NO332136B1 - Immunomodulerende heterosyklisk forbindelse, anvendelse derav for fremstilling av et medikament, og farmasoytisk eller veterinaermedisinsk preparat omfattende forbindelsen - Google Patents
Immunomodulerende heterosyklisk forbindelse, anvendelse derav for fremstilling av et medikament, og farmasoytisk eller veterinaermedisinsk preparat omfattende forbindelsen Download PDFInfo
- Publication number
- NO332136B1 NO332136B1 NO20054710A NO20054710A NO332136B1 NO 332136 B1 NO332136 B1 NO 332136B1 NO 20054710 A NO20054710 A NO 20054710A NO 20054710 A NO20054710 A NO 20054710A NO 332136 B1 NO332136 B1 NO 332136B1
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- Norway
- Prior art keywords
- ring
- alkyl
- compound according
- radical
- substituted
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
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- Transplantation (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0305876A GB0305876D0 (en) | 2003-03-14 | 2003-03-14 | Immuno inhibitory heterocyclic compounds |
| GB0319429A GB0319429D0 (en) | 2003-08-19 | 2003-08-19 | Immuno Inhibitory Heterocyclic compounds |
| PCT/GB2004/001008 WO2004081011A1 (en) | 2003-03-14 | 2004-03-10 | Immunomodulating heterocyclic compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20054710D0 NO20054710D0 (no) | 2005-10-13 |
| NO20054710L NO20054710L (no) | 2005-12-13 |
| NO332136B1 true NO332136B1 (no) | 2012-07-02 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20054710A NO332136B1 (no) | 2003-03-14 | 2005-10-13 | Immunomodulerende heterosyklisk forbindelse, anvendelse derav for fremstilling av et medikament, og farmasoytisk eller veterinaermedisinsk preparat omfattende forbindelsen |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US7276505B2 (de) |
| EP (2) | EP2284172A1 (de) |
| JP (1) | JP4892338B2 (de) |
| KR (1) | KR101133959B1 (de) |
| AT (1) | ATE489388T1 (de) |
| BR (1) | BRPI0408365B8 (de) |
| CA (1) | CA2519063C (de) |
| DE (1) | DE602004030225D1 (de) |
| DK (1) | DK1603917T3 (de) |
| EA (2) | EA009680B1 (de) |
| EC (1) | ECSP056104A (de) |
| HK (1) | HK1090921A1 (de) |
| IL (1) | IL170389A (de) |
| MX (1) | MXPA05009667A (de) |
| NO (1) | NO332136B1 (de) |
| NZ (1) | NZ541973A (de) |
| PL (2) | PL383655A1 (de) |
| PT (1) | PT1603917E (de) |
| SI (1) | SI1603917T1 (de) |
| WO (1) | WO2004081011A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA009680B1 (ru) * | 2003-03-14 | 2008-02-28 | Эвидекс Лимитед | Иммуномодулирующие гетероциклические соединения |
| GB0325644D0 (en) | 2003-11-04 | 2003-12-10 | Avidex Ltd | Immuno ihibitory pyrazolone compounds |
| GB0411770D0 (en) | 2004-05-26 | 2004-06-30 | Avidex Ltd | Immuno inhibitory heterocyclic compouds |
| JP4763697B2 (ja) * | 2004-08-09 | 2011-08-31 | メディジーン リミテッド | Ｃｄ８０抑制剤としての免疫調整性オキソピラゾロシンノリン類 |
| CA2618888A1 (en) * | 2005-08-10 | 2007-02-15 | Bayer Schering Pharma Aktiengesellschaft | Acyltryptophanols for fertility control |
| GB0603522D0 (en) * | 2006-02-22 | 2006-04-05 | Avidex Ltd | Kinase inhibition |
| CA2645731A1 (en) | 2006-03-15 | 2007-09-27 | Wyeth | N-substituted-azacyclylamines as histamine-3 antagonists |
| PE20080371A1 (es) | 2006-05-19 | 2008-04-09 | Wyeth Corp | N-benzoil-y-n-bencilpirrolidin-3-ilaminas como antagonistas de histamina-3 |
| US20100093867A1 (en) * | 2006-07-05 | 2010-04-15 | Ryoichi Matsuda | Method Of Treating Genetic Disease Caused By Nonsense Mutation |
| PE20081152A1 (es) | 2006-10-06 | 2008-08-10 | Wyeth Corp | Azaciclilaminas n-sustituidas como antagonistas de histamina-3 |
| PE20090812A1 (es) | 2007-07-16 | 2009-06-14 | Wyeth Corp | Derivados de aminoalquilazol como antagonistas de histamina-3 |
| EP2020404A1 (de) * | 2007-08-01 | 2009-02-04 | Bayer Schering Pharma Aktiengesellschaft | Cyanomethyl-substituierte N-Acyl-Tryptamine |
| JP5362729B2 (ja) | 2007-10-04 | 2013-12-11 | エフ．ホフマン−ラ ロシュ アーゲー | シクロプロピルアリールアミド誘導体及びその使用 |
| GB201021104D0 (en) * | 2010-12-13 | 2011-01-26 | Univ Leuven Kath | Novel compounds for the treatment of neurodegenerative diseases |
| EP2676666A1 (de) | 2012-06-20 | 2013-12-25 | Eidgenössische Technische Hochschule Zürich (ETH) | Verbindungen zur Verwendung bei der Diagnose oder Therapie anfälliger atherosklerotischer Plaques |
| EP2883883A1 (de) | 2013-12-16 | 2015-06-17 | Cardio3 Biosciences S.A. | Therapeutische Ziele und Mittel zur Behandlung von ischämiebedingten Reperfusionsschäden |
| EP3193609A4 (de) * | 2014-09-10 | 2018-02-28 | Epizyme, Inc. | Substituierte pyrrolidin-carboxamid-verbindungen |
| US11046683B2 (en) | 2016-12-15 | 2021-06-29 | Ono Pharmaceutical Co., Ltd. | Activator of TREK (TWIK RElated K+ channels) channels |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB629412A (en) | 1946-12-24 | 1949-09-20 | Geigy Ag J R | Manufacture of metallisable monoazo dyestuffs of the pyrazolone series |
| US3576637A (en) * | 1967-04-20 | 1971-04-27 | Konishiroku Photo Ind | Lith-type of emulsion containing pyrozolone |
| JPS61161285A (ja) * | 1984-12-28 | 1986-07-21 | ルセル−ユクラフ | ピラゾロ〔４，３−ｃ〕シンノリン−３−オンの誘導体、それらの塩類、これらの製造法、薬剤としての使用、これらを含有する組成物及び中間体生成物 |
| US4591589A (en) * | 1985-01-16 | 1986-05-27 | Roussel Uclaf | 2-aryl pyrazolo[4,3-c]cinnolin-3-ones |
| DE3626221A1 (de) | 1986-08-02 | 1988-02-04 | Agfa Gevaert Ag | Farbfotografisches aufzeichnungsmaterial zur herstellung farbiger aufsichtsbilder |
| US4906644A (en) | 1986-11-20 | 1990-03-06 | Mitsubishi Kasei Corporation | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor |
| DE3903993A1 (de) * | 1989-02-10 | 1990-08-16 | Basf Ag | Diarylsubstituierte heterocyclische verbindungen, ihre herstellung und arzneimittel daraus |
| AR006520A1 (es) * | 1996-03-20 | 1999-09-08 | Astra Pharma Prod | Derivados de 2-arilpirazolisoquinolina y cinolinona y procedimiento para su preparacion. |
| GB9713707D0 (en) * | 1997-06-27 | 1997-09-03 | Merck Sharp & Dohme | Therapeutic agents |
| SE0102404D0 (sv) * | 2001-07-04 | 2001-07-04 | Active Biotech Ab | Novel immunomodulating compounds |
| US7208495B2 (en) | 2001-07-05 | 2007-04-24 | Takeda Pharmaceutical Company Limited | Benzo-fused 5-membered hetrocycle compounds, process for preparation of the same, and use thereof |
| US7566711B2 (en) * | 2001-10-12 | 2009-07-28 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| US7081456B2 (en) | 2002-11-22 | 2006-07-25 | Active Biotech Ab | Immunomodulatory compounds |
| WO2004055014A1 (en) | 2002-12-16 | 2004-07-01 | Active Biotech Ab | Tetracyclic immunomodulatory compounds |
| EA009680B1 (ru) | 2003-03-14 | 2008-02-28 | Эвидекс Лимитед | Иммуномодулирующие гетероциклические соединения |
| GB0325644D0 (en) * | 2003-11-04 | 2003-12-10 | Avidex Ltd | Immuno ihibitory pyrazolone compounds |
| GB0411770D0 (en) * | 2004-05-26 | 2004-06-30 | Avidex Ltd | Immuno inhibitory heterocyclic compouds |
| JP4763697B2 (ja) * | 2004-08-09 | 2011-08-31 | メディジーン リミテッド | Ｃｄ８０抑制剤としての免疫調整性オキソピラゾロシンノリン類 |
| US20060221590A1 (en) * | 2005-03-31 | 2006-10-05 | Edoardo Campini | System and method for Advanced Mezzanine Card connection |
| GB0603522D0 (en) * | 2006-02-22 | 2006-04-05 | Avidex Ltd | Kinase inhibition |
-
2004
- 2004-03-10 EA EA200501370A patent/EA009680B1/ru not_active IP Right Cessation
- 2004-03-10 PT PT04719006T patent/PT1603917E/pt unknown
- 2004-03-10 DK DK04719006.1T patent/DK1603917T3/da active
- 2004-03-10 SI SI200431606T patent/SI1603917T1/sl unknown
- 2004-03-10 EP EP10014524A patent/EP2284172A1/de not_active Withdrawn
- 2004-03-10 EP EP04719006A patent/EP1603917B1/de not_active Expired - Lifetime
- 2004-03-10 DE DE602004030225T patent/DE602004030225D1/de not_active Expired - Lifetime
- 2004-03-10 KR KR1020057017070A patent/KR101133959B1/ko active IP Right Grant
- 2004-03-10 US US10/547,448 patent/US7276505B2/en not_active Expired - Lifetime
- 2004-03-10 BR BRPI0408365A patent/BRPI0408365B8/pt active IP Right Grant
- 2004-03-10 PL PL383655A patent/PL383655A1/pl unknown
- 2004-03-10 CA CA2519063A patent/CA2519063C/en not_active Expired - Lifetime
- 2004-03-10 NZ NZ541973A patent/NZ541973A/en not_active IP Right Cessation
- 2004-03-10 WO PCT/GB2004/001008 patent/WO2004081011A1/en active Application Filing
- 2004-03-10 JP JP2006505937A patent/JP4892338B2/ja not_active Expired - Lifetime
- 2004-03-10 EA EA200702435A patent/EA014080B1/ru not_active IP Right Cessation
- 2004-03-10 MX MXPA05009667A patent/MXPA05009667A/es active IP Right Grant
- 2004-03-10 AT AT04719006T patent/ATE489388T1/de active
- 2004-03-10 PL PL04719006T patent/PL1603917T3/pl unknown
-
2005
- 2005-08-18 IL IL170389A patent/IL170389A/en active IP Right Grant
- 2005-10-13 NO NO20054710A patent/NO332136B1/no unknown
- 2005-10-14 EC EC2005006104A patent/ECSP056104A/es unknown
-
2006
- 2006-10-19 HK HK06111573A patent/HK1090921A1/xx not_active IP Right Cessation
-
2007
- 2007-08-28 US US11/845,837 patent/US7598247B2/en not_active Expired - Lifetime
-
2009
- 2009-08-24 US US12/545,902 patent/US8309552B2/en active Active
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