-11-19 1968-04-22
US3951978A (en) * 1972-04-22 1976-04-20 Istituto Luso Farmaco D'italia S.R.L. 1,3-Disubstituted 3-aroylpropanes and process for the preparation thereof
US3974157A (en) * 1974-03-04 1976-08-10 Pennwalt Corporation 1-(Amino-alkyl)-2-aryl-cyclohexane alcohols and esters
US4452745A (en) * 1981-02-06 1984-06-05 Eli Lilly And Company 9-Aminoalkylfluorenes
US4595759A (en) * 1983-08-19 1986-06-17 Pennwalt Corporation Cyclohexane carboxylic acids and derivatives thereof as antidysrhythmic agents

Also Published As

Publication number Publication date
ES2000110A4 (es) 1987-12-16
FI870662A0 (fi) 1987-02-17
FI870662A (fi) 1987-08-19
EP0233512A1 (en) 1987-08-26
JPS62246544A (ja) 1987-10-27
ZA871172B (en) 1987-09-30
DK78587A (da) 1987-08-19
US4760146A (en) 1988-07-26
DE233512T1 (de) 1988-01-14
AU6764487A (en) 1987-08-20
IL81132A0 (en) 1987-03-31
DK78587D0 (da) 1987-02-17
KR870007875A (ko) 1987-09-22
NO870631D0 (no) 1987-02-17

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