NO802720L - BENZOFENONE DERIVATIVES. - Google Patents

BENZOFENONE DERIVATIVES.

Info

Publication number
NO802720L
NO802720L NO802720A NO802720A NO802720L NO 802720 L NO802720 L NO 802720L NO 802720 A NO802720 A NO 802720A NO 802720 A NO802720 A NO 802720A NO 802720 L NO802720 L NO 802720L
Authority
NO
Norway
Prior art keywords
benzofenone
derivatives
benzofenone derivatives
Prior art date
Application number
NO802720A
Other languages
Norwegian (no)
Other versions
NO148188C (en
NO148188B (en
Inventor
Rodney Ian Fryer
Armin Walser
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO802720L publication Critical patent/NO802720L/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO148188B publication Critical patent/NO148188B/en
Publication of NO148188C publication Critical patent/NO148188C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
NO802720A 1974-09-11 1980-09-12 BENZOFENON DERIVATIVES AS INTERMEDIATES IN THE PREPARATION OF IMIDAZO (1,5-ALFA) (1,4) -BENZODIAZEPINES NO148188C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50492474A 1974-09-11 1974-09-11

Publications (3)

Publication Number Publication Date
NO802720L true NO802720L (en) 1976-03-12
NO148188B NO148188B (en) 1983-05-16
NO148188C NO148188C (en) 1983-08-24

Family

ID=24008278

Family Applications (4)

Application Number Title Priority Date Filing Date
NO753069A NO147109C (en) 1974-09-11 1975-09-08 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE DIAZEPINE DERIVATIVES
NO802720A NO148188C (en) 1974-09-11 1980-09-12 BENZOFENON DERIVATIVES AS INTERMEDIATES IN THE PREPARATION OF IMIDAZO (1,5-ALFA) (1,4) -BENZODIAZEPINES
NO802719A NO147914C (en) 1974-09-11 1980-09-12 INTERMEDIATE IN THE PREPARATION OF PHARMACOLOGICAL ACTIVE IMIDAZOLE (1,5-A) (1,4) DIAZEPINE COMPOUNDS
NO802718A NO146573C (en) 1974-09-11 1980-09-12 3A, 4-DIHYDRO-IMIDAZO (1,5-A) (1,4) -DIAZEPINES USED AS INTERMEDIATES FOR THE PREPARATION OF THERAPEUTICALLY EFFECTIVE IMIDAZO (1,5-A) (1,4) DIAZEPINES

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO753069A NO147109C (en) 1974-09-11 1975-09-08 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE DIAZEPINE DERIVATIVES

Family Applications After (2)

Application Number Title Priority Date Filing Date
NO802719A NO147914C (en) 1974-09-11 1980-09-12 INTERMEDIATE IN THE PREPARATION OF PHARMACOLOGICAL ACTIVE IMIDAZOLE (1,5-A) (1,4) DIAZEPINE COMPOUNDS
NO802718A NO146573C (en) 1974-09-11 1980-09-12 3A, 4-DIHYDRO-IMIDAZO (1,5-A) (1,4) -DIAZEPINES USED AS INTERMEDIATES FOR THE PREPARATION OF THERAPEUTICALLY EFFECTIVE IMIDAZO (1,5-A) (1,4) DIAZEPINES

Country Status (32)

Country Link
JP (1) JPS51125099A (en)
AT (1) AT360023B (en)
AU (1) AU505998B2 (en)
BE (1) BE833248A (en)
BR (1) BR7505864A (en)
CA (1) CA1067491A (en)
CH (2) CH619953A5 (en)
CU (1) CU20892L (en)
DD (1) DD121640A5 (en)
DE (1) DE2540522A1 (en)
DK (1) DK157615C (en)
ES (1) ES440850A1 (en)
FI (1) FI63234C (en)
FR (2) FR2285890A1 (en)
GB (1) GB1527131A (en)
HK (1) HK63381A (en)
HU (1) HU174752B (en)
IE (1) IE41844B1 (en)
IL (1) IL48069A (en)
KE (1) KE3173A (en)
LU (1) LU73356A1 (en)
MX (1) MX160600A (en)
MY (1) MY8200214A (en)
NL (1) NL171060C (en)
NO (4) NO147109C (en)
NZ (1) NZ178635A (en)
PH (2) PH16152A (en)
PL (1) PL106563B1 (en)
SE (4) SE425785B (en)
SU (1) SU814278A3 (en)
YU (1) YU40267B (en)
ZA (1) ZA755418B (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4125726A (en) * 1977-03-11 1978-11-14 Hoffmann-La Roche Inc. Imidazo[1,5-a][1,4]benzodiazepines
US4118386A (en) * 1977-04-04 1978-10-03 Hoffmann-La Roche Inc. Synthesis of imidazo[1,5-a]diazepine-3-carboxylates
US4226768A (en) * 1979-05-29 1980-10-07 Hoffmann-La Roche Inc. Process for the preparation of imidazobenzodiazepines
US4226771A (en) * 1979-07-25 1980-10-07 Hoffmann-La Roche Inc. 1,2,5-Oxadiazino[5,4-a][1,4]benzodiazepine derivatives
US4256637A (en) * 1979-12-20 1981-03-17 Hoffmann-La Roche Inc. Intermediates for the production of imidazobenzodiazepines
FR2479818A1 (en) * 1980-04-03 1981-10-09 Roussel Uclaf 2-Substd. phenyl 7-nitro 3H 1,4-benzodiazepinyl aminoacid derivs. - are anxiolytics, tranquillisers, sedatives and anticonvulsants, prepd. by reacting aminoacid or peptide with benzodiazepin-2-thione
US4335042A (en) * 1980-04-21 1982-06-15 Hoffmann-La Roche Inc. Process to produce imidazobenzodiazepine intermediates
DE3329515C2 (en) * 1983-08-16 1985-11-14 Krohne Meßtechnik GmbH & Co KG, 4100 Duisburg Electrical switching arrangement for a magnetic-inductive transducer
ZA845757B (en) * 1983-08-25 1985-04-24 Hoffmann La Roche Benzodiazepine derivatives
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
FI880814A (en) * 1987-03-10 1988-09-11 Hoffmann La Roche IMIDAZODIAZEPIN-derivate.
EP0698015A1 (en) * 1993-05-14 1996-02-28 Genentech, Inc. Preparation of n-cyanodithioimino-carbonates and 3-mercapto-5-amino-1h-1,2,4-triazole
IN184976B (en) * 1996-06-13 2000-10-14 Ranbaxy Lab Ltd
IT1399764B1 (en) * 2010-05-04 2013-05-03 F S I Fabbrica Italiana Sint PROCEDURE FOR THE SYNTHESIS OF 4H-IMIDAZO [1,5-A] [1,4] BENZODIAZEPINE, IN PARTICULAR OF MIDAZOLAM.
CN103086986B (en) * 2011-11-01 2015-11-04 上海医药工业研究院 The preparation method of Isosorbide-5-Nitrae-Benzodiazepine-N-nitrosamines intermediate and application thereof
CN103804384B (en) * 2014-01-27 2016-01-20 李宏 The preparation method of benzodiazepine compounds
PT3439665T (en) * 2016-03-18 2022-09-27 Uwm Res Foundation Inc Treatment of cognitive and mood symptoms in neurodegenerative and neuropsychiatric disorders with alpha5-containing gabaa receptor agonists
AU2017313753B2 (en) 2016-08-16 2022-01-27 The Trustees Of Columbia University In The City Of New York GABA(A) receptor modulators and methods to control airway hyperresponsiveness and inflammation in asthma
CN111410658B (en) * 2020-03-30 2021-03-26 江苏恩华药业股份有限公司 Impurity A and impurity B of midazolam or pharmaceutical composition thereof and application thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA716775B (en) * 1970-10-30 1972-06-28 Takeda Chemical Industries Ltd Benzodiazepine derivatives
DE2056265A1 (en) * 1970-11-16 1972-05-31 Sumitomo Chemical Co. Ltd., Osaka (Japan) Benzodiazepine derivs - from glycylamidobenzophenone derivs in dmso
JPS4932874B1 (en) * 1970-12-11 1974-09-03
BE787251A (en) * 1971-08-04 1973-02-05 Upjohn Co NEW BENZODIAZEPINES AND THEIR PREPARATION
BE790839A (en) * 1971-11-02 1973-04-30 Upjohn Co NEW BENZODIAZEPINES, THEIR PREPARATION PROCESS AND THE MEDICINAL PRODUCT CONTAINING THEM
BE792972A (en) * 1971-12-20 1973-06-19 Hoffmann La Roche BENZODIAZEPINE DERIVATIVES
FR2183716A1 (en) * 1972-05-05 1973-12-21 Centre Etd Ind Pharma Substd-6-phenyl-4h-imidazo (1,2-a)-1,4-benzo diazepines - - tranquillisers anxiolytics,sedatives and muscle-relaxants
CA1005443A (en) * 1972-06-22 1977-02-15 Michio Nakanishi Thienodiazepine compounds

Also Published As

Publication number Publication date
PL106563B1 (en) 1979-12-31
DD121640A5 (en) 1976-08-12
NO148188C (en) 1983-08-24
AU8470475A (en) 1977-03-17
GB1527131A (en) 1978-10-04
IE41844L (en) 1976-03-11
YU40267B (en) 1985-12-31
NO147109C (en) 1983-02-02
FI63234B (en) 1983-01-31
IE41844B1 (en) 1980-04-09
NL171060C (en) 1983-02-01
ZA755418B (en) 1977-06-29
KE3173A (en) 1982-01-08
FR2303016A1 (en) 1976-10-01
ES440850A1 (en) 1977-07-01
MY8200214A (en) 1982-12-31
PH16152A (en) 1983-07-12
NO147109B (en) 1982-10-25
AT360023B (en) 1980-12-10
NZ178635A (en) 1982-12-21
FR2303016B1 (en) 1982-07-09
LU73356A1 (en) 1977-05-11
SE7509991L (en) 1976-03-12
BE833248A (en) 1976-03-10
HK63381A (en) 1981-12-24
NL7510620A (en) 1976-03-15
ATA697775A (en) 1980-05-15
NO146573C (en) 1982-10-27
SU814278A3 (en) 1981-03-15
CH619953A5 (en) 1980-10-31
JPS51125099A (en) 1976-11-01
BR7505864A (en) 1976-08-03
DE2540522A1 (en) 1976-04-08
NO753069L (en) 1976-03-12
YU228575A (en) 1983-01-21
NO147914C (en) 1983-07-06
DK157615C (en) 1990-06-25
CU34346A (en) 1982-08-24
SE425785B (en) 1982-11-08
SE433080B (en) 1984-05-07
SE7902666L (en) 1979-03-23
AU505998B2 (en) 1979-12-13
IL48069A (en) 1980-09-16
DK157615B (en) 1990-01-29
FR2285890B1 (en) 1981-12-31
MX160600A (en) 1993-09-01
JPS562073B2 (en) 1981-01-17
FR2285890A1 (en) 1976-04-23
FI752517A (en) 1976-03-12
SE449098B (en) 1987-04-06
FI63234C (en) 1983-05-10
NO802718L (en) 1976-03-12
HU174752B (en) 1980-03-28
DK404175A (en) 1976-03-12
CA1067491A (en) 1979-12-04
NO148188B (en) 1983-05-16
SE7902667L (en) 1979-03-23
CU20892L (en) 1982-08-24
IL48069A0 (en) 1975-11-25
CH628053A5 (en) 1982-02-15
SE440504B (en) 1985-08-05
NO802719L (en) 1976-03-12
PH15091A (en) 1982-08-03
DE2540522C2 (en) 1988-10-20
NO147914B (en) 1983-03-28
NO146573B (en) 1982-07-19
SE7902668L (en) 1979-03-23

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