NO333544B1 - Farmasoytisk vaginalsammensetning til reduksjon eller lindring av uterin dysrytmi samt anvendelse derav - Google Patents

Farmasoytisk vaginalsammensetning til reduksjon eller lindring av uterin dysrytmi samt anvendelse derav Download PDF

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Publication number
NO333544B1
NO333544B1 NO20042208A NO20042208A NO333544B1 NO 333544 B1 NO333544 B1 NO 333544B1 NO 20042208 A NO20042208 A NO 20042208A NO 20042208 A NO20042208 A NO 20042208A NO 333544 B1 NO333544 B1 NO 333544B1
Authority
NO
Norway
Prior art keywords
composition
agent
lidocaine
treating agent
concentration
Prior art date
Application number
NO20042208A
Other languages
English (en)
Norwegian (no)
Other versions
NO20042208L (no
Inventor
Howard L Levine
William J Bologna
Dominique De Ziegler
Original Assignee
Columbia Lab Bermuda Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Columbia Lab Bermuda Ltd filed Critical Columbia Lab Bermuda Ltd
Publication of NO20042208L publication Critical patent/NO20042208L/no
Publication of NO333544B1 publication Critical patent/NO333544B1/no

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245Amino benzoic acid types, e.g. procaine, novocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Pregnancy & Childbirth (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO20042208A 2001-10-29 2004-05-28 Farmasoytisk vaginalsammensetning til reduksjon eller lindring av uterin dysrytmi samt anvendelse derav NO333544B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33068401P 2001-10-29 2001-10-29
US10/278,912 US20030114394A1 (en) 2001-10-29 2002-10-24 Vaginally administered anti-dysrhythmic agents for treating pelvic pain
PCT/EP2002/012042 WO2003037381A1 (fr) 2001-10-29 2002-10-28 Agents antidysrythmiques administres par voie vaginale utilises pour traiter les douleurs pelviennes et la sterilite

Publications (2)

Publication Number Publication Date
NO20042208L NO20042208L (no) 2004-07-29
NO333544B1 true NO333544B1 (no) 2013-07-08

Family

ID=26959337

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20042208A NO333544B1 (no) 2001-10-29 2004-05-28 Farmasoytisk vaginalsammensetning til reduksjon eller lindring av uterin dysrytmi samt anvendelse derav

Country Status (34)

Country Link
US (1) US20030114394A1 (fr)
EP (2) EP1441770B1 (fr)
JP (2) JP2005511564A (fr)
KR (2) KR20100088718A (fr)
CN (1) CN100404072C (fr)
AR (1) AR037048A1 (fr)
AT (2) ATE451123T1 (fr)
AU (1) AU2002350644B2 (fr)
BR (1) BR0213585A (fr)
CA (1) CA2465132C (fr)
CY (2) CY1106000T1 (fr)
DE (2) DE60216495T2 (fr)
DK (2) DK1441770T3 (fr)
ES (2) ES2275928T3 (fr)
GE (1) GEP20094614B (fr)
HK (2) HK1063293A1 (fr)
HR (1) HRP20040479B1 (fr)
HU (1) HUP0402389A3 (fr)
IL (3) IL161513A0 (fr)
MA (1) MA26230A1 (fr)
ME (1) ME00255B (fr)
MX (1) MXPA04003976A (fr)
MY (2) MY149482A (fr)
NO (1) NO333544B1 (fr)
NZ (1) NZ532295A (fr)
PE (1) PE20030692A1 (fr)
PL (2) PL402549A1 (fr)
PT (2) PT1764111E (fr)
RS (1) RS51414B (fr)
RU (2) RU2476212C2 (fr)
SI (2) SI1441770T1 (fr)
UA (1) UA90077C2 (fr)
WO (1) WO2003037381A1 (fr)
ZA (1) ZA200402944B (fr)

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JP6654057B2 (ja) * 2016-02-10 2020-02-26 国立大学法人 筑波大学 局所麻酔薬を含有するポリイオンコンプレックスを有効成分とする局所疼痛制御用組成物
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Also Published As

Publication number Publication date
JP2011201909A (ja) 2011-10-13
DK1441770T3 (da) 2007-03-19
MXPA04003976A (es) 2004-07-08
JP2005511564A (ja) 2005-04-28
KR20100088718A (ko) 2010-08-10
MY145215A (en) 2012-01-13
NZ532295A (en) 2006-12-22
GEP20094614B (en) 2009-02-25
ATE346614T1 (de) 2006-12-15
RU2008133235A (ru) 2010-02-20
HK1102221A1 (en) 2007-11-09
DK1764111T3 (da) 2010-04-06
RS51414B (en) 2011-02-28
SI1441770T1 (sl) 2007-02-28
PT1764111E (pt) 2010-01-29
RS36704A (en) 2006-10-27
CN1578675A (zh) 2005-02-09
DE60216495D1 (de) 2007-01-11
AU2002350644B2 (en) 2008-05-08
PT1441770E (pt) 2007-01-31
DE60216495T2 (de) 2007-07-26
ES2336238T3 (es) 2010-04-09
EP1764111B1 (fr) 2009-12-09
MA26230A1 (fr) 2004-07-01
CA2465132A1 (fr) 2003-05-08
ATE451123T1 (de) 2009-12-15
WO2003037381A1 (fr) 2003-05-08
CA2465132C (fr) 2012-04-24
UA90077C2 (uk) 2010-04-12
CY1106000T1 (el) 2011-04-06
SI1764111T1 (sl) 2010-04-30
AR037048A1 (es) 2004-10-20
PL402549A1 (pl) 2013-08-05
MEP34908A (en) 2011-02-10
IL161513A (en) 2011-12-29
HUP0402389A3 (en) 2012-09-28
IL161513A0 (en) 2004-09-27
HK1063293A1 (en) 2004-12-24
MY149482A (en) 2013-08-30
HRP20040479A2 (en) 2004-10-31
HUP0402389A2 (hu) 2005-03-29
RU2004116346A (ru) 2005-03-10
EP1441770A1 (fr) 2004-08-04
EP1764111A1 (fr) 2007-03-21
ES2275928T3 (es) 2007-06-16
US20030114394A1 (en) 2003-06-19
CN100404072C (zh) 2008-07-23
IL211288A0 (en) 2011-04-28
RU2345758C2 (ru) 2009-02-10
ME00255B (fr) 2011-05-10
HRP20040479B1 (en) 2009-02-28
PE20030692A1 (es) 2003-08-28
IL211288A (en) 2014-02-27
RU2476212C2 (ru) 2013-02-27
PL369790A1 (en) 2005-05-02
CY1110288T1 (el) 2015-01-14
DE60234725D1 (de) 2010-01-21
EP1441770B1 (fr) 2006-11-29
NO20042208L (no) 2004-07-29
ZA200402944B (en) 2005-03-30
KR20050040820A (ko) 2005-05-03
BR0213585A (pt) 2004-08-24

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