NO750696L - - Google Patents
Info
- Publication number
- NO750696L NO750696L NO750696*[A NO750696A NO750696L NO 750696 L NO750696 L NO 750696L NO 750696 A NO750696 A NO 750696A NO 750696 L NO750696 L NO 750696L
- Authority
- NO
- Norway
- Prior art keywords
- formula
- compound
- acetic acid
- methyl
- nitro
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 claims description 10
- 150000002168 ethanoic acid esters Chemical class 0.000 claims description 7
- 229910052739 hydrogen Chemical group 0.000 claims description 7
- 239000001257 hydrogen Chemical group 0.000 claims description 7
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
- 230000000844 anti-bacterial effect Effects 0.000 claims description 5
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 4
- 230000000842 anti-protozoal effect Effects 0.000 claims description 4
- 230000001857 anti-mycotic effect Effects 0.000 claims description 3
- 238000010992 reflux Methods 0.000 claims description 3
- 229960000583 acetic acid Drugs 0.000 claims description 2
- 239000002543 antimycotic Substances 0.000 claims description 2
- 239000003904 antiprotozoal agent Substances 0.000 claims description 2
- 238000009835 boiling Methods 0.000 claims description 2
- 239000012362 glacial acetic acid Substances 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims description 2
- 239000002904 solvent Substances 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 claims 1
- 238000011282 treatment Methods 0.000 description 9
- 229940079593 drug Drugs 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 125000004494 ethyl ester group Chemical group 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- FOOYVUKWJKLDLX-UHFFFAOYSA-N 2-[(5-nitro-1h-imidazol-2-yl)methylidene]-3-oxobutanoic acid Chemical class CC(=O)C(C(O)=O)=CC1=NC=C([N+]([O-])=O)N1 FOOYVUKWJKLDLX-UHFFFAOYSA-N 0.000 description 2
- FUBFWTUFPGFHOJ-UHFFFAOYSA-N 2-nitrofuran Chemical class [O-][N+](=O)C1=CC=CO1 FUBFWTUFPGFHOJ-UHFFFAOYSA-N 0.000 description 2
- 206010001598 Alcohol intolerance Diseases 0.000 description 2
- 241000700159 Rattus Species 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 230000002496 gastric effect Effects 0.000 description 2
- 238000002329 infrared spectrum Methods 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- SRQKTCXJCCHINN-NYYWCZLTSA-N nifuratel Chemical compound O=C1OC(CSC)CN1\N=C\C1=CC=C([N+]([O-])=O)O1 SRQKTCXJCCHINN-NYYWCZLTSA-N 0.000 description 2
- 229960002136 nifuratel Drugs 0.000 description 2
- 230000000474 nursing effect Effects 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 230000002963 trichomonacidal effect Effects 0.000 description 2
- 241000222122 Candida albicans Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 241000224526 Trichomonas Species 0.000 description 1
- 241000224527 Trichomonas vaginalis Species 0.000 description 1
- 230000000843 anti-fungal effect Effects 0.000 description 1
- 229940058965 antiprotozoal agent against amoebiasis and other protozoal diseases nitroimidazole derivative Drugs 0.000 description 1
- 229940027988 antiseptic and disinfectant nitrofuran derivative Drugs 0.000 description 1
- 230000002238 attenuated effect Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 239000007903 gelatin capsule Chemical group 0.000 description 1
- 230000002489 hematologic effect Effects 0.000 description 1
- 150000002460 imidazoles Chemical class 0.000 description 1
- 229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 238000011866 long-term treatment Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- VAOCPAMSLUNLGC-UHFFFAOYSA-N metronidazole Chemical group CC1=NC=C([N+]([O-])=O)N1CCO VAOCPAMSLUNLGC-UHFFFAOYSA-N 0.000 description 1
- 229960000282 metronidazole Drugs 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 231100000417 nephrotoxicity Toxicity 0.000 description 1
- IAIWVQXQOWNYOU-FPYGCLRLSA-N nitrofural Chemical class NC(=O)N\N=C\C1=CC=C([N+]([O-])=O)O1 IAIWVQXQOWNYOU-FPYGCLRLSA-N 0.000 description 1
- 150000004957 nitroimidazoles Chemical class 0.000 description 1
- 239000002674 ointment Chemical group 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000000843 powder Chemical group 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000003826 tablet Chemical group 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT4893074 | 1974-03-04 | ||
| IT2957774A IT1050709B (it) | 1974-11-19 | 1974-11-19 | Composti chimici per il trattamento di forme di candidiosi |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO750696L true NO750696L (de) | 1975-09-05 |
Family
ID=26328845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO750696*[A NO750696L (de) | 1974-03-04 | 1975-03-03 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US3960882A (de) |
| JP (1) | JPS50121278A (de) |
| AR (1) | AR204031A1 (de) |
| CA (1) | CA1028711A (de) |
| CH (1) | CH605812A5 (de) |
| DD (1) | DD118429A5 (de) |
| DE (1) | DE2506256C2 (de) |
| DK (1) | DK83775A (de) |
| ES (1) | ES434872A1 (de) |
| FI (1) | FI750612A (de) |
| FR (1) | FR2262983B1 (de) |
| GB (1) | GB1476863A (de) |
| NL (1) | NL7502566A (de) |
| NO (1) | NO750696L (de) |
| PH (1) | PH10947A (de) |
| SE (1) | SE7502290L (de) |
| YU (1) | YU36704B (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2025934B (en) * | 1978-06-22 | 1982-08-04 | Grissmann Chem Ltd | (1 - alkyl - 5 - nitro - 2 - imidozolyl)-vinylglyoxal-diacetals their preparation and their use |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3702330A (en) * | 1970-10-05 | 1972-11-07 | Merck & Co Inc | Imidazolyl acrylic acid derivatives |
| JPS551258B2 (de) * | 1972-05-13 | 1980-01-12 |
-
1975
- 1975-01-01 AR AR257808A patent/AR204031A1/es active
- 1975-02-10 US US05/548,739 patent/US3960882A/en not_active Expired - Lifetime
- 1975-02-10 GB GB557375A patent/GB1476863A/en not_active Expired
- 1975-02-14 DE DE2506256A patent/DE2506256C2/de not_active Expired
- 1975-02-19 ES ES434872A patent/ES434872A1/es not_active Expired
- 1975-02-21 JP JP50021056A patent/JPS50121278A/ja active Pending
- 1975-02-25 YU YU0456/75A patent/YU36704B/xx unknown
- 1975-02-28 CH CH258975A patent/CH605812A5/xx not_active IP Right Cessation
- 1975-02-28 PH PH16846A patent/PH10947A/en unknown
- 1975-02-28 SE SE7502290A patent/SE7502290L/xx unknown
- 1975-03-03 NO NO750696*[A patent/NO750696L/no unknown
- 1975-03-03 CA CA221,094A patent/CA1028711A/en not_active Expired
- 1975-03-03 DD DD184513A patent/DD118429A5/xx unknown
- 1975-03-03 DK DK83775*#A patent/DK83775A/da unknown
- 1975-03-04 FR FR7506763A patent/FR2262983B1/fr not_active Expired
- 1975-03-04 NL NL7502566A patent/NL7502566A/xx not_active Application Discontinuation
- 1975-03-04 FI FI750612A patent/FI750612A/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE2506256C2 (de) | 1982-09-16 |
| SE7502290L (de) | 1975-09-05 |
| ES434872A1 (es) | 1977-03-01 |
| FR2262983A1 (de) | 1975-10-03 |
| FR2262983B1 (de) | 1978-07-28 |
| PH10947A (en) | 1977-10-05 |
| JPS50121278A (de) | 1975-09-23 |
| YU36704B (en) | 1984-08-31 |
| DE2506256A1 (de) | 1975-09-11 |
| YU45675A (en) | 1982-06-18 |
| CH605812A5 (de) | 1978-10-13 |
| AU7834375A (en) | 1976-08-19 |
| NL7502566A (nl) | 1975-09-08 |
| US3960882A (en) | 1976-06-01 |
| CA1028711A (en) | 1978-03-28 |
| AR204031A1 (es) | 1975-11-12 |
| GB1476863A (en) | 1977-06-16 |
| FI750612A (de) | 1975-09-05 |
| DK83775A (de) | 1975-09-05 |
| DD118429A5 (de) | 1976-03-05 |
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