NO333805B1 - Anvendelse av 4-hydroxy tamoxifen for fremstilling av et medikament, og farmasoytiske sammensetninger - Google Patents
Anvendelse av 4-hydroxy tamoxifen for fremstilling av et medikament, og farmasoytiske sammensetninger Download PDFInfo
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- NO333805B1 NO333805B1 NO20054526A NO20054526A NO333805B1 NO 333805 B1 NO333805 B1 NO 333805B1 NO 20054526 A NO20054526 A NO 20054526A NO 20054526 A NO20054526 A NO 20054526A NO 333805 B1 NO333805 B1 NO 333805B1
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- hydroxy tamoxifen
- tamoxifen
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45896303P | 2003-04-01 | 2003-04-01 | |
| PCT/EP2003/015029 WO2004087123A1 (en) | 2003-04-01 | 2003-12-15 | Prevention and treatment of breast cancer with 4-hydroxy tamoxifen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20054526L NO20054526L (no) | 2005-09-30 |
| NO333805B1 true NO333805B1 (no) | 2013-09-16 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20054526A NO333805B1 (no) | 2003-04-01 | 2005-09-30 | Anvendelse av 4-hydroxy tamoxifen for fremstilling av et medikament, og farmasoytiske sammensetninger |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7704516B2 (he) |
| EP (3) | EP1608353B1 (he) |
| JP (1) | JP5490346B2 (he) |
| AU (1) | AU2003294973B2 (he) |
| CA (1) | CA2519980C (he) |
| ES (3) | ES2456958T3 (he) |
| HK (2) | HK1119950A1 (he) |
| IL (1) | IL170807A (he) |
| MX (1) | MXPA05010597A (he) |
| NO (1) | NO333805B1 (he) |
| NZ (1) | NZ542499A (he) |
| WO (1) | WO2004087123A1 (he) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2050443B1 (en) * | 2002-12-18 | 2017-05-24 | Besins Healthcare Luxembourg SARL | Reduction of breast density with 4-hydroxy tamoxifen |
| EP1572178B1 (en) * | 2002-12-18 | 2006-05-03 | Laboratoires Besins International | Treatment of mastalgia with 4-hydroxy tamoxifen |
| US7704516B2 (en) * | 2003-04-01 | 2010-04-27 | Laboratories Besins International Sa | Percutaneous composition comprising 4-hydroxy tamoxifen |
| AU2004246812B8 (en) * | 2003-06-09 | 2010-01-14 | Besins Healthcare Luxembourg Sarl | Treatment and prevention of excessive scarring with 4-hydroxy tamoxifen |
| US7968532B2 (en) * | 2003-12-15 | 2011-06-28 | Besins Healthcare Luxembourg | Treatment of gynecomastia with 4-hydroxy tamoxifen |
| MXPA06010914A (es) * | 2004-03-22 | 2006-12-15 | Besins Int Lab | Tratamiento y prevencion de enfermedades de mama benigna con 4-hidroxi tamoxifen. |
| US20050208139A1 (en) * | 2004-03-22 | 2005-09-22 | Ascend Therapeutics, Inc. | Chemically stable compositions of 4-hydroxy tamoxifen |
| US7507769B2 (en) * | 2004-03-22 | 2009-03-24 | Laboratoires Besins International | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen |
| EP1579856A1 (en) * | 2004-03-22 | 2005-09-28 | Laboratoires Besins International | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen |
| DE602005011314D1 (de) * | 2004-10-14 | 2009-01-08 | Besins Int Lab | 4-hydroxytamoxifengel-formulierungen |
| EP1647271A1 (en) * | 2004-10-14 | 2006-04-19 | Laboratoires Besins International | 4-Hydroxy tamoxifen gel formulations |
| EP2147674A1 (en) * | 2008-07-24 | 2010-01-27 | Besins Healthcare | Transdermal pharmaceutical compositions comprising danazol |
| US10080760B2 (en) * | 2009-10-27 | 2018-09-25 | Besins Healthcare Luxembourg Sarl | Transdermal pharmaceutical compositions comprising active agents |
| EP4220178A3 (en) * | 2014-05-12 | 2023-08-16 | Quest Diagnostics Investments Incorporated | Quantitation of tamoxifen and metabolites thereof by mass spectrometry |
| KR101571098B1 (ko) | 2014-07-16 | 2015-11-23 | 건국대학교 산학협력단 | 타목시펜 및 메틸설포닐메탄을 유효성분으로 포함하는 암 질환 예방 또는 치료용 약학 조성물 |
| CN106459704B (zh) * | 2014-08-27 | 2020-08-25 | 东洋纺株式会社 | 低介电性粘合剂组合物 |
| WO2016094854A2 (en) * | 2014-12-12 | 2016-06-16 | Miradx | Methods for treating or preventing cancer in a kras-variant patient and for diagnosing risk of developing multiple primary breast tumors |
| PL3449017T3 (pl) | 2016-04-29 | 2022-06-27 | Board Of Regents, The University Of Texas System | Ukierunkowane pomiary aktywności transkrypcyjnej związanej z receptorami hormonów |
| SG11202002105WA (en) | 2017-09-11 | 2020-04-29 | Atossa Therapeutics Inc | Methods for making and using endoxifen |
| WO2019172109A1 (ja) | 2018-03-07 | 2019-09-12 | 東亞合成株式会社 | 接着剤組成物及びこれを用いた接着剤層付き積層体 |
| WO2020023616A1 (en) * | 2018-07-24 | 2020-01-30 | Cornell University | Methods of upregulating tiparp as anticancer strategies |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2558373B1 (fr) * | 1984-01-20 | 1987-07-03 | Mauvais Jarvis Pierre | Medicament antioestrogene a base de 4-hydroxytamoxifene pour administration percutanee |
| DE3781546D1 (de) * | 1987-04-21 | 1992-10-08 | Heumann Pharma Gmbh & Co | Stabile loesungsmitteladdukte von z-1-(p-beta-dimethylamino-ethoxyphenyl)-1-(p-hydroxyphenyl)-2-phenylbut-1-en. |
| US5045553A (en) * | 1987-06-24 | 1991-09-03 | Fujisawa Pharmaceutical Company, Ltd. | Pharmaceutical composition for percutaneous drug absorption and percutaneous drug absorption promoter |
| DE3836862A1 (de) | 1988-10-27 | 1990-05-03 | Schering Ag | Mittel zur transdermalen applikation von steroidhormonen |
| US5189212A (en) * | 1990-09-07 | 1993-02-23 | University Of Georgia Research Foundation, Inc. | Triarylethylene carboxylic acids with estrogenic activity |
| TW218849B (he) * | 1991-05-17 | 1994-01-11 | Bristol Myers Squibb Co | |
| US5613958A (en) | 1993-05-12 | 1997-03-25 | Pp Holdings Inc. | Transdermal delivery systems for the modulated administration of drugs |
| DE4407742C1 (de) | 1994-03-08 | 1995-06-22 | Hexal Pharma Gmbh | Transdermales System in Form eines Pflasters mit einem Tamoxifen-Derivat |
| US5720963A (en) * | 1994-08-26 | 1998-02-24 | Mary Kay Inc. | Barrier disruption treatments for structurally deteriorated skin |
| JP2001500841A (ja) | 1996-03-29 | 2001-01-23 | エス ヴェー パテントフェアヴェアツングス ゲゼルシャフト ミット ベシュレンクテル ハフツンク | 障害された皮下結合脂肪組織、とりわけ脂肪性浮腫の場合における皮膚を引きしめ滑らかにするための化粧品および化粧用組成物 |
| EP1043986B1 (en) | 1997-12-23 | 2003-04-16 | Hexal Ag | Mixture and pharmaceutical composition comprising z-4-hydroxytamoxifen and cyclodextrin |
| US6013270A (en) * | 1998-04-20 | 2000-01-11 | The Procter & Gamble Company | Skin care kit |
| WO2001043775A2 (en) | 1999-12-16 | 2001-06-21 | Dermatrends, Inc. | Hydroxide-releasing agents as skin permeation enhancers |
| DE10033853A1 (de) | 2000-07-12 | 2002-01-31 | Hexal Ag | Transdermales therapeutisches System mit hochdispersem Siliziumdioxid |
| US20040198706A1 (en) * | 2003-03-11 | 2004-10-07 | Carrara Dario Norberto R. | Methods and formulations for transdermal or transmucosal application of active agents |
| US6503894B1 (en) | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
| AU2002340120A1 (en) * | 2001-10-04 | 2003-04-14 | Cellegy Pharmaceuticals, Inc. | Semisolid topical hormonal compositions and methods for treatment |
| EP1317921B1 (fr) | 2001-12-07 | 2009-08-19 | Besins International Belgique | Composition pharmaceutique sous forme de gel ou de solution à base de dihydrotestostérone, son procédé de préparation et ses utilisations |
| EP1572178B1 (en) * | 2002-12-18 | 2006-05-03 | Laboratoires Besins International | Treatment of mastalgia with 4-hydroxy tamoxifen |
| EP2050443B1 (en) * | 2002-12-18 | 2017-05-24 | Besins Healthcare Luxembourg SARL | Reduction of breast density with 4-hydroxy tamoxifen |
| US7704516B2 (en) * | 2003-04-01 | 2010-04-27 | Laboratories Besins International Sa | Percutaneous composition comprising 4-hydroxy tamoxifen |
| AU2004246812B8 (en) | 2003-06-09 | 2010-01-14 | Besins Healthcare Luxembourg Sarl | Treatment and prevention of excessive scarring with 4-hydroxy tamoxifen |
| US7968532B2 (en) | 2003-12-15 | 2011-06-28 | Besins Healthcare Luxembourg | Treatment of gynecomastia with 4-hydroxy tamoxifen |
| US7507769B2 (en) * | 2004-03-22 | 2009-03-24 | Laboratoires Besins International | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen |
| EP1579856A1 (en) | 2004-03-22 | 2005-09-28 | Laboratoires Besins International | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen |
| US20050208139A1 (en) | 2004-03-22 | 2005-09-22 | Ascend Therapeutics, Inc. | Chemically stable compositions of 4-hydroxy tamoxifen |
| EP1647271A1 (en) | 2004-10-14 | 2006-04-19 | Laboratoires Besins International | 4-Hydroxy tamoxifen gel formulations |
-
2003
- 2003-12-15 US US10/734,638 patent/US7704516B2/en not_active Expired - Lifetime
- 2003-12-15 EP EP03785958.4A patent/EP1608353B1/en not_active Expired - Lifetime
- 2003-12-15 EP EP08103007.4A patent/EP1952810B1/en not_active Expired - Lifetime
- 2003-12-15 AU AU2003294973A patent/AU2003294973B2/en not_active Expired
- 2003-12-15 MX MXPA05010597A patent/MXPA05010597A/es active IP Right Grant
- 2003-12-15 ES ES08103014.0T patent/ES2456958T3/es not_active Expired - Lifetime
- 2003-12-15 WO PCT/EP2003/015029 patent/WO2004087123A1/en active Application Filing
- 2003-12-15 CA CA2519980A patent/CA2519980C/en not_active Expired - Lifetime
- 2003-12-15 ES ES03785958.4T patent/ES2483896T3/es not_active Expired - Lifetime
- 2003-12-15 EP EP08103014.0A patent/EP1941871B1/en not_active Expired - Lifetime
- 2003-12-15 ES ES08103007.4T patent/ES2456957T3/es not_active Expired - Lifetime
- 2003-12-15 NZ NZ542499A patent/NZ542499A/en not_active IP Right Cessation
- 2003-12-15 JP JP2004570040A patent/JP5490346B2/ja not_active Expired - Lifetime
-
2005
- 2005-09-12 IL IL170807A patent/IL170807A/he active IP Right Grant
- 2005-09-30 NO NO20054526A patent/NO333805B1/no not_active IP Right Cessation
-
2006
- 2006-06-28 HK HK08113909.5A patent/HK1119950A1/xx not_active IP Right Cessation
- 2006-06-28 HK HK06107310.2A patent/HK1086193A1/xx not_active IP Right Cessation
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2009
- 2009-01-14 US US12/353,890 patent/US8475814B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP1608353B1 (en) | 2014-04-30 |
| JP5490346B2 (ja) | 2014-05-14 |
| NZ542499A (en) | 2008-10-31 |
| EP1608353A1 (en) | 2005-12-28 |
| HK1086193A1 (en) | 2006-09-15 |
| ES2456958T3 (es) | 2014-04-24 |
| JP2006514967A (ja) | 2006-05-18 |
| MXPA05010597A (es) | 2006-03-09 |
| EP1952810A1 (en) | 2008-08-06 |
| US20090186944A1 (en) | 2009-07-23 |
| CA2519980C (en) | 2012-04-10 |
| NO20054526L (no) | 2005-09-30 |
| IL170807A (he) | 2014-08-31 |
| EP1941871B1 (en) | 2014-01-08 |
| WO2004087123A1 (en) | 2004-10-14 |
| US8475814B2 (en) | 2013-07-02 |
| ES2483896T3 (es) | 2014-08-08 |
| CA2519980A1 (en) | 2004-10-14 |
| EP1952810B1 (en) | 2014-01-08 |
| US20050031695A1 (en) | 2005-02-10 |
| US7704516B2 (en) | 2010-04-27 |
| AU2003294973B2 (en) | 2010-05-13 |
| ES2456957T3 (es) | 2014-04-24 |
| EP1941871A1 (en) | 2008-07-09 |
| HK1119950A1 (en) | 2009-03-20 |
| AU2003294973A1 (en) | 2004-10-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CHAD | Change of the owner's name or address (par. 44 patent law, par. patentforskriften) |
Owner name: BESINS HEALTHCARE LUXEMBOURG, LU |
|
| CHAD | Change of the owner's name or address (par. 44 patent law, par. patentforskriften) |
Owner name: BENSINS HEALTHCARE LUXEMBOURG SARL, LU |
|
| CHAD | Change of the owner's name or address (par. 44 patent law, par. patentforskriften) |
Owner name: BESINS HEALTHCARE LUXEMBOURG SARL, LU |
|
| MK1K | Patent expired |