NO323532B1 - Fremgangsmate for identifisering av kjemoterapeutiske midler ved bruk av transkripsjonsfaktor DP-1 - Google Patents

Fremgangsmate for identifisering av kjemoterapeutiske midler ved bruk av transkripsjonsfaktor DP-1 Download PDF

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Publication number
NO323532B1
NO323532B1 NO19951641A NO951641A NO323532B1 NO 323532 B1 NO323532 B1 NO 323532B1 NO 19951641 A NO19951641 A NO 19951641A NO 951641 A NO951641 A NO 951641A NO 323532 B1 NO323532 B1 NO 323532B1
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Norway
Prior art keywords
protein
dna
binding
complex
drtf1
Prior art date
Application number
NO19951641A
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English (en)
Norwegian (no)
Other versions
NO951641D0 (no
NO951641L (no
Inventor
Nicholas Barrie La Thangue
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Prolifix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929222715A external-priority patent/GB9222715D0/en
Priority claimed from GB939316206A external-priority patent/GB9316206D0/en
Application filed by Prolifix Ltd filed Critical Prolifix Ltd
Publication of NO951641D0 publication Critical patent/NO951641D0/no
Publication of NO951641L publication Critical patent/NO951641L/no
Publication of NO323532B1 publication Critical patent/NO323532B1/no

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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
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    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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    • C07K14/4738Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
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    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
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    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value

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  • General Health & Medical Sciences (AREA)
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  • Biotechnology (AREA)
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  • Urology & Nephrology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
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  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
NO19951641A 1992-10-29 1995-04-28 Fremgangsmate for identifisering av kjemoterapeutiske midler ved bruk av transkripsjonsfaktor DP-1 NO323532B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB929222715A GB9222715D0 (en) 1992-10-29 1992-10-29 Transcription factor
GB939316206A GB9316206D0 (en) 1993-08-05 1993-08-05 Transcription factor
PCT/GB1993/002227 WO1994010307A1 (en) 1992-10-29 1993-10-29 Transcription factor dp-1

Publications (3)

Publication Number Publication Date
NO951641D0 NO951641D0 (no) 1995-04-28
NO951641L NO951641L (no) 1995-06-29
NO323532B1 true NO323532B1 (no) 2007-06-04

Family

ID=26301878

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19951641A NO323532B1 (no) 1992-10-29 1995-04-28 Fremgangsmate for identifisering av kjemoterapeutiske midler ved bruk av transkripsjonsfaktor DP-1

Country Status (12)

Country Link
US (2) US5863757A (ja)
EP (2) EP0905236A1 (ja)
JP (1) JP3633616B2 (ja)
KR (1) KR950704484A (ja)
AT (1) ATE181360T1 (ja)
AU (1) AU675678B2 (ja)
CA (1) CA2148258A1 (ja)
DE (1) DE69325383T2 (ja)
DK (1) DK0669976T3 (ja)
NO (1) NO323532B1 (ja)
NZ (1) NZ257181A (ja)
WO (1) WO1994010307A1 (ja)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1350514A3 (en) * 1993-10-29 2004-07-07 The Brigham And Women's Hospital, Inc. Therapeutic use of cis-element decoys in vivo
GB9413327D0 (en) * 1994-07-01 1994-08-24 Medical Res Council Assay for inhibitors of dp-1
WO1996015243A1 (en) * 1994-11-15 1996-05-23 Prolifix Limited Transcription factor e2f-4
US6303335B1 (en) 1994-11-15 2001-10-16 Prolifix Limited Transcription factor E2F-4
GB9502873D0 (en) * 1995-02-14 1995-04-05 Medical Res Council Transcription factor
US5705350A (en) * 1995-08-29 1998-01-06 Duke University Transcription factor complexes in senescent cells
GB9608143D0 (en) * 1996-04-19 1996-06-26 Ver Nl Kanker Inst Assay
US6159691A (en) * 1996-05-15 2000-12-12 Prolifix Limited Assay for a putative regulator of cell cycle progression
GB9610195D0 (en) * 1996-05-15 1996-07-24 Medical Res Council Assay
FR2750705B1 (fr) * 1996-07-04 1998-10-30 Centre Nat Rech Scient Systeme de detection des interactions proteine-proteine
US6713449B1 (en) * 1996-09-30 2004-03-30 Kyowa Hakko Kogyo Co., Ltd. E2F activity inhibitory compounds
US6387649B1 (en) 1996-09-30 2002-05-14 Prolifix Limited Assay for a regulator of cell cycle progression
GB9626589D0 (en) * 1996-12-20 1997-02-05 Prolifix Ltd Peptides
US5932425A (en) * 1997-02-18 1999-08-03 Signal Pharmaceuticals, Inc. Compositions and methods for modulating cellular NF-κB activation
AU9550198A (en) 1997-10-21 1999-05-10 University Court Of The University Of Glasgow, The Jmy, a co-activator for p300/cbp, nucleic acid encoding jmy and uses thereof
WO1999053075A2 (en) * 1998-04-09 1999-10-21 E.I. Du Pont De Nemours And Company Cell cycle regulatory proteins cdc-16, dp-1, dp-2 and e2f from plants
AU6976300A (en) * 1999-09-16 2001-04-17 Mcgill University Methods for modulating cell proliferation
EP1214436A2 (en) * 1999-09-24 2002-06-19 Consejo Superior De Investigaciones Cientificas Wheat dp proteins and uses thereof
GB9923306D0 (en) 1999-10-01 1999-12-08 Isis Innovation Diagnostic and therapeutic epitope, and transgenic plant
US20030225012A1 (en) * 2002-05-31 2003-12-04 Isis Pharmaceuticals Inc. Antisense modulation of transcription factor DP-1 expression
GB0212885D0 (en) 2002-06-05 2002-07-17 Isis Innovation Therapeutic epitopes and uses thereof
EP1755639B1 (en) 2004-04-28 2017-08-16 BTG International Limited Epitopes related to coeliac disease
US10105437B2 (en) 2004-04-28 2018-10-23 Btg International Limited Epitopes related to coeliac disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993015227A1 (en) * 1992-01-29 1993-08-05 Duke University Method of assaying for the oncogenic state of cells

Also Published As

Publication number Publication date
WO1994010307A1 (en) 1994-05-11
EP0905236A1 (en) 1999-03-31
DE69325383D1 (de) 1999-07-22
DK0669976T3 (da) 2000-01-10
EP0669976A1 (en) 1995-09-06
JPH08503128A (ja) 1996-04-09
NO951641D0 (no) 1995-04-28
EP0669976B1 (en) 1999-06-16
JP3633616B2 (ja) 2005-03-30
NO951641L (no) 1995-06-29
KR950704484A (ko) 1995-11-20
US6150116A (en) 2000-11-21
AU5343994A (en) 1994-05-24
CA2148258A1 (en) 1994-05-11
ATE181360T1 (de) 1999-07-15
NZ257181A (en) 1997-07-27
DE69325383T2 (de) 1999-11-25
AU675678B2 (en) 1997-02-13
US5863757A (en) 1999-01-26

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