NO306254B1 - Bærer for oligonukleotidsyntese, fremgangsmÕte for fremstilling av denne og av DNA/RNA; samt forbindelse som kan festes til bæreren - Google Patents

Bærer for oligonukleotidsyntese, fremgangsmÕte for fremstilling av denne og av DNA/RNA; samt forbindelse som kan festes til bæreren

Info

Publication number
NO306254B1
NO306254B1 NO943667A NO943667A NO306254B1 NO 306254 B1 NO306254 B1 NO 306254B1 NO 943667 A NO943667 A NO 943667A NO 943667 A NO943667 A NO 943667A NO 306254 B1 NO306254 B1 NO 306254B1
Authority
NO
Norway
Prior art keywords
carrier
group
preparation
oligonucleotide synthesis
substituted
Prior art date
Application number
NO943667A
Other languages
English (en)
Other versions
NO943667D0 (no
NO943667L (no
Inventor
Michael Joseph Mclean
Andrew John Garman
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of NO943667D0 publication Critical patent/NO943667D0/no
Publication of NO943667L publication Critical patent/NO943667L/no
Publication of NO306254B1 publication Critical patent/NO306254B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20Oxygen atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO943667A 1992-04-03 1994-09-30 Bærer for oligonukleotidsyntese, fremgangsmÕte for fremstilling av denne og av DNA/RNA; samt forbindelse som kan festes til bæreren NO306254B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929207380A GB9207380D0 (en) 1992-04-03 1992-04-03 Compounds
PCT/GB1993/000693 WO1993020091A1 (en) 1992-04-03 1993-04-02 Support for oligonucleotide synthesis

Publications (3)

Publication Number Publication Date
NO943667D0 NO943667D0 (no) 1994-09-30
NO943667L NO943667L (no) 1994-09-30
NO306254B1 true NO306254B1 (no) 1999-10-11

Family

ID=10713444

Family Applications (1)

Application Number Title Priority Date Filing Date
NO943667A NO306254B1 (no) 1992-04-03 1994-09-30 Bærer for oligonukleotidsyntese, fremgangsmÕte for fremstilling av denne og av DNA/RNA; samt forbindelse som kan festes til bæreren

Country Status (11)

Country Link
US (2) US5681945A (no)
EP (1) EP0633890B1 (no)
JP (1) JPH07505386A (no)
AT (1) ATE170865T1 (no)
AU (1) AU671629B2 (no)
CA (1) CA2131993A1 (no)
DE (1) DE69320949T2 (no)
FI (1) FI111371B (no)
GB (1) GB9207380D0 (no)
NO (1) NO306254B1 (no)
WO (1) WO1993020091A1 (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9207380D0 (en) * 1992-04-03 1992-05-13 Ici Plc Compounds
US5869696A (en) * 1996-04-22 1999-02-09 Beckman Instruments, Inc. Universal solid supports and methods for their use
US5998604A (en) * 1997-09-15 1999-12-07 The Perkin-Elmer Corporation Polynucleotide purification method
US6451998B1 (en) 1999-10-18 2002-09-17 Agilent Technologies, Inc. Capping and de-capping during oligonucleotide synthesis
WO2001096357A2 (en) * 2000-06-13 2001-12-20 Proligo Llc Universal solid supports for solid phase oligosynthesis and methods for their preparation and use
EP1404695B1 (en) 2000-11-29 2013-04-10 Glen Research Corporation Universal supports for oligonucleotide synthesis
AU2003254178A1 (en) * 2002-07-31 2004-02-16 Isis Pharmaceuticals, Inc. Universal support media for synthesis of oligomeric compounds
US6653468B1 (en) * 2002-07-31 2003-11-25 Isis Pharmaceuticals, Inc. Universal support media for synthesis of oligomeric compounds
US20040242897A1 (en) * 2002-07-31 2004-12-02 Guzaev Andrei P. Universal support media for synthesis of oligomeric compounds
US7202264B2 (en) * 2003-01-31 2007-04-10 Isis Pharmaceuticals, Inc. Supports for oligomer synthesis
US20050130736A1 (en) * 2003-12-12 2005-06-16 Lottofone, Inc. Prepaid wagering card
JP5438922B2 (ja) * 2008-06-25 2014-03-12 日東電工株式会社 核酸の製造方法
JP5360763B2 (ja) * 2009-10-21 2013-12-04 日東電工株式会社 核酸固相合成用リンカー及び担体
US20130207323A1 (en) * 2010-10-26 2013-08-15 Sumitomo Chemical Company, Limited Sealing material and method for manufacturing ceramic honeycomb fired body
JP6028979B2 (ja) 2012-01-30 2016-11-24 日東電工株式会社 核酸固相合成用リンカー及び担体
EP2666794A1 (en) 2012-05-23 2013-11-27 Nitto Denko Corporation Solid-phase support for oligonucleotide synthesis and oligonucleotide synthesis method
JP6537338B2 (ja) 2015-04-24 2019-07-03 日東電工株式会社 核酸固相合成用リンカー及び担体
JP7198768B2 (ja) * 2017-03-29 2023-01-04 ロシュ イノベーション センター コペンハーゲン エーエス UnyLinker迅速切断方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
OA03606A (fr) * 1967-01-16 1971-03-30 Ciba Geigy Procédé de préparation de nouveaux dérivés glucidiques.
EP0067597A1 (en) * 1981-05-29 1982-12-22 ens BIO LOGICALS INC. Polynucleotide synthesis procedure
EP0155950B1 (en) * 1983-09-02 1990-01-17 Molecular Biosystems, Inc. Oligonucleotide polymeric support system
US4775619A (en) * 1984-10-16 1988-10-04 Chiron Corporation Polynucleotide determination with selectable cleavage sites
US5118605A (en) * 1984-10-16 1992-06-02 Chiron Corporation Polynucleotide determination with selectable cleavage sites
US4818681A (en) * 1985-02-22 1989-04-04 Molecular Diagnostics, Inc. Fast and specific immobilization of nucleic acids to solid supports
US5378825A (en) * 1990-07-27 1995-01-03 Isis Pharmaceuticals, Inc. Backbone modified oligonucleotide analogs
GB9021625D0 (en) * 1990-10-04 1990-11-21 Ici Plc Synthesis of oligonucleotides
IE922316A1 (en) * 1991-07-17 1993-01-27 Smithkline Beecham Corp Retroviral protease inhibitors
GB9207380D0 (en) * 1992-04-03 1992-05-13 Ici Plc Compounds

Also Published As

Publication number Publication date
NO943667D0 (no) 1994-09-30
CA2131993A1 (en) 1993-10-14
NO943667L (no) 1994-09-30
AU3898093A (en) 1993-11-08
EP0633890B1 (en) 1998-09-09
WO1993020091A1 (en) 1993-10-14
ATE170865T1 (de) 1998-09-15
GB9207380D0 (en) 1992-05-13
FI111371B (fi) 2003-07-15
US5886193A (en) 1999-03-23
DE69320949T2 (de) 1999-05-12
US5681945A (en) 1997-10-28
AU671629B2 (en) 1996-09-05
FI944567A0 (fi) 1994-09-30
JPH07505386A (ja) 1995-06-15
EP0633890A1 (en) 1995-01-18
FI944567A (fi) 1994-09-30
DE69320949D1 (de) 1998-10-15

Similar Documents

Publication Publication Date Title
NO306254B1 (no) Bærer for oligonukleotidsyntese, fremgangsmÕte for fremstilling av denne og av DNA/RNA; samt forbindelse som kan festes til bæreren
Walker et al. Identification of the covalently bound flavin of succinate dehydrogenase as 8α-(histidyl) flavin adenine dinucleotide
DE3752362D1 (de) Optisch aktive Verbindungen
HUP0202795A2 (hu) Pirimidin- és pirazinszármazékok, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk
DE3380958D1 (de) Beta-carboline, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
CA2257807A1 (en) Improved methods for the synthesis of chemical compounds having pde-iv inhibitory activity
NO168767C (no) Cyklopenta(d)pyrimidinderivater og fremgangsmaate til fremstilling derav
ES8706715A1 (es) Un procedimiento para preparar un derivado de uridina.
Ngai et al. Enzymes of the. beta.-ketoadipate pathway in Pseudomonas putida: kinetic and magnetic resonance studies of the cis, cis-muconate cycloisomerase catalyzed reaction
McDonald et al. Oncogenic purine N-oxide derivatives as substrates for sulfotransferase
AU7949900A (en) Process for producing optically active naphthalene derivative and optical resolver therefor
CA2331464A1 (en) Platinum complex, its preparation and therapeutic application
Takai et al. The reversibility of the adenylate cyclase reaction
HUP9903424A1 (hu) Új eritromicinszármazékok,eljárás előállításukra és gyógyszerként való alkalmazásuk
ATE254617T1 (de) Herstellung von n-arylsulfonamidverbindungen
LV10504A (lv) Mikrobiologiskais panemiens slapekli saturoso heterociklisko karbonskabju hidroksilesanai
DE68924010D1 (de) Verfahren zur Herstellung von 1-alpha,3-beta,24-Trihydroxy-delta-5-Steroidderivaten.
HUP0004658A2 (hu) Eljárás 1-fenil-pirazolin-3-karbonsav-származékok előállítására
JPS5251089A (en) Method of immobilizing glutathione-synthetase and process of producing glutathione with the immobilized synthetase
Sack Jr et al. Characterization of the products of alkylation of 2'-deoxyadenosine and 2'-deoxyguanosine by chloroethyl ethyl sulfide
HUT48229A (en) Process for producing 4-formyltetrahydropyran derivatives
RU2000297C1 (ru) 5-Аргиниламинонафталин-1-(алкоксиэтил)сульфонамиды в качестве субстратов дл АНСА-анализа ферментов, обладающих аминопептидазной активностью
DK1144436T3 (da) Fremgangsmåde til fremstilling af bicykliske forbindelser og anvendelse af denne fremgangsmåde til fremstilling af en ICE-inhiberende forbindelse
GR3002699T3 (en) Process for stabilising procaterol
Golankiewicz et al. 60-780 Poznari, Poland

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees