NO341910B1 - Fremgangsmåter for diagnostisering av genetiske varianter i genet tcf7l2 som diagnostiske markører for økt eller redusert mottakelighet for type 2 diabetes mellitus - Google Patents
Fremgangsmåter for diagnostisering av genetiske varianter i genet tcf7l2 som diagnostiske markører for økt eller redusert mottakelighet for type 2 diabetes mellitus Download PDFInfo
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- NO341910B1 NO341910B1 NO20080389A NO20080389A NO341910B1 NO 341910 B1 NO341910 B1 NO 341910B1 NO 20080389 A NO20080389 A NO 20080389A NO 20080389 A NO20080389 A NO 20080389A NO 341910 B1 NO341910 B1 NO 341910B1
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- diabetes
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| US69217405P | 2005-06-20 | 2005-06-20 | |
| US75715506P | 2006-01-06 | 2006-01-06 | |
| PCT/IS2006/000014 WO2006137085A1 (en) | 2005-06-20 | 2006-06-16 | Genetic variants in the tcf7l2 gene as diagnostic markers for risk of type 2 diabetes mellitus |
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| NO20080389L NO20080389L (no) | 2008-01-21 |
| NO341910B1 true NO341910B1 (no) | 2018-02-19 |
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| US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
| US7501426B2 (en) | 2004-02-18 | 2009-03-10 | Boehringer Ingelheim International Gmbh | 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions |
| DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
| KR101374304B1 (ko) * | 2005-06-20 | 2014-03-14 | 디코드 제네틱스 이에이치에프 | 타입 2 당뇨병의 위험에 대한 진단 마커인 ｔｃｆ7ｌ2유전자의 유전적 변이체 |
| DE102005035891A1 (de) | 2005-07-30 | 2007-02-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel |
| EP1852108A1 (en) | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | DPP IV inhibitor formulations |
| EP2540725A1 (de) | 2006-05-04 | 2013-01-02 | Boehringer Ingelheim International GmbH | Polymorphe von 1-((4-Methyl-chinazolin-2-yl)methyl)-3-methyl-7-(2-butin-1-yl)-8-(3-(R)-amino-piperidin-1-yl)xanthin |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| US20100086921A1 (en) * | 2006-11-30 | 2010-04-08 | Valgerdur Steinthorsdottir | Genetic susceptibility variants of type 2 diabetes mellitus |
| EP2057183A2 (en) * | 2007-03-01 | 2009-05-13 | Novetide Ltd. | High purity peptides |
| EP2155903A4 (en) * | 2007-04-30 | 2010-12-01 | Compugen Ltd | ALLELIC POLYMORPHISM ASSOCIATED WITH DIABETES |
| PE20091730A1 (es) | 2008-04-03 | 2009-12-10 | Boehringer Ingelheim Int | Formulaciones que comprenden un inhibidor de dpp4 |
| BRPI0916997A2 (pt) | 2008-08-06 | 2020-12-15 | Boehringer Ingelheim International Gmbh | Inibidor de dpp-4 e seu uso |
| UY32030A (es) | 2008-08-06 | 2010-03-26 | Boehringer Ingelheim Int | "tratamiento para diabetes en pacientes inapropiados para terapia con metformina" |
| JP2012502081A (ja) | 2008-09-10 | 2012-01-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 糖尿病及び関連症状の治療のための組み合わせ治療 |
| US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
| MX2011006713A (es) | 2008-12-23 | 2011-07-13 | Boehringer Ingelheim Int | Formas salinas de compuesto organico. |
| TW201036975A (en) | 2009-01-07 | 2010-10-16 | Boehringer Ingelheim Int | Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy |
| US8796182B2 (en) | 2009-07-10 | 2014-08-05 | Decode Genetics Ehf. | Genetic markers associated with risk of diabetes mellitus |
| KR20120107080A (ko) * | 2009-11-27 | 2012-09-28 | 베링거 인겔하임 인터내셔날 게엠베하 | 리나글립틴과 같은 ｄｐｐ－ｉｖ 억제제를 사용한 유전자형 검사된 당뇨병 환자의 치료 |
| CN107961377B (zh) | 2010-05-05 | 2022-11-22 | 勃林格殷格翰国际有限公司 | 组合疗法 |
| KR20130093012A (ko) | 2010-06-24 | 2013-08-21 | 베링거 인겔하임 인터내셔날 게엠베하 | 당뇨병 요법 |
| US9034883B2 (en) | 2010-11-15 | 2015-05-19 | Boehringer Ingelheim International Gmbh | Vasoprotective and cardioprotective antidiabetic therapy |
| EP3517539B1 (en) | 2011-07-15 | 2022-12-14 | Boehringer Ingelheim International GmbH | Substituted dimeric quinazoline derivative, its preparation and its use in pharmaceutical compositions for the treatment of type i and ii diabetes |
| US9555001B2 (en) | 2012-03-07 | 2017-01-31 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition and uses thereof |
| EP3685839A1 (en) | 2012-05-14 | 2020-07-29 | Boehringer Ingelheim International GmbH | Linagliptin for use in the treatment of albuminuria and kidney related diseases |
| WO2013171166A1 (en) | 2012-05-14 | 2013-11-21 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp-4 inhibitor for use in the treatment of sirs and/or sepsis |
| WO2013174767A1 (en) | 2012-05-24 | 2013-11-28 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference |
| EP2971163A4 (en) * | 2013-03-14 | 2017-03-22 | The Children's Hospital of Philadelphia | Tcf7l2 variant and methods of use thereof in diagnostic and drug screening assays |
| RU2521202C1 (ru) * | 2013-04-12 | 2014-06-27 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Белгородский государственный национальный исследовательский университет" | Способ прогнозирования риска развития сахарного диабета второго типа у больных гипертонической болезнью |
| JP6615109B2 (ja) | 2014-02-28 | 2019-12-04 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｄｐｐ−４阻害薬の医学的使用 |
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| WO2016201438A1 (en) * | 2015-06-11 | 2016-12-15 | The Children's Hospital Of Philadelphia | New targets modulated by a casual variant of type 2 diabetes (t2d) embedded within the tcf7l2 gene and methods of use thereof for identifying agents having efficacy for the treatment of type 2 diabetes and other metabolic disorders |
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| CN109182508A (zh) * | 2018-10-22 | 2019-01-11 | 北京华夏时代生物工程有限公司 | Tcf7l2基因单核苷酸多态性的荧光原位杂交测序方法 |
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2006
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- 2006-06-16 JP JP2008517701A patent/JP5301987B2/ja not_active Expired - Fee Related
- 2006-06-16 CN CN2006800221296A patent/CN101238222B/zh not_active Expired - Fee Related
- 2006-06-16 BR BRPI0612301-5A patent/BRPI0612301A2/pt not_active Application Discontinuation
- 2006-06-16 CA CA2612475A patent/CA2612475C/en active Active
- 2006-06-16 US US11/454,296 patent/US7585630B2/en active Active
- 2006-06-16 WO PCT/IS2006/000014 patent/WO2006137085A1/en not_active Ceased
- 2006-06-16 EA EA200800087A patent/EA016397B1/ru not_active IP Right Cessation
- 2006-06-16 MX MX2007015848A patent/MX2007015848A/es active IP Right Grant
- 2006-06-16 NZ NZ564285A patent/NZ564285A/en not_active IP Right Cessation
- 2006-06-16 EP EP06745230.0A patent/EP1907569B1/en active Active
- 2006-06-16 AU AU2006260477A patent/AU2006260477B2/en not_active Ceased
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-
2008
- 2008-01-21 NO NO20080389A patent/NO341910B1/no not_active IP Right Cessation
-
2009
- 2009-06-15 US US12/456,381 patent/US20090275043A1/en not_active Abandoned
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2011
- 2011-11-11 US US13/294,802 patent/US20120149016A1/en not_active Abandoned
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| DATABASE EMBL EBI; 1998.09.16, MAHARAIS ER AL,: "HS_3076_B1_H08_MR CIT approved human genomic sperm library D homo sapiens genomic clone Plate=3076 Col=15 Row=P" hentet fra http://www.ebi.ac.uk, Database accession no. AQ166288, Dated: 01.01.0001 * |
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Also Published As
| Publication number | Publication date |
|---|---|
| KR101374304B1 (ko) | 2014-03-14 |
| HK1117569A1 (en) | 2009-01-16 |
| AU2006260477A8 (en) | 2006-12-28 |
| NO20080389L (no) | 2008-01-21 |
| CN101238222B (zh) | 2013-04-10 |
| EP1907569A1 (en) | 2008-04-09 |
| EA200800087A1 (ru) | 2008-06-30 |
| AU2006260477B2 (en) | 2012-02-23 |
| KR20080051128A (ko) | 2008-06-10 |
| CN101238222A (zh) | 2008-08-06 |
| US20120149016A1 (en) | 2012-06-14 |
| JP5301987B2 (ja) | 2013-09-25 |
| US7585630B2 (en) | 2009-09-08 |
| NZ564285A (en) | 2010-03-26 |
| MX2007015848A (es) | 2008-04-22 |
| EP1907569B1 (en) | 2013-04-10 |
| JP2008546403A (ja) | 2008-12-25 |
| BRPI0612301A2 (pt) | 2009-01-27 |
| EA016397B1 (ru) | 2012-04-30 |
| AU2006260477A1 (en) | 2006-12-28 |
| US20090275043A1 (en) | 2009-11-05 |
| IL188147A (en) | 2013-02-28 |
| CA2612475A1 (en) | 2006-12-28 |
| WO2006137085A1 (en) | 2006-12-28 |
| US20060286588A1 (en) | 2006-12-21 |
| CA2612475C (en) | 2015-07-28 |
| IL188147A0 (en) | 2008-03-20 |
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