NO306468B1 - New phospholipid derivatives, their preparation, drug containing the derivatives and the use of the derivatives - Google Patents

New phospholipid derivatives, their preparation, drug containing the derivatives and the use of the derivatives

Info

Publication number
NO306468B1
NO306468B1 NO932502A NO932502A NO306468B1 NO 306468 B1 NO306468 B1 NO 306468B1 NO 932502 A NO932502 A NO 932502A NO 932502 A NO932502 A NO 932502A NO 306468 B1 NO306468 B1 NO 306468B1
Authority
NO
Norway
Prior art keywords
derivatives
preparation
drug containing
new phospholipid
new
Prior art date
Application number
NO932502A
Other languages
Norwegian (no)
Other versions
NO932502D0 (en
NO932502L (en
Inventor
Gerhard Noessner
Bernhard Kutscher
Juergen Engel
Wolfgang Schumacher
Jurij Stekar
Peter Hilgard
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of NO932502D0 publication Critical patent/NO932502D0/en
Publication of NO932502L publication Critical patent/NO932502L/en
Publication of NO306468B1 publication Critical patent/NO306468B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C07F9/106—Adducts, complexes, salts of phosphatides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/5532—Seven-(or more) membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/59—Hydrogenated pyridine rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • AIDS & HIV (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)

Abstract

Novel phospholipid derivatives, preparation processes therefor and their use as medicaments are described.
NO932502A 1992-07-11 1993-07-08 New phospholipid derivatives, their preparation, drug containing the derivatives and the use of the derivatives NO306468B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4222910A DE4222910A1 (en) 1992-07-11 1992-07-11 New phospholipid derivatives

Publications (3)

Publication Number Publication Date
NO932502D0 NO932502D0 (en) 1993-07-08
NO932502L NO932502L (en) 1994-01-12
NO306468B1 true NO306468B1 (en) 1999-11-08

Family

ID=6463031

Family Applications (1)

Application Number Title Priority Date Filing Date
NO932502A NO306468B1 (en) 1992-07-11 1993-07-08 New phospholipid derivatives, their preparation, drug containing the derivatives and the use of the derivatives

Country Status (31)

Country Link
EP (1) EP0579939B1 (en)
JP (1) JP3311431B2 (en)
KR (1) KR100297180B1 (en)
CN (1) CN1039012C (en)
AT (1) ATE176477T1 (en)
AU (1) AU664101B2 (en)
BR (1) BR9302809A (en)
CA (2) CA2100228C (en)
CZ (1) CZ290863B6 (en)
DE (2) DE4222910A1 (en)
DK (1) DK0579939T3 (en)
EE (1) EE03140B1 (en)
ES (1) ES2129053T3 (en)
FI (1) FI111262B (en)
GR (1) GR3029602T3 (en)
HR (1) HRP931046B1 (en)
HU (1) HU218783B (en)
IL (1) IL106289A (en)
LT (1) LT3113B (en)
LV (1) LV10870B (en)
MX (1) MX9304133A (en)
NO (1) NO306468B1 (en)
PL (3) PL175607B1 (en)
RU (1) RU2108336C1 (en)
SG (1) SG46249A1 (en)
SI (1) SI9300365B (en)
SK (1) SK283827B6 (en)
TW (1) TW304956B (en)
UA (1) UA40567C2 (en)
YU (1) YU49079B (en)
ZA (1) ZA934971B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006077424A1 (en) 2005-01-21 2006-07-27 Astex Therapeutics Limited Pharmaceutical compounds
AR058397A1 (en) * 2005-12-19 2008-01-30 Zentaris Gmbh DERIVATIVES OF ALQUILFOSFOLIPIDOS WITH REDUCED CYTOTOXICITY AND USES OF THE SAME
EP1800684A1 (en) * 2005-12-20 2007-06-27 Zentaris GmbH Novel alkyl phospholipid derivatives and uses thereof
EP1869981A1 (en) * 2006-06-21 2007-12-26 Staatliches Weinbauinstitut Freiburg Alkylphospholipids and lysophospholipids for controlling plant pathogens
WO2008044045A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3164332D1 (en) * 1980-10-21 1984-07-26 Boehringer Mannheim Gmbh Phospholipids that contain sulphur, process for their preparation and medicines containing these compounds
JPS5984824A (en) * 1982-11-08 1984-05-16 Takeda Chem Ind Ltd Antitumor agent
DE3530767A1 (en) * 1985-08-28 1987-03-12 Max Planck Gesellschaft AGENT AGAINST MULTIPLE Sclerosis
IE59778B1 (en) * 1985-12-04 1994-04-06 Max Planck Gesellschaft Medicament with anti-tumour action containing hexadecylphosphocholine
DE3765502D1 (en) * 1986-07-14 1990-11-15 Nippon Chemiphar Co GLYCEROL DERIVATIVE AND ANTI-HYPERTENSIVE AGENT.
ES2058260T3 (en) * 1987-03-24 1994-11-01 Nippon Chemiphar Co A PROCESS FOR THE PREPARATION OF A GLYCEROL DERIVATIVE.
DE3906952A1 (en) * 1989-03-04 1990-09-06 Boehringer Mannheim Gmbh (3- (C (DOWN ARROW)) (DOWN ARROW) (DOWN ARROW) 6 (DOWN ARROW) -C (DOWN ARROW) 1 (DOWN ARROW) (DOWN ARROW) 8 (DOWN ARROW)) ALKANSULFINYL AND 2 SULPHONE -METHOXYMETHYL-PROPYL) - (2-TRIMETHYLAMMONIO-ETHYL) PHOSPHATES, METHOD FOR PRODUCING THE MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
DE3942933A1 (en) * 1989-12-23 1991-06-27 Boehringer Mannheim Gmbh USE OF ALKYLPHOSPHOLIPIDES AS ANTIVIRAL MEDICINAL PRODUCTS AND NEW PHOSPHOLIPID DERIVATIVES
DE4114586A1 (en) * 1991-05-04 1992-11-05 Boehringer Mannheim Gmbh MEDICINAL PRODUCTS CONTAINING AZACYCLODIPHOSPHONIC ACID DERIVATIVES, NEW AZACYCLODIPHOSPHONIC ACID DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF

Also Published As

Publication number Publication date
FI111262B (en) 2003-06-30
AU4186493A (en) 1994-01-13
DK0579939T3 (en) 1999-09-20
LV10870A (en) 1995-10-20
CN1084175A (en) 1994-03-23
HUT64548A (en) 1994-01-28
ES2129053T3 (en) 1999-06-01
HU218783B (en) 2000-12-28
GR3029602T3 (en) 1999-06-30
NO932502D0 (en) 1993-07-08
SK67093A3 (en) 1995-03-08
EP0579939A1 (en) 1994-01-26
IL106289A (en) 2000-06-01
KR100297180B1 (en) 2001-11-30
PL175607B1 (en) 1999-01-29
TW304956B (en) 1997-05-11
LV10870B (en) 1996-06-20
FI933165A0 (en) 1993-07-09
NO932502L (en) 1994-01-12
LTIP620A (en) 1994-07-15
CZ124993A3 (en) 1995-03-15
DE59309355D1 (en) 1999-03-18
EE03140B1 (en) 1998-12-15
HRP931046A2 (en) 1997-04-30
CA2100228C (en) 2006-01-24
ATE176477T1 (en) 1999-02-15
CA2511753A1 (en) 1994-01-12
YU49079B (en) 2003-08-29
MX9304133A (en) 1994-04-29
IL106289A0 (en) 1994-04-12
PL173388B1 (en) 1998-02-27
UA40567C2 (en) 2001-08-15
HRP931046B1 (en) 2000-06-30
ZA934971B (en) 1994-02-01
SI9300365A (en) 1994-03-31
KR940002265A (en) 1994-02-17
JP3311431B2 (en) 2002-08-05
SK283827B6 (en) 2004-02-03
CZ290863B6 (en) 2002-11-13
HU9301992D0 (en) 1993-09-28
RU2108336C1 (en) 1998-04-10
CN1039012C (en) 1998-07-08
PL299624A1 (en) 1994-02-21
AU664101B2 (en) 1995-11-02
BR9302809A (en) 1994-03-15
CA2100228A1 (en) 1994-01-12
FI933165A (en) 1994-01-12
YU47393A (en) 1997-08-22
DE4222910A1 (en) 1994-01-13
CA2511753C (en) 2007-09-25
LT3113B (en) 1994-12-27
SG46249A1 (en) 1998-02-20
PL177811B1 (en) 2000-01-31
SI9300365B (en) 2002-02-28
JPH0733791A (en) 1995-02-03
EP0579939B1 (en) 1999-02-03

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Legal Events

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MK1K Patent expired