NO303120B1 - Heterocykliske iminobismetylen-bisfosfonsyrederivater, farmas÷ytiske midler inneholdende dem samt deres anvendelse - Google Patents
Heterocykliske iminobismetylen-bisfosfonsyrederivater, farmas÷ytiske midler inneholdende dem samt deres anvendelseInfo
- Publication number
- NO303120B1 NO303120B1 NO941336A NO941336A NO303120B1 NO 303120 B1 NO303120 B1 NO 303120B1 NO 941336 A NO941336 A NO 941336A NO 941336 A NO941336 A NO 941336A NO 303120 B1 NO303120 B1 NO 303120B1
- Authority
- NO
- Norway
- Prior art keywords
- iminobismethylene
- heterocyclic
- acid derivatives
- bisphosphonic acid
- pharmaceuticals containing
- Prior art date
Links
- -1 Heterocyclic iminobismethylene bisphosphonic acid derivatives Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
- C07F9/3817—Acids containing the structure (RX)2P(=X)-alk-N...P (X = O, S, Se)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6503—Five-membered rings
- C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6503—Five-membered rings
- C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
- C07F9/65068—Five-membered rings having the nitrogen atoms in positions 1 and 3 condensed with carbocyclic rings or carbocyclic ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Crystallography & Structural Chemistry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5087692A JPH06298779A (ja) | 1993-04-15 | 1993-04-15 | ヘテロ環イミノビスメチレンビスホスホン酸誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO941336D0 NO941336D0 (no) | 1994-04-14 |
| NO941336L NO941336L (no) | 1994-10-17 |
| NO303120B1 true NO303120B1 (no) | 1998-06-02 |
Family
ID=13921987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO941336A NO303120B1 (no) | 1993-04-15 | 1994-04-14 | Heterocykliske iminobismetylen-bisfosfonsyrederivater, farmas÷ytiske midler inneholdende dem samt deres anvendelse |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5441945A (fi) |
| EP (1) | EP0620227A1 (fi) |
| JP (1) | JPH06298779A (fi) |
| AU (1) | AU673895B2 (fi) |
| CA (1) | CA2121313A1 (fi) |
| FI (1) | FI941712A (fi) |
| HU (1) | HU217443B (fi) |
| NO (1) | NO303120B1 (fi) |
| TW (1) | TW279164B (fi) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4435496A1 (de) * | 1994-10-04 | 1996-04-11 | Hoechst Ag | Imidobisphosphorsäuren, Verfahren zu ihrer Herstellung und Verwendung derselben |
| ZA975198B (en) | 1996-06-13 | 1997-12-15 | Smithkline Beecham Corp | Improved process for preparing potassium clavulanate. |
| WO1998039344A1 (en) | 1997-03-07 | 1998-09-11 | Metabasis Therapeutics, Inc. | Novel purine inhibitors of fructose-1,6-bisphosphatase |
| EP1402895A1 (en) * | 1997-03-07 | 2004-03-31 | Metabasis Therapeutics, Inc. | Benzimidazole inhibitors of fructose 1,6-biphosphatase |
| ES2210728T3 (es) | 1997-03-07 | 2004-07-01 | Metabasis Therapeutics, Inc. | Nuevos inhibidores bencimidazol de la fructosa-1, 6-bifosfatasa. |
| AU6691798A (en) | 1997-03-07 | 1998-09-22 | Metabasis Therapeutics, Inc. | Novel indole and azaindole inhibitors of fructose-1,6-bisphosphatase |
| DK1112275T3 (da) | 1998-09-09 | 2003-11-24 | Metabasis Therapeutics Inc | Hidtil ukendte heteroaromatiske inhibitorer for fructose-1,6-bisphosphatase |
| FR2793796A1 (fr) * | 1999-04-14 | 2000-11-24 | Hoechst Marion Roussel Inc | Nouveaux derives d'imidazoles, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant |
| US6315566B1 (en) | 1999-05-18 | 2001-11-13 | 3M Innovative Properties Company | Dental materials |
| US6143919A (en) * | 1999-05-18 | 2000-11-07 | 3M Innovative Properties Company | Polymerizable acidic compounds and methods of preparation |
| US7563774B2 (en) | 2000-06-29 | 2009-07-21 | Metabasis Therapeutics, Inc. | Combination of FBPase inhibitors and antidiabetic agents useful for the treatment of diabetes |
| CN100358906C (zh) * | 2005-09-28 | 2008-01-02 | 南京大学 | N-(2-苯并咪唑基甲基)亚氨基双甲基膦酸的合成方法 |
| WO2012172271A1 (fr) * | 2011-06-17 | 2012-12-20 | Centre National De La Recherche Scientifique | Chélatants bifonctionnels phosphonates |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3674804A (en) * | 1968-10-17 | 1972-07-04 | Petrolite Corp | Imidazoline phosphonic acids |
| DE2224516A1 (de) * | 1972-05-19 | 1973-12-06 | Henkel & Cie Gmbh | Zahnsteinbildung verhindernde mundund zahnpflegemittel |
| JPS5952805A (ja) * | 1982-09-20 | 1984-03-27 | Konishiroku Photo Ind Co Ltd | 処理済み強磁性粉末 |
| DE3428524A1 (de) * | 1984-08-02 | 1986-02-13 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
| IL77243A (en) * | 1984-12-21 | 1996-11-14 | Procter & Gamble | Pharmaceutical compositions containing geminal diphosphonic acid compounds and certain such novel compounds |
| US5057505A (en) * | 1986-11-21 | 1991-10-15 | Ciba-Geigy Corporation | Substituted aminomethanediphosphonic acids and use in medicaments |
| EP0317505A1 (de) * | 1987-11-13 | 1989-05-24 | Ciba-Geigy Ag | Neue Azacycloalkylalkandiphosphonsäuren |
| US5190930A (en) * | 1987-12-11 | 1993-03-02 | Ciba-Geigy Corporation | Araliphatylaminoalkanediphosphonic acids |
| DE3822650A1 (de) * | 1988-07-05 | 1990-02-01 | Boehringer Mannheim Gmbh | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
| US4990503A (en) * | 1988-08-12 | 1991-02-05 | Yamanouchi Pharmaceutical Co., Ltd. | Heterocyclic bisphosphonic acid derivatives |
| US4917737A (en) * | 1989-03-13 | 1990-04-17 | Betz Laboratories, Inc. | Sealing composition and method for iron and zinc phosphating process |
| ATE133677T1 (de) * | 1990-12-19 | 1996-02-15 | Takeda Chemical Industries Ltd | Bisphosphonsäurederivate, ihre produktion und ihre verwendung |
| TW222637B (fi) * | 1991-12-12 | 1994-04-21 | Hoechst Ag |
-
1993
- 1993-04-15 JP JP5087692A patent/JPH06298779A/ja active Pending
-
1994
- 1994-04-11 EP EP94105550A patent/EP0620227A1/en not_active Withdrawn
- 1994-04-13 FI FI941712A patent/FI941712A/fi unknown
- 1994-04-13 AU AU59432/94A patent/AU673895B2/en not_active Ceased
- 1994-04-13 US US08/227,351 patent/US5441945A/en not_active Expired - Fee Related
- 1994-04-14 HU HU9401070A patent/HU217443B/hu not_active IP Right Cessation
- 1994-04-14 NO NO941336A patent/NO303120B1/no unknown
- 1994-04-14 CA CA002121313A patent/CA2121313A1/en not_active Abandoned
- 1994-04-25 TW TW083103655A patent/TW279164B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| NO941336L (no) | 1994-10-17 |
| TW279164B (fi) | 1996-06-21 |
| NO941336D0 (no) | 1994-04-14 |
| FI941712A (fi) | 1994-10-16 |
| US5441945A (en) | 1995-08-15 |
| HU217443B (hu) | 2000-01-28 |
| AU673895B2 (en) | 1996-11-28 |
| FI941712A0 (fi) | 1994-04-13 |
| CA2121313A1 (en) | 1994-10-16 |
| JPH06298779A (ja) | 1994-10-25 |
| HU9401070D0 (en) | 1994-07-28 |
| HUT68774A (en) | 1995-07-28 |
| EP0620227A1 (en) | 1994-10-19 |
| AU5943294A (en) | 1994-10-20 |
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