NO319885B1 - Fremgangsmate for fremstilling av rekombinante, adenoassosierte viruser (AAV), og deres anvendelse. - Google Patents
Fremgangsmate for fremstilling av rekombinante, adenoassosierte viruser (AAV), og deres anvendelse. Download PDFInfo
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- NO319885B1 NO319885B1 NO19962950A NO962950A NO319885B1 NO 319885 B1 NO319885 B1 NO 319885B1 NO 19962950 A NO19962950 A NO 19962950A NO 962950 A NO962950 A NO 962950A NO 319885 B1 NO319885 B1 NO 319885B1
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- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14151—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9400934A FR2716682B1 (fr) | 1994-01-28 | 1994-01-28 | Procédé de préparation de virus adéno-associés (AAV) recombinants et utilisations. |
| PCT/FR1995/000054 WO1995020671A1 (fr) | 1994-01-28 | 1995-01-18 | Procede de preparation de virus adeno-associes (aav) recombinants et utilisations |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO962950L NO962950L (no) | 1996-07-12 |
| NO962950D0 NO962950D0 (no) | 1996-07-12 |
| NO319885B1 true NO319885B1 (no) | 2005-09-26 |
Family
ID=9459501
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19962950A NO319885B1 (no) | 1994-01-28 | 1996-07-12 | Fremgangsmate for fremstilling av rekombinante, adenoassosierte viruser (AAV), og deres anvendelse. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5789390A (es) |
| EP (1) | EP0741793B1 (es) |
| JP (1) | JP3810078B2 (es) |
| KR (1) | KR100403708B1 (es) |
| AT (1) | ATE310097T1 (es) |
| AU (1) | AU706647B2 (es) |
| CA (1) | CA2181602A1 (es) |
| DE (1) | DE69534618T2 (es) |
| DK (1) | DK0741793T3 (es) |
| ES (1) | ES2252738T3 (es) |
| FI (1) | FI962990A (es) |
| FR (1) | FR2716682B1 (es) |
| IL (1) | IL112461A0 (es) |
| MX (1) | MX9603002A (es) |
| NO (1) | NO319885B1 (es) |
| WO (1) | WO1995020671A1 (es) |
| ZA (1) | ZA95628B (es) |
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| US20020159979A1 (en) | 1994-06-06 | 2002-10-31 | Children's Hospital, Inc. | Adeno-associated virus materials and methods |
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| US5856152A (en) * | 1994-10-28 | 1999-01-05 | The Trustees Of The University Of Pennsylvania | Hybrid adenovirus-AAV vector and methods of use therefor |
| FR2738575B1 (fr) * | 1995-09-08 | 1997-10-10 | Centre Nat Rech Scient | Cellules pour la production d'adenovirus recombinants |
| IL116816A (en) * | 1995-01-20 | 2003-05-29 | Rhone Poulenc Rorer Sa | Cell for the production of a defective recombinant adenovirus or an adeno-associated virus and the various uses thereof |
| US5756283A (en) * | 1995-06-05 | 1998-05-26 | The Trustees Of The University Of Pennsylvania | Method for improved production of recombinant adeno-associated viruses for gene therapy |
| US6281010B1 (en) * | 1995-06-05 | 2001-08-28 | The Trustees Of The University Of Pennsylvania | Adenovirus gene therapy vehicle and cell line |
| FR2735789B1 (fr) * | 1995-06-23 | 1997-07-25 | Centre Nat Rech Scient | Adenovirus recombinants, leur utilisation pour preparer des aav, lignee cellulaire complementaire et compositions pharmaceutiques les contenant |
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| US6162796A (en) * | 1995-09-27 | 2000-12-19 | The Rockefeller University | Method for transferring genes to the heart using AAV vectors |
| US20030027250A1 (en) * | 1995-12-15 | 2003-02-06 | Mitchell Lloyd G. | Methods and compositions for use in spliceosome mediated RNA trans-splicing |
| US20060088938A1 (en) * | 1995-12-15 | 2006-04-27 | Mitchell Lloyd G | Methods and compositions for use in spliceosome mediated RNA trans-splicing in plants |
| US5846528A (en) | 1996-01-18 | 1998-12-08 | Avigen, Inc. | Treating anemia using recombinant adeno-associated virus virions comprising an EPO DNA sequence |
| US5858351A (en) * | 1996-01-18 | 1999-01-12 | Avigen, Inc. | Methods for delivering DNA to muscle cells using recombinant adeno-associated virus vectors |
| US5962313A (en) * | 1996-01-18 | 1999-10-05 | Avigen, Inc. | Adeno-associated virus vectors comprising a gene encoding a lyosomal enzyme |
| US20020037867A1 (en) * | 1999-02-26 | 2002-03-28 | James M. Wilson | Method for recombinant adeno-associated virus-directed gene therapy |
| US5866552A (en) * | 1996-09-06 | 1999-02-02 | The Trustees Of The University Of Pennsylvania | Method for expressing a gene in the absence of an immune response |
| EP0928202A4 (en) * | 1996-09-25 | 2001-09-05 | Cell Genesys Inc | NON-INVASIVE ADMINISTRATION OF ADENO-ASSOCIATED VIRAL VECTORS |
| EP0950091A2 (en) * | 1996-12-18 | 1999-10-20 | Targeted Genetics Corporation | Aav split-packaging genes and cell lines comprising such genes for use in the production of recombinant aav vectors |
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| US20040161409A1 (en) * | 1997-07-25 | 2004-08-19 | Kurtzman Gary J. | Induction of immune response to antigens expressed by recombinant adeno-associated virus |
| US20030125278A1 (en) * | 1997-08-13 | 2003-07-03 | Tang De-Chu C. | Immunization of animals by topical applications of a salmonella-based vector |
| US6716823B1 (en) | 1997-08-13 | 2004-04-06 | The Uab Research Foundation | Noninvasive genetic immunization, expression products therefrom, and uses thereof |
| US20030045492A1 (en) * | 1997-08-13 | 2003-03-06 | Tang De-Chu C. | Vaccination by topical application of recombinant vectors |
| US6706693B1 (en) | 1997-08-13 | 2004-03-16 | The Uab Research Foundation | Vaccination by topical application of genetic vectors |
| US6348450B1 (en) * | 1997-08-13 | 2002-02-19 | The Uab Research Foundation | Noninvasive genetic immunization, expression products therefrom and uses thereof |
| US6251677B1 (en) | 1997-08-25 | 2001-06-26 | The Trustees Of The University Of Pennsylvania | Hybrid adenovirus-AAV virus and methods of use thereof |
| US6642051B1 (en) | 1997-10-21 | 2003-11-04 | Targeted Genetics Corporation | Amplifiable adeno-associated virus(AAV) packaging cassettes for the production of recombinant AAV vectors |
| CA2309810C (en) * | 1997-12-03 | 2014-07-08 | Roche Diagnostics Gmbh | Erythropoietin with high specific activity |
| DE19830141A1 (de) * | 1998-07-06 | 2000-01-13 | Regine Heilbronn | Rekombinante Herpesviren für die Erzeugung rekombinanter Adeno-Assoziierter-Viren |
| US6303362B1 (en) | 1998-11-19 | 2001-10-16 | The Board Of Trustees Of The Leland Stanford Junior University | Adenoviral vector and methods for making and using the same |
| US6759050B1 (en) | 1998-12-03 | 2004-07-06 | Avigen, Inc. | Excipients for use in adeno-associated virus pharmaceutical formulations, and pharmaceutical formulations made therewith |
| US6387368B1 (en) | 1999-02-08 | 2002-05-14 | The Trustees Of The University Of Pennsylvania | Hybrid adenovirus-AAV virus and methods of use thereof |
| DE19905501B4 (de) | 1999-02-10 | 2005-05-19 | MediGene AG, Gesellschaft für molekularbiologische Kardiologie und Onkologie | Verfahren zur Herstellung eines rekombinanten Adeno-assoziierten Virus, geeignete Mittel hierzu sowie Verwendung zur Herstellung eines Arzneimittels |
| US20040043488A1 (en) * | 1999-02-17 | 2004-03-04 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Adeno-associated viral gene-transfer vector system |
| US6893865B1 (en) | 1999-04-28 | 2005-05-17 | Targeted Genetics Corporation | Methods, compositions, and cells for encapsidating recombinant vectors in AAV particles |
| US20040009936A1 (en) * | 1999-05-03 | 2004-01-15 | Tang De-Chu C. | Vaccine and drug delivery by topical application of vectors and vector extracts |
| AU3274401A (en) | 2000-01-05 | 2001-07-16 | Fred Hutchinson Cancer Research Center | Compositions and methods for efficient aav vector production |
| AU3988401A (en) * | 2000-02-25 | 2001-09-03 | Ludwig Inst Cancer Res | Materials and methods involving hybrid vascular endothelial growth factor dnas and proteins |
| EP1415160A2 (en) * | 2000-09-30 | 2004-05-06 | Diversa Corporation | Whole cell engineering by mutagenizing a substantial portion of a starting genome, combining mutations, and optionally repeating |
| US6916635B2 (en) * | 2000-10-02 | 2005-07-12 | The Research Foundation Of State University Of New York | Hybrid adenovirus/adeno-associated virus vectors and methods of use thereof |
| US20040126774A1 (en) * | 2001-01-08 | 2004-07-01 | Mitchell Lioyd G. | Correction of factor VIII genetic defects using spliceosome mediated RNA trans splicing |
| WO2002082904A2 (en) | 2001-04-13 | 2002-10-24 | The Trustees Of The University Of Pennsylvania | Method of treating or retarding the development of blindness |
| EP1427816A4 (en) | 2001-09-18 | 2004-12-01 | Clontech Lab Inc | METHOD FOR PRODUCING ADENOVIRAL VECTORS BASED ON A SITE SPECIFIC RECOMBINASE |
| US7399753B2 (en) * | 2002-02-25 | 2008-07-15 | Virxsys Corporation | Trans-splicing mediated photodynamic therapy |
| JP2005536231A (ja) * | 2002-05-08 | 2005-12-02 | イントロン，インコーポレーテッド | アデノウイルスに細胞選択的複製をもたらすための、スプライセオソーム媒介型ｒｎａトランススプライシングの使用 |
| WO2007068784A1 (en) | 2005-12-14 | 2007-06-21 | Licentia Ltd | Novel neurotrophic factor protein and uses thereof |
| WO2004038380A2 (en) * | 2002-10-23 | 2004-05-06 | Intronn, Inc. | Screening methods for identification of efficient pre-trans-splicing molecules |
| TW200518669A (en) * | 2003-09-12 | 2005-06-16 | Vertex Pharma | Animal model for protease activity and liver damage |
| US7968334B2 (en) * | 2004-01-23 | 2011-06-28 | Virxsys Corporation | Expression of apoAI and variants thereof using spliceosome mediated RNA trans-splicing |
| EP1716165A4 (en) * | 2004-01-23 | 2008-06-18 | Virxsys Corp | EXPRESSION OF APOLIPROTEIN A1 (APOA-1) AND VARIANTS USING SPLICE COMPLEX-INDUCED RNA TRANSPLANT |
| WO2005070948A1 (en) * | 2004-01-23 | 2005-08-04 | Intronn, Inc. | Correction of alpha-1-antitrypsin genetic defects using spliceosome mediated rna trans splicing |
| US20070207461A1 (en) * | 2004-02-23 | 2007-09-06 | Crucell Holland B.V. | Virus Purification Methods |
| EP1732947B1 (en) * | 2004-03-05 | 2011-04-27 | Vegenics Pty Ltd | Growth factor binding constructs materials and methods |
| US7582442B2 (en) | 2004-03-16 | 2009-09-01 | The Regents Of The University Of Michigan | Methods and compositions for using aleveolar macrophage phospholipase A2 |
| US7319015B2 (en) * | 2004-03-16 | 2008-01-15 | The Regents Of The University Of Michigan | Methods and compositions for using alveolar macrophage phospholipase A2 |
| AU2005287393A1 (en) * | 2004-06-18 | 2006-03-30 | The University Of Montana | AAV mediated gene delivery to cochlear cells |
| WO2006014798A2 (en) * | 2004-07-27 | 2006-02-09 | Mount Sinai School Of Medicine | Methods and compositions for using sax2 |
| US20060094110A1 (en) * | 2004-07-30 | 2006-05-04 | Mcgarrity Gerard J | Use of spliceosome mediated RNA trans-splicing for immunotherapy |
| US20060134658A1 (en) * | 2004-08-09 | 2006-06-22 | Garcia-Blanco Mariano A | Use of RNA trans-splicing for generation of interfering RNA molecules |
| FI20050753A (fi) | 2004-09-03 | 2006-03-04 | Licentia Oy | Uudet peptidit |
| DE102004047492B4 (de) * | 2004-09-23 | 2006-07-20 | Jost-Werke Gmbh & Co. Kg | Verfahren zum Übertragen von elektrischer, pneumatischer oder hydraulischer Energie sowie ein Energieübertragungssystem |
| US7871795B2 (en) | 2004-10-08 | 2011-01-18 | Virxsys Corporation | Targeted trans-splicing of highly abundant transcripts for in vivo production of recombinant proteins |
| EP1831365B1 (en) * | 2004-10-08 | 2013-08-07 | VIRxSYS Corporation | Use of rna trans-splicing for antibody gene transfer and antibody polypeptide production |
| US7531523B2 (en) * | 2005-02-17 | 2009-05-12 | Vertex Pharmaceuticals Incorporated | Sodium channel protein type III alpha-subunit splice variant |
| EP1863511A2 (en) * | 2005-02-23 | 2007-12-12 | UAB Research Foundation | Alkyl-glycoside enhanced vaccination |
| US8574595B2 (en) * | 2005-04-11 | 2013-11-05 | Crucell Holland B.V. | Virus purification using ultrafiltration |
| AU2006279462A1 (en) | 2005-08-15 | 2007-02-22 | Vegenics Limited | Modified VEGF and PDGF with improved angiogenic properties |
| US20080200408A1 (en) * | 2005-09-30 | 2008-08-21 | Mccormack Kenneth | Deletion mutants of tetrodotoxin-resistant sodium channel alpha subunit |
| US7972813B2 (en) * | 2005-09-30 | 2011-07-05 | Vertex Pharmaceuticals Incorporated | Tetrodotoxin-resistant sodium channel alpha subunit |
| US20090214496A1 (en) * | 2006-01-30 | 2009-08-27 | Licentia Ltd. | Bmx/etk tyrosine kinase gene therapy materials and methods |
| EP2018184B1 (en) | 2006-05-17 | 2013-09-11 | The Ludwig Institute for Cancer Research | Anti-VEGF-B antibody for the treatment or prophylaxis of diabetes type II or metabolic syndrome |
| FI20070808A0 (fi) | 2007-10-25 | 2007-10-25 | Mart Saarma | GDNF:n silmukointivariantit ja niiden käytöt |
| US20090196854A1 (en) * | 2008-02-04 | 2009-08-06 | Kytos Biosystems S.A. | Methods and compositions for use of crl 5803 cells for expression of biotherapeutics and encapsulated cell-based delivery |
| FI20080326A0 (fi) | 2008-04-30 | 2008-04-30 | Licentia Oy | Neurotroofinen tekijä MANF ja sen käytöt |
| JP2011526916A (ja) | 2008-06-30 | 2011-10-20 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 全身性紅斑性狼瘡を同定および処置するための診断標的および治療標的としてのリソソームホスホリパーゼａ２（ｌｐｌａ２）活性 |
| CA2840175C (en) | 2011-05-19 | 2021-11-16 | The Regents Of The University Of Michigan | Integrin alpha-2 binding agents and use thereof to inhibit cancer cell proliferation |
| WO2013079687A1 (en) | 2011-11-30 | 2013-06-06 | The Chancellor, Masters And Scholars Of The University Of Oxford | Inkt cell modulators and methods of using the same |
| GB201120860D0 (en) | 2011-12-05 | 2012-01-18 | Cambridge Entpr Ltd | Cancer immunotherapy |
| WO2013184209A1 (en) | 2012-06-04 | 2013-12-12 | Ludwig Institute For Cancer Research Ltd. | Mif for use in methods of treating subjects with a neurodegenerative disorder |
| CA2884245C (en) | 2012-09-06 | 2023-03-14 | The University Of Chicago | Antisense polynucleotides to induce exon skipping and methods of treating dystrophies |
| PT2956476T (pt) | 2013-02-18 | 2020-02-21 | Vegenics Pty Ltd | Moléculas de ligação e usos destas |
| WO2014191630A2 (en) | 2013-05-28 | 2014-12-04 | Helsingin Yliopisto | Non-human animal model encoding a non-functional manf gene |
| DK3283500T3 (en) | 2015-04-08 | 2020-11-16 | Univ Chicago | Compositions and methods for correcting limb girdle muscular dystrophy type 2C using exon skipping |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5139941A (en) * | 1985-10-31 | 1992-08-18 | University Of Florida Research Foundation, Inc. | AAV transduction vectors |
| AU7906691A (en) * | 1990-05-23 | 1991-12-10 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | Adeno-associated virus (aav)-based eucaryotic vectors |
| US5173414A (en) * | 1990-10-30 | 1992-12-22 | Applied Immune Sciences, Inc. | Production of recombinant adeno-associated virus vectors |
-
1994
- 1994-01-28 FR FR9400934A patent/FR2716682B1/fr not_active Expired - Fee Related
-
1995
- 1995-01-18 MX MX9603002A patent/MX9603002A/es not_active IP Right Cessation
- 1995-01-18 EP EP95907045A patent/EP0741793B1/fr not_active Expired - Lifetime
- 1995-01-18 DK DK95907045T patent/DK0741793T3/da active
- 1995-01-18 ES ES95907045T patent/ES2252738T3/es not_active Expired - Lifetime
- 1995-01-18 AT AT95907045T patent/ATE310097T1/de not_active IP Right Cessation
- 1995-01-18 KR KR1019960704129A patent/KR100403708B1/ko not_active IP Right Cessation
- 1995-01-18 WO PCT/FR1995/000054 patent/WO1995020671A1/fr active IP Right Grant
- 1995-01-18 AU AU15395/95A patent/AU706647B2/en not_active Ceased
- 1995-01-18 DE DE69534618T patent/DE69534618T2/de not_active Expired - Fee Related
- 1995-01-18 JP JP51990995A patent/JP3810078B2/ja not_active Expired - Fee Related
- 1995-01-18 US US08/682,520 patent/US5789390A/en not_active Expired - Fee Related
- 1995-01-18 CA CA002181602A patent/CA2181602A1/fr not_active Abandoned
- 1995-01-26 ZA ZA95628A patent/ZA95628B/xx unknown
- 1995-01-26 IL IL11246195A patent/IL112461A0/xx active IP Right Grant
-
1996
- 1996-07-12 NO NO19962950A patent/NO319885B1/no unknown
- 1996-07-26 FI FI962990A patent/FI962990A/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2716682A1 (fr) | 1995-09-01 |
| CA2181602A1 (fr) | 1995-08-03 |
| FI962990A0 (fi) | 1996-07-26 |
| DE69534618T2 (de) | 2006-07-27 |
| ZA95628B (en) | 1995-10-23 |
| DK0741793T3 (da) | 2006-03-27 |
| KR100403708B1 (ko) | 2004-05-31 |
| FR2716682B1 (fr) | 1996-04-26 |
| IL112461A0 (en) | 1995-03-30 |
| EP0741793B1 (fr) | 2005-11-16 |
| WO1995020671A1 (fr) | 1995-08-03 |
| JPH09509051A (ja) | 1997-09-16 |
| ATE310097T1 (de) | 2005-12-15 |
| NO962950L (no) | 1996-07-12 |
| FI962990A (fi) | 1996-07-26 |
| MX9603002A (es) | 1997-06-28 |
| AU1539595A (en) | 1995-08-15 |
| AU706647B2 (en) | 1999-06-17 |
| ES2252738T3 (es) | 2006-05-16 |
| US5789390A (en) | 1998-08-04 |
| EP0741793A1 (fr) | 1996-11-13 |
| DE69534618D1 (de) | 2005-12-22 |
| NO962950D0 (no) | 1996-07-12 |
| JP3810078B2 (ja) | 2006-08-16 |
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