NO2968302T3 - - Google Patents
Info
- Publication number
- NO2968302T3 NO2968302T3 NO14725812A NO14725812A NO2968302T3 NO 2968302 T3 NO2968302 T3 NO 2968302T3 NO 14725812 A NO14725812 A NO 14725812A NO 14725812 A NO14725812 A NO 14725812A NO 2968302 T3 NO2968302 T3 NO 2968302T3
- Authority
- NO
- Norway
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261718966P | 2012-10-26 | 2012-10-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO2968302T3 true NO2968302T3 (OSRAM) | 2018-02-03 |
Family
ID=50545344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO14725812A NO2968302T3 (OSRAM) | 2012-10-26 | 2014-03-14 |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US9777038B2 (OSRAM) |
| EP (1) | EP2912013B1 (OSRAM) |
| JP (1) | JP6272888B2 (OSRAM) |
| KR (1) | KR102068381B1 (OSRAM) |
| CN (2) | CN108250264A (OSRAM) |
| AU (1) | AU2013334122B2 (OSRAM) |
| BR (1) | BR112015009395A2 (OSRAM) |
| CA (1) | CA2889592A1 (OSRAM) |
| CY (1) | CY1119731T1 (OSRAM) |
| DK (1) | DK2912013T3 (OSRAM) |
| ES (1) | ES2655034T3 (OSRAM) |
| HK (1) | HK1253301A1 (OSRAM) |
| HU (1) | HUE036887T2 (OSRAM) |
| IL (1) | IL238454B (OSRAM) |
| MX (1) | MX361653B (OSRAM) |
| NO (1) | NO2968302T3 (OSRAM) |
| NZ (2) | NZ745013A (OSRAM) |
| PL (1) | PL2912013T3 (OSRAM) |
| PT (1) | PT2912013T (OSRAM) |
| SG (1) | SG11201503247UA (OSRAM) |
| SM (1) | SMT201700602T1 (OSRAM) |
| WO (1) | WO2014066819A1 (OSRAM) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108250264A (zh) | 2012-10-26 | 2018-07-06 | 英特塞普特医药品公司 | 制备胆汁酸衍生物的方法 |
| LT3149019T (lt) | 2014-05-29 | 2020-02-25 | Bar Pharmaceuticals S.R.L. | Cholano dariniai, skirti naudoti fxr ir tgr5/gpbar1 medijuojamų ligų gydymui ir (arba) prevencijai |
| EA033445B1 (ru) | 2014-11-19 | 2019-10-31 | Nzp Uk Ltd | 5-бета-6-алкил-7-гидрокси-3-оновые стероиды в качестве промежуточных соединений для получения стероидных модуляторов fxr |
| WO2016079517A1 (en) | 2014-11-19 | 2016-05-26 | Dextra Laboratories Limited | 6-alkyl-7-hydroxy-4-en-3-one steroids as intermediates for the production of steroidal fxr modulators |
| EA033603B1 (ru) | 2014-11-19 | 2019-11-08 | Nzp Uk Ltd | 6-альфа-алкил-6,7-дионовые стероиды в качестве промежуточных соединений для получения стероидных модуляторов fxr |
| WO2016079519A1 (en) | 2014-11-19 | 2016-05-26 | Dextra Laboratories Limited | 6.alpha.-alkyl-3,7-dione steroids as intermediates for the production of steroidal fxr modulators |
| CN104672290B (zh) * | 2015-01-05 | 2017-06-06 | 北京普禄德医药科技有限公司 | 一种用于预防或治疗fxr‑介导的疾病的药物及其制备方法和用途 |
| EA036404B1 (ru) | 2015-02-06 | 2020-11-06 | Интерсепт Фармасьютикалз, Инк. | Фармацевтические композиции для комбинированной терапии |
| KR20180052756A (ko) * | 2015-09-24 | 2018-05-18 | 인터셉트 파마슈티컬즈, 인크. | 담즙산 유도체 제조를 위한 방법 및 중간체 |
| WO2017079062A1 (en) * | 2015-11-06 | 2017-05-11 | Intercept Pharmaceuticals, Inc. | Methods for the preparation of obeticholic acid and derivatives thereof |
| US20200262865A1 (en) * | 2016-02-15 | 2020-08-20 | Alexander Khoruts | Compositions and methods for treating clostridium associated diseases |
| KR102377338B1 (ko) | 2016-04-13 | 2022-03-21 | 인터셉트 파마슈티컬즈, 인크. | 암의 치료 방법 |
| TW201738254A (zh) * | 2016-04-19 | 2017-11-01 | 英特賽普醫藥品公司 | 奧貝膽酸及其衍生物之製備方法 |
| GB201608777D0 (en) | 2016-05-18 | 2016-06-29 | Dextra Lab Ltd | Compounds |
| GB201608776D0 (en) | 2016-05-18 | 2016-06-29 | Dextra Lab Ltd | Methods and compounds |
| BR112019006242A2 (pt) * | 2016-09-30 | 2019-06-18 | Intercept Pharmaceuticals Inc | formas cristalinas de um derivado de ácido biliar |
| AU2018307611A1 (en) | 2017-07-24 | 2020-02-06 | Intercept Pharmaceuticals, Inc. | Isotopically labeled bile acid derivatives |
| EP3660030A4 (en) * | 2017-07-26 | 2021-04-21 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | METHOD OF MANUFACTURING STEROID-DERIVATIVE FXR AGONISTS |
| GB201812382D0 (en) | 2018-07-30 | 2018-09-12 | Nzp Uk Ltd | Compounds |
| CA3142358A1 (en) | 2019-05-30 | 2020-12-03 | Intercept Pharmaceuticals, Inc. | Pharmaceutical compositions comprising a fxr agonist and a fibrate for use in the treatment of cholestatic liver disease |
| WO2021071837A1 (en) | 2019-10-07 | 2021-04-15 | Kallyope, Inc. | Gpr119 agonists |
| TW202140440A (zh) | 2020-02-28 | 2021-11-01 | 美商克力歐普股份有限公司 | Gpr40激動劑 |
| EP4153589A4 (en) | 2020-05-19 | 2024-06-12 | Kallyope, Inc. | AMPK ACTIVATORS |
| WO2021263039A1 (en) | 2020-06-26 | 2021-12-30 | Kallyope, Inc. | Ampk activators |
| JP7583398B2 (ja) | 2020-09-18 | 2024-11-14 | ソウル大学校産学協力団 | タウロデオキシコール酸ナトリウムの大量生産方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5216015A (en) * | 1991-02-05 | 1993-06-01 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Compounds having hypocholesterolemic properties |
| DE60205891T2 (de) | 2001-03-12 | 2006-06-22 | Intercept Pharmaceuticals, Inc. | Steroide als agonisten für fxr |
| EP1568706A1 (en) | 2004-02-26 | 2005-08-31 | Intercept Pharmaceuticals, Inc. | Novel steroid agonist for FXR |
| PL2040713T3 (pl) * | 2006-06-27 | 2014-11-28 | Intercept Pharmaceuticals Inc | Pochodne kwasów żółciowych jako ligandy FXR do zapobiegania lub leczenia chorób lub stanów, w których pośredniczy FXR |
| EP2303026B1 (en) * | 2008-06-17 | 2020-09-09 | Brigham Young University | Cationic steroid antimicrobial diagnostic, detection, screening and imaging methods |
| US8796249B2 (en) * | 2008-07-30 | 2014-08-05 | Intercept Pharmaceuticals, Inc. | TGR5 modulators and methods of use thereof |
| ES2774368T3 (es) * | 2008-11-19 | 2020-07-20 | Intercept Pharmaceuticals Inc | Moduladores de TGR5 y métodos de uso de los mismos |
| CN108250264A (zh) | 2012-10-26 | 2018-07-06 | 英特塞普特医药品公司 | 制备胆汁酸衍生物的方法 |
-
2013
- 2013-10-25 CN CN201810282054.XA patent/CN108250264A/zh active Pending
- 2013-10-25 HU HUE13849263A patent/HUE036887T2/hu unknown
- 2013-10-25 MX MX2015005286A patent/MX361653B/es active IP Right Grant
- 2013-10-25 EP EP13849263.2A patent/EP2912013B1/en not_active Not-in-force
- 2013-10-25 WO PCT/US2013/066917 patent/WO2014066819A1/en not_active Ceased
- 2013-10-25 PL PL13849263T patent/PL2912013T3/pl unknown
- 2013-10-25 SM SM20170602T patent/SMT201700602T1/it unknown
- 2013-10-25 CN CN201380068062.XA patent/CN105102425B/zh not_active Expired - Fee Related
- 2013-10-25 BR BR112015009395A patent/BR112015009395A2/pt not_active Application Discontinuation
- 2013-10-25 NZ NZ745013A patent/NZ745013A/en not_active IP Right Cessation
- 2013-10-25 AU AU2013334122A patent/AU2013334122B2/en not_active Ceased
- 2013-10-25 DK DK13849263.2T patent/DK2912013T3/en active
- 2013-10-25 SG SG11201503247UA patent/SG11201503247UA/en unknown
- 2013-10-25 ES ES13849263.2T patent/ES2655034T3/es active Active
- 2013-10-25 JP JP2015539862A patent/JP6272888B2/ja not_active Expired - Fee Related
- 2013-10-25 KR KR1020157012805A patent/KR102068381B1/ko not_active Expired - Fee Related
- 2013-10-25 PT PT138492632T patent/PT2912013T/pt unknown
- 2013-10-25 US US14/438,323 patent/US9777038B2/en active Active
- 2013-10-25 CA CA2889592A patent/CA2889592A1/en not_active Abandoned
- 2013-10-25 NZ NZ707389A patent/NZ707389A/en not_active IP Right Cessation
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2014
- 2014-03-14 NO NO14725812A patent/NO2968302T3/no unknown
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2015
- 2015-04-26 IL IL238454A patent/IL238454B/en active IP Right Grant
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2016
- 2016-02-24 HK HK18112593.6A patent/HK1253301A1/zh unknown
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2017
- 2017-08-21 US US15/681,609 patent/US10202414B2/en not_active Expired - Fee Related
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2018
- 2018-01-03 CY CY20181100003T patent/CY1119731T1/el unknown