EE03140B1 - Phospholipid derivatives - Google Patents

Phospholipid derivatives

Info

Publication number
EE03140B1
EE03140B1 EE9400199A EE9400199A EE03140B1 EE 03140 B1 EE03140 B1 EE 03140B1 EE 9400199 A EE9400199 A EE 9400199A EE 9400199 A EE9400199 A EE 9400199A EE 03140 B1 EE03140 B1 EE 03140B1
Authority
EE
Estonia
Prior art keywords
phospholipid derivatives
derivatives
phospholipid
medicaments
preparation processes
Prior art date
Application number
EE9400199A
Other languages
Estonian (et)
Inventor
N�ssner Gerhard
Kutscher Bernhard
Engel J�rgen
Schumacher Wolfgang
Stekar Jurij
Hilgard Peter
Original Assignee
Asta Medica Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Aktiengesellschaft filed Critical Asta Medica Aktiengesellschaft
Publication of EE03140B1 publication Critical patent/EE03140B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C07F9/106—Adducts, complexes, salts of phosphatides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/5532—Seven-(or more) membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/59—Hydrogenated pyridine rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • AIDS & HIV (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)

Abstract

Novel phospholipid derivatives, preparation processes therefor and their use as medicaments are described.
EE9400199A 1992-07-11 1994-10-25 Phospholipid derivatives EE03140B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4222910A DE4222910A1 (en) 1992-07-11 1992-07-11 New phospholipid derivatives

Publications (1)

Publication Number Publication Date
EE03140B1 true EE03140B1 (en) 1998-12-15

Family

ID=6463031

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9400199A EE03140B1 (en) 1992-07-11 1994-10-25 Phospholipid derivatives

Country Status (31)

Country Link
EP (1) EP0579939B1 (en)
JP (1) JP3311431B2 (en)
KR (1) KR100297180B1 (en)
CN (1) CN1039012C (en)
AT (1) ATE176477T1 (en)
AU (1) AU664101B2 (en)
BR (1) BR9302809A (en)
CA (2) CA2100228C (en)
CZ (1) CZ290863B6 (en)
DE (2) DE4222910A1 (en)
DK (1) DK0579939T3 (en)
EE (1) EE03140B1 (en)
ES (1) ES2129053T3 (en)
FI (1) FI111262B (en)
GR (1) GR3029602T3 (en)
HR (1) HRP931046B1 (en)
HU (1) HU218783B (en)
IL (1) IL106289A (en)
LT (1) LT3113B (en)
LV (1) LV10870B (en)
MX (1) MX9304133A (en)
NO (1) NO306468B1 (en)
PL (3) PL175607B1 (en)
RU (1) RU2108336C1 (en)
SG (1) SG46249A1 (en)
SI (1) SI9300365B (en)
SK (1) SK283827B6 (en)
TW (1) TW304956B (en)
UA (1) UA40567C2 (en)
YU (1) YU49079B (en)
ZA (1) ZA934971B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006077424A1 (en) 2005-01-21 2006-07-27 Astex Therapeutics Limited Pharmaceutical compounds
AR058397A1 (en) * 2005-12-19 2008-01-30 Zentaris Gmbh DERIVATIVES OF ALQUILFOSFOLIPIDOS WITH REDUCED CYTOTOXICITY AND USES OF THE SAME
EP1800684A1 (en) * 2005-12-20 2007-06-27 Zentaris GmbH Novel alkyl phospholipid derivatives and uses thereof
EP1869981A1 (en) * 2006-06-21 2007-12-26 Staatliches Weinbauinstitut Freiburg Alkylphospholipids and lysophospholipids for controlling plant pathogens
WO2008044045A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3164332D1 (en) * 1980-10-21 1984-07-26 Boehringer Mannheim Gmbh Phospholipids that contain sulphur, process for their preparation and medicines containing these compounds
JPS5984824A (en) * 1982-11-08 1984-05-16 Takeda Chem Ind Ltd Antitumor agent
DE3530767A1 (en) * 1985-08-28 1987-03-12 Max Planck Gesellschaft AGENT AGAINST MULTIPLE Sclerosis
IE59778B1 (en) * 1985-12-04 1994-04-06 Max Planck Gesellschaft Medicament with anti-tumour action containing hexadecylphosphocholine
DE3765502D1 (en) * 1986-07-14 1990-11-15 Nippon Chemiphar Co GLYCEROL DERIVATIVE AND ANTI-HYPERTENSIVE AGENT.
ES2058260T3 (en) * 1987-03-24 1994-11-01 Nippon Chemiphar Co A PROCESS FOR THE PREPARATION OF A GLYCEROL DERIVATIVE.
DE3906952A1 (en) * 1989-03-04 1990-09-06 Boehringer Mannheim Gmbh (3- (C (DOWN ARROW)) (DOWN ARROW) (DOWN ARROW) 6 (DOWN ARROW) -C (DOWN ARROW) 1 (DOWN ARROW) (DOWN ARROW) 8 (DOWN ARROW)) ALKANSULFINYL AND 2 SULPHONE -METHOXYMETHYL-PROPYL) - (2-TRIMETHYLAMMONIO-ETHYL) PHOSPHATES, METHOD FOR PRODUCING THE MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
DE3942933A1 (en) * 1989-12-23 1991-06-27 Boehringer Mannheim Gmbh USE OF ALKYLPHOSPHOLIPIDES AS ANTIVIRAL MEDICINAL PRODUCTS AND NEW PHOSPHOLIPID DERIVATIVES
DE4114586A1 (en) * 1991-05-04 1992-11-05 Boehringer Mannheim Gmbh MEDICINAL PRODUCTS CONTAINING AZACYCLODIPHOSPHONIC ACID DERIVATIVES, NEW AZACYCLODIPHOSPHONIC ACID DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF

Also Published As

Publication number Publication date
FI111262B (en) 2003-06-30
AU4186493A (en) 1994-01-13
DK0579939T3 (en) 1999-09-20
LV10870A (en) 1995-10-20
CN1084175A (en) 1994-03-23
HUT64548A (en) 1994-01-28
ES2129053T3 (en) 1999-06-01
HU218783B (en) 2000-12-28
NO306468B1 (en) 1999-11-08
GR3029602T3 (en) 1999-06-30
NO932502D0 (en) 1993-07-08
SK67093A3 (en) 1995-03-08
EP0579939A1 (en) 1994-01-26
IL106289A (en) 2000-06-01
KR100297180B1 (en) 2001-11-30
PL175607B1 (en) 1999-01-29
TW304956B (en) 1997-05-11
LV10870B (en) 1996-06-20
FI933165A0 (en) 1993-07-09
NO932502L (en) 1994-01-12
LTIP620A (en) 1994-07-15
CZ124993A3 (en) 1995-03-15
DE59309355D1 (en) 1999-03-18
HRP931046A2 (en) 1997-04-30
CA2100228C (en) 2006-01-24
ATE176477T1 (en) 1999-02-15
CA2511753A1 (en) 1994-01-12
YU49079B (en) 2003-08-29
MX9304133A (en) 1994-04-29
IL106289A0 (en) 1994-04-12
PL173388B1 (en) 1998-02-27
UA40567C2 (en) 2001-08-15
HRP931046B1 (en) 2000-06-30
ZA934971B (en) 1994-02-01
SI9300365A (en) 1994-03-31
KR940002265A (en) 1994-02-17
JP3311431B2 (en) 2002-08-05
SK283827B6 (en) 2004-02-03
CZ290863B6 (en) 2002-11-13
HU9301992D0 (en) 1993-09-28
RU2108336C1 (en) 1998-04-10
CN1039012C (en) 1998-07-08
PL299624A1 (en) 1994-02-21
AU664101B2 (en) 1995-11-02
BR9302809A (en) 1994-03-15
CA2100228A1 (en) 1994-01-12
FI933165A (en) 1994-01-12
YU47393A (en) 1997-08-22
DE4222910A1 (en) 1994-01-13
CA2511753C (en) 2007-09-25
LT3113B (en) 1994-12-27
SG46249A1 (en) 1998-02-20
PL177811B1 (en) 2000-01-31
SI9300365B (en) 2002-02-28
JPH0733791A (en) 1995-02-03
EP0579939B1 (en) 1999-02-03

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