NO2897610T3 - - Google Patents
Info
- Publication number
- NO2897610T3 NO2897610T3 NO13839158A NO13839158A NO2897610T3 NO 2897610 T3 NO2897610 T3 NO 2897610T3 NO 13839158 A NO13839158 A NO 13839158A NO 13839158 A NO13839158 A NO 13839158A NO 2897610 T3 NO2897610 T3 NO 2897610T3
- Authority
- NO
- Norway
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
- C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1079—Screening libraries by altering the phenotype or phenotypic trait of the host
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
- G01N2035/00742—Type of codes
- G01N2035/00752—Type of codes bar codes
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261666081P | 2012-06-29 | 2012-06-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO2897610T3 true NO2897610T3 (no) | 2018-06-09 |
Family
ID=48747811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO13839158A NO2897610T3 (no) | 2012-06-29 | 2013-09-19 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9315806B2 (no) |
| EP (1) | EP2867361B1 (no) |
| JP (1) | JP6401700B2 (no) |
| CN (1) | CN104508130B (no) |
| AU (1) | AU2013282323B2 (no) |
| CA (1) | CA2877962C (no) |
| DK (1) | DK2867361T3 (no) |
| ES (1) | ES2663424T3 (no) |
| HK (2) | HK1207886A1 (no) |
| NO (1) | NO2897610T3 (no) |
| PL (1) | PL2867361T3 (no) |
| PT (1) | PT2867361T (no) |
| SG (1) | SG11201408736SA (no) |
| WO (1) | WO2014005042A2 (no) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2853829C (en) | 2011-07-22 | 2023-09-26 | President And Fellows Of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| JP6232074B2 (ja) * | 2012-12-19 | 2017-11-15 | ヘルゲ・ジーラー | 改変され、そして改善された細胞および生物を生成するための組成物および方法 |
| US20150044192A1 (en) | 2013-08-09 | 2015-02-12 | President And Fellows Of Harvard College | Methods for identifying a target site of a cas9 nuclease |
| US9359599B2 (en) | 2013-08-22 | 2016-06-07 | President And Fellows Of Harvard College | Engineered transcription activator-like effector (TALE) domains and uses thereof |
| US9322037B2 (en) | 2013-09-06 | 2016-04-26 | President And Fellows Of Harvard College | Cas9-FokI fusion proteins and uses thereof |
| US9228207B2 (en) | 2013-09-06 | 2016-01-05 | President And Fellows Of Harvard College | Switchable gRNAs comprising aptamers |
| US9526784B2 (en) | 2013-09-06 | 2016-12-27 | President And Fellows Of Harvard College | Delivery system for functional nucleases |
| EP3066201B1 (en) | 2013-11-07 | 2018-03-07 | Editas Medicine, Inc. | Crispr-related methods and compositions with governing grnas |
| US11053481B2 (en) | 2013-12-12 | 2021-07-06 | President And Fellows Of Harvard College | Fusions of Cas9 domains and nucleic acid-editing domains |
| AU2015288389B2 (en) * | 2014-07-07 | 2021-05-13 | Astrego Diagnostics Ab | Phenotypic characterization and in situ genotyping of a library of genetically different cells |
| WO2016011080A2 (en) | 2014-07-14 | 2016-01-21 | The Regents Of The University Of California | Crispr/cas transcriptional modulation |
| WO2016022363A2 (en) | 2014-07-30 | 2016-02-11 | President And Fellows Of Harvard College | Cas9 proteins including ligand-dependent inteins |
| WO2016070037A2 (en) * | 2014-10-31 | 2016-05-06 | Massachusetts Institute Of Technology | Massively parallel combinatorial genetics for crispr |
| WO2016115033A1 (en) * | 2015-01-12 | 2016-07-21 | Massachusetts Institute Of Technology | Microrna combinations for anti-cancer therapeutics |
| US10167457B2 (en) | 2015-10-23 | 2019-01-01 | President And Fellows Of Harvard College | Nucleobase editors and uses thereof |
| EP3448996A1 (en) * | 2016-04-26 | 2019-03-06 | Massachusetts Institute of Technology | Extensible recombinase cascades |
| EP4219731A3 (en) * | 2016-05-18 | 2023-08-09 | Amyris, Inc. | Compositions and methods for genomic integration of nucleic acids into exogenous landing pads |
| IL308426A (en) | 2016-08-03 | 2024-01-01 | Harvard College | Adenosine nuclear base editors and their uses |
| CN109804066A (zh) | 2016-08-09 | 2019-05-24 | 哈佛大学的校长及成员们 | 可编程cas9-重组酶融合蛋白及其用途 |
| WO2018039438A1 (en) | 2016-08-24 | 2018-03-01 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
| CN107784198B (zh) * | 2016-08-26 | 2021-06-15 | 深圳华大基因科技服务有限公司 | 一种二代序列和三代单分子实时测序序列联合组装方法和系统 |
| AU2017342543A1 (en) | 2016-10-14 | 2019-05-02 | President And Fellows Of Harvard College | AAV delivery of nucleobase editors |
| WO2018081113A1 (en) | 2016-10-24 | 2018-05-03 | Sawaya Sterling | Concealing information present within nucleic acids |
| WO2018119359A1 (en) | 2016-12-23 | 2018-06-28 | President And Fellows Of Harvard College | Editing of ccr5 receptor gene to protect against hiv infection |
| US11898179B2 (en) | 2017-03-09 | 2024-02-13 | President And Fellows Of Harvard College | Suppression of pain by gene editing |
| US11542496B2 (en) | 2017-03-10 | 2023-01-03 | President And Fellows Of Harvard College | Cytosine to guanine base editor |
| JP7191388B2 (ja) | 2017-03-23 | 2022-12-19 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 核酸によってプログラム可能なｄｎａ結合蛋白質を含む核酸塩基編集因子 |
| US11560566B2 (en) | 2017-05-12 | 2023-01-24 | President And Fellows Of Harvard College | Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation |
| US11293018B2 (en) | 2017-06-09 | 2022-04-05 | The Board Of Trustees Of The Leland Stanford Junior University | Manipulation of nuclear architecture |
| EP3658573A1 (en) | 2017-07-28 | 2020-06-03 | President and Fellows of Harvard College | Methods and compositions for evolving base editors using phage-assisted continuous evolution (pace) |
| US11319532B2 (en) | 2017-08-30 | 2022-05-03 | President And Fellows Of Harvard College | High efficiency base editors comprising Gam |
| EP3697906A1 (en) | 2017-10-16 | 2020-08-26 | The Broad Institute, Inc. | Uses of adenosine base editors |
| EP3853363A4 (en) | 2018-09-19 | 2022-12-14 | The University of Hong Kong | ENHANCED HIGH THROUGHPUT COMBINATORY GENE MODIFICATION SYSTEM AND OPTIMIZED CAS9 ENZYME VARIANTS |
| CN109801679B (zh) * | 2019-01-15 | 2021-02-02 | 广州柿宝生物科技有限公司 | 一种用于长链分子的数学序列重建方法 |
| DE112020001342T5 (de) | 2019-03-19 | 2022-01-13 | President and Fellows of Harvard College | Verfahren und Zusammensetzungen zum Editing von Nukleotidsequenzen |
| JP2023525304A (ja) | 2020-05-08 | 2023-06-15 | ザ ブロード インスティテュート，インコーポレーテッド | 標的二本鎖ヌクレオチド配列の両鎖同時編集のための方法および組成物 |
| WO2023022659A1 (en) | 2021-08-19 | 2023-02-23 | Engine Biosciences Pte. Ltd. | Compositions and methods for generating synthetic lethality in tumors |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US211103A (en) | 1879-01-07 | Improvement in nut-locks | ||
| DE60141533D1 (de) * | 2000-12-08 | 2010-04-22 | Life Technologies Corp | Ukleinsäuremolekülen unter verwendung multipler erkennungsstellen |
| CA2536565A1 (en) | 2003-09-10 | 2005-05-12 | Althea Technologies, Inc. | Expression profiling using microarrays |
| US20080269068A1 (en) | 2007-02-06 | 2008-10-30 | President And Fellows Of Harvard College | Multiplex decoding of sequence tags in barcodes |
| US8268564B2 (en) | 2007-09-26 | 2012-09-18 | President And Fellows Of Harvard College | Methods and applications for stitched DNA barcodes |
| US8221982B2 (en) * | 2008-11-19 | 2012-07-17 | Amyris, Inc. | Compositions and methods for the assembly of polynucleotides |
| US9255291B2 (en) | 2010-05-06 | 2016-02-09 | Bioo Scientific Corporation | Oligonucleotide ligation methods for improving data quality and throughput using massively parallel sequencing |
| WO2012019765A1 (en) | 2010-08-10 | 2012-02-16 | European Molecular Biology Laboratory (Embl) | Methods and systems for tracking samples and sample combinations |
-
2013
- 2013-06-28 AU AU2013282323A patent/AU2013282323B2/en active Active
- 2013-06-28 JP JP2015520583A patent/JP6401700B2/ja active Active
- 2013-06-28 SG SG11201408736SA patent/SG11201408736SA/en unknown
- 2013-06-28 EP EP13734638.3A patent/EP2867361B1/en active Active
- 2013-06-28 US US14/411,628 patent/US9315806B2/en active Active
- 2013-06-28 CN CN201380040777.4A patent/CN104508130B/zh active Active
- 2013-06-28 ES ES13734638.3T patent/ES2663424T3/es active Active
- 2013-06-28 PT PT137346383T patent/PT2867361T/pt unknown
- 2013-06-28 DK DK13734638.3T patent/DK2867361T3/da active
- 2013-06-28 PL PL13734638T patent/PL2867361T3/pl unknown
- 2013-06-28 WO PCT/US2013/048619 patent/WO2014005042A2/en active Application Filing
- 2013-06-28 CA CA2877962A patent/CA2877962C/en active Active
- 2013-09-19 NO NO13839158A patent/NO2897610T3/no unknown
-
2015
- 2015-09-01 HK HK15108525.0A patent/HK1207886A1/xx unknown
- 2015-11-06 HK HK15110947.6A patent/HK1210217A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN104508130A (zh) | 2015-04-08 |
| DK2867361T3 (da) | 2018-01-29 |
| EP2867361B1 (en) | 2017-11-01 |
| US9315806B2 (en) | 2016-04-19 |
| US20150141263A1 (en) | 2015-05-21 |
| WO2014005042A2 (en) | 2014-01-03 |
| AU2013282323A1 (en) | 2015-02-19 |
| ES2663424T3 (es) | 2018-04-12 |
| CA2877962C (en) | 2018-06-05 |
| CN104508130B (zh) | 2016-09-28 |
| PL2867361T3 (pl) | 2018-07-31 |
| PT2867361T (pt) | 2018-02-07 |
| HK1207886A1 (en) | 2016-02-12 |
| WO2014005042A3 (en) | 2014-02-27 |
| JP6401700B2 (ja) | 2018-10-10 |
| AU2013282323B2 (en) | 2018-05-10 |
| HK1210217A1 (en) | 2016-04-15 |
| JP2015521850A (ja) | 2015-08-03 |
| SG11201408736SA (en) | 2015-03-30 |
| EP2867361A2 (en) | 2015-05-06 |
| CA2877962A1 (en) | 2014-01-03 |