NO865068L - System, fremgangsmaate og apparat til fraksjonering av blod in situ. - Google Patents
System, fremgangsmaate og apparat til fraksjonering av blod in situ.Info
- Publication number
- NO865068L NO865068L NO865068A NO865068A NO865068L NO 865068 L NO865068 L NO 865068L NO 865068 A NO865068 A NO 865068A NO 865068 A NO865068 A NO 865068A NO 865068 L NO865068 L NO 865068L
- Authority
- NO
- Norway
- Prior art keywords
- blood
- plasma
- donor
- volume
- anticoagulant
- Prior art date
Links
- 210000004369 blood Anatomy 0.000 title claims description 243
- 239000008280 blood Substances 0.000 title claims description 243
- 238000000034 method Methods 0.000 title claims description 55
- 210000002381 plasma Anatomy 0.000 claims description 202
- 239000003146 anticoagulant agent Substances 0.000 claims description 42
- 229940127219 anticoagulant drug Drugs 0.000 claims description 41
- 239000000126 substance Substances 0.000 claims description 27
- 230000017531 blood circulation Effects 0.000 claims description 26
- 238000012546 transfer Methods 0.000 claims description 26
- 238000005534 hematocrit Methods 0.000 claims description 21
- 238000012545 processing Methods 0.000 claims description 15
- 238000000926 separation method Methods 0.000 claims description 13
- 230000037396 body weight Effects 0.000 claims description 11
- 230000004044 response Effects 0.000 claims description 8
- 230000036470 plasma concentration Effects 0.000 claims description 5
- 239000003085 diluting agent Substances 0.000 claims description 4
- 238000005303 weighing Methods 0.000 claims description 3
- 238000010923 batch production Methods 0.000 claims description 2
- 238000007865 diluting Methods 0.000 claims description 2
- 238000005086 pumping Methods 0.000 claims description 2
- 210000000056 organ Anatomy 0.000 claims 5
- 238000000605 extraction Methods 0.000 claims 1
- 239000012528 membrane Substances 0.000 description 33
- 210000001772 blood platelet Anatomy 0.000 description 29
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 20
- 210000002105 tongue Anatomy 0.000 description 11
- 238000009826 distribution Methods 0.000 description 9
- 238000004519 manufacturing process Methods 0.000 description 8
- 238000010261 blood fractionation Methods 0.000 description 7
- 238000003306 harvesting Methods 0.000 description 7
- 239000011148 porous material Substances 0.000 description 7
- 238000013461 design Methods 0.000 description 6
- 238000010586 diagram Methods 0.000 description 6
- 230000009467 reduction Effects 0.000 description 6
- 230000008901 benefit Effects 0.000 description 5
- 210000003743 erythrocyte Anatomy 0.000 description 5
- 238000005194 fractionation Methods 0.000 description 5
- 230000033228 biological regulation Effects 0.000 description 4
- 238000004422 calculation algorithm Methods 0.000 description 4
- 239000000306 component Substances 0.000 description 4
- 238000010276 construction Methods 0.000 description 4
- 239000012530 fluid Substances 0.000 description 4
- 238000004891 communication Methods 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 239000011159 matrix material Substances 0.000 description 3
- 238000012552 review Methods 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 210000003462 vein Anatomy 0.000 description 3
- 230000010100 anticoagulation Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 238000011065 in-situ storage Methods 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 238000005457 optimization Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 239000012266 salt solution Substances 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 125000006850 spacer group Chemical group 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- 238000003466 welding Methods 0.000 description 2
- 208000035985 Body Odor Diseases 0.000 description 1
- 206010006956 Calcium deficiency Diseases 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 102100026933 Myelin-associated neurite-outgrowth inhibitor Human genes 0.000 description 1
- 206010040904 Skin odour abnormal Diseases 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 244000105017 Vicia sativa Species 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000003114 blood coagulation factor Substances 0.000 description 1
- 239000012503 blood component Substances 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 238000004590 computer program Methods 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 210000002445 nipple Anatomy 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 230000002572 peristaltic effect Effects 0.000 description 1
- 238000002616 plasmapheresis Methods 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000007665 sagging Methods 0.000 description 1
- 238000009958 sewing Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 231100000057 systemic toxicity Toxicity 0.000 description 1
- 231100000816 toxic dose Toxicity 0.000 description 1
- 238000009827 uniform distribution Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3496—Plasmapheresis; Leucopheresis; Lymphopheresis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/147—Microfiltration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/18—Apparatus therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/22—Controlling or regulating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/08—Flat membrane modules
- B01D63/082—Flat membrane modules comprising a stack of flat membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0415—Plasma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/20—Blood composition characteristics
- A61M2230/207—Blood composition characteristics hematocrit
Landscapes
- Engineering & Computer Science (AREA)
- Water Supply & Treatment (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/809,923 US4898675A (en) | 1983-08-15 | 1985-12-15 | System and method for continuously fractionating blood in situ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO865068D0 NO865068D0 (no) | 1986-12-15 |
| NO865068L true NO865068L (no) | 1987-06-16 |
Family
ID=25202506
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO865068A NO865068L (no) | 1985-12-15 | 1986-12-15 | System, fremgangsmaate og apparat til fraksjonering av blod in situ. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4898675A (fr) |
| EP (1) | EP0229504A3 (fr) |
| JP (1) | JPS62189075A (fr) |
| KR (1) | KR870005651A (fr) |
| AU (1) | AU6651886A (fr) |
| BR (1) | BR8606337A (fr) |
| DE (1) | DE229504T1 (fr) |
| DK (1) | DK603786A (fr) |
| ES (1) | ES2000103A4 (fr) |
| FI (1) | FI865105A (fr) |
| IL (1) | IL80967A0 (fr) |
| NO (1) | NO865068L (fr) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63115569A (ja) * | 1986-11-01 | 1988-05-20 | 株式会社 ニツシヨ− | 血漿採取装置 |
| JP2555574B2 (ja) * | 1986-11-26 | 1996-11-20 | ブラザー工業株式会社 | 布縁倣い縫ミシン |
| US5372709A (en) * | 1988-12-13 | 1994-12-13 | Bio-Flo Limited | Fluid flow control apparatus |
| US5817042A (en) * | 1992-03-04 | 1998-10-06 | Cobe Laboratories, Inc. | Method and apparatus for controlling concentrations in vivos and in tubing systems |
| US5496265A (en) * | 1992-03-04 | 1996-03-05 | Cobe Laboratories, Inc. | Blood component collection system with optimizer |
| US5378227A (en) * | 1992-08-11 | 1995-01-03 | Cobe Laboratories, Inc. | Biological/pharmaceutical method and apparatus for collecting and mixing fluids |
| WO2001065463A2 (fr) * | 2000-03-01 | 2001-09-07 | Gambro, Inc. | Systeme extracorporel de gestion d'information en matiere de traitement du sang |
| US7430478B2 (en) | 2000-03-01 | 2008-09-30 | Caridian Bct, Inc. | Blood processing information system with blood loss equivalency tracking |
| US6793643B1 (en) * | 2000-04-21 | 2004-09-21 | Therakos, Inc. | Low extracorporeal volume treatment system |
| CA2382371C (fr) * | 2000-07-07 | 2011-09-20 | Baxter International Inc. | Systeme, procede et appareil medicaux utilisant des dispositifs mem |
| ATE506089T1 (de) * | 2003-07-31 | 2011-05-15 | Debiotech Sa | System zur durchführung von flüssigkeitsverabreichung in der peritonealdialyse |
| US7087177B2 (en) * | 2004-04-16 | 2006-08-08 | Baxter International Inc. | Methods for determining flow rates of biological fluids |
| JP5142639B2 (ja) * | 2007-09-05 | 2013-02-13 | オリンパスメディカルシステムズ株式会社 | 医療業務支援システム、医療業務支援サーバ |
| US8114276B2 (en) | 2007-10-24 | 2012-02-14 | Baxter International Inc. | Personal hemodialysis system |
| US8123713B2 (en) * | 2008-08-12 | 2012-02-28 | Caridian Bct, Inc. | System and method for collecting plasma protein fractions from separated blood components |
| EP2421581B1 (fr) * | 2009-04-23 | 2020-02-19 | Fresenius Medical Care Deutschland GmbH | Dispositif de traitement pour traitement sanguin extracorporel d'un patient |
| US11386993B2 (en) | 2011-05-18 | 2022-07-12 | Fenwal, Inc. | Plasma collection with remote programming |
| US9802161B2 (en) * | 2011-11-10 | 2017-10-31 | Pall Corporation | Fluid treatment assemblies |
| US9733805B2 (en) | 2012-06-26 | 2017-08-15 | Terumo Bct, Inc. | Generating procedures for entering data prior to separating a liquid into components |
| EP2896415B1 (fr) * | 2012-09-11 | 2018-05-30 | Terumo Kabushiki Kaisha | Dispositif de séparation des composants sanguins |
| DE102017113061A1 (de) * | 2017-06-14 | 2018-12-20 | Fresenius Medical Care Deutschland Gmbh | Verfahren und Vorrichtung zur Zugabe eines Antikoagulans in das Blut eines Patienten |
| US11412967B2 (en) | 2018-05-21 | 2022-08-16 | Fenwal, Inc. | Systems and methods for plasma collection |
| EP3954407B1 (fr) * | 2018-05-21 | 2023-07-12 | Fenwal, Inc. | Systèmes et procédés d'optimisation de volumes de collecte de plasma |
| DE102019125355A1 (de) * | 2019-09-20 | 2021-03-25 | B.Braun Avitum Ag | Verfahren und Vorrichtung zur Steuerung der Antikoagulation bei der extrakorporalen Blutbehandlung |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4370983A (en) * | 1971-01-20 | 1983-02-01 | Lichtenstein Eric Stefan | Computer-control medical care system |
| US4729829A (en) * | 1981-07-22 | 1988-03-08 | E. I. Du Pont De Nemours And Company | Hollow fiber plasmapheresis module |
| US4582598A (en) * | 1981-12-15 | 1986-04-15 | Baxter Travenol Laboratories, Inc. | Replacement fluid control system for a blood fractionation apparatus and the like |
| US4469593A (en) * | 1982-03-10 | 1984-09-04 | Kabushiki Kaisha Toyota Chuo Kenkyusho | Blood purification apparatus |
| DE3313421C2 (de) * | 1983-04-13 | 1985-08-08 | Fresenius AG, 6380 Bad Homburg | Einrichtung zum Regeln der Ultrafiltrationsrate bei Vorrichtungen zum extrakorporalen Reinigen von Blut |
| US4980068A (en) * | 1983-08-15 | 1990-12-25 | Lavender Ardis R | System, apparatus and method for continuously fractionating blood in situ |
| US4668400A (en) * | 1984-06-22 | 1987-05-26 | Veech Richard L | Hemodialysis processes and hemodialysis solutions |
| JPH0657250B2 (ja) * | 1984-06-29 | 1994-08-03 | バクスター・インターナショナル・インコーポレーテッド | 血液抽出及び再注輸の血流制御装置 |
| US4708713A (en) * | 1984-11-16 | 1987-11-24 | Anisa Medical, Inc. | Method and system for removing immunosuppressive components from the blood of mammals |
-
1985
- 1985-12-15 US US06/809,923 patent/US4898675A/en not_active Expired - Fee Related
-
1986
- 1986-12-12 JP JP61296479A patent/JPS62189075A/ja active Pending
- 1986-12-15 DE DE198686309774T patent/DE229504T1/de active Pending
- 1986-12-15 IL IL80967A patent/IL80967A0/xx unknown
- 1986-12-15 KR KR860010723A patent/KR870005651A/ko not_active Application Discontinuation
- 1986-12-15 EP EP86309774A patent/EP0229504A3/fr not_active Withdrawn
- 1986-12-15 NO NO865068A patent/NO865068L/no unknown
- 1986-12-15 FI FI865105A patent/FI865105A/fi not_active Application Discontinuation
- 1986-12-15 DK DK603786A patent/DK603786A/da not_active Application Discontinuation
- 1986-12-15 ES ES86309774T patent/ES2000103A4/es active Pending
- 1986-12-15 AU AU66518/86A patent/AU6651886A/en not_active Abandoned
- 1986-12-19 BR BR8606337A patent/BR8606337A/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU6651886A (en) | 1987-06-18 |
| FI865105A0 (fi) | 1986-12-15 |
| FI865105A (fi) | 1987-06-17 |
| US4898675A (en) | 1990-02-06 |
| NO865068D0 (no) | 1986-12-15 |
| EP0229504A2 (fr) | 1987-07-22 |
| BR8606337A (pt) | 1987-10-06 |
| JPS62189075A (ja) | 1987-08-18 |
| KR870005651A (ko) | 1987-07-06 |
| EP0229504A3 (fr) | 1989-07-19 |
| DK603786A (da) | 1987-06-17 |
| DK603786D0 (da) | 1986-12-15 |
| ES2000103A4 (es) | 1987-12-01 |
| IL80967A0 (en) | 1987-03-31 |
| DE229504T1 (de) | 1988-02-04 |
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