NO305253B1 - E. coli-bakterier og fremgangsmÕte for fremstilling av et °nsket, heterologt protein - Google Patents

E. coli-bakterier og fremgangsmÕte for fremstilling av et °nsket, heterologt protein Download PDF

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Publication number
NO305253B1
NO305253B1 NO921674A NO921674A NO305253B1 NO 305253 B1 NO305253 B1 NO 305253B1 NO 921674 A NO921674 A NO 921674A NO 921674 A NO921674 A NO 921674A NO 305253 B1 NO305253 B1 NO 305253B1
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NO
Norway
Prior art keywords
protein
bacterium
coli
dna
culture medium
Prior art date
Application number
NO921674A
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English (en)
Norwegian (no)
Other versions
NO921674L (no
NO921674D0 (no
Inventor
Charles A Lunn
Satwant K Narula
Richard L Reim
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of NO921674D0 publication Critical patent/NO921674D0/no
Publication of NO921674L publication Critical patent/NO921674L/no
Publication of NO305253B1 publication Critical patent/NO305253B1/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • C07K16/247IL-4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245Escherichia (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5406IL-4
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185Escherichia
    • C12R2001/19Escherichia coli

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO921674A 1989-10-31 1992-04-29 E. coli-bakterier og fremgangsmÕte for fremstilling av et °nsket, heterologt protein NO305253B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1989/004788 WO1991006655A1 (en) 1989-10-31 1989-10-31 E. coli secretory strains

Publications (3)

Publication Number Publication Date
NO921674D0 NO921674D0 (no) 1992-04-29
NO921674L NO921674L (no) 1992-06-29
NO305253B1 true NO305253B1 (no) 1999-04-26

Family

ID=22215324

Family Applications (1)

Application Number Title Priority Date Filing Date
NO921674A NO305253B1 (no) 1989-10-31 1992-04-29 E. coli-bakterier og fremgangsmÕte for fremstilling av et °nsket, heterologt protein

Country Status (10)

Country Link
EP (1) EP0497757B1 (de)
JP (1) JP2660095B2 (de)
KR (1) KR960013134B1 (de)
AU (1) AU651059B2 (de)
DE (1) DE68916444T2 (de)
FI (1) FI104499B (de)
HK (1) HK185296A (de)
HU (1) HU214828B (de)
NO (1) NO305253B1 (de)
WO (1) WO1991006655A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9203753D0 (sv) * 1992-12-11 1992-12-11 Kabi Pharmacia Ab Expression system for producing apolipoprotein ai-m
US5716612A (en) * 1994-09-07 1998-02-10 Schering Corporation Use of IL-4 for potentiation of chemotherapeutic agents
SE9500778D0 (sv) 1995-03-03 1995-03-03 Pharmacia Ab Process for producing a protein
SE9603068D0 (sv) * 1996-08-23 1996-08-23 Pharmacia & Upjohn Ab Process for purifying a protein
SE9603303D0 (sv) 1996-09-11 1996-09-11 Pharmacia & Upjohn Ab Process for purifying a protein
DE19915938A1 (de) * 1999-04-09 2000-10-19 Aventis Pharma Gmbh Herstellung von pankreatischer Procarboxypeptidase B, Isoformen und Muteinen davon und ihre Verwendung
DE502006009060D1 (de) 2006-09-22 2011-04-21 Wacker Chemie Ag Verfahren zur fermentativen Herstellung von Antikörpern
CN109370936A (zh) * 2018-10-25 2019-02-22 中国人民解放军军事科学院军事医学研究院 一株广谱抗噬菌体的大肠埃希氏菌bl21(de3)-pr及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2634856A1 (de) * 1976-08-03 1978-02-09 Hoechst Ag Verfahren zur herstellung von schwefelsaeurehalbester-verbindungen
JPS5936981B2 (ja) * 1979-08-09 1984-09-06 住友化学工業株式会社 アミノアリ−ル−β−スルファ−トエチルスルホンの製造法
JPS5936982B2 (ja) * 1979-08-14 1984-09-06 住友化学工業株式会社 アミノアリ−ル−β−スルファ−トエチルスルホンの製造法
US4595658A (en) * 1982-09-13 1986-06-17 The Rockefeller University Method for facilitating externalization of proteins synthesized in bacteria
US4757013A (en) * 1983-07-25 1988-07-12 The Research Foundation Of State University Of New York Cloning vehicles for polypeptide expression in microbial hosts
DE3340114A1 (de) * 1983-11-05 1985-05-15 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von 2-amino-1-hydroxy-4- oder -5- (ss-sulfatoaethylsulfonyl)-benzol-verbindungen und deren verwendung zur synthese von faserreaktiven verbindungen
AU3006789A (en) * 1988-02-24 1989-08-24 Smithkline Beckman Corporation Expression of hiv binding proteins

Also Published As

Publication number Publication date
NO921674L (no) 1992-06-29
EP0497757A1 (de) 1992-08-12
HK185296A (en) 1996-10-11
EP0497757B1 (de) 1994-06-22
FI921874A0 (fi) 1992-04-27
AU651059B2 (en) 1994-07-14
JP2660095B2 (ja) 1997-10-08
DE68916444D1 (de) 1994-07-28
FI104499B (fi) 2000-02-15
FI921874A (fi) 1992-04-27
JPH04505548A (ja) 1992-10-01
DE68916444T2 (de) 1994-11-03
AU4644789A (en) 1991-05-31
HU214828B (hu) 1998-06-29
WO1991006655A1 (en) 1991-05-16
HUT64597A (en) 1994-01-28
NO921674D0 (no) 1992-04-29
HU9201411D0 (en) 1992-07-28
KR960013134B1 (ko) 1996-09-30

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