NO791806L - Fremgangsmaate for fremstilling av en ekstrakt av globularia - Google Patents
Fremgangsmaate for fremstilling av en ekstrakt av globulariaInfo
- Publication number
- NO791806L NO791806L NO791806A NO791806A NO791806L NO 791806 L NO791806 L NO 791806L NO 791806 A NO791806 A NO 791806A NO 791806 A NO791806 A NO 791806A NO 791806 L NO791806 L NO 791806L
- Authority
- NO
- Norway
- Prior art keywords
- globularia
- solvent
- water
- extraction
- extract
- Prior art date
Links
- 239000000284 extract Substances 0.000 title claims description 27
- 238000000034 method Methods 0.000 title claims description 17
- 241000981782 Globularia Species 0.000 title claims description 9
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 30
- 239000002904 solvent Substances 0.000 claims description 23
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 23
- 239000000047 product Substances 0.000 claims description 22
- 241000196324 Embryophyta Species 0.000 claims description 20
- 239000000203 mixture Substances 0.000 claims description 19
- 238000001914 filtration Methods 0.000 claims description 15
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 14
- 241001138444 Globularia alypum Species 0.000 claims description 13
- 238000000605 extraction Methods 0.000 claims description 13
- 239000002198 insoluble material Substances 0.000 claims description 13
- 238000001704 evaporation Methods 0.000 claims description 12
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 claims description 9
- 230000008020 evaporation Effects 0.000 claims description 9
- 238000004108 freeze drying Methods 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 8
- 241001138445 Globularia vulgaris Species 0.000 claims description 7
- 241000013557 Plantaginaceae Species 0.000 claims description 7
- 150000001298 alcohols Chemical class 0.000 claims description 7
- 239000000126 substance Substances 0.000 claims description 7
- 206010006500 Brucellosis Diseases 0.000 claims description 6
- 239000000706 filtrate Substances 0.000 claims description 5
- 150000002576 ketones Chemical class 0.000 claims description 5
- 238000010992 reflux Methods 0.000 claims description 5
- 241000894007 species Species 0.000 claims description 5
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims description 4
- 238000000889 atomisation Methods 0.000 claims description 4
- 229930195733 hydrocarbon Natural products 0.000 claims description 4
- 150000002430 hydrocarbons Chemical class 0.000 claims description 4
- 238000004809 thin layer chromatography Methods 0.000 claims description 4
- 238000004440 column chromatography Methods 0.000 claims description 3
- 150000002148 esters Chemical class 0.000 claims description 3
- 150000002170 ethers Chemical class 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 claims description 3
- 241000124008 Mammalia Species 0.000 claims description 2
- MHLMRBVCMNDOCW-UHFFFAOYSA-N acetic acid;butan-1-ol;hydrate Chemical compound O.CC(O)=O.CCCCO MHLMRBVCMNDOCW-UHFFFAOYSA-N 0.000 claims description 2
- 239000011230 binding agent Substances 0.000 claims description 2
- 239000001913 cellulose Substances 0.000 claims description 2
- 229920002678 cellulose Polymers 0.000 claims description 2
- 238000004587 chromatography analysis Methods 0.000 claims description 2
- 235000013399 edible fruits Nutrition 0.000 claims description 2
- 150000008282 halocarbons Chemical class 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 238000000746 purification Methods 0.000 claims description 2
- 239000001117 sulphuric acid Substances 0.000 claims description 2
- 230000001225 therapeutic effect Effects 0.000 claims description 2
- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 claims description 2
- FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 claims description 2
- 235000012141 vanillin Nutrition 0.000 claims description 2
- 241000303838 Lobularia Species 0.000 claims 2
- 235000011465 Lobularia Nutrition 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 description 9
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 5
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 5
- 239000012153 distilled water Substances 0.000 description 4
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 description 3
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- 241000191967 Staphylococcus aureus Species 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 description 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
- 239000003960 organic solvent Substances 0.000 description 3
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- RGSFGYAAUTVSQA-UHFFFAOYSA-N Cyclopentane Chemical compound C1CCCC1 RGSFGYAAUTVSQA-UHFFFAOYSA-N 0.000 description 2
- LCGLNKUTAGEVQW-UHFFFAOYSA-N Dimethyl ether Chemical compound COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- OFBQJSOFQDEBGM-UHFFFAOYSA-N Pentane Chemical compound CCCCC OFBQJSOFQDEBGM-UHFFFAOYSA-N 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 229920005654 Sephadex Polymers 0.000 description 2
- 239000012507 Sephadex™ Substances 0.000 description 2
- 239000002260 anti-inflammatory agent Substances 0.000 description 2
- 230000003385 bacteriostatic effect Effects 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000003480 eluent Substances 0.000 description 2
- 239000003456 ion exchange resin Substances 0.000 description 2
- 229920003303 ion-exchange polymer Polymers 0.000 description 2
- 239000008141 laxative Substances 0.000 description 2
- 230000002475 laxative effect Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- XNLICIUVMPYHGG-UHFFFAOYSA-N pentan-2-one Chemical compound CCCC(C)=O XNLICIUVMPYHGG-UHFFFAOYSA-N 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 1
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 1
- 241000589562 Brucella Species 0.000 description 1
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 description 1
- ZAFNJMIOTHYJRJ-UHFFFAOYSA-N Diisopropyl ether Chemical compound CC(C)OC(C)C ZAFNJMIOTHYJRJ-UHFFFAOYSA-N 0.000 description 1
- 241000194031 Enterococcus faecium Species 0.000 description 1
- 201000005569 Gout Diseases 0.000 description 1
- 208000028018 Lymphocytic leukaemia Diseases 0.000 description 1
- 241000288049 Perdix perdix Species 0.000 description 1
- 241000224016 Plasmodium Species 0.000 description 1
- 229960001138 acetylsalicylic acid Drugs 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 230000001741 anti-phlogistic effect Effects 0.000 description 1
- 239000003430 antimalarial agent Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 239000000022 bacteriostatic agent Substances 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000003113 dilution method Methods 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 208000028104 epidemic louse-borne typhus Diseases 0.000 description 1
- -1 ethyl acetate) Chemical class 0.000 description 1
- 229940124600 folk medicine Drugs 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- DMEGYFMYUHOHGS-UHFFFAOYSA-N heptamethylene Natural products C1CCCCCC1 DMEGYFMYUHOHGS-UHFFFAOYSA-N 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 208000003747 lymphoid leukemia Diseases 0.000 description 1
- GBMDVOWEEQVZKZ-UHFFFAOYSA-N methanol;hydrate Chemical compound O.OC GBMDVOWEEQVZKZ-UHFFFAOYSA-N 0.000 description 1
- 210000005170 neoplastic cell Anatomy 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 238000009519 pharmacological trial Methods 0.000 description 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 206010061393 typhus Diseases 0.000 description 1
- 239000000083 urinary anti-infective agent Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/18—Water
- G01N33/1813—Specific cations in water, e.g. heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Plant Substances (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2561978 | 1978-05-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO791806L true NO791806L (no) | 1979-12-03 |
Family
ID=10230602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO791806A NO791806L (no) | 1978-05-31 | 1979-05-30 | Fremgangsmaate for fremstilling av en ekstrakt av globularia |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0006059A1 (fi) |
| JP (1) | JPS5527170A (fi) |
| AU (1) | AU4763279A (fi) |
| DK (1) | DK226079A (fi) |
| ES (1) | ES481169A1 (fi) |
| FI (1) | FI791751A (fi) |
| GR (1) | GR65291B (fi) |
| IL (1) | IL57455A0 (fi) |
| MA (1) | MA18461A1 (fi) |
| NO (1) | NO791806L (fi) |
| OA (1) | OA06266A (fi) |
| PT (1) | PT69702A (fi) |
| ZA (1) | ZA792681B (fi) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2970868B1 (fr) | 2011-01-31 | 2023-10-27 | Sederma Sa | Extrait d'origine vegetale, composition le contenant, procede d'obtention par culture vegetale et utilisations dans les domaines cosmetique, pharmaceutique et cosmeceutique |
-
1979
- 1979-05-29 EP EP79400338A patent/EP0006059A1/fr not_active Withdrawn
- 1979-05-30 DK DK226079A patent/DK226079A/da unknown
- 1979-05-30 PT PT69702A patent/PT69702A/pt unknown
- 1979-05-30 GR GR59237A patent/GR65291B/el unknown
- 1979-05-30 NO NO791806A patent/NO791806L/no unknown
- 1979-05-30 ZA ZA792681A patent/ZA792681B/xx unknown
- 1979-05-31 AU AU47632/79A patent/AU4763279A/en not_active Abandoned
- 1979-05-31 ES ES481169A patent/ES481169A1/es not_active Expired
- 1979-05-31 MA MA18655A patent/MA18461A1/fr unknown
- 1979-05-31 JP JP6807879A patent/JPS5527170A/ja active Pending
- 1979-05-31 IL IL57455A patent/IL57455A0/xx unknown
- 1979-05-31 OA OA56819A patent/OA06266A/xx unknown
- 1979-05-31 FI FI791751A patent/FI791751A/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| FI791751A (fi) | 1979-12-01 |
| EP0006059A1 (fr) | 1979-12-12 |
| ES481169A1 (es) | 1980-08-16 |
| OA06266A (fr) | 1981-06-30 |
| PT69702A (en) | 1979-06-01 |
| AU4763279A (en) | 1979-12-06 |
| ZA792681B (en) | 1980-08-27 |
| DK226079A (da) | 1979-12-01 |
| GR65291B (en) | 1980-08-01 |
| IL57455A0 (en) | 1979-09-30 |
| MA18461A1 (fr) | 1979-12-31 |
| JPS5527170A (en) | 1980-02-27 |
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