NO317131B1 - Blodbehandlingssystem som styres av tilsynelatende hematokritt - Google Patents
Blodbehandlingssystem som styres av tilsynelatende hematokritt Download PDFInfo
- Publication number
- NO317131B1 NO317131B1 NO19970538A NO970538A NO317131B1 NO 317131 B1 NO317131 B1 NO 317131B1 NO 19970538 A NO19970538 A NO 19970538A NO 970538 A NO970538 A NO 970538A NO 317131 B1 NO317131 B1 NO 317131B1
- Authority
- NO
- Norway
- Prior art keywords
- separation device
- whole blood
- value
- plasma
- platelet
- Prior art date
Links
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- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
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- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- External Artificial Organs (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Centrifugal Separators (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/473,316 US5730883A (en) | 1991-12-23 | 1995-06-07 | Blood processing systems and methods using apparent hematocrit as a process control parameter |
PCT/US1996/007714 WO1996040399A1 (en) | 1995-06-07 | 1996-05-22 | Blood processing systems controlled by apparent hematocrit |
Publications (3)
Publication Number | Publication Date |
---|---|
NO970538D0 NO970538D0 (no) | 1997-02-06 |
NO970538L NO970538L (no) | 1997-04-04 |
NO317131B1 true NO317131B1 (no) | 2004-08-23 |
Family
ID=23879065
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19970538A NO317131B1 (no) | 1995-06-07 | 1997-02-06 | Blodbehandlingssystem som styres av tilsynelatende hematokritt |
Country Status (9)
Country | Link |
---|---|
US (6) | US5730883A (de) |
EP (1) | EP0775005B1 (de) |
JP (1) | JP4085339B2 (de) |
AU (1) | AU700756B2 (de) |
CA (1) | CA2195067C (de) |
DE (1) | DE69632012T2 (de) |
ES (1) | ES2218593T3 (de) |
NO (1) | NO317131B1 (de) |
WO (1) | WO1996040399A1 (de) |
Families Citing this family (80)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5730883A (en) | 1991-12-23 | 1998-03-24 | Baxter International Inc. | Blood processing systems and methods using apparent hematocrit as a process control parameter |
US6632191B1 (en) * | 1994-10-13 | 2003-10-14 | Haemonetics Corporation | System and method for separating blood components |
US5581687A (en) * | 1994-11-10 | 1996-12-03 | Baxter International Inc. | Interactive control systems for medical processing devices |
US5958250A (en) | 1995-06-07 | 1999-09-28 | Baxter International Inc. | Blood processing systems and methods which optically derive the volume of platelets contained in a plasma constituent |
US6312607B1 (en) | 1995-06-07 | 2001-11-06 | Baxter International Inc. | Blood processing systems and methods which optically monitor incremental platelet volumes in a plasma constituent |
WO1998043720A1 (en) * | 1997-04-03 | 1998-10-08 | Baxter International Inc. | Interface detection and control systems and methods |
JP3944279B2 (ja) * | 1997-06-16 | 2007-07-11 | テルモ株式会社 | 血液成分採取装置 |
JP3817079B2 (ja) * | 1998-10-05 | 2006-08-30 | テルモ株式会社 | 血液成分採取装置 |
US6752777B1 (en) | 1997-06-16 | 2004-06-22 | Terumo Kabushiki Kaisha | Blood component collecting apparatus |
US6027441A (en) * | 1997-07-01 | 2000-02-22 | Baxter International Inc. | Systems and methods providing a liquid-primed, single flow access chamber |
IT1302015B1 (it) * | 1998-08-07 | 2000-07-20 | Dideco Spa | Sistema di controllo automatico di cella per la centrifugazione delsangue. |
JP3196838B2 (ja) * | 1998-09-11 | 2001-08-06 | ヘモネティクス・コーポレーション | アフェレーシス装置及び血液製剤の製造方法 |
US6180001B1 (en) * | 1998-11-24 | 2001-01-30 | Moco Thermal Industries, Incorporated | Apparatus for separating light and heavy phase liquids |
WO2000049401A1 (en) * | 1999-02-19 | 2000-08-24 | Deka Products Limited Partnership | Apparatus and method for performing hematocrit blood testing |
US6284142B1 (en) * | 1999-09-03 | 2001-09-04 | Baxter International Inc. | Sensing systems and methods for differentiating between different cellular blood species during extracorporeal blood separation or processing |
US6348156B1 (en) | 1999-09-03 | 2002-02-19 | Baxter International Inc. | Blood processing systems and methods with sensors to detect contamination due to presence of cellular components or dilution due to presence of plasma |
US6875191B2 (en) * | 1999-09-03 | 2005-04-05 | Baxter International Inc. | Blood processing systems and methods that alternate flow of blood component and additive solution through an in-line leukofilter |
US6294094B1 (en) * | 1999-09-03 | 2001-09-25 | Baxter International Inc. | Systems and methods for sensing red blood cell hematocrit |
US6524231B1 (en) * | 1999-09-03 | 2003-02-25 | Baxter International Inc. | Blood separation chamber with constricted interior channel and recessed passage |
US7011761B2 (en) * | 1999-09-03 | 2006-03-14 | Baxter International Inc. | Red blood cell processing systems and methods which control red blood cell hematocrit |
JP2003516175A (ja) * | 1999-10-16 | 2003-05-13 | バクスター・インターナショナル・インコーポレイテッド | 全血から赤血球、血小板および血漿を得るための自動収集システムおよび方法 |
US6730054B2 (en) * | 1999-10-16 | 2004-05-04 | Baxter International Inc. | Blood collection systems and methods that derive estimated effects upon the donor's blood volume and hematocrit |
US7430478B2 (en) | 2000-03-01 | 2008-09-30 | Caridian Bct, Inc. | Blood processing information system with blood loss equivalency tracking |
CA2672076A1 (en) * | 2000-03-01 | 2001-09-07 | Caridianbct, Inc. | Extracorporeal blood processing information management system |
JP3847053B2 (ja) * | 2000-03-15 | 2006-11-15 | 純 菊地 | 血液分析装置 |
JP4786812B2 (ja) * | 2001-03-29 | 2011-10-05 | テルモ株式会社 | 血液成分採取装置 |
WO2002087662A1 (en) * | 2001-04-27 | 2002-11-07 | Nexell Therapeutics Inc. | Cell processing and fluid transfer apparatus and method of use |
US20030040938A1 (en) * | 2001-04-28 | 2003-02-27 | Baxter International Inc. | A system and method for managing inventory of blood component collection soft goods in a blood component collection facility |
ITMI20010899A1 (it) * | 2001-04-30 | 2002-10-30 | Dideco Spa | Sistema di controllo della fase di lavaggio in cella per la centrifugazione del sangue |
FR2825261B1 (fr) * | 2001-06-01 | 2003-09-12 | Maco Pharma Sa | Ligne de prelevement du sang placentaire comprenant une poche de rincage |
US6890291B2 (en) * | 2001-06-25 | 2005-05-10 | Mission Medical, Inc. | Integrated automatic blood collection and processing unit |
US6878105B2 (en) * | 2001-08-16 | 2005-04-12 | Baxter International Inc. | Red blood cell processing systems and methods with deliberate under spill of red blood cells |
US7479123B2 (en) | 2002-03-04 | 2009-01-20 | Therakos, Inc. | Method for collecting a desired blood component and performing a photopheresis treatment |
US7186230B2 (en) * | 2002-03-04 | 2007-03-06 | Therakos, Inc | Method and apparatus for the continuous separation of biological fluids into components |
US7211037B2 (en) * | 2002-03-04 | 2007-05-01 | Therakos, Inc. | Apparatus for the continuous separation of biological fluids into components and method of using same |
EP1497645A2 (de) * | 2002-04-19 | 2005-01-19 | Mission Medical, Inc. | Integrierte automatische blutverarbeitungseinheit |
US7806845B2 (en) * | 2002-04-24 | 2010-10-05 | Biomet Biologics, Llc | Blood separation and concentration system |
US6982038B2 (en) * | 2002-06-14 | 2006-01-03 | Medtronic, Inc. | Centrifuge system utilizing disposable components and automated processing of blood to collect platelet rich plasma |
US7297272B2 (en) * | 2002-10-24 | 2007-11-20 | Fenwal, Inc. | Separation apparatus and method |
JP3958733B2 (ja) * | 2002-11-14 | 2007-08-15 | 日機装株式会社 | 血液浄化装置 |
US20050049539A1 (en) * | 2003-09-03 | 2005-03-03 | O'hara Gerald P. | Control system for driving fluids through an extracorporeal blood circuit |
US7704454B1 (en) * | 2003-10-08 | 2010-04-27 | Caridianbct, Inc. | Methods and devices for processing blood |
AU2004237844B2 (en) | 2003-12-23 | 2011-01-27 | Therakos, Inc. | Extracorporeal photopheresis in combination with anti-TNF treatment |
US7087177B2 (en) * | 2004-04-16 | 2006-08-08 | Baxter International Inc. | Methods for determining flow rates of biological fluids |
FR2878145B1 (fr) * | 2004-11-24 | 2007-01-05 | Maco Pharma Sa | Systeme a poches pour l'echantillonnage automatique d'un fluide biologique |
US7476209B2 (en) * | 2004-12-21 | 2009-01-13 | Therakos, Inc. | Method and apparatus for collecting a blood component and performing a photopheresis treatment |
US20060226086A1 (en) * | 2005-04-08 | 2006-10-12 | Robinson Thomas C | Centrifuge for blood processing systems |
US9169461B2 (en) * | 2005-11-02 | 2015-10-27 | Therakos, Inc. | Use of apoptotic cells ex vivo to generate regulatory T cells |
US8506825B2 (en) * | 2006-11-27 | 2013-08-13 | Sorin Group Italia S.R.L. | Method and apparatus for controlling the flow rate of washing solution during the washing step in a blood centrifugation bowl |
US8961448B2 (en) * | 2008-01-28 | 2015-02-24 | Peter Forsell | Implantable drainage device |
US8075468B2 (en) | 2008-02-27 | 2011-12-13 | Fenwal, Inc. | Systems and methods for mid-processing calculation of blood composition |
US8685258B2 (en) | 2008-02-27 | 2014-04-01 | Fenwal, Inc. | Systems and methods for conveying multiple blood components to a recipient |
US8702637B2 (en) | 2008-04-14 | 2014-04-22 | Haemonetics Corporation | System and method for optimized apheresis draw and return |
US8454548B2 (en) * | 2008-04-14 | 2013-06-04 | Haemonetics Corporation | System and method for plasma reduced platelet collection |
US8628489B2 (en) * | 2008-04-14 | 2014-01-14 | Haemonetics Corporation | Three-line apheresis system and method |
DE602008004637D1 (de) | 2008-06-10 | 2011-03-03 | Sorin Group Italia Srl | Sicherungsmechanismus, insbesondere für Bluttrennungszentrifugen und dergleichen |
US8834402B2 (en) | 2009-03-12 | 2014-09-16 | Haemonetics Corporation | System and method for the re-anticoagulation of platelet rich plasma |
US9603989B2 (en) * | 2010-08-24 | 2017-03-28 | Fenwal, Inc. | Methods for anticoagulating blood |
WO2012060848A1 (en) | 2010-11-05 | 2012-05-10 | Haemonetics Corporation | System and method for automated platelet wash |
US9302042B2 (en) | 2010-12-30 | 2016-04-05 | Haemonetics Corporation | System and method for collecting platelets and anticipating plasma return |
WO2012137086A1 (en) | 2011-04-08 | 2012-10-11 | Sorin Group Italia S.R.L. | Disposable device for centrifugal blood separation |
WO2012154572A1 (en) * | 2011-05-06 | 2012-11-15 | Haemonetics Corporation | System and method for automated separation of whole blood |
US11386993B2 (en) | 2011-05-18 | 2022-07-12 | Fenwal, Inc. | Plasma collection with remote programming |
US9393359B2 (en) | 2012-04-10 | 2016-07-19 | Fenwal, Inc. | Systems and methods for achieving target post-procedure fraction of cells remaining, hematocrit, and blood volume during a therapeutic red blood cell exchange procedure with optional isovolemic hemodilution |
US9733805B2 (en) | 2012-06-26 | 2017-08-15 | Terumo Bct, Inc. | Generating procedures for entering data prior to separating a liquid into components |
WO2014011499A1 (en) | 2012-07-12 | 2014-01-16 | Terumo Bct, Inc. | Hybrid blood component storage bag and method of making such bag |
AU2013337284B2 (en) | 2012-11-05 | 2018-03-08 | Haemonetics Corporation | Continuous flow separation chamber |
US10039876B2 (en) | 2014-04-30 | 2018-08-07 | Sorin Group Italia S.R.L. | System for removing undesirable elements from blood using a first wash step and a second wash step |
US9597444B2 (en) | 2014-05-12 | 2017-03-21 | Fenwal, Inc. | Systems and methods for determining replacement fluid and plasma flow rates for red blood cell exchange procedures |
US9833557B2 (en) | 2014-12-19 | 2017-12-05 | Fenwal, Inc. | Systems and methods for determining free plasma hemoglobin |
US10758652B2 (en) | 2017-05-30 | 2020-09-01 | Haemonetics Corporation | System and method for collecting plasma |
US10792416B2 (en) | 2017-05-30 | 2020-10-06 | Haemonetics Corporation | System and method for collecting plasma |
US11065376B2 (en) | 2018-03-26 | 2021-07-20 | Haemonetics Corporation | Plasmapheresis centrifuge bowl |
WO2019195414A1 (en) * | 2018-04-03 | 2019-10-10 | Fenwal, Inc. | Plasmapheresis methods |
US12033750B2 (en) | 2018-05-21 | 2024-07-09 | Fenwal, Inc. | Plasma collection |
US11412967B2 (en) | 2018-05-21 | 2022-08-16 | Fenwal, Inc. | Systems and methods for plasma collection |
CN112587740B (zh) | 2018-05-21 | 2024-08-02 | 汾沃有限公司 | 用于采集血浆的系统 |
CN111939599B (zh) * | 2020-07-14 | 2024-01-12 | 山东中保康医疗器具有限公司 | 富血小板血浆的制备方法及装置 |
WO2022159584A1 (en) * | 2021-01-25 | 2022-07-28 | Fenwal, Inc. | Systems and methods for generating ac volume recommendation for plasma collection |
US20230181808A1 (en) | 2021-12-09 | 2023-06-15 | Fenwal, Inc. | Systems And Methods For Setting A Continuous-Flow Centrifuge Rotation Rate |
Family Cites Families (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3916892A (en) * | 1974-04-29 | 1975-11-04 | Haemonetics Corp | Phlebotomy needle system incorporating means to add anticoagulant and wash liquid |
US4481827A (en) * | 1981-12-15 | 1984-11-13 | Baxter Travenol Laboratories, Inc. | Blood fractionation apparatus having collection rate display system |
US4458539A (en) * | 1981-12-15 | 1984-07-10 | Baxter Travenol Laboratories, Inc. | Blood fractionation apparatus having collected volume display system |
US4447191A (en) * | 1981-12-15 | 1984-05-08 | Baxter Travenol Laboratories, Inc. | Control circuit for a blood fractionation apparatus |
US4501531A (en) * | 1981-12-15 | 1985-02-26 | Baxter Travenol Laboratories, Inc. | Control circuit for a blood fractionation apparatus |
SE451946B (sv) * | 1982-12-10 | 1987-11-09 | Gambro Lundia Ab | Anordning for avlegsnande av en eller flera fraktioner ur helblod, plasma eller liknande kroppsvetskor |
US5034135A (en) * | 1982-12-13 | 1991-07-23 | William F. McLaughlin | Blood fractionation system and method |
US4537561A (en) * | 1983-02-24 | 1985-08-27 | Medical Technology, Ltd. | Peristaltic infusion pump and disposable cassette for use therewith |
US4540406A (en) * | 1983-05-02 | 1985-09-10 | Thoratec Laboratories Corporation | Anticoagulant delivery system for use with an auto-transfusion system |
FR2548541B1 (fr) * | 1983-07-07 | 1986-09-12 | Rhone Poulenc Sa | Procede de plasmapherese et appareillage utilisable notamment pour ce procede |
FR2548907B1 (fr) * | 1983-07-13 | 1985-11-08 | Rhone Poulenc Sa | Procede de plasmapherese et appareillage utilisable notamment pour ce procede |
DE3410286C2 (de) * | 1984-03-21 | 1986-01-23 | Fresenius AG, 6380 Bad Homburg | Verfahren zur Trennung von Blut sowie Vorrichtung zur Durchführung des Verfahrens |
JPH0657250B2 (ja) * | 1984-06-29 | 1994-08-03 | バクスター・インターナショナル・インコーポレーテッド | 血液抽出及び再注輸の血流制御装置 |
US4573961A (en) * | 1984-10-29 | 1986-03-04 | Extracorporeal Medical Specialties, Inc. | Electronic control methods for puvapheresis apparatus |
US4692138A (en) * | 1984-10-29 | 1987-09-08 | Mcneilab, Inc. | Pump block for interfacing irradiation chamber to photoactivation patient treatment system |
US4879040A (en) * | 1984-11-15 | 1989-11-07 | Baxter International Inc. | Adaptive filter concentrate flow control system and method |
US4713176A (en) * | 1985-04-12 | 1987-12-15 | Hemascience Laboratories, Inc. | Plasmapheresis system and method |
JPS6340532A (ja) * | 1986-04-05 | 1988-02-20 | 日本光電工業株式会社 | 血液成分の監視装置 |
DE3632176A1 (de) * | 1986-09-22 | 1988-04-07 | Fresenius Ag | Steuerung eines systems zur trennung der bestandteile des einem spender "in vivo" entnommenen blutes |
US4883462A (en) * | 1987-01-30 | 1989-11-28 | Baxter Travenol Laboratories, Inc. | Blood extraction assist apparatus and method |
US5370802A (en) * | 1987-01-30 | 1994-12-06 | Baxter International Inc. | Enhanced yield platelet collection systems and methods |
US4769001A (en) * | 1987-02-25 | 1988-09-06 | Baxter International Inc. | Method and apparatus for calibrating plural pump fluid flow system |
DE3720665A1 (de) * | 1987-06-23 | 1989-01-05 | Schael Wilfried | Vorrichtung zur haemodialyse und haemofiltration |
US4850995A (en) * | 1987-08-19 | 1989-07-25 | Cobe Laboratories, Inc. | Centrifugal separation of blood |
US4795314A (en) * | 1987-08-24 | 1989-01-03 | Cobe Laboratories, Inc. | Condition responsive pump control utilizing integrated, commanded, and sensed flowrate signals |
US4867738A (en) * | 1987-09-14 | 1989-09-19 | International Technidyne Corporation | Apparatus and methods for utilizing autotransfusion systems and related equipment |
US4850998A (en) * | 1987-10-07 | 1989-07-25 | Baxter International Inc. | Method for wetting a plasmapheresis filter with anticoagulant |
US5188588A (en) * | 1987-11-25 | 1993-02-23 | Baxter Internatonal Inc. | Single needle continuous hemapheresis apparatus and methods |
US4994188A (en) * | 1988-02-05 | 1991-02-19 | Baxter International Inc. | Adaptive filtrate flow control system using controlled reduction in filter efficiency |
DE3909967A1 (de) * | 1989-03-25 | 1990-09-27 | Fresenius Ag | Haemodialysegeraet mit automatischer einstellung des dialysierfluessigkeitsflusses |
US4995268A (en) * | 1989-09-01 | 1991-02-26 | Ash Medical System, Incorporated | Method and apparatus for determining a rate of flow of blood for an extracorporeal blood therapy instrument |
US5112298A (en) * | 1990-06-25 | 1992-05-12 | Baxter International Inc. | Apheresis method and device |
US5069792A (en) * | 1990-07-10 | 1991-12-03 | Baxter International Inc. | Adaptive filter flow control system and method |
US5234608A (en) * | 1990-12-11 | 1993-08-10 | Baxter International Inc. | Systems and methods for processing cellular rich suspensions |
FR2672219B1 (fr) * | 1991-02-06 | 1998-09-11 | Hospal Ind | Procede de commande de la circulation du sang dans un circuit a aiguille unique. |
DE4126341C1 (de) * | 1991-08-09 | 1993-01-28 | Fresenius Ag, 6380 Bad Homburg, De | |
DE4129639C1 (de) * | 1991-09-06 | 1993-02-11 | Fresenius Ag, 6380 Bad Homburg, De | |
US5437561A (en) | 1991-12-09 | 1995-08-01 | Aavid Engineering, Inc. | Self-locking tab |
US5549834A (en) * | 1991-12-23 | 1996-08-27 | Baxter International Inc. | Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes |
US5730883A (en) * | 1991-12-23 | 1998-03-24 | Baxter International Inc. | Blood processing systems and methods using apparent hematocrit as a process control parameter |
US5437624A (en) * | 1993-08-23 | 1995-08-01 | Cobe Laboratories, Inc. | Single needle recirculation system for harvesting blood components |
US6319471B1 (en) * | 1992-07-10 | 2001-11-20 | Gambro, Inc. | Apparatus for producing blood component products |
US5496265A (en) * | 1992-03-04 | 1996-03-05 | Cobe Laboratories, Inc. | Blood component collection system with optimizer |
US5421812A (en) * | 1992-03-04 | 1995-06-06 | Cobe Laboratories, Inc. | Method and apparatus for controlling concentrations in tubing system |
US5423738A (en) * | 1992-03-13 | 1995-06-13 | Robinson; Thomas C. | Blood pumping and processing system |
US5378227A (en) * | 1992-08-11 | 1995-01-03 | Cobe Laboratories, Inc. | Biological/pharmaceutical method and apparatus for collecting and mixing fluids |
DE69425966T2 (de) * | 1993-04-27 | 2001-03-29 | Haemonetics Corp., Braintree | Apheresisgerät |
US5427695A (en) * | 1993-07-26 | 1995-06-27 | Baxter International Inc. | Systems and methods for on line collecting and resuspending cellular-rich blood products like platelet concentrate |
US5437598A (en) * | 1994-01-21 | 1995-08-01 | Cobe Laboratories, Inc. | Automation of plasma sequestration |
US5704889A (en) * | 1995-04-14 | 1998-01-06 | Cobe Laboratories, Inc. | Spillover collection of sparse components such as mononuclear cells in a centrifuge apparatus |
-
1995
- 1995-06-07 US US08/473,316 patent/US5730883A/en not_active Expired - Fee Related
-
1996
- 1996-05-22 AU AU58776/96A patent/AU700756B2/en not_active Expired
- 1996-05-22 DE DE69632012T patent/DE69632012T2/de not_active Expired - Lifetime
- 1996-05-22 WO PCT/US1996/007714 patent/WO1996040399A1/en active IP Right Grant
- 1996-05-22 CA CA002195067A patent/CA2195067C/en not_active Expired - Lifetime
- 1996-05-22 JP JP50072497A patent/JP4085339B2/ja not_active Expired - Lifetime
- 1996-05-22 EP EP96920494A patent/EP0775005B1/de not_active Expired - Lifetime
- 1996-05-22 ES ES96920494T patent/ES2218593T3/es not_active Expired - Lifetime
-
1997
- 1997-02-06 NO NO19970538A patent/NO317131B1/no not_active IP Right Cessation
- 1997-10-30 US US08/960,674 patent/US6059979A/en not_active Expired - Lifetime
-
2000
- 2000-03-16 US US09/527,148 patent/US6207063B1/en not_active Expired - Fee Related
-
2001
- 2001-02-23 US US09/793,801 patent/US6451203B2/en not_active Expired - Lifetime
- 2001-03-02 US US09/797,176 patent/US20010008221A1/en active Pending
-
2002
- 2002-09-11 US US10/241,617 patent/US6802982B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5730883A (en) | 1998-03-24 |
EP0775005A1 (de) | 1997-05-28 |
US6059979A (en) | 2000-05-09 |
EP0775005A4 (de) | 1999-01-13 |
US6451203B2 (en) | 2002-09-17 |
DE69632012D1 (de) | 2004-05-06 |
JP4085339B2 (ja) | 2008-05-14 |
US20010008221A1 (en) | 2001-07-19 |
AU5877696A (en) | 1996-12-30 |
CA2195067C (en) | 2008-05-06 |
US6802982B2 (en) | 2004-10-12 |
ES2218593T3 (es) | 2004-11-16 |
CA2195067A1 (en) | 1996-12-19 |
JPH10504043A (ja) | 1998-04-14 |
DE69632012T2 (de) | 2004-12-30 |
EP0775005B1 (de) | 2004-03-31 |
NO970538L (no) | 1997-04-04 |
US6207063B1 (en) | 2001-03-27 |
US20010006810A1 (en) | 2001-07-05 |
WO1996040399A1 (en) | 1996-12-19 |
NO970538D0 (no) | 1997-02-06 |
AU700756B2 (en) | 1999-01-14 |
US20030062318A1 (en) | 2003-04-03 |
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