NO321455B1 - Anvendelse av en forbindelse som inhiberer bindingen av faktor AP1 til sekvens SEQ ID Nr. 1 til fremstilling av et medikament til behandling av og/eller forebygging av neurodegenerative lidelser. - Google Patents
Anvendelse av en forbindelse som inhiberer bindingen av faktor AP1 til sekvens SEQ ID Nr. 1 til fremstilling av et medikament til behandling av og/eller forebygging av neurodegenerative lidelser. Download PDFInfo
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- NO321455B1 NO321455B1 NO19954888A NO954888A NO321455B1 NO 321455 B1 NO321455 B1 NO 321455B1 NO 19954888 A NO19954888 A NO 19954888A NO 954888 A NO954888 A NO 954888A NO 321455 B1 NO321455 B1 NO 321455B1
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- 239000012581 transferrin Substances 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/13—Decoys
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9307962A FR2707880B1 (fr) | 1993-06-30 | 1993-06-30 | Compositions pharmaceutiques et leur utilisation, notamment pour le traitement des maladies neurodégénératives. |
| PCT/FR1994/000771 WO1995001429A1 (fr) | 1993-06-30 | 1994-06-27 | Compositions pharmaceutiques et leur utilisation, notamment pour le traitement des maladies neurodegeneratives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO954888L NO954888L (no) | 1995-12-01 |
| NO954888D0 NO954888D0 (no) | 1995-12-01 |
| NO321455B1 true NO321455B1 (no) | 2006-05-15 |
Family
ID=9448720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19954888A NO321455B1 (no) | 1993-06-30 | 1995-12-01 | Anvendelse av en forbindelse som inhiberer bindingen av faktor AP1 til sekvens SEQ ID Nr. 1 til fremstilling av et medikament til behandling av og/eller forebygging av neurodegenerative lidelser. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6140112A (de) |
| EP (2) | EP0707644B1 (de) |
| JP (1) | JP3755825B2 (de) |
| KR (1) | KR100517879B1 (de) |
| AT (1) | ATE276360T1 (de) |
| AU (1) | AU696644B2 (de) |
| CA (1) | CA2166318C (de) |
| DE (1) | DE69433996T2 (de) |
| DK (1) | DK0707644T3 (de) |
| ES (1) | ES2227528T3 (de) |
| FI (1) | FI120942B (de) |
| FR (1) | FR2707880B1 (de) |
| NO (1) | NO321455B1 (de) |
| PT (1) | PT707644E (de) |
| WO (1) | WO1995001429A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6017903A (en) | 1996-09-27 | 2000-01-25 | Guilford Pharmaceuticals Inc. | Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors |
| US5824662A (en) | 1996-09-27 | 1998-10-20 | Guilford Pharmaceuticals Inc. | Treatment of global and focal ischemia using naaladase inhibitors |
| KR20000036227A (ko) | 1996-09-27 | 2000-06-26 | 토마스 씨. 서 | 날라다아제조성물, 글루탐산염 이상 치료법 및 동물내의 뉴우런활성법 |
| US6599741B1 (en) | 1999-09-14 | 2003-07-29 | Avontec Gmbh | Modulating transcription of genes in vascular cells |
| CN1315402A (zh) * | 2000-03-28 | 2001-10-03 | 上海博德基因开发有限公司 | 一种新的多肽——人淀粉类前体蛋白结合蛋白14和编码这种多肽的多核苷酸 |
| CN1315439A (zh) * | 2000-03-29 | 2001-10-03 | 上海博德基因开发有限公司 | 一种新的多肽——人淀粉类前体蛋白结合蛋白9和编码这种多肽的多核苷酸 |
| DE10308045B3 (de) | 2003-02-26 | 2004-06-17 | Lurgi Ag | Verfahren und Vorrichtung zur kontinuierlichen Gewinnung freier Weinsäure aus Kaliumhydrogentartrat enthaltenden Rohstoffen |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2573436B1 (fr) * | 1984-11-20 | 1989-02-17 | Pasteur Institut | Adn recombinant comportant une sequence nucleotidique codant pour un polypeptide determine sous le controle d'un promoteur d'adenovirus, vecteurs contenant cet adn recombinant, cellules eucaryotes transformees par cet adn recombinant, produits d'excretion de ces cellules transformees et leurs applications, notamment a la constitution de vaccins |
| WO1991011535A1 (en) * | 1990-01-30 | 1991-08-08 | Childrens Hospital Of Los Angeles | Inhibition of transcription by double-stranded oligonucleotides |
| AU7906691A (en) * | 1990-05-23 | 1991-12-10 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | Adeno-associated virus (aav)-based eucaryotic vectors |
| FR2675803B1 (fr) * | 1991-04-25 | 1996-09-06 | Genset Sa | Oligonucleotides fermes, antisens et sens et leurs applications. |
| GB9114437D0 (en) * | 1991-07-03 | 1991-08-21 | Health Lab Service Board | Recombinant adenoviruses and the use thereof for detecting the presence in eukaryotic cells of the expression products of specific genes |
| FR2708283B1 (fr) * | 1994-01-14 | 1995-10-20 | Rhone Poulenc Rorer Sa | Compositions pharmaceutiques et leur utilisation, notamment pour le traitement des maladies neurodégénératives. |
-
1993
- 1993-06-30 FR FR9307962A patent/FR2707880B1/fr not_active Expired - Lifetime
-
1994
- 1994-06-27 ES ES94920987T patent/ES2227528T3/es not_active Expired - Lifetime
- 1994-06-27 US US08/569,149 patent/US6140112A/en not_active Expired - Lifetime
- 1994-06-27 JP JP50330895A patent/JP3755825B2/ja not_active Expired - Lifetime
- 1994-06-27 WO PCT/FR1994/000771 patent/WO1995001429A1/fr active IP Right Grant
- 1994-06-27 DE DE69433996T patent/DE69433996T2/de not_active Expired - Lifetime
- 1994-06-27 CA CA002166318A patent/CA2166318C/fr not_active Expired - Lifetime
- 1994-06-27 DK DK94920987T patent/DK0707644T3/da active
- 1994-06-27 EP EP94920987A patent/EP0707644B1/de not_active Expired - Lifetime
- 1994-06-27 KR KR1019950706050A patent/KR100517879B1/ko not_active IP Right Cessation
- 1994-06-27 AT AT94920987T patent/ATE276360T1/de active
- 1994-06-27 AU AU71882/94A patent/AU696644B2/en not_active Expired
- 1994-06-27 EP EP04006618A patent/EP1454984A1/de not_active Withdrawn
- 1994-06-27 PT PT94920987T patent/PT707644E/pt unknown
-
1995
- 1995-12-01 NO NO19954888A patent/NO321455B1/no not_active IP Right Cessation
- 1995-12-29 FI FI956353A patent/FI120942B/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1454984A1 (de) | 2004-09-08 |
| DK0707644T3 (da) | 2005-01-17 |
| AU7188294A (en) | 1995-01-24 |
| FR2707880A1 (fr) | 1995-01-27 |
| CA2166318C (fr) | 2009-02-10 |
| KR960703432A (ko) | 1996-08-17 |
| DE69433996T2 (de) | 2005-09-22 |
| JP3755825B2 (ja) | 2006-03-15 |
| JPH08512043A (ja) | 1996-12-17 |
| EP0707644B1 (de) | 2004-09-15 |
| DE69433996D1 (de) | 2004-10-21 |
| WO1995001429A1 (fr) | 1995-01-12 |
| AU696644B2 (en) | 1998-09-17 |
| CA2166318A1 (fr) | 1995-01-12 |
| ES2227528T3 (es) | 2005-04-01 |
| FI120942B (fi) | 2010-05-14 |
| FI956353A0 (fi) | 1995-12-29 |
| FR2707880B1 (fr) | 1995-10-06 |
| NO954888L (no) | 1995-12-01 |
| ATE276360T1 (de) | 2004-10-15 |
| KR100517879B1 (ko) | 2005-12-16 |
| EP0707644A1 (de) | 1996-04-24 |
| US6140112A (en) | 2000-10-31 |
| NO954888D0 (no) | 1995-12-01 |
| FI956353A (fi) | 1995-12-29 |
| PT707644E (pt) | 2005-01-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |