NO321511B1 - Sammensetning for rekonformering av multi-epitopiske antigener for a initiere en immunrespons og anvendelse av sammensetningen til fremstilling av et legemiddel - Google Patents
Sammensetning for rekonformering av multi-epitopiske antigener for a initiere en immunrespons og anvendelse av sammensetningen til fremstilling av et legemiddel Download PDFInfo
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- NO321511B1 NO321511B1 NO19985304A NO985304A NO321511B1 NO 321511 B1 NO321511 B1 NO 321511B1 NO 19985304 A NO19985304 A NO 19985304A NO 985304 A NO985304 A NO 985304A NO 321511 B1 NO321511 B1 NO 321511B1
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- C07K16/4258—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- Proteomics, Peptides & Aminoacids (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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Applications Claiming Priority (1)
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| PCT/IB1996/000461 WO1997042973A1 (en) | 1996-05-15 | 1996-05-15 | Method and composition for reconforming multi-epitopic antigens to initiate an immune response |
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| NO20061203A NO20061203L (no) | 1996-05-15 | 2006-03-15 | Fremgangsmate og sammensetning for rekontormering av multiepitopiske antigener for a initiere en immunrespons |
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| JP (1) | JP3565351B2 (de) |
| KR (1) | KR20020011137A (de) |
| AT (1) | ATE233102T1 (de) |
| BR (1) | BR9612619A (de) |
| CA (1) | CA2253602A1 (de) |
| DE (1) | DE69626423T2 (de) |
| DK (1) | DK0910407T3 (de) |
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| IL (1) | IL126803A (de) |
| NO (2) | NO321511B1 (de) |
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| PT (1) | PT910407E (de) |
| SI (1) | SI0910407T1 (de) |
| WO (1) | WO1997042973A1 (de) |
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| DK85193D0 (da) | 1993-07-16 | 1993-07-16 | Cancerforskningsfondet Af 1989 | Suppression of inhibitors |
| US20060159688A1 (en) * | 1996-05-15 | 2006-07-20 | Ragupathy Madiyalakan | Method for diagnosing efficacy of xenotypic antibody therapy |
| EP1297846A1 (de) * | 1996-05-15 | 2003-04-02 | Altarex Corporation | Verfahren und Zusammensetzung zur Rekonformierung multi-epitopischer Antigenen zur Induktion einer Immunantwort |
| US7318921B2 (en) * | 1996-05-15 | 2008-01-15 | Altarex Medical Corp. | Therapeutic compositions that alter the immune response |
| US20080220012A1 (en) * | 1996-05-15 | 2008-09-11 | Ragupathy Madiyalakan | Therapeutic Compositions that alter the immune response |
| US8038994B2 (en) | 1996-05-15 | 2011-10-18 | Quest Pharmatech Inc. | Combination therapy for treating disease |
| AU762699B2 (en) * | 1998-06-15 | 2003-07-03 | Oncoquest Inc. | Therapeutic compositions that produce an immune response by altering the antigen |
| JP2003519096A (ja) * | 1999-08-18 | 2003-06-17 | アルタレックス コーポレーション | Ｍｕｃ−１抗原に対する治療用抗体およびその使用方法 |
| US6716966B1 (en) | 1999-08-18 | 2004-04-06 | Altarex Corp. | Therapeutic binding agents against MUC-1 antigen and methods for their use |
| AU2002335932B2 (en) * | 2001-03-21 | 2007-11-01 | Altarex Medical Corp. | Therapeutic compositions that alter the immune response |
| GB2413960A (en) * | 2001-03-21 | 2005-11-16 | Altarex Inc | Treating ovarian cancer |
| CN100405062C (zh) * | 2001-04-10 | 2008-07-23 | 利兰·斯坦福青年大学托管委员会 | 抗体特异性分布的治疗和诊断使用 |
| GB2397018B (en) * | 2001-10-26 | 2006-05-31 | Altarex Medical Corp | Combination therapy for treating disease |
| WO2003086041A2 (en) * | 2002-04-11 | 2003-10-23 | Altarex Medical Corporation | Binding agents and their use in targeting tumor cells |
| US8025873B2 (en) * | 2002-06-20 | 2011-09-27 | Paladin Labs, Inc. | Chimeric antigens for eliciting an immune response |
| US8029803B2 (en) | 2002-06-20 | 2011-10-04 | Paladin Labs, Inc. | Chimeric antigens for eliciting an immune response |
| RS20050300A (en) | 2002-10-16 | 2007-08-03 | Euro-Celtique S.A., | Antibodies that bind cell-associated ca 125/0772p and methods of use thereof |
| EP1578445A4 (de) * | 2002-10-17 | 2007-04-04 | Altarex Medical Corp | Therapeutisches adjuvans |
| US8007805B2 (en) * | 2003-08-08 | 2011-08-30 | Paladin Labs, Inc. | Chimeric antigens for breaking host tolerance to foreign antigens |
| WO2006099175A2 (en) * | 2005-03-11 | 2006-09-21 | Euro-Celtique S.A. | Compositions comprising an anti-ca125 antibody and a cytotoxic compound and their use for the treatment of cancer |
| US8652836B2 (en) * | 2005-07-29 | 2014-02-18 | Providence Health System | Defective ribosomal products in blebs (DRibbles) and methods of use to stimulate an immune response |
| ZA200804078B (en) * | 2005-10-13 | 2009-09-30 | Virexx Medical Corp | Chimeric hepatitis C virus antigens for eliciting an immune response |
| JP2007320969A (ja) * | 2007-09-10 | 2007-12-13 | Altarex Medical Corp | 免疫応答を惹起するための、多数エピトープ含有抗原の再構成法および組成物 |
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| US4997762A (en) | 1984-01-31 | 1991-03-05 | Akzo N.V. | Tumor associated monocoloal antibodies derived from human B-cell line |
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| US5084396A (en) * | 1986-06-20 | 1992-01-28 | Neorx Corporation | Enhanced production of antibodies utilizing insolubilized immune complexes |
| US5009888A (en) | 1987-04-13 | 1991-04-23 | Genzyme Corporation | Therapeutic enzyme-antibody complexes |
| US4921790A (en) * | 1987-04-24 | 1990-05-01 | Research Corporation | Tumor specific assay for CA125 ovarian cancer antigen |
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| ATE235514T1 (de) * | 1994-12-28 | 2003-04-15 | Univ Kentucky | Monoklonaler anti-idiotypischer antikörper 3h1 aus maus |
| US5807978A (en) * | 1995-06-07 | 1998-09-15 | Kokolus; William J. | Immunogenic peptides of prostate specific antigen |
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| US7318921B2 (en) * | 1996-05-15 | 2008-01-15 | Altarex Medical Corp. | Therapeutic compositions that alter the immune response |
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| JPH1092532A (ja) * | 1996-09-17 | 1998-04-10 | Fujitsu Takamizawa Component Kk | コネクタとｉｃカードコネクタ |
| US6140091A (en) * | 1997-06-20 | 2000-10-31 | Boston Biomedical Research Institute | Anti-idiotype vaccines to elicit catalytic antibodies |
| US6052319A (en) * | 1997-12-04 | 2000-04-18 | Cypress Semiconductor Corp. | Apparatus and method for controlling experimental inventory |
| KR100271642B1 (ko) * | 1998-01-17 | 2000-11-15 | 김영환 | 다수의 문턱전압을 가지는 메모리 셀을 센싱 하는 회로 및 방법 |
| JP3670839B2 (ja) * | 1998-05-18 | 2005-07-13 | オリンパス株式会社 | 共焦点顕微鏡 |
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- 1996-05-15 ES ES96913660T patent/ES2193240T3/es not_active Expired - Lifetime
- 1996-05-15 US US08/913,290 patent/US6241985B1/en not_active Expired - Lifetime
- 1996-05-15 JP JP54068197A patent/JP3565351B2/ja not_active Expired - Fee Related
- 1996-05-15 DE DE69626423T patent/DE69626423T2/de not_active Expired - Lifetime
- 1996-05-15 HU HU9903770A patent/HUP9903770A3/hu unknown
- 1996-05-15 PT PT96913660T patent/PT910407E/pt unknown
- 1996-05-15 NZ NZ332588A patent/NZ332588A/xx not_active IP Right Cessation
- 1996-05-15 WO PCT/IB1996/000461 patent/WO1997042973A1/en active IP Right Grant
- 1996-05-15 BR BR9612619A patent/BR9612619A/pt not_active IP Right Cessation
- 1996-05-15 EP EP96913660A patent/EP0910407B1/de not_active Expired - Lifetime
- 1996-05-15 KR KR1020017015189A patent/KR20020011137A/ko not_active Application Discontinuation
- 1996-05-15 DK DK96913660T patent/DK0910407T3/da active
- 1996-05-15 AT AT96913660T patent/ATE233102T1/de not_active IP Right Cessation
- 1996-05-15 NZ NZ516264A patent/NZ516264A/en not_active IP Right Cessation
- 1996-05-15 SI SI9630604T patent/SI0910407T1/xx unknown
- 1996-05-15 CA CA002253602A patent/CA2253602A1/en not_active Abandoned
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1997
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1998
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- 1998-11-13 NO NO19985304A patent/NO321511B1/no not_active IP Right Cessation
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2001
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2006
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- 2006-06-21 US US11/472,808 patent/US20070036798A1/en not_active Abandoned
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2007
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- 2007-10-31 US US11/981,644 patent/US20080206318A1/en not_active Abandoned
- 2007-10-31 US US11/981,714 patent/US20080131443A1/en not_active Abandoned
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