NO308580B1 - Anvendelse av kondenserte cykliske forbindelser for fremstilling av en antihypertriglyceridemisk medisin - Google Patents
Anvendelse av kondenserte cykliske forbindelser for fremstilling av en antihypertriglyceridemisk medisinInfo
- Publication number
- NO308580B1 NO308580B1 NO953961A NO953961A NO308580B1 NO 308580 B1 NO308580 B1 NO 308580B1 NO 953961 A NO953961 A NO 953961A NO 953961 A NO953961 A NO 953961A NO 308580 B1 NO308580 B1 NO 308580B1
- Authority
- NO
- Norway
- Prior art keywords
- hypertriglyceridemic
- drug
- preparation
- cyclic compounds
- condensed cyclic
- Prior art date
Links
- 230000001346 anti-hypertriglyceridemic effect Effects 0.000 title 1
- 150000001923 cyclic compounds Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24413694 | 1994-10-07 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO953961D0 NO953961D0 (no) | 1995-10-05 |
| NO953961L NO953961L (no) | 1996-04-09 |
| NO308580B1 true NO308580B1 (no) | 2000-10-02 |
Family
ID=17114301
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO953961A NO308580B1 (no) | 1994-10-07 | 1995-10-05 | Anvendelse av kondenserte cykliske forbindelser for fremstilling av en antihypertriglyceridemisk medisin |
Country Status (11)
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2231052C (en) * | 1995-09-13 | 2007-11-13 | Takeda Chemical Industries, Ltd. | Benzoxazepine compounds, their production and use as lipid lowering agents |
| EP0862562B1 (en) * | 1995-09-13 | 2001-07-04 | Takeda Chemical Industries, Ltd. | Benzoxazepine compounds, their production and use as lipid lowering agents |
| JPH10513202A (ja) * | 1996-06-11 | 1998-12-15 | ゾナジェン，インコーポレイテッド | キトサン薬物送達システム |
| CN1252795A (zh) | 1997-04-21 | 2000-05-10 | 武田药品工业株式会社 | 4,1－苯并氧氮杂、它们的类似物和它们作为抑生长素兴奋剂的用途 |
| JP4204657B2 (ja) * | 1997-12-05 | 2009-01-07 | 有限会社ケムフィズ | 糖尿病の予防・治療剤 |
| AU774929B2 (en) | 1998-03-31 | 2004-07-15 | Institutes For Pharmaceutical Discovery, Llc, The | Substituted indolealkanoic acids |
| US6207664B1 (en) | 1998-11-25 | 2001-03-27 | Pfizer Inc. | Squalene synthetase inhibitor agents |
| TNSN99224A1 (fr) * | 1998-12-01 | 2005-11-10 | Inst For Pharm Discovery Inc | Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique |
| CA2370141A1 (en) | 1999-05-26 | 2000-12-07 | James D. Rodgers | 1,4-benzodiazepin-2-ones useful as hiv reverse transcriptase inhibitors |
| MXPA02001340A (es) * | 1999-08-05 | 2004-07-16 | Prescient Neuropharma Inc | Compuestos novedosos 1,4-benzodiazepina y derivados de los mismos. |
| KR20030048465A (ko) * | 2000-11-09 | 2003-06-19 | 다케다 야쿠힌 고교 가부시키가이샤 | 고밀도 지질단백질-콜레스테롤 상승제 |
| KR20040100835A (ko) | 2001-02-15 | 2004-12-02 | 킹 파머슈티칼스 리서치 앤드 디벨로프먼트 아이엔씨 | 안정된 제약및 갑상선 내분비 호르몬 구성물 및 그제조방법 |
| US20030027786A1 (en) * | 2001-06-06 | 2003-02-06 | Karsten Maeder | Lipase inhibiting composition |
| WO2003002147A1 (fr) * | 2001-06-28 | 2003-01-09 | Takeda Chemical Industries, Ltd. | Medicaments destines a la prevention/au traitement de troubles fonctionnels des organes et du dysfonctionnement des organes |
| US7101569B2 (en) | 2001-08-14 | 2006-09-05 | Franz G Andrew | Methods of administering levothyroxine pharmaceutical compositions |
| EP1591120A4 (en) * | 2003-01-28 | 2009-06-10 | Takeda Chemical Industries Ltd | RECEPTOR AGONISTS |
| EP1689383B1 (en) | 2003-11-19 | 2012-10-31 | Metabasis Therapeutics, Inc. | Novel phosphorus-containing thyromimetics |
| MX2007001536A (es) * | 2004-08-09 | 2007-04-02 | Takeda Pharmaceutical | Agente para disminuir la proteina c reactiva. |
| US7790745B2 (en) | 2005-10-21 | 2010-09-07 | Bristol-Myers Squibb Company | Tetrahydroisoquinoline LXR Modulators |
| JP2009512715A (ja) | 2005-10-21 | 2009-03-26 | ノバルティス アクチエンゲゼルシャフト | レニン阻害剤と抗異脂肪血症剤および／または抗肥満症剤の組み合わせ |
| BRPI0811204A8 (pt) | 2007-05-10 | 2015-09-22 | Bristol Myers Squibb Co | Tetra-hidroibenzo-1,4-diazepinas substituídas por arila e heteroarila e uso das mesmas para bloquear a recaptação de norepinefrina, dopamina e serotonina |
| US20120046364A1 (en) | 2009-02-10 | 2012-02-23 | Metabasis Therapeutics, Inc. | Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use |
| US20130156720A1 (en) | 2010-08-27 | 2013-06-20 | Ironwood Pharmaceuticals, Inc. | Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders |
| KR102698413B1 (ko) | 2020-05-05 | 2024-08-26 | 뉴베일런트, 아이엔씨. | 헤테로방향족 거대환식 에터 화학치료제 |
| WO2021226208A2 (en) | 2020-05-05 | 2021-11-11 | Nuvalent, Inc. | Heteroaromatic macrocyclic ether chemotherapeutic agents |
| JP2024537795A (ja) | 2021-10-01 | 2024-10-16 | ヌバレント， インク． | ヘテロ芳香族大環状エーテル化合物の固体形態、薬学的組成物、及び調製 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5180717A (en) * | 1988-08-16 | 1993-01-19 | The Upjohn Company | Bivalent ligands effective for blocking ACAT enzyme for lowering plasma triglycerides and for elevating HDL cholesterol |
| FR2659332B1 (fr) * | 1990-03-08 | 1994-04-29 | Adit Et Cie | Nouvelles pyrrolo [1,2-a] thieno [3,2-f] diazepines [1,4], leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| DE69332792T2 (de) * | 1992-04-20 | 2004-01-15 | Takeda Chemical Industries Ltd | 4,1-Benzoxazepinderivate als Squalen-Synthetase Inhibitoren und ihre Verwendung zur Behandlung von Hypercholesterämie und als Fungizide |
| CA2099346A1 (en) * | 1992-07-17 | 1994-01-18 | Shinji Ohmori | Lipid metabolism improving composition |
| AU678503B2 (en) * | 1993-09-24 | 1997-05-29 | Takeda Chemical Industries Ltd. | Condensed heterocyclic compounds and their use as squalene synthetase inhibitors |
| WO1995021834A1 (en) * | 1994-02-09 | 1995-08-17 | Takeda Chemical Industries, Ltd. | Optically active 4,1-benzoxazepine derivatives useful as squalene synthase inhibitors |
-
1995
- 1995-09-21 TW TW084109892A patent/TW401301B/zh not_active IP Right Cessation
- 1995-09-26 EP EP95115109A patent/EP0705607A2/en not_active Withdrawn
- 1995-10-04 NZ NZ280165A patent/NZ280165A/en unknown
- 1995-10-05 HU HU9502918A patent/HUT73422A/hu unknown
- 1995-10-05 NO NO953961A patent/NO308580B1/no not_active IP Right Cessation
- 1995-10-05 AU AU33081/95A patent/AU703422B2/en not_active Ceased
- 1995-10-06 KR KR1019950034188A patent/KR960013370A/ko not_active Ceased
- 1995-10-06 CA CA002160092A patent/CA2160092A1/en not_active Abandoned
- 1995-10-06 CN CN95117761A patent/CN1128657A/zh active Pending
- 1995-10-06 FI FI954773A patent/FI954773A7/fi unknown
- 1995-10-06 RU RU95117068/14A patent/RU2166320C2/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| NZ280165A (en) | 1997-07-27 |
| FI954773A7 (fi) | 1996-04-08 |
| AU3308195A (en) | 1996-04-18 |
| KR960013370A (ko) | 1996-05-22 |
| NO953961L (no) | 1996-04-09 |
| RU2166320C2 (ru) | 2001-05-10 |
| HU9502918D0 (en) | 1995-11-28 |
| TW401301B (en) | 2000-08-11 |
| CN1128657A (zh) | 1996-08-14 |
| HUT73422A (en) | 1996-07-29 |
| EP0705607A2 (en) | 1996-04-10 |
| CA2160092A1 (en) | 1996-04-08 |
| NO953961D0 (no) | 1995-10-05 |
| AU703422B2 (en) | 1999-03-25 |
| EP0705607A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1996-05-08 |
| FI954773A0 (fi) | 1995-10-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN APRIL 2003 |